Result of FASTA (omim) for pF1KB6911
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6911, 205 aa
  1>>>pF1KB6911 205 - 205 aa - 205 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7434+/-0.000401; mu= 16.4221+/- 0.025
 mean_var=59.1563+/-12.127, 0's: 0 Z-trim(110.3): 31  B-trim: 705 in 1/51
 Lambda= 0.166753
 statistics sampled from 18585 (18613) to 18585 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.596), E-opt: 0.2 (0.218), width:  16
 Scan time:  5.320

The best scores are:                                      opt bits E(85289)
NP_002786 (OMIM: 602176) proteasome subunit beta t ( 205) 1367 337.2 1.1e-92
NP_002784 (OMIM: 602017) proteasome subunit beta t ( 241)  287 77.5   2e-14
NP_002791 (OMIM: 177045) proteasome subunit beta t ( 219)  220 61.3 1.3e-09
NP_002789 (OMIM: 600307) proteasome subunit beta t ( 239)  213 59.7 4.6e-09
NP_004150 (OMIM: 177046,256040) proteasome subunit ( 272)  188 53.7 3.3e-07
NP_683720 (OMIM: 177046,256040) proteasome subunit ( 276)  188 53.7 3.3e-07
NP_002788 (OMIM: 600306) proteasome subunit beta t ( 263)  184 52.7 6.3e-07
NP_001257410 (OMIM: 600307) proteasome subunit bet ( 213)  177 51.0 1.7e-06
NP_002785 (OMIM: 602175) proteasome subunit beta t ( 201)  154 45.4 7.5e-05
NP_001093250 (OMIM: 611137) proteasome subunit bet ( 300)  155 45.8 8.8e-05
NP_002790 (OMIM: 604030) proteasome subunit beta t ( 277)  154 45.5 9.7e-05
NP_001138404 (OMIM: 600306) proteasome subunit bet ( 203)  131 39.9  0.0035
NP_001124197 (OMIM: 600306) proteasome subunit bet ( 160)  128 39.1  0.0048
NP_001186708 (OMIM: 602175) proteasome subunit bet ( 176)  127 38.9  0.0061
XP_005267928 (OMIM: 600306) PREDICTED: proteasome  ( 169)  125 38.4  0.0083


>>NP_002786 (OMIM: 602176) proteasome subunit beta type-  (205 aa)
 initn: 1367 init1: 1367 opt: 1367  Z-score: 1785.0  bits: 337.2 E(85289): 1.1e-92
Smith-Waterman score: 1367; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205)

               10        20        30        40        50        60
pF1KB6 MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 QTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 ICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAV
              130       140       150       160       170       180

              190       200     
pF1KB6 SGMGVIVHIIEKDKITTRTLKARMD
       :::::::::::::::::::::::::
NP_002 SGMGVIVHIIEKDKITTRTLKARMD
              190       200     

>>NP_002784 (OMIM: 602017) proteasome subunit beta type-  (241 aa)
 initn: 224 init1: 224 opt: 287  Z-score: 379.8  bits: 77.5 E(85289): 2e-14
Smith-Waterman score: 287; 25.8% identity (64.1% similar) in 209 aa overlap (6-205:35-241)

                                        10        20        30     
pF1KB6                          MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMV
                                     .:::...:. :.. . .:.: :..   .. 
NP_002 TAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIH
           10        20        30        40        50        60    

          40        50        60        70        80        90     
pF1KB6 TTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLL
       : :  : . . :.  :: .:.  :  :... .. ::..:. .... .   .. .:....:
NP_002 TRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTIL
           70        80        90       100       110       120    

         100       110       120       130       140       150     
pF1KB6 YEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCES-LW
       : .:: :::.  .:.::: .  :  . :.: .:  .  :.: ..:. . ..  . .. . 
NP_002 YSRRFFPYYVYNIIGGLDEEG-KGAVYSFDPVGS-YQRDSFKAGGSASAMLQPLLDNQVG
          130       140        150        160       170       180  

           160       170              180       190       200     
pF1KB6 EPNM-DPDHLFETISQAM-------LNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD
         :: . .:.  ....::       ..:..::. .: .. . :. :. :  .:.. : :
NP_002 FKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD
            190       200       210       220       230       240 

>>NP_002791 (OMIM: 177045) proteasome subunit beta type-  (219 aa)
 initn:  97 init1:  77 opt: 220  Z-score: 293.3  bits: 61.3 E(85289): 1.3e-09
Smith-Waterman score: 220; 27.6% identity (63.2% similar) in 185 aa overlap (6-186:18-193)

                           10        20        30        40        
pF1KB6             MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDR
                        ..: ..::..  . :....: : .    .:.  :.:. :. .:
NP_002 MLRAGAPTGDLPRAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHER
               10        20        30        40        50        60

       50        60        70          80          90       100    
pF1KB6 LYIGLAGLATDVQTVAQRLKFRLNLY--ELKEGRQIKPYTLMS--MVANLLYEKRFGPYY
       .: .:.: :.:.:.::.   ..:.:.  ::.:     : .: .  .: :. :. :     
NP_002 IYCALSGSAADAQAVADMAAYQLELHGIELEE----PPLVLAAANVVRNISYKYRED-LS
               70        80        90           100       110      

          110       120       130       140       150       160    
pF1KB6 TEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLF
       .. ..:: : .       .:   :  .. . :...:. .  .::. .. ..:.:.:..  
NP_002 AHLMVAGWDQREGGQVYGTL---GGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECR
         120       130          140       150       160       170  

          170       180       190       200            
pF1KB6 ETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD       
       .  ..:.  :..::. :: :::                          
NP_002 RFTTDAIALAMSRDGSSG-GVIYLVTITAAGVDHRVILGNELPKFYDE
            180       190        200       210         

>>NP_002789 (OMIM: 600307) proteasome subunit beta type-  (239 aa)
 initn: 202 init1:  99 opt: 213  Z-score: 283.7  bits: 59.7 E(85289): 4.6e-09
Smith-Waterman score: 213; 25.1% identity (63.1% similar) in 179 aa overlap (8-186:34-208)

                                      10        20        30       
pF1KB6                        MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTT
                                     : ..::..  . :...:: :    . ... 
NP_002 TLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANR
            10        20        30        40        50        60   

        40        50        60        70        80        90       
pF1KB6 DFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYE
         .:. :. ::..   .: :.:.:.::. . ..:... .. ..    .:  :.  .. :.
NP_002 VTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYR
            70        80        90       100       110       120   

       100       110       120       130       140       150       
pF1KB6 KRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPN
        :    ..  .::: ::.     . :. . :  :: ..:...:. .  .::. .. .. .
NP_002 YRED-LMAGIIIAGWDPQEGGQ-VYSVPMGGM-MVRQSFAIGGSGSSYIYGYVDATYREG
            130       140        150        160       170       180

       160       170       180       190       200                 
pF1KB6 MDPDHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD            
       :  .. ..  ..:.  :..::. :: :::                               
NP_002 MTKEECLQFTANALALAMERDGSSG-GVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA
              190       200        210       220       230         

>>NP_004150 (OMIM: 177046,256040) proteasome subunit bet  (272 aa)
 initn: 103 init1:  86 opt: 188  Z-score: 250.4  bits: 53.7 E(85289): 3.3e-07
Smith-Waterman score: 188; 23.0% identity (56.7% similar) in 187 aa overlap (7-193:67-250)

                                       10        20        30      
pF1KB6                         MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVT
                                     .: ...:.: .. :  :.: : .  . . .
NP_004 VSSGCPGLEPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISA
         40        50        60        70        80        90      

         40        50        60        70        80        90      
pF1KB6 TDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLY
          .:.. ..  :   ..: :.: :   . :  .  :: :..:..:.  .  ....:.. 
NP_004 LRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMC
        100       110       120       130       140       150      

        100       110       120       130       140       150      
pF1KB6 EKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEP
       . :        .: : : :   : .  .:  :  . . ..  .:.     ::. .: ..:
NP_004 QYRGMGLSMGSMICGWDKKG--PGLYYVDEHGTRL-SGNMFSTGSGNTYAYGVMDSGYRP
        160       170         180        190       200       210   

        160       170       180       190       200               
pF1KB6 NMDPDHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD          
       :..:.. ..   .:.  :. ::. ::  : .. ...:                      
NP_004 NLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ
           220       230       240       250       260       270  

>>NP_683720 (OMIM: 177046,256040) proteasome subunit bet  (276 aa)
 initn:  86 init1:  86 opt: 188  Z-score: 250.3  bits: 53.7 E(85289): 3.3e-07
Smith-Waterman score: 188; 23.0% identity (56.7% similar) in 187 aa overlap (7-193:71-254)

                                       10        20        30      
pF1KB6                         MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVT
                                     .: ...:.: .. :  :.: : .  . . .
NP_683 ELALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISA
               50        60        70        80        90       100

         40        50        60        70        80        90      
pF1KB6 TDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLY
          .:.. ..  :   ..: :.: :   . :  .  :: :..:..:.  .  ....:.. 
NP_683 LRVNKVIEINPYLLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMC
              110       120       130       140       150       160

        100       110       120       130       140       150      
pF1KB6 EKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEP
       . :        .: : : :   : .  .:  :  . . ..  .:.     ::. .: ..:
NP_683 QYRGMGLSMGSMICGWDKKG--PGLYYVDEHGTRL-SGNMFSTGSGNTYAYGVMDSGYRP
              170       180         190        200       210       

        160       170       180       190       200               
pF1KB6 NMDPDHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD          
       :..:.. ..   .:.  :. ::. ::  : .. ...:                      
NP_683 NLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVESTDVSDLLHQYREANQ
       220       230       240       250       260       270      

>>NP_002788 (OMIM: 600306) proteasome subunit beta type-  (263 aa)
 initn: 151 init1:  95 opt: 184  Z-score: 245.4  bits: 52.7 E(85289): 6.3e-07
Smith-Waterman score: 184; 23.0% identity (56.1% similar) in 187 aa overlap (7-193:58-241)

                                       10        20        30      
pF1KB6                         MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVT
                                     .: ...:.: .. : .::: :    : ...
NP_002 LDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIAS
        30        40        50        60        70        80       

         40        50        60        70        80        90      
pF1KB6 TDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLY
          .:.. ..  :   .:: :.: .   . :  .  .:::.. ..:.  .  ...::..:
NP_002 QTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVY
        90       100       110       120       130       140       

        100       110       120       130       140       150      
pF1KB6 EKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEP
       . .        .: : : .   : .  .:  :  .    : : :. .   ::. .  .  
NP_002 QYKGMGLSMGTMICGWDKRG--PGLYYVDSEGNRISGATFSV-GSGSVYAYGVMDRGYSY
       150       160         170       180        190       200    

        160       170       180       190       200               
pF1KB6 NMDPDHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD          
       ... .. ..   .:. .:. ::: :: .: .. ...:                      
NP_002 DLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
          210       220       230       240       250       260   

>>NP_001257410 (OMIM: 600307) proteasome subunit beta ty  (213 aa)
 initn: 172 init1:  99 opt: 177  Z-score: 237.6  bits: 51.0 E(85289): 1.7e-06
Smith-Waterman score: 177; 22.4% identity (62.4% similar) in 165 aa overlap (8-172:34-195)

                                      10        20        30       
pF1KB6                        MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTT
                                     : ..::..  . :...:: :    . ... 
NP_001 TLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANR
            10        20        30        40        50        60   

        40        50        60        70        80        90       
pF1KB6 DFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYE
         .:. :. ::..   .: :.:.:.::. . ..:... .. ..    .:  :.  .. :.
NP_001 VTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYR
            70        80        90       100       110       120   

       100       110       120       130       140       150       
pF1KB6 KRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPN
        :    ..  .::: ::.     . :. . :  :: ..:...:. .  .::. .. .. .
NP_001 YRED-LMAGIIIAGWDPQEGGQ-VYSVPM-GGMMVRQSFAIGGSGSSYIYGYVDATYREG
            130       140        150        160       170       180

       160       170       180       190       200     
pF1KB6 MDPDHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD
       :  .. ..  ..:..                                 
NP_001 MTKEECLQFTANAFFFYPQLSLWPWSGMAPVEE               
              190       200       210                  

>>NP_002785 (OMIM: 602175) proteasome subunit beta type-  (201 aa)
 initn:  39 init1:  39 opt: 154  Z-score: 208.0  bits: 45.4 E(85289): 7.5e-05
Smith-Waterman score: 154; 19.3% identity (57.2% similar) in 187 aa overlap (11-195:4-188)

               10        20        30        40        50        60
pF1KB6 MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDV
                 .....: . : .:.::  . .  ..  : .:.: :.... .  .: : :.
NP_002        MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDT
                      10        20        30        40        50   

               70        80        90         100       110        
pF1KB6 QTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYE--KRFGPYYTEPVIAGLDPKTFK
          :. ..  ..::....: ...: .  ...   : .  .   ::... ..:: : .   
NP_002 VQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHE-G
            60        70        80        90       100       110   

      120       130       140       150       160       170        
pF1KB6 PFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRD
       : .  .: ..  ..   :.. :  :    .. .  . :... ..  : . . . .   : 
NP_002 PALYYMDYLAA-LAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRF
            120        130       140       150       160       170 

      180       190       200        
pF1KB6 AVSGMGVIVHIIEKDKITTRTLKARMD   
        ..     :.::.:. :             
NP_002 ILNLPTFSVRIIDKNGIHDLDNISFPKQGS
             180       190       200 

>>NP_001093250 (OMIM: 611137) proteasome subunit beta ty  (300 aa)
 initn:  82 init1:  57 opt: 155  Z-score: 206.9  bits: 45.8 E(85289): 8.8e-05
Smith-Waterman score: 155; 23.1% identity (53.8% similar) in 186 aa overlap (7-191:48-230)

                                       10        20        30      
pF1KB6                         MSIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVT
                                     .: ...:.. .. :  ::: : .  . .. 
NP_001 SPHLPRAGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVAC
        20        30        40        50        60        70       

         40        50        60        70        80        90      
pF1KB6 TDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLY
           :..:. ..:    .: ..:  :  . :. .: : ::.::.  .  .  .... .. 
NP_001 PASCKVIPVHQHLLGTTSGTSADCATWYRVLQRELRLRELREGQLPSVASAAKLLSAMMS
        80        90       100       110       120       130       

        100       110       120       130       140       150      
pF1KB6 EKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEP
       . :     .  .. : : .  . :    :  :  .  : : : :. .   ::. .  .. 
NP_001 QYRGLDLCVATALCGWDRSGPELFYVYSD--GTRLQGDIFSV-GSGSPYAYGVLDRGYRY
       140       150       160         170        180       190    

        160       170       180        190       200               
pF1KB6 NMDPDHLFETISQAMLNAVDRDAVSGMGV-IVHIIEKDKITTRTLKARMD          
       .:. .. .     :. .:. ::: :: .: . :. :                        
NP_001 DMSTQEAYALARCAVAHATHRDAYSGGSVDLFHVRESGWEHVSRSDACVLYVELQKLLEP
          200       210       220       230       240       250    

NP_001 EPEEDASHAHPEPATAHRAAEDRELSVGPGEVTPGDSRMPAGTETV
          260       270       280       290       300




205 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 13:00:35 2016 done: Fri Nov  4 13:00:36 2016
 Total Scan time:  5.320 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com