Result of FASTA (omim) for pF1KB6963
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6963, 214 aa
  1>>>pF1KB6963 214 - 214 aa - 214 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.7256+/-0.000518; mu= -3.0523+/- 0.031
 mean_var=519.0368+/-113.288, 0's: 0 Z-trim(118.2): 42  B-trim: 446 in 2/56
 Lambda= 0.056296
 statistics sampled from 30846 (30889) to 30846 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.362), width:  16
 Scan time:  4.590

The best scores are:                                      opt bits E(85289)
NP_036515 (OMIM: 610180) osteoclast-stimulating fa ( 214) 1443 131.4 1.1e-30
XP_006717116 (OMIM: 610180) PREDICTED: osteoclast- ( 217) 1427 130.1 2.7e-30
XP_011516826 (OMIM: 610180) PREDICTED: osteoclast- ( 188) 1253 115.9 4.4e-26
XP_006717118 (OMIM: 610180) PREDICTED: osteoclast- ( 171) 1144 107.0   2e-23
XP_016870111 (OMIM: 610180) PREDICTED: osteoclast- ( 181) 1132 106.0   4e-23
XP_011516827 (OMIM: 610180) PREDICTED: osteoclast- ( 184) 1116 104.8 9.8e-23


>>NP_036515 (OMIM: 610180) osteoclast-stimulating factor  (214 aa)
 initn: 1443 init1: 1443 opt: 1443  Z-score: 672.1  bits: 131.4 E(85289): 1.1e-30
Smith-Waterman score: 1443; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214)

               10        20        30        40        50        60
pF1KB6 MSKPPPKPVKPGQVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MSKPPPKPVKPGQVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 IPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 IVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMA
              130       140       150       160       170       180

              190       200       210    
pF1KB6 TNAACASLLKKKQGTDAVRTLSNAEDYLDDEDSD
       ::::::::::::::::::::::::::::::::::
NP_036 TNAACASLLKKKQGTDAVRTLSNAEDYLDDEDSD
              190       200       210    

>>XP_006717116 (OMIM: 610180) PREDICTED: osteoclast-stim  (217 aa)
 initn: 1376 init1: 1376 opt: 1427  Z-score: 665.0  bits: 130.1 E(85289): 2.7e-30
Smith-Waterman score: 1427; 98.6% identity (98.6% similar) in 217 aa overlap (1-214:1-217)

               10           20        30        40        50       
pF1KB6 MSKPPPKPVKPG---QVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGR
       ::::::::::::   :::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSKPPPKPVKPGEGGQVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGR
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB6 TGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGG
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB6 HKDIVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HKDIVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAF
              130       140       150       160       170       180

       180       190       200       210    
pF1KB6 DMATNAACASLLKKKQGTDAVRTLSNAEDYLDDEDSD
       :::::::::::::::::::::::::::::::::::::
XP_006 DMATNAACASLLKKKQGTDAVRTLSNAEDYLDDEDSD
              190       200       210       

>>XP_011516826 (OMIM: 610180) PREDICTED: osteoclast-stim  (188 aa)
 initn: 1253 init1: 1253 opt: 1253  Z-score: 589.2  bits: 115.9 E(85289): 4.4e-26
Smith-Waterman score: 1253; 100.0% identity (100.0% similar) in 187 aa overlap (28-214:2-188)

               10        20        30        40        50        60
pF1KB6 MSKPPPKPVKPGQVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGL
                                  :::::::::::::::::::::::::::::::::
XP_011                           MPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGL
                                         10        20        30    

               70        80        90       100       110       120
pF1KB6 IPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKD
           40        50        60        70        80        90    

              130       140       150       160       170       180
pF1KB6 IVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMA
          100       110       120       130       140       150    

              190       200       210    
pF1KB6 TNAACASLLKKKQGTDAVRTLSNAEDYLDDEDSD
       ::::::::::::::::::::::::::::::::::
XP_011 TNAACASLLKKKQGTDAVRTLSNAEDYLDDEDSD
          160       170       180        

>>XP_006717118 (OMIM: 610180) PREDICTED: osteoclast-stim  (171 aa)
 initn: 1144 init1: 1144 opt: 1144  Z-score: 541.7  bits: 107.0 E(85289): 2e-23
Smith-Waterman score: 1144; 100.0% identity (100.0% similar) in 171 aa overlap (44-214:1-171)

            20        30        40        50        60        70   
pF1KB6 VKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGLIPSNYVAEQAESI
                                     ::::::::::::::::::::::::::::::
XP_006                               MSDTNWWKGTSKGRTGLIPSNYVAEQAESI
                                             10        20        30

            80        90       100       110       120       130   
pF1KB6 DNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIEL
               40        50        60        70        80        90

           140       150       160       170       180       190   
pF1KB6 NQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMATNAACASLLKKKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMATNAACASLLKKKQ
              100       110       120       130       140       150

           200       210    
pF1KB6 GTDAVRTLSNAEDYLDDEDSD
       :::::::::::::::::::::
XP_006 GTDAVRTLSNAEDYLDDEDSD
              160       170 

>>XP_016870111 (OMIM: 610180) PREDICTED: osteoclast-stim  (181 aa)
 initn: 1176 init1: 1119 opt: 1132  Z-score: 536.2  bits: 106.0 E(85289): 4e-23
Smith-Waterman score: 1161; 84.6% identity (84.6% similar) in 214 aa overlap (1-214:1-181)

               10        20        30        40        50        60
pF1KB6 MSKPPPKPVKPGQVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSKPPPKPVKPGQVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGRTGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 IPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 IVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMA
       ::::::::::::::::::::::::::::::::::::::::::                  
XP_016 IVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAK------------------
              130       140       150       160                    

              190       200       210    
pF1KB6 TNAACASLLKKKQGTDAVRTLSNAEDYLDDEDSD
                      :::::::::::::::::::
XP_016 ---------------DAVRTLSNAEDYLDDEDSD
                           170       180 

>>XP_011516827 (OMIM: 610180) PREDICTED: osteoclast-stim  (184 aa)
 initn: 1183 init1: 1045 opt: 1116  Z-score: 529.1  bits: 104.8 E(85289): 9.8e-23
Smith-Waterman score: 1145; 83.4% identity (83.4% similar) in 217 aa overlap (1-214:1-184)

               10           20        30        40        50       
pF1KB6 MSKPPPKPVKPG---QVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGR
       ::::::::::::   :::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSKPPPKPVKPGEGGQVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTSKGR
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB6 TGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGG
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB6 HKDIVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAF
       :::::::::::::::::::::::::::::::::::::::::::::               
XP_011 HKDIVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAK---------------
              130       140       150       160                    

       180       190       200       210    
pF1KB6 DMATNAACASLLKKKQGTDAVRTLSNAEDYLDDEDSD
                         :::::::::::::::::::
XP_011 ------------------DAVRTLSNAEDYLDDEDSD
                           170       180    




214 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 11:15:29 2016 done: Fri Nov  4 11:15:30 2016
 Total Scan time:  4.590 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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