Result of FASTA (omim) for pF1KB6985
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6985, 219 aa
  1>>>pF1KB6985 219 - 219 aa - 219 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.5224+/-0.00034; mu= 10.7592+/- 0.021
 mean_var=160.6866+/-32.030, 0's: 0 Z-trim(119.4): 20  B-trim: 695 in 1/56
 Lambda= 0.101178
 statistics sampled from 33456 (33478) to 33456 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.393), width:  16
 Scan time:  5.820

The best scores are:                                      opt bits E(85289)
NP_057494 (OMIM: 610900) charged multivesicular bo ( 219) 1406 216.3 3.2e-56
NP_001182465 (OMIM: 610900) charged multivesicular ( 171) 1057 165.2   6e-41
NP_054888 (OMIM: 610051) charged multivesicular bo ( 265)  264 49.7 5.6e-06
NP_789782 (OMIM: 605387,610897) charged multivesic ( 224)  245 46.8 3.4e-05
NP_689497 (OMIM: 610899) charged multivesicular bo ( 233)  207 41.3  0.0016
NP_078867 (OMIM: 610901) charged multivesicular bo ( 201)  193 39.2  0.0061


>>NP_057494 (OMIM: 610900) charged multivesicular body p  (219 aa)
 initn: 1406 init1: 1406 opt: 1406  Z-score: 1130.2  bits: 216.3 E(85289): 3.2e-56
Smith-Waterman score: 1406; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:1-219)

               10        20        30        40        50        60
pF1KB6 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS
              130       140       150       160       170       180

              190       200       210         
pF1KB6 SYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS
       :::::::::::::::::::::::::::::::::::::::
NP_057 SYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS
              190       200       210         

>>NP_001182465 (OMIM: 610900) charged multivesicular bod  (171 aa)
 initn: 1057 init1: 1057 opt: 1057  Z-score: 856.2  bits: 165.2 E(85289): 6e-41
Smith-Waterman score: 1057; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165)

               10        20        30        40        50        60
pF1KB6 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDS
       :::::::::::::::::::::::::::::::::::::::::::::               
NP_001 KQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAGWSSGG         
              130       140       150       160       170          

              190       200       210         
pF1KB6 SYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS

>>NP_054888 (OMIM: 610051) charged multivesicular body p  (265 aa)
 initn: 236 init1: 156 opt: 264  Z-score: 228.4  bits: 49.7 E(85289): 5.6e-06
Smith-Waterman score: 264; 28.9% identity (64.0% similar) in 225 aa overlap (1-216:47-260)

                                             10        20        30
pF1KB6                               MNRLFGKAKPKAPPPSLTDCIGTVDSRAES
                                     ..:::::.: :   :.  . :  .    . 
NP_054 VMRHHPPRSKAEVWRTLRGGGGRGELAMSGLGRLFGKGK-KEKGPTPEEAIQKLKETEKI
         20        30        40        50         60        70     

               40        50        60        70        80        90
pF1KB6 IDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNME
       . ::   :.    : .....  ..  .::  :. ::..:..:. .:::   ::: . .. 
NP_054 LIKKQEFLEQ---KIQQELQTAKKYGTKN--KRAALQALRRKKRFEQQ---LAQTDGTLS
          80           90       100         110          120       

              100          110       120       130       140       
pF1KB6 QANYTIQSLKDTKTTVDA---MKLGVKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQE
         ..  ...... :....   :.:... :::::... ::....:. .. ...: :..:..
NP_054 TLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTDITEQQEVAQQISD
       130       140       150       160       170       180       

       150        160       170       180           190        200 
pF1KB6 ALSRSYGT-PELDEDDLEAELDALGDELLADEDSSYLDE----AASAPAIPEG-VPTDTK
       :.:: .:   ..:::.:  ::. : .: ::.:  .  :.    ... :..:   .:.   
NP_054 AISRPMGFGDDVDEDELLEELEELEQEELAQELLNVGDKEEEPSVKLPSVPSTHLPAGPA
       190       200       210       220       230       240       

             210           
pF1KB6 NKDGVLVDEFGLPQIPAS  
        :  :  :: .: :.     
NP_054 PK--VDEDEEALKQLAEWVS
         250       260     

>>NP_789782 (OMIM: 605387,610897) charged multivesicular  (224 aa)
 initn: 257 init1: 142 opt: 245  Z-score: 214.2  bits: 46.8 E(85289): 3.4e-05
Smith-Waterman score: 245; 29.7% identity (63.2% similar) in 212 aa overlap (3-203:6-206)

                  10          20        30        40        50     
pF1KB6    MNRLFGKAKPKAPP--PSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREG
            .::: .  ::    :.  . :  . .  : ..::   :.    : ....   .. 
NP_789 MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEK---KIEQELTAAKKH
               10        20        30        40           50       

          60        70        80        90       100       110     
pF1KB6 PAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMK-LG--
        .::  :. ::..::.:. ::.:   ::: . ..   ..  ..:....:.....: .:  
NP_789 GTKN--KRAALQALKRKKRYEKQ---LAQIDGTLSTIEFQREALENANTNTEVLKNMGYA
        60          70           80        90       100       110  

            120       130       140       150        160       170 
pF1KB6 VKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGT-PELDEDDLEAELDALG
       .: :: :. .. ::....:.... :..: :.::. :.:.  :   :.:::.: :::. : 
NP_789 AKAMKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELE
            120       130       140       150       160       170  

             180           190        200       210           
pF1KB6 DELLADEDSSYLD----EAASAPAIPE-GVPTDTKNKDGVLVDEFGLPQIPAS  
       .: :   :.. :.    :..  : .:  ..:.   .:                  
NP_789 QEEL---DKNLLEISGPETVPLPNVPSIALPSKPAKKKEEEDDDMKELENWAGSM
               180       190       200       210       220    

>>NP_689497 (OMIM: 610899) charged multivesicular body p  (233 aa)
 initn: 125 init1:  85 opt: 207  Z-score: 184.1  bits: 41.3 E(85289): 0.0016
Smith-Waterman score: 207; 25.2% identity (64.1% similar) in 206 aa overlap (6-206:12-203)

                     10        20        30        40        50    
pF1KB6       MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMRE
                  :..: .: : :  . .  .    : . ::   :. ..   . .:   ..
NP_689 MSKLGKFFKGGGSSKSRAAP-SPQEALVRLRETEEMLGKKQEYLENRI---QREIALAKK
               10        20         30        40           50      

           60        70        80        90       100       110    
pF1KB6 GPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMK-LG-
         ..:  :. ::..::.:. .:.:   :.: . ..   ..  ..:....:...... .: 
NP_689 HGTQN--KRAALQALKRKKRFEKQ---LTQIDGTLSTIEFQREALENSHTNTEVLRNMGF
         60          70           80        90       100       110 

             120       130       140       150        160       170
pF1KB6 -VKEMKKAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGT-PELDEDDLEAELDAL
        .: ::...... ...:.::.... .... :.::.::.:.  :   ..:::.: :::. :
NP_689 AAKAMKSVHENMDLNKIDDLMQEITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEEL
             120       130       140       150       160       170 

              180       190        200       210                   
pF1KB6 GDELLADEDSSYLDEAASAPAIPEG-VPTDTKNKDGVLVDEFGLPQIPAS          
        .: :  . ..        : .: . .:.. . : :.                       
NP_689 EQEELNKKMTN-----IRLPNVPSSSLPAQPNRKPGMSSTARRSRAASSQRAEEEDDDIK
             180            190       200       210       220      

NP_689 QLAAWAT
        230   

>>NP_078867 (OMIM: 610901) charged multivesicular body p  (201 aa)
 initn: 116 init1:  46 opt: 193  Z-score: 173.8  bits: 39.2 E(85289): 0.0061
Smith-Waterman score: 194; 24.5% identity (57.5% similar) in 212 aa overlap (1-208:1-198)

               10        20        30        40        50          
pF1KB6 MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKM-REGPAKN
       :. :::. : ..        :  . .. ... .  .:.  .: . .   ... :.:    
NP_078 MGNLFGRKK-QSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGR---
                10        20        30        40        50         

      60        70        80        90       100       110         
pF1KB6 MVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKA
         :..:  .::.::. ::  :   .:  ..:    .:.  .    .......: . ..: 
NP_078 --KERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKM
           60        70        80        90       100       110    

     120       130       140       150       160       170         
pF1KB6 YKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELDALGDELLADED
       .. ..:...: . :. .. .:   .:.: :. :. : : ::: .  ::.:. .: .    
NP_078 HQVMSIEEVERILDETQEAVEYQRQIDELLAGSF-TQE-DEDAILEELSAITQEQIE---
          120       130       140        150        160            

     180       190          200       210         
pF1KB6 SSYLDEAASAP---AIPEGVPTDTKNKDGVLVDEFGLPQIPAS
          : :. : :    :::.::. .. ... ::           
NP_078 ---LPEVPSEPLPEKIPENVPVKARPRQAELVAAS        
        170       180       190       200         




219 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:24:05 2016 done: Fri Nov  4 10:24:06 2016
 Total Scan time:  5.820 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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