Result of FASTA (omim) for
pF1KB8440
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8440, 421 aa
1>>>pF1KB8440 421 - 421 aa - 421 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.9020+/-0.000537; mu= -24.5692+/- 0.034
mean_var=783.4656+/-159.397, 0's: 0 Z-trim(125.0): 231 B-trim: 0 in 0/62
Lambda= 0.045821
statistics sampled from 47555 (47822) to 47555 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.804), E-opt: 0.2 (0.561), width: 16
Scan time: 8.010
The best scores are: opt bits E(85289)
NP_001088 (OMIM: 102480) acrosin precursor [Homo s ( 421) 3025 214.7 3.4e-55
XP_006723244 (OMIM: 142440) PREDICTED: serine prot ( 417) 656 58.1 4.7e-08
NP_002142 (OMIM: 142440) serine protease hepsin pr ( 417) 656 58.1 4.7e-08
XP_005258895 (OMIM: 142440) PREDICTED: serine prot ( 417) 656 58.1 4.7e-08
NP_892028 (OMIM: 142440) serine protease hepsin pr ( 417) 656 58.1 4.7e-08
XP_016882220 (OMIM: 142440) PREDICTED: serine prot ( 417) 656 58.1 4.7e-08
XP_016882221 (OMIM: 142440) PREDICTED: serine prot ( 393) 655 58.0 4.8e-08
XP_016878460 (OMIM: 610560) PREDICTED: polyserase- ( 621) 658 58.4 5.7e-08
XP_016878459 (OMIM: 610560) PREDICTED: polyserase- ( 634) 658 58.5 5.7e-08
XP_016878458 (OMIM: 610560) PREDICTED: polyserase- ( 637) 658 58.5 5.8e-08
NP_001245220 (OMIM: 610560) polyserase-2 isoform 3 ( 752) 658 58.5 6.5e-08
XP_016878457 (OMIM: 610560) PREDICTED: polyserase- ( 761) 658 58.5 6.5e-08
NP_001245219 (OMIM: 610560) polyserase-2 isoform 2 ( 850) 658 58.6 7e-08
NP_775773 (OMIM: 610560) polyserase-2 isoform 1 pr ( 855) 658 58.6 7e-08
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 608 54.9 3.6e-07
XP_011520753 (OMIM: 613797) PREDICTED: serine prot ( 280) 601 54.3 4.5e-07
NP_690851 (OMIM: 613797) serine protease 33 precur ( 280) 601 54.3 4.5e-07
XP_011520754 (OMIM: 613797) PREDICTED: serine prot ( 280) 601 54.3 4.5e-07
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 608 55.0 4.5e-07
NP_002764 (OMIM: 600823) prostasin preproprotein [ ( 343) 602 54.5 4.9e-07
NP_892018 (OMIM: 610477) transmembrane protease se (1059) 606 55.3 8.8e-07
XP_011526280 (OMIM: 610477) PREDICTED: transmembra (1093) 606 55.3 9e-07
NP_071402 (OMIM: 609343) brain-specific serine pro ( 317) 587 53.4 9.3e-07
XP_005255530 (OMIM: 609343) PREDICTED: brain-speci ( 317) 587 53.4 9.3e-07
NP_006790 (OMIM: 608159) testisin isoform 1 prepro ( 314) 585 53.3 1e-06
NP_114154 (OMIM: 608018) serine protease 27 isofor ( 290) 576 52.7 1.4e-06
NP_001275679 (OMIM: 606751) transmembrane protease ( 413) 576 52.8 1.8e-06
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384) 574 52.7 1.9e-06
NP_001275680 (OMIM: 606751) transmembrane protease ( 448) 576 52.9 1.9e-06
NP_110397 (OMIM: 606751) transmembrane protease se ( 457) 576 52.9 2e-06
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452) 574 52.8 2.1e-06
NP_005647 (OMIM: 602060) transmembrane protease se ( 492) 574 52.8 2.3e-06
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492) 574 52.8 2.3e-06
NP_001128571 (OMIM: 602060) transmembrane protease ( 529) 574 52.8 2.4e-06
XP_011532764 (OMIM: 234000,610618,610619) PREDICTE ( 503) 573 52.7 2.4e-06
NP_003610 (OMIM: 249500,606709) neurotrypsin precu ( 875) 579 53.4 2.7e-06
NP_000496 (OMIM: 234000,610618,610619) coagulation ( 615) 573 52.8 2.8e-06
NP_659205 (OMIM: 608159) testisin isoform 2 prepro ( 312) 555 51.3 4e-06
NP_003285 (OMIM: 191080) tryptase alpha/beta-1 pre ( 275) 547 50.7 5.3e-06
NP_077078 (OMIM: 191081) tryptase beta-2 prepropro ( 275) 546 50.7 5.5e-06
NP_068813 (OMIM: 606797) suppressor of tumorigenic ( 855) 548 51.3 1.1e-05
NP_001231924 (OMIM: 610050) transmembrane protease ( 563) 541 50.7 1.1e-05
NP_001193718 (OMIM: 610050) transmembrane protease ( 532) 535 50.2 1.4e-05
NP_001070731 (OMIM: 610050) transmembrane protease ( 567) 535 50.3 1.5e-05
NP_001519 (OMIM: 604552) hepatocyte growth factor ( 655) 528 49.9 2.3e-05
NP_001284368 (OMIM: 604552) hepatocyte growth fact ( 662) 528 49.9 2.3e-05
NP_036599 (OMIM: 609341) tryptase gamma preproprot ( 321) 516 48.8 2.4e-05
XP_011520748 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 516 48.8 2.5e-05
XP_011520749 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 516 48.8 2.5e-05
NP_001243246 (OMIM: 605511) transmembrane protease ( 453) 506 48.3 4.8e-05
>>NP_001088 (OMIM: 102480) acrosin precursor [Homo sapie (421 aa)
initn: 3025 init1: 3025 opt: 3025 Z-score: 1111.8 bits: 214.7 E(85289): 3.4e-55
Smith-Waterman score: 3025; 99.8% identity (100.0% similar) in 421 aa overlap (1-421:1-421)
10 20 30 40 50 60
pF1KB8 MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 QIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 QERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 GGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRVIQSA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
NP_001 GGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 TPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTST
370 380 390 400 410 420
pF1KB8 S
:
NP_001 S
>>XP_006723244 (OMIM: 142440) PREDICTED: serine protease (417 aa)
initn: 524 init1: 242 opt: 656 Z-score: 265.5 bits: 58.1 E(85289): 4.7e-08
Smith-Waterman score: 661; 40.4% identity (65.0% similar) in 280 aa overlap (23-293:148-408)
10 20 30 40 50
pF1KB8 MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHG
: :. :: : . : :::::. .. :
XP_006 FCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQD-CGRR--KLPVD--RIVGGRDTSLG
120 130 140 150 160 170
60 70 80 90 100 110
pF1KB8 AWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHD-WRLVFGAKEITYG
:::.:::. :.. : ::::::.. ::::::::: .: : . ::. :: .
XP_006 RWPWQVSLR---YDGA--HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA----VA
180 190 200 210 220
120 130 140 150 160
pF1KB8 NNKPVKAPLQERYVEKIIIHEKY------NSATEGNDIALVEITPPISCGRFIGPGCLPH
. .: : :. .. : : :: ..::::::... :. ..: : :::
XP_006 QASPHGLQLG---VQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA
230 240 250 260 270 280
170 180 190 200 210 220
pF1KB8 FKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVC
.: : . : :.::: . . . ...:.:::: .:. :.::....:.....: :
XP_006 AGQALVDG-KICTVTGWGNTQYYGQQ-AGVLQEARVPIISNDVCNGADFYGNQIKPKMFC
290 300 310 320 330
230 240 250 260 270 280
pF1KB8 AGYPVGKIDTCQGDSGGPLMCKDS--KESAYVVVGITSWGVGCARAKRPGIYTATWPYLN
:::: : ::.::::::::..:.:: . . . ::.:::.::: :..::.:: . . .
XP_006 AGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFRE
340 350 360 370 380 390
290 300 310 320 330 340
pF1KB8 WIASKIGSNALRVIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQ
:: . : ...
XP_006 WIFQAIKTHSEASGMVTQL
400 410
>>NP_002142 (OMIM: 142440) serine protease hepsin precur (417 aa)
initn: 524 init1: 242 opt: 656 Z-score: 265.5 bits: 58.1 E(85289): 4.7e-08
Smith-Waterman score: 661; 40.4% identity (65.0% similar) in 280 aa overlap (23-293:148-408)
10 20 30 40 50
pF1KB8 MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHG
: :. :: : . : :::::. .. :
NP_002 FCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQD-CGRR--KLPVD--RIVGGRDTSLG
120 130 140 150 160 170
60 70 80 90 100 110
pF1KB8 AWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHD-WRLVFGAKEITYG
:::.:::. :.. : ::::::.. ::::::::: .: : . ::. :: .
NP_002 RWPWQVSLR---YDGA--HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA----VA
180 190 200 210 220
120 130 140 150 160
pF1KB8 NNKPVKAPLQERYVEKIIIHEKY------NSATEGNDIALVEITPPISCGRFIGPGCLPH
. .: : :. .. : : :: ..::::::... :. ..: : :::
NP_002 QASPHGLQLG---VQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA
230 240 250 260 270 280
170 180 190 200 210 220
pF1KB8 FKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVC
.: : . : :.::: . . . ...:.:::: .:. :.::....:.....: :
NP_002 AGQALVDG-KICTVTGWGNTQYYGQQ-AGVLQEARVPIISNDVCNGADFYGNQIKPKMFC
290 300 310 320 330
230 240 250 260 270 280
pF1KB8 AGYPVGKIDTCQGDSGGPLMCKDS--KESAYVVVGITSWGVGCARAKRPGIYTATWPYLN
:::: : ::.::::::::..:.:: . . . ::.:::.::: :..::.:: . . .
NP_002 AGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFRE
340 350 360 370 380 390
290 300 310 320 330 340
pF1KB8 WIASKIGSNALRVIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQ
:: . : ...
NP_002 WIFQAIKTHSEASGMVTQL
400 410
>>XP_005258895 (OMIM: 142440) PREDICTED: serine protease (417 aa)
initn: 524 init1: 242 opt: 656 Z-score: 265.5 bits: 58.1 E(85289): 4.7e-08
Smith-Waterman score: 661; 40.4% identity (65.0% similar) in 280 aa overlap (23-293:148-408)
10 20 30 40 50
pF1KB8 MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHG
: :. :: : . : :::::. .. :
XP_005 FCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQD-CGRR--KLPVD--RIVGGRDTSLG
120 130 140 150 160 170
60 70 80 90 100 110
pF1KB8 AWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHD-WRLVFGAKEITYG
:::.:::. :.. : ::::::.. ::::::::: .: : . ::. :: .
XP_005 RWPWQVSLR---YDGA--HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA----VA
180 190 200 210 220
120 130 140 150 160
pF1KB8 NNKPVKAPLQERYVEKIIIHEKY------NSATEGNDIALVEITPPISCGRFIGPGCLPH
. .: : :. .. : : :: ..::::::... :. ..: : :::
XP_005 QASPHGLQLG---VQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA
230 240 250 260 270 280
170 180 190 200 210 220
pF1KB8 FKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVC
.: : . : :.::: . . . ...:.:::: .:. :.::....:.....: :
XP_005 AGQALVDG-KICTVTGWGNTQYYGQQ-AGVLQEARVPIISNDVCNGADFYGNQIKPKMFC
290 300 310 320 330
230 240 250 260 270 280
pF1KB8 AGYPVGKIDTCQGDSGGPLMCKDS--KESAYVVVGITSWGVGCARAKRPGIYTATWPYLN
:::: : ::.::::::::..:.:: . . . ::.:::.::: :..::.:: . . .
XP_005 AGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFRE
340 350 360 370 380 390
290 300 310 320 330 340
pF1KB8 WIASKIGSNALRVIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQ
:: . : ...
XP_005 WIFQAIKTHSEASGMVTQL
400 410
>>NP_892028 (OMIM: 142440) serine protease hepsin precur (417 aa)
initn: 524 init1: 242 opt: 656 Z-score: 265.5 bits: 58.1 E(85289): 4.7e-08
Smith-Waterman score: 661; 40.4% identity (65.0% similar) in 280 aa overlap (23-293:148-408)
10 20 30 40 50
pF1KB8 MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHG
: :. :: : . : :::::. .. :
NP_892 FCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQD-CGRR--KLPVD--RIVGGRDTSLG
120 130 140 150 160 170
60 70 80 90 100 110
pF1KB8 AWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHD-WRLVFGAKEITYG
:::.:::. :.. : ::::::.. ::::::::: .: : . ::. :: .
NP_892 RWPWQVSLR---YDGA--HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA----VA
180 190 200 210 220
120 130 140 150 160
pF1KB8 NNKPVKAPLQERYVEKIIIHEKY------NSATEGNDIALVEITPPISCGRFIGPGCLPH
. .: : :. .. : : :: ..::::::... :. ..: : :::
NP_892 QASPHGLQLG---VQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA
230 240 250 260 270 280
170 180 190 200 210 220
pF1KB8 FKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVC
.: : . : :.::: . . . ...:.:::: .:. :.::....:.....: :
NP_892 AGQALVDG-KICTVTGWGNTQYYGQQ-AGVLQEARVPIISNDVCNGADFYGNQIKPKMFC
290 300 310 320 330
230 240 250 260 270 280
pF1KB8 AGYPVGKIDTCQGDSGGPLMCKDS--KESAYVVVGITSWGVGCARAKRPGIYTATWPYLN
:::: : ::.::::::::..:.:: . . . ::.:::.::: :..::.:: . . .
NP_892 AGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFRE
340 350 360 370 380 390
290 300 310 320 330 340
pF1KB8 WIASKIGSNALRVIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQ
:: . : ...
NP_892 WIFQAIKTHSEASGMVTQL
400 410
>>XP_016882220 (OMIM: 142440) PREDICTED: serine protease (417 aa)
initn: 524 init1: 242 opt: 656 Z-score: 265.5 bits: 58.1 E(85289): 4.7e-08
Smith-Waterman score: 661; 40.4% identity (65.0% similar) in 280 aa overlap (23-293:148-408)
10 20 30 40 50
pF1KB8 MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHG
: :. :: : . : :::::. .. :
XP_016 FCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQD-CGRR--KLPVD--RIVGGRDTSLG
120 130 140 150 160 170
60 70 80 90 100 110
pF1KB8 AWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHD-WRLVFGAKEITYG
:::.:::. :.. : ::::::.. ::::::::: .: : . ::. :: .
XP_016 RWPWQVSLR---YDGA--HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA----VA
180 190 200 210 220
120 130 140 150 160
pF1KB8 NNKPVKAPLQERYVEKIIIHEKY------NSATEGNDIALVEITPPISCGRFIGPGCLPH
. .: : :. .. : : :: ..::::::... :. ..: : :::
XP_016 QASPHGLQLG---VQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA
230 240 250 260 270 280
170 180 190 200 210 220
pF1KB8 FKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVC
.: : . : :.::: . . . ...:.:::: .:. :.::....:.....: :
XP_016 AGQALVDG-KICTVTGWGNTQYYGQQ-AGVLQEARVPIISNDVCNGADFYGNQIKPKMFC
290 300 310 320 330
230 240 250 260 270 280
pF1KB8 AGYPVGKIDTCQGDSGGPLMCKDS--KESAYVVVGITSWGVGCARAKRPGIYTATWPYLN
:::: : ::.::::::::..:.:: . . . ::.:::.::: :..::.:: . . .
XP_016 AGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFRE
340 350 360 370 380 390
290 300 310 320 330 340
pF1KB8 WIASKIGSNALRVIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQ
:: . : ...
XP_016 WIFQAIKTHSEASGMVTQL
400 410
>>XP_016882221 (OMIM: 142440) PREDICTED: serine protease (393 aa)
initn: 522 init1: 242 opt: 655 Z-score: 265.5 bits: 58.0 E(85289): 4.8e-08
Smith-Waterman score: 660; 40.8% identity (64.5% similar) in 282 aa overlap (23-291:120-382)
10 20 30 40 50
pF1KB8 MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHG
: :. :: : . : :::::. .. :
XP_016 FCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQD-CGRR--KLPVD--RIVGGRDTSLG
90 100 110 120 130 140
60 70 80 90 100 110
pF1KB8 AWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHD-WRLVFGAKEITYG
:::.:::. :.. : ::::::.. ::::::::: .: : . ::. :: .
XP_016 RWPWQVSLR---YDGA--HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA----VA
150 160 170 180 190
120 130 140 150 160
pF1KB8 NNKPVKAPLQERYVEKIIIHEKY------NSATEGNDIALVEITPPISCGRFIGPGCLPH
. .: : :. .. : : :: ..::::::... :. ..: : :::
XP_016 QASPHGLQLG---VQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA
200 210 220 230 240 250
170 180 190 200 210 220
pF1KB8 FKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVC
.: : . : :.::: . . . ...:.:::: .:. :.::....:.....: :
XP_016 AGQALVDG-KICTVTGWGNTQYYGQQ-AGVLQEARVPIISNDVCNGADFYGNQIKPKMFC
260 270 280 290 300 310
230 240 250 260 270 280
pF1KB8 AGYPVGKIDTCQGDSGGPLMCKDS--KESAYVVVGITSWGVGCARAKRPGIYTATWPYLN
:::: : ::.::::::::..:.:: . . . ::.:::.::: :..::.:: . . .
XP_016 AGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFRE
320 330 340 350 360 370
290 300 310 320 330
pF1KB8 WIAS----KIGSNALRVIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRP
:: . :.::
XP_016 WIFQAIKVKVGSRWEPGWGRLGV
380 390
>>XP_016878460 (OMIM: 610560) PREDICTED: polyserase-2 is (621 aa)
initn: 522 init1: 160 opt: 658 Z-score: 264.1 bits: 58.4 E(85289): 5.7e-08
Smith-Waterman score: 658; 33.4% identity (58.3% similar) in 362 aa overlap (4-351:6-347)
10 20 30 40 50
pF1KB8 MVEMLPTAILLVLAVSVVAKDNA---TCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWP
.:: ..:.. . . .:.: : . : : . :. ..:::::. :: :.::
XP_016 MARHLLLPLVMLVISPIPGAFQDSALSPTQEEPEDLDCGR-PEPSARIVGGSNAQPGTWP
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 WMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVH---DWRLVFGAKEITYGN
:.:::. : :::::. :::.:::::. ..... .: ...:. ...
XP_016 WQVSLH-----HGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGV----HSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 NKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPR
. :. . . : : :.. .:... : :.::.... : : : . : :::. . . .
XP_016 DGPLDGA-HTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRASHRFVH
120 130 140 150 160
180 190 200 210 220
pF1KB8 GSQSCWVAGWGYIEEKAPRPSS-ILMEARVDLIDLDLCNSTQWYNG------RVQPTNVC
:. .::..::: ..: : : .:.:... :. :. : .. : .:
XP_016 GT-ACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLC
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB8 AGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWI
:::: :. :::::::::::.:... . . .::::.: ::.: .:::..::. : ::
XP_016 AGYPEGRRDTCQGDSGGPLVCEEGGR--WFQAGITSFGFGCGRRNRPGVFTAVATYEAWI
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB8 ASKI-GSNALRVIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQP
.. ::. : : : . : . . :: ::: : ::
XP_016 REQVMGSEP----GPAFPTQPQKTQSDPQEPREENCTIALP-ECGKAPRP-GAWPWEAQV
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB8 RPPPSPPPPPPPPASPLPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGK
: : :
XP_016 MVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQH
350 360 370 380 390 400
>>XP_016878459 (OMIM: 610560) PREDICTED: polyserase-2 is (634 aa)
initn: 522 init1: 160 opt: 658 Z-score: 264.0 bits: 58.5 E(85289): 5.7e-08
Smith-Waterman score: 658; 33.4% identity (58.3% similar) in 362 aa overlap (4-351:6-347)
10 20 30 40 50
pF1KB8 MVEMLPTAILLVLAVSVVAKDNA---TCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWP
.:: ..:.. . . .:.: : . : : . :. ..:::::. :: :.::
XP_016 MARHLLLPLVMLVISPIPGAFQDSALSPTQEEPEDLDCGR-PEPSARIVGGSNAQPGTWP
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 WMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVH---DWRLVFGAKEITYGN
:.:::. : :::::. :::.:::::. ..... .: ...:. ...
XP_016 WQVSLH-----HGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGV----HSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 NKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPR
. :. . . : : :.. .:... : :.::.... : : : . : :::. . . .
XP_016 DGPLDGA-HTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRASHRFVH
120 130 140 150 160
180 190 200 210 220
pF1KB8 GSQSCWVAGWGYIEEKAPRPSS-ILMEARVDLIDLDLCNSTQWYNG------RVQPTNVC
:. .::..::: ..: : : .:.:... :. :. : .. : .:
XP_016 GT-ACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLC
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB8 AGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWI
:::: :. :::::::::::.:... . . .::::.: ::.: .:::..::. : ::
XP_016 AGYPEGRRDTCQGDSGGPLVCEEGGR--WFQAGITSFGFGCGRRNRPGVFTAVATYEAWI
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB8 ASKI-GSNALRVIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQP
.. ::. : : : . : . . :: ::: : ::
XP_016 REQVMGSEP----GPAFPTQPQKTQSDPQEPREENCTIALP-ECGKAPRP-GAWPWEAQV
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB8 RPPPSPPPPPPPPASPLPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGK
: : :
XP_016 MVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQH
350 360 370 380 390 400
>>XP_016878458 (OMIM: 610560) PREDICTED: polyserase-2 is (637 aa)
initn: 522 init1: 160 opt: 658 Z-score: 264.0 bits: 58.5 E(85289): 5.8e-08
Smith-Waterman score: 658; 33.4% identity (58.3% similar) in 362 aa overlap (4-351:6-347)
10 20 30 40 50
pF1KB8 MVEMLPTAILLVLAVSVVAKDNA---TCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWP
.:: ..:.. . . .:.: : . : : . :. ..:::::. :: :.::
XP_016 MARHLLLPLVMLVISPIPGAFQDSALSPTQEEPEDLDCGR-PEPSARIVGGSNAQPGTWP
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 WMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVH---DWRLVFGAKEITYGN
:.:::. : :::::. :::.:::::. ..... .: ...:. ...
XP_016 WQVSLH-----HGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGV----HSQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 NKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPR
. :. . . : : :.. .:... : :.::.... : : : . : :::. . . .
XP_016 DGPLDGA-HTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRASHRFVH
120 130 140 150 160
180 190 200 210 220
pF1KB8 GSQSCWVAGWGYIEEKAPRPSS-ILMEARVDLIDLDLCNSTQWYNG------RVQPTNVC
:. .::..::: ..: : : .:.:... :. :. : .. : .:
XP_016 GT-ACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLC
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB8 AGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWI
:::: :. :::::::::::.:... . . .::::.: ::.: .:::..::. : ::
XP_016 AGYPEGRRDTCQGDSGGPLVCEEGGR--WFQAGITSFGFGCGRRNRPGVFTAVATYEAWI
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB8 ASKI-GSNALRVIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQP
.. ::. : : : . : . . :: ::: : ::
XP_016 REQVMGSEP----GPAFPTQPQKTQSDPQEPREENCTIALP-ECGKAPRP-GAWPWEAQV
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB8 RPPPSPPPPPPPPASPLPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGK
: : :
XP_016 MVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQH
350 360 370 380 390 400
421 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:34:01 2016 done: Sat Nov 5 21:34:02 2016
Total Scan time: 8.010 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]