Result of FASTA (omim) for pF1KE0009
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0009, 643 aa
  1>>>pF1KE0009 643 - 643 aa - 643 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.1371+/-0.000458; mu= -2.6745+/- 0.028
 mean_var=317.9434+/-65.177, 0's: 0 Z-trim(120.4): 237  B-trim: 1472 in 1/55
 Lambda= 0.071928
 statistics sampled from 35390 (35664) to 35390 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.418), width:  16
 Scan time: 12.270

The best scores are:                                      opt bits E(85289)
NP_001184225 (OMIM: 603479) extracellular matrix p ( 643) 4307 461.2 5.3e-129
NP_001184224 (OMIM: 603479) extracellular matrix p ( 677) 4167 446.7 1.3e-124
NP_001384 (OMIM: 603479) extracellular matrix prot ( 699) 3059 331.7 5.4e-90
XP_016869865 (OMIM: 603479) PREDICTED: extracellul ( 485) 1683 188.8   4e-47
XP_016869866 (OMIM: 603479) PREDICTED: extracellul ( 364) 1157 134.1 8.8e-31
XP_011538979 (OMIM: 608661) PREDICTED: podocan iso ( 402)  493 65.2 5.2e-10
XP_005270514 (OMIM: 608661) PREDICTED: podocan iso ( 613)  493 65.4 7.1e-10
NP_001186009 (OMIM: 608661) podocan isoform 2 [Hom ( 642)  493 65.4 7.3e-10
NP_001186010 (OMIM: 608661) podocan isoform 2 [Hom ( 642)  493 65.4 7.3e-10
XP_016855783 (OMIM: 608661) PREDICTED: podocan iso ( 652)  493 65.4 7.4e-10
NP_714914 (OMIM: 608661) podocan isoform 1 [Homo s ( 661)  493 65.4 7.5e-10
NP_060150 (OMIM: 603932,607850,608135) asporin iso ( 379)  483 64.1   1e-09
NP_001702 (OMIM: 300106,301870) biglycan prepropro ( 368)  458 61.5 6.1e-09
XP_016885213 (OMIM: 300106,301870) PREDICTED: bigl ( 368)  458 61.5 6.1e-09
NP_001911 (OMIM: 125255,610048) decorin isoform a  ( 359)  454 61.1 7.9e-09
XP_016874406 (OMIM: 125255,610048) PREDICTED: deco ( 359)  454 61.1 7.9e-09
XP_005268750 (OMIM: 125255,610048) PREDICTED: deco ( 359)  454 61.1 7.9e-09
NP_598010 (OMIM: 125255,610048) decorin isoform a  ( 359)  454 61.1 7.9e-09
XP_006719333 (OMIM: 125255,610048) PREDICTED: deco ( 359)  454 61.1 7.9e-09
NP_008966 (OMIM: 217300,603288) keratocan precurso ( 352)  445 60.2 1.5e-08
NP_002014 (OMIM: 600245) fibromodulin precursor [H ( 376)  434 59.1 3.5e-08
NP_958505 (OMIM: 601914) prolargin precursor [Homo ( 382)  430 58.6 4.7e-08
NP_002716 (OMIM: 601914) prolargin precursor [Homo ( 382)  430 58.6 4.7e-08
NP_938205 (OMIM: 604808,615271) leucine-rich repea ( 649)  378 53.5 2.9e-06
XP_011527507 (OMIM: 604808,615271) PREDICTED: leuc ( 649)  378 53.5 2.9e-06
XP_011527506 (OMIM: 604808,615271) PREDICTED: leuc ( 649)  378 53.5 2.9e-06
XP_005260739 (OMIM: 604808,615271) PREDICTED: leuc ( 649)  378 53.5 2.9e-06
NP_037413 (OMIM: 604808,615271) leucine-rich repea ( 649)  378 53.5 2.9e-06
NP_001180264 (OMIM: 603932,607850,608135) asporin  ( 242)  356 50.8 6.8e-06
NP_001073982 (OMIM: 603104) carboxypeptidase N sub ( 545)  364 51.9   7e-06
XP_005269337 (OMIM: 603104) PREDICTED: carboxypept ( 545)  364 51.9   7e-06
NP_001278917 (OMIM: 603104) carboxypeptidase N sub ( 545)  364 51.9   7e-06
NP_001333075 (OMIM: 604807) leucine-rich repeat tr ( 660)  363 51.9 8.6e-06
XP_016876618 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  363 51.9 8.6e-06
NP_037363 (OMIM: 604807) leucine-rich repeat trans ( 660)  363 51.9 8.6e-06
XP_016876624 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  363 51.9 8.6e-06
XP_011534913 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  363 51.9 8.6e-06
NP_001333074 (OMIM: 604807) leucine-rich repeat tr ( 660)  363 51.9 8.6e-06
XP_016876620 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  363 51.9 8.6e-06
XP_016876622 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  363 51.9 8.6e-06
XP_005267547 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  363 51.9 8.6e-06
NP_001333073 (OMIM: 604807) leucine-rich repeat tr ( 660)  363 51.9 8.6e-06
NP_001333072 (OMIM: 604807) leucine-rich repeat tr ( 660)  363 51.9 8.6e-06
XP_016876623 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  363 51.9 8.6e-06
XP_016876621 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  363 51.9 8.6e-06
XP_016876619 (OMIM: 604807) PREDICTED: leucine-ric ( 660)  363 51.9 8.6e-06
NP_004479 (OMIM: 173511) platelet glycoprotein V p ( 560)  361 51.6 8.8e-06
XP_011543185 (OMIM: 604806) PREDICTED: leucine-ric ( 674)  355 51.1 1.6e-05
NP_037412 (OMIM: 604806) leucine-rich repeat trans ( 674)  355 51.1 1.6e-05
XP_005273918 (OMIM: 604806) PREDICTED: leucine-ric ( 674)  355 51.1 1.6e-05


>>NP_001184225 (OMIM: 603479) extracellular matrix prote  (643 aa)
 initn: 4307 init1: 4307 opt: 4307  Z-score: 2437.0  bits: 461.2 E(85289): 5.3e-129
Smith-Waterman score: 4307; 99.8% identity (99.8% similar) in 643 aa overlap (1-643:1-643)

               10        20        30        40        50        60
pF1KE0 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIPQTTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATEQREPTNLLHKQLPPPQVGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATEQREPTNLLHKQLPPPQVGM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 DRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDSRGGDRKQRPGEERRLAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDSRGGDRKQRPGEERRLAH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 QQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRMPSRSPLPAPPRGTLRLPSGCSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRMPSRSPLPAPPRGTLRLPSGCSL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 SYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 GIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 LELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE0 ICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE0 LLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKS
              550       560       570       580       590       600

              610       620       630       640   
pF1KE0 IPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAFPLW
       :::::::::::::::::::::::::::::::::::::::::::
NP_001 IPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAFPLW
              610       620       630       640   

>>NP_001184224 (OMIM: 603479) extracellular matrix prote  (677 aa)
 initn: 4540 init1: 4167 opt: 4167  Z-score: 2358.2  bits: 446.7 E(85289): 1.3e-124
Smith-Waterman score: 4167; 99.5% identity (99.7% similar) in 624 aa overlap (1-624:1-624)

               10        20        30        40        50        60
pF1KE0 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIPQTTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATEQREPTNLLHKQLPPPQVGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATEQREPTNLLHKQLPPPQVGM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 DRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDSRGGDRKQRPGEERRLAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDSRGGDRKQRPGEERRLAH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 QQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRMPSRSPLPAPPRGTLRLPSGCSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRMPSRSPLPAPPRGTLRLPSGCSL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 SYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 GIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 LELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE0 ICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE0 LLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKS
              550       560       570       580       590       600

              610       620       630       640                    
pF1KE0 IPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAFPLW                 
       :::::::::::::::::::::: .                                    
NP_001 IPPGIQEMKALHFLRLNNNKIRNILPEEICNAEEDDDSNLEHLHLENNYIKIREIPSYTF
              610       620       630       640       650       660

>>NP_001384 (OMIM: 603479) extracellular matrix protein   (699 aa)
 initn: 4526 init1: 3044 opt: 3059  Z-score: 1736.6  bits: 331.7 E(85289): 5.4e-90
Smith-Waterman score: 4113; 96.1% identity (96.3% similar) in 646 aa overlap (1-624:1-646)

               10        20        30        40        50        60
pF1KE0 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIPQTTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
               70        80        90       100       110       120

              130       140       150       160                    
pF1KE0 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSAT--------------------
       ::::::::::::::::::::::::::::::::::::::::                    
NP_001 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATVSYSLLSGIALNDRNEFSGD
              130       140       150       160       170       180

                170       180       190       200       210        
pF1KE0 --EQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSEQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
              190       200       210       220       230       240

      220       230       240       250       260       270        
pF1KE0 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
              250       260       270       280       290       300

      280       290       300       310       320       330        
pF1KE0 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPD
              310       320       330       340       350       360

      340       350       360       370       380       390        
pF1KE0 EAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELK
              370       380       390       400       410       420

      400       410       420       430       440       450        
pF1KE0 VNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIP
              430       440       450       460       470       480

      460       470       480       490       500       510        
pF1KE0 QGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESI
              490       500       510       520       530       540

      520       530       540       550       560       570        
pF1KE0 DLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDR
              550       560       570       580       590       600

      580       590       600       610       620       630        
pF1KE0 VSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDV
       :::::::::::::::::::::::::::::::::::::::::::: .              
NP_001 VSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEICNAEEDDDS
              610       620       630       640       650       660

      640                                     
pF1KE0 AFPLW                                  
                                              
NP_001 NLEHLHLENNYIKIREIPSYTFSCIRSYSSIVLKPQNIK
              670       680       690         

>>XP_016869865 (OMIM: 603479) PREDICTED: extracellular m  (485 aa)
 initn: 1671 init1: 1671 opt: 1683  Z-score: 967.0  bits: 188.8 E(85289): 4e-47
Smith-Waterman score: 2740; 88.1% identity (90.2% similar) in 479 aa overlap (1-457:1-468)

               10        20        30        40        50        60
pF1KE0 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIPQTTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
               70        80        90       100       110       120

              130       140       150       160                    
pF1KE0 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSAT--------------------
       ::::::::::::::::::::::::::::::::::::::::                    
XP_016 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATVSYSLLSGIALNDRNEFSGD
              130       140       150       160       170       180

                170       180       190       200       210        
pF1KE0 --EQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSEQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
              190       200       210       220       230       240

      220       230       240       250       260       270        
pF1KE0 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
              250       260       270       280       290       300

      280       290       300       310       320       330        
pF1KE0 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPD
              310       320       330       340       350       360

      340       350       360       370       380       390        
pF1KE0 EAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELK
              370       380       390       400       410       420

      400       410       420       430       440       450        
pF1KE0 VNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIP
       :::::::::::::::      .   .::...   .::   : ::. :   :  . : .. 
XP_016 VNENNLQAIDEESLSG-----SYYSQGNKFT---TNP---KYLKNYAKYSLHCHVFCVMD
              430            440             450       460         

      460       470       480       490       500       510        
pF1KE0 QGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESI
                                                                   
XP_016 RQFCRFFVATNQCHVC                                            
     470       480                                                 

>>XP_016869866 (OMIM: 603479) PREDICTED: extracellular m  (364 aa)
 initn: 2381 init1: 1142 opt: 1157  Z-score: 673.6  bits: 134.1 E(85289): 8.8e-31
Smith-Waterman score: 2211; 92.9% identity (93.5% similar) in 353 aa overlap (1-331:1-353)

               10        20        30        40        50        60
pF1KE0 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIPQTTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEP
               70        80        90       100       110       120

              130       140       150       160                    
pF1KE0 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSAT--------------------
       ::::::::::::::::::::::::::::::::::::::::                    
XP_016 CTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATVSYSLLSGIALNDRNEFSGD
              130       140       150       160       170       180

                170       180       190       200       210        
pF1KE0 --EQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
         ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSEQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLY
              190       200       210       220       230       240

      220       230       240       250       260       270        
pF1KE0 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRM
              250       260       270       280       290       300

      280       290       300       310       320       330        
pF1KE0 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPD
       :::::::::::::::::::::::::::::::::::::::::::::::::::..       
XP_016 PSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTASEEVNAFE
              310       320       330       340       350       360

      340       350       360       370       380       390        
pF1KE0 EAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELK
                                                                   
XP_016 YGWK                                                        
                                                                   

>>XP_011538979 (OMIM: 608661) PREDICTED: podocan isoform  (402 aa)
 initn: 705 init1: 366 opt: 493  Z-score: 300.7  bits: 65.2 E(85289): 5.2e-10
Smith-Waterman score: 493; 31.2% identity (63.9% similar) in 324 aa overlap (312-634:18-336)

             290       300       310       320       330       340 
pF1KE0 SPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAF
                                     : ..:    : . .:.: .:.. .::  ::
XP_011              MFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAF
                            10        20        30        40       

             350       360       370       380       390       400 
pF1KE0 NGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNE
       . : .:..: :..: .:. :.  ..:  :..:  :....::: ..:. :: .:  :....
XP_011 SELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEK
        50        60        70        80        90       100       

             410       420       430       440       450       460 
pF1KE0 NNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGL
       : ....: . :. . .:  : :..:.: : ...::::. :: :  ..: .: .. .:.::
XP_011 NAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL
       110       120       130       140       150       160       

             470       480       490       500       510       520 
pF1KE0 PGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLS
       :  .. :.. .:::  : .  :  :  .. . : ::.:   ..   :. . . :.:.:::
XP_011 PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLS
       170       180       190       200       210       220       

             530       540       550        560       570       580
pF1KE0 YNKLYHVPSYLPKSLLHLVLLGNQIERIP-GYVFGHMEPGLEYLYLSFNKLADDGMDRVS
        :.:. .:  ::...  : .  :..  .  : . :  .  :. :::. :.: . ..   .
XP_011 GNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ--LRELYLTSNRLRSRALGPRA
       230       240       250       260         270       280     

              590       600       610       620       630       640
pF1KE0 FYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAF
       .    : :. : .  :.:  :: :. :  .:..: :.::::  :   ..... :      
XP_011 WVDLAH-LQLLDIAGNQLTEIPEGLPE--SLEYLYLQNNKISAVPANAFDSTPNLKGIFL
         290        300       310         320       330       340  

                                                                   
pF1KE0 PLW                                                         
                                                                   
XP_011 RFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR
            350       360       370       380       390       400  

>>XP_005270514 (OMIM: 608661) PREDICTED: podocan isoform  (613 aa)
 initn: 705 init1: 366 opt: 493  Z-score: 298.3  bits: 65.4 E(85289): 7.1e-10
Smith-Waterman score: 493; 31.2% identity (63.9% similar) in 324 aa overlap (312-634:229-547)

             290       300       310       320       330       340 
pF1KE0 SPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAF
                                     : ..:    : . .:.: .:.. .::  ::
XP_005 HNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAF
      200       210       220       230       240       250        

             350       360       370       380       390       400 
pF1KE0 NGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNE
       . : .:..: :..: .:. :.  ..:  :..:  :....::: ..:. :: .:  :....
XP_005 SELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEK
      260       270       280       290       300       310        

             410       420       430       440       450       460 
pF1KE0 NNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGL
       : ....: . :. . .:  : :..:.: : ...::::. :: :  ..: .: .. .:.::
XP_005 NAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL
      320       330       340       350       360       370        

             470       480       490       500       510       520 
pF1KE0 PGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLS
       :  .. :.. .:::  : .  :  :  .. . : ::.:   ..   :. . . :.:.:::
XP_005 PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLS
      380       390       400       410       420       430        

             530       540       550        560       570       580
pF1KE0 YNKLYHVPSYLPKSLLHLVLLGNQIERIP-GYVFGHMEPGLEYLYLSFNKLADDGMDRVS
        :.:. .:  ::...  : .  :..  .  : . :  .  :. :::. :.: . ..   .
XP_005 GNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ--LRELYLTSNRLRSRALGPRA
      440       450       460       470         480       490      

              590       600       610       620       630       640
pF1KE0 FYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAF
       .    : :. : .  :.:  :: :. :  .:..: :.::::  :   ..... :      
XP_005 WVDLAH-LQLLDIAGNQLTEIPEGLPE--SLEYLYLQNNKISAVPANAFDSTPNLKGIFL
        500        510       520         530       540       550   

                                                                   
pF1KE0 PLW                                                         
                                                                   
XP_005 RFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR
           560       570       580       590       600       610   

>>NP_001186009 (OMIM: 608661) podocan isoform 2 [Homo sa  (642 aa)
 initn: 705 init1: 366 opt: 493  Z-score: 298.0  bits: 65.4 E(85289): 7.3e-10
Smith-Waterman score: 493; 31.2% identity (63.9% similar) in 324 aa overlap (312-634:258-576)

             290       300       310       320       330       340 
pF1KE0 SPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAF
                                     : ..:    : . .:.: .:.. .::  ::
NP_001 HNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAF
       230       240       250       260       270       280       

             350       360       370       380       390       400 
pF1KE0 NGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNE
       . : .:..: :..: .:. :.  ..:  :..:  :....::: ..:. :: .:  :....
NP_001 SELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEK
       290       300       310       320       330       340       

             410       420       430       440       450       460 
pF1KE0 NNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGL
       : ....: . :. . .:  : :..:.: : ...::::. :: :  ..: .: .. .:.::
NP_001 NAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL
       350       360       370       380       390       400       

             470       480       490       500       510       520 
pF1KE0 PGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLS
       :  .. :.. .:::  : .  :  :  .. . : ::.:   ..   :. . . :.:.:::
NP_001 PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLS
       410       420       430       440       450       460       

             530       540       550        560       570       580
pF1KE0 YNKLYHVPSYLPKSLLHLVLLGNQIERIP-GYVFGHMEPGLEYLYLSFNKLADDGMDRVS
        :.:. .:  ::...  : .  :..  .  : . :  .  :. :::. :.: . ..   .
NP_001 GNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ--LRELYLTSNRLRSRALGPRA
       470       480       490       500         510       520     

              590       600       610       620       630       640
pF1KE0 FYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAF
       .    : :. : .  :.:  :: :. :  .:..: :.::::  :   ..... :      
NP_001 WVDLAH-LQLLDIAGNQLTEIPEGLPE--SLEYLYLQNNKISAVPANAFDSTPNLKGIFL
         530        540       550         560       570       580  

                                                                   
pF1KE0 PLW                                                         
                                                                   
NP_001 RFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR
            590       600       610       620       630       640  

>>NP_001186010 (OMIM: 608661) podocan isoform 2 [Homo sa  (642 aa)
 initn: 705 init1: 366 opt: 493  Z-score: 298.0  bits: 65.4 E(85289): 7.3e-10
Smith-Waterman score: 493; 31.2% identity (63.9% similar) in 324 aa overlap (312-634:258-576)

             290       300       310       320       330       340 
pF1KE0 SPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAF
                                     : ..:    : . .:.: .:.. .::  ::
NP_001 HNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAF
       230       240       250       260       270       280       

             350       360       370       380       390       400 
pF1KE0 NGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNE
       . : .:..: :..: .:. :.  ..:  :..:  :....::: ..:. :: .:  :....
NP_001 SELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEK
       290       300       310       320       330       340       

             410       420       430       440       450       460 
pF1KE0 NNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGL
       : ....: . :. . .:  : :..:.: : ...::::. :: :  ..: .: .. .:.::
NP_001 NAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL
       350       360       370       380       390       400       

             470       480       490       500       510       520 
pF1KE0 PGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLS
       :  .. :.. .:::  : .  :  :  .. . : ::.:   ..   :. . . :.:.:::
NP_001 PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLS
       410       420       430       440       450       460       

             530       540       550        560       570       580
pF1KE0 YNKLYHVPSYLPKSLLHLVLLGNQIERIP-GYVFGHMEPGLEYLYLSFNKLADDGMDRVS
        :.:. .:  ::...  : .  :..  .  : . :  .  :. :::. :.: . ..   .
NP_001 GNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ--LRELYLTSNRLRSRALGPRA
       470       480       490       500         510       520     

              590       600       610       620       630       640
pF1KE0 FYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAF
       .    : :. : .  :.:  :: :. :  .:..: :.::::  :   ..... :      
NP_001 WVDLAH-LQLLDIAGNQLTEIPEGLPE--SLEYLYLQNNKISAVPANAFDSTPNLKGIFL
         530        540       550         560       570       580  

                                                                   
pF1KE0 PLW                                                         
                                                                   
NP_001 RFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR
            590       600       610       620       630       640  

>>XP_016855783 (OMIM: 608661) PREDICTED: podocan isoform  (652 aa)
 initn: 705 init1: 366 opt: 493  Z-score: 297.9  bits: 65.4 E(85289): 7.4e-10
Smith-Waterman score: 493; 31.2% identity (63.9% similar) in 324 aa overlap (312-634:268-586)

             290       300       310       320       330       340 
pF1KE0 SPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAF
                                     : ..:    : . .:.: .:.. .::  ::
XP_016 HNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAF
       240       250       260       270       280       290       

             350       360       370       380       390       400 
pF1KE0 NGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNE
       . : .:..: :..: .:. :.  ..:  :..:  :....::: ..:. :: .:  :....
XP_016 SELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEK
       300       310       320       330       340       350       

             410       420       430       440       450       460 
pF1KE0 NNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGL
       : ....: . :. . .:  : :..:.: : ...::::. :: :  ..: .: .. .:.::
XP_016 NAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGL
       360       370       380       390       400       410       

             470       480       490       500       510       520 
pF1KE0 PGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLS
       :  .. :.. .:::  : .  :  :  .. . : ::.:   ..   :. . . :.:.:::
XP_016 PRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLS
       420       430       440       450       460       470       

             530       540       550        560       570       580
pF1KE0 YNKLYHVPSYLPKSLLHLVLLGNQIERIP-GYVFGHMEPGLEYLYLSFNKLADDGMDRVS
        :.:. .:  ::...  : .  :..  .  : . :  .  :. :::. :.: . ..   .
XP_016 GNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ--LRELYLTSNRLRSRALGPRA
       480       490       500       510         520       530     

              590       600       610       620       630       640
pF1KE0 FYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAF
       .    : :. : .  :.:  :: :. :  .:..: :.::::  :   ..... :      
XP_016 WVDLAH-LQLLDIAGNQLTEIPEGLPE--SLEYLYLQNNKISAVPANAFDSTPNLKGIFL
         540        550       560         570       580       590  

                                                                   
pF1KE0 PLW                                                         
                                                                   
XP_016 RFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR
            600       610       620       630       640       650  




643 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 08:30:30 2016 done: Fri Nov  4 08:30:32 2016
 Total Scan time: 12.270 Total Display time:  0.090

Function used was FASTA [36.3.4 Apr, 2011]
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