Result of FASTA (omim) for pF1KB6840
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6840, 191 aa
  1>>>pF1KB6840 191 - 191 aa - 191 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.8690+/-0.000366; mu= 15.1237+/- 0.022
 mean_var=62.6865+/-13.057, 0's: 0 Z-trim(112.7): 23  B-trim: 911 in 1/52
 Lambda= 0.161990
 statistics sampled from 21736 (21754) to 21736 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.255), width:  16
 Scan time:  5.340

The best scores are:                                      opt bits E(85289)
NP_004128 (OMIM: 603951,608622) calcium-activated  ( 191) 1272 305.7 2.9e-83
NP_005823 (OMIM: 605214) calcium-activated potassi ( 235)  534 133.3 2.8e-31
NP_852006 (OMIM: 605214) calcium-activated potassi ( 235)  534 133.3 2.8e-31
NP_001265840 (OMIM: 605214) calcium-activated pota ( 235)  534 133.3 2.8e-31
XP_011510627 (OMIM: 605214) PREDICTED: calcium-act ( 235)  534 133.3 2.8e-31
NP_741980 (OMIM: 605222) calcium-activated potassi ( 257)  235 63.5 3.3e-10
NP_741981 (OMIM: 605222) calcium-activated potassi ( 275)  235 63.5 3.5e-10
NP_741979 (OMIM: 605222) calcium-activated potassi ( 277)  235 63.5 3.5e-10
NP_055222 (OMIM: 605222) calcium-activated potassi ( 279)  235 63.5 3.5e-10
NP_055320 (OMIM: 605223) calcium-activated potassi ( 210)  167 47.5 1.7e-05
NP_001157149 (OMIM: 605222) calcium-activated pota ( 173)  127 38.1  0.0096


>>NP_004128 (OMIM: 603951,608622) calcium-activated pota  (191 aa)
 initn: 1272 init1: 1272 opt: 1272  Z-score: 1615.8  bits: 305.7 E(85289): 2.9e-83
Smith-Waterman score: 1272; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191)

               10        20        30        40        50        60
pF1KB6 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 RDQEELKGKKVPQYPCLWVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RDQEELKGKKVPQYPCLWVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 EKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKS
              130       140       150       160       170       180

              190 
pF1KB6 NQYLSILAAQK
       :::::::::::
NP_004 NQYLSILAAQK
              190 

>>NP_005823 (OMIM: 605214) calcium-activated potassium c  (235 aa)
 initn: 532 init1: 339 opt: 534  Z-score: 682.4  bits: 133.3 E(85289): 2.8e-31
Smith-Waterman score: 534; 43.5% identity (73.1% similar) in 193 aa overlap (3-187:34-226)

                                           10        20        30  
pF1KB6                             MVKKLVMAQKRGETRALCLGVTMVVCAVITYY
                                     .: : : : :: ::. ::..:.::... :.
NP_005 WTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYF
            10        20        30        40        50        60   

             40        50        60              70          80    
pF1KB6 ILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELK---GK---KVPQYPCL--WVNVSAA
       .:  :.:  :..::::.::.: :....: .  . .   :    :. :::::  .::....
NP_005 LLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSS
            70        80        90       100       110       120   

           90       100       110       120       130       140    
pF1KB6 GRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNET
       :.  .:::::.:   ::.:::::    :.. . . :. :  .:.. : : :.: :.::. 
NP_005 GEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQK
           130       140       150       160       170       180   

          150       160       170       180       190      
pF1KB6 SVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK     
       ::.. .::. ..:. :::::: ...::. :.:::: .::::.:         
NP_005 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
           190       200       210       220       230     

>>NP_852006 (OMIM: 605214) calcium-activated potassium c  (235 aa)
 initn: 532 init1: 339 opt: 534  Z-score: 682.4  bits: 133.3 E(85289): 2.8e-31
Smith-Waterman score: 534; 43.5% identity (73.1% similar) in 193 aa overlap (3-187:34-226)

                                           10        20        30  
pF1KB6                             MVKKLVMAQKRGETRALCLGVTMVVCAVITYY
                                     .: : : : :: ::. ::..:.::... :.
NP_852 WTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYF
            10        20        30        40        50        60   

             40        50        60              70          80    
pF1KB6 ILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELK---GK---KVPQYPCL--WVNVSAA
       .:  :.:  :..::::.::.: :....: .  . .   :    :. :::::  .::....
NP_852 LLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSS
            70        80        90       100       110       120   

           90       100       110       120       130       140    
pF1KB6 GRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNET
       :.  .:::::.:   ::.:::::    :.. . . :. :  .:.. : : :.: :.::. 
NP_852 GEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQK
           130       140       150       160       170       180   

          150       160       170       180       190      
pF1KB6 SVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK     
       ::.. .::. ..:. :::::: ...::. :.:::: .::::.:         
NP_852 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
           190       200       210       220       230     

>>NP_001265840 (OMIM: 605214) calcium-activated potassiu  (235 aa)
 initn: 532 init1: 339 opt: 534  Z-score: 682.4  bits: 133.3 E(85289): 2.8e-31
Smith-Waterman score: 534; 43.5% identity (73.1% similar) in 193 aa overlap (3-187:34-226)

                                           10        20        30  
pF1KB6                             MVKKLVMAQKRGETRALCLGVTMVVCAVITYY
                                     .: : : : :: ::. ::..:.::... :.
NP_001 WTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYF
            10        20        30        40        50        60   

             40        50        60              70          80    
pF1KB6 ILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELK---GK---KVPQYPCL--WVNVSAA
       .:  :.:  :..::::.::.: :....: .  . .   :    :. :::::  .::....
NP_001 LLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSS
            70        80        90       100       110       120   

           90       100       110       120       130       140    
pF1KB6 GRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNET
       :.  .:::::.:   ::.:::::    :.. . . :. :  .:.. : : :.: :.::. 
NP_001 GEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQK
           130       140       150       160       170       180   

          150       160       170       180       190      
pF1KB6 SVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK     
       ::.. .::. ..:. :::::: ...::. :.:::: .::::.:         
NP_001 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
           190       200       210       220       230     

>>XP_011510627 (OMIM: 605214) PREDICTED: calcium-activat  (235 aa)
 initn: 532 init1: 339 opt: 534  Z-score: 682.4  bits: 133.3 E(85289): 2.8e-31
Smith-Waterman score: 534; 43.5% identity (73.1% similar) in 193 aa overlap (3-187:34-226)

                                           10        20        30  
pF1KB6                             MVKKLVMAQKRGETRALCLGVTMVVCAVITYY
                                     .: : : : :: ::. ::..:.::... :.
XP_011 WTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYF
            10        20        30        40        50        60   

             40        50        60              70          80    
pF1KB6 ILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELK---GK---KVPQYPCL--WVNVSAA
       .:  :.:  :..::::.::.: :....: .  . .   :    :. :::::  .::....
XP_011 LLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSS
            70        80        90       100       110       120   

           90       100       110       120       130       140    
pF1KB6 GRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNET
       :.  .:::::.:   ::.:::::    :.. . . :. :  .:.. : : :.: :.::. 
XP_011 GEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQK
           130       140       150       160       170       180   

          150       160       170       180       190      
pF1KB6 SVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK     
       ::.. .::. ..:. :::::: ...::. :.:::: .::::.:         
XP_011 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
           190       200       210       220       230     

>>NP_741980 (OMIM: 605222) calcium-activated potassium c  (257 aa)
 initn: 324 init1: 153 opt: 235  Z-score: 304.2  bits: 63.5 E(85289): 3.3e-10
Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:32-218)

                                  10        20        30        40 
pF1KB6                    MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL
                                     :: ::. :: .:.  .:. ...: ::.:  
NP_741 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
              10        20        30        40        50        60 

              50        60               70          80        90  
pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH
       .. :.  .:: :  :.:.: :.         .. .   .::::  .::.:  :. :.:..
NP_741 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
              70        80        90       100       110       120 

            100       110       120       130         140       150
pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR
       .:.. . : .: : :   .. .    ..  ..  :....   : :: .: ..  .:.. .
NP_741 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
             130       140       150       160       170       180 

              160       170       180       190                    
pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK                   
        :  .:..  ::::.. : :: ::..::. .:.::.:                       
NP_741 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
             190       200       210       220       230       240 

NP_741 FKLCIMRRSKGRAEKS
             250       

>>NP_741981 (OMIM: 605222) calcium-activated potassium c  (275 aa)
 initn: 324 init1: 153 opt: 235  Z-score: 303.8  bits: 63.5 E(85289): 3.5e-10
Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:50-236)

                                  10        20        30        40 
pF1KB6                    MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL
                                     :: ::. :: .:.  .:. ...: ::.:  
NP_741 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
      20        30        40        50        60        70         

              50        60               70          80        90  
pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH
       .. :.  .:: :  :.:.: :.         .. .   .::::  .::.:  :. :.:..
NP_741 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
      80        90       100       110       120       130         

            100       110       120       130         140       150
pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR
       .:.. . : .: : :   .. .    ..  ..  :....   : :: .: ..  .:.. .
NP_741 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
     140       150       160       170       180       190         

              160       170       180       190                    
pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK                   
        :  .:..  ::::.. : :: ::..::. .:.::.:                       
NP_741 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
     200       210       220       230       240       250         

NP_741 FKLCIMRRSKGRAEKS
     260       270     

>>NP_741979 (OMIM: 605222) calcium-activated potassium c  (277 aa)
 initn: 324 init1: 153 opt: 235  Z-score: 303.8  bits: 63.5 E(85289): 3.5e-10
Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:52-238)

                                  10        20        30        40 
pF1KB6                    MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL
                                     :: ::. :: .:.  .:. ...: ::.:  
NP_741 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
              30        40        50        60        70        80 

              50        60               70          80        90  
pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH
       .. :.  .:: :  :.:.: :.         .. .   .::::  .::.:  :. :.:..
NP_741 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
              90       100       110       120       130       140 

            100       110       120       130         140       150
pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR
       .:.. . : .: : :   .. .    ..  ..  :....   : :: .: ..  .:.. .
NP_741 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
             150       160       170       180       190       200 

              160       170       180       190                    
pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK                   
        :  .:..  ::::.. : :: ::..::. .:.::.:                       
NP_741 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
             210       220       230       240       250       260 

NP_741 FKLCIMRRSKGRAEKS
             270       

>>NP_055222 (OMIM: 605222) calcium-activated potassium c  (279 aa)
 initn: 324 init1: 153 opt: 235  Z-score: 303.7  bits: 63.5 E(85289): 3.5e-10
Smith-Waterman score: 318; 31.0% identity (63.1% similar) in 187 aa overlap (12-187:54-240)

                                  10        20        30        40 
pF1KB6                    MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPL
                                     :: ::. :: .:.  .:. ...: ::.:  
NP_055 TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
            30        40        50        60        70        80   

              50        60               70          80        90  
pF1KB6 YQKSVWTQESKCHLIETNIRDQEE-------LKGKKVPQYPCL--WVNVSAAGRWAVLYH
       .. :.  .:: :  :.:.: :.         .. .   .::::  .::.:  :. :.:..
NP_055 FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
            90       100       110       120       130       140   

            100       110       120       130         140       150
pF1KB6 TEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQ--VFYCFSAPRGNETSVLFQR
       .:.. . : .: : :   .. .    ..  ..  :....   : :: .: ..  .:.. .
NP_055 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
           150       160       170       180       190       200   

              160       170       180       190                    
pF1KB6 LYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK                   
        :  .:..  ::::.. : :: ::..::. .:.::.:                       
NP_055 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
           210       220       230       240       250       260   

NP_055 FKLCIMRRSKGRAEKS
           270         

>>NP_055320 (OMIM: 605223) calcium-activated potassium c  (210 aa)
 initn: 125 init1:  70 opt: 167  Z-score: 219.6  bits: 47.5 E(85289): 1.7e-05
Smith-Waterman score: 191; 22.2% identity (54.7% similar) in 203 aa overlap (1-188:1-201)

                10        20        30        40        50         
pF1KB6 MVK-KLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLI---
       :.: ....   ..: ... ::. ... .:.. .:.    :    ... . :..: ..   
NP_055 MAKLRVAYEYTEAEDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQATEANCTVLSVQ
               10        20        30        40        50        60

               60        70          80        90       100        
pF1KB6 ------ETNIRDQEELKGKKVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPG
             : ..    . .: .  ::::.  .:: : ..  :.:.  :     : .::::: 
NP_055 QIGEVFECTFTCGADCRGTS--QYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPP
               70        80          90       100       110        

      110       120       130          140       150       160     
pF1KB6 SVDNYQTARADVEKVRAKFQEQ---QVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPT
          . :    .: . .  ....   : : :.   .    .::..: .   .::  ..:: 
NP_055 CKRENQKNLESVMNWQQYWKDEIGSQPFTCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPL
      120       130       140       150       160       170        

         170       180       190       
pF1KB6 FLLTGGLLIIAMVKSNQYLSILAAQK      
         .. :.::....   . :.. :         
NP_055 VTFVVGVLIVVLTICAKSLAVKAEAMKKRKFS
      180       190       200       210




191 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 14:56:36 2016 done: Fri Nov  4 14:56:37 2016
 Total Scan time:  5.340 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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