Result of FASTA (ccds) for pF1KB6438
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6438, 340 aa
  1>>>pF1KB6438 340 - 340 aa - 340 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8363+/-0.000707; mu= 14.8396+/- 0.043
 mean_var=87.8107+/-17.263, 0's: 0 Z-trim(111.9): 85  B-trim: 74 in 1/51
 Lambda= 0.136868
 statistics sampled from 12655 (12742) to 12655 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.391), width:  16
 Scan time:  2.450

The best scores are:                                      opt bits E(32554)
CCDS43096.1 RASSF1 gene_id:11186|Hs108|chr3        ( 340) 2348 473.0 1.6e-133
CCDS2820.1 RASSF1 gene_id:11186|Hs108|chr3         ( 344) 2320 467.5 7.2e-132
CCDS2821.1 RASSF1 gene_id:11186|Hs108|chr3         ( 270) 1463 298.2 5.2e-81
CCDS2822.1 RASSF1 gene_id:11186|Hs108|chr3         ( 189) 1251 256.2 1.6e-68
CCDS30998.1 RASSF5 gene_id:83593|Hs108|chr1        ( 418)  942 195.4 6.9e-50
CCDS1464.1 RASSF5 gene_id:83593|Hs108|chr1         ( 265)  754 158.2 7.1e-39
CCDS1463.1 RASSF5 gene_id:83593|Hs108|chr1         ( 336)  628 133.4 2.7e-31
CCDS8969.1 RASSF3 gene_id:283349|Hs108|chr12       ( 238)  430 94.2 1.2e-19


>>CCDS43096.1 RASSF1 gene_id:11186|Hs108|chr3             (340 aa)
 initn: 2348 init1: 2348 opt: 2348  Z-score: 2510.8  bits: 473.0 E(32554): 1.6e-133
Smith-Waterman score: 2348; 100.0% identity (100.0% similar) in 340 aa overlap (1-340:1-340)

               10        20        30        40        50        60
pF1KB6 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 THTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRCRALVCLDCCGPRDLGWEPAVERDTNVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 THTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRCRALVCLDCCGPRDLGWEPAVERDTNVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 EPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 EPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 KPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 KFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPE
              250       260       270       280       290       300

              310       320       330       340
pF1KB6 LHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
       ::::::::::::::::::::::::::::::::::::::::
CCDS43 LHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
              310       320       330       340

>>CCDS2820.1 RASSF1 gene_id:11186|Hs108|chr3              (344 aa)
 initn: 1749 init1: 1749 opt: 2320  Z-score: 2480.9  bits: 467.5 E(32554): 7.2e-132
Smith-Waterman score: 2320; 98.5% identity (98.8% similar) in 344 aa overlap (1-340:1-344)

               10        20        30        40        50        60
pF1KB6 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTACNPTRQLVPGRGHRFQPAGPA
               10        20        30        40        50        60

               70        80            90       100       110      
pF1KB6 THTWCDLCGDFIWGVVRKGLQCAH----CKFTCHYRCRALVCLDCCGPRDLGWEPAVERD
       :::::::::::::::::::::::.    ::::::::::::::::::::::::::::::::
CCDS28 THTWCDLCGDFIWGVVRKGLQCARLSADCKFTCHYRCRALVCLDCCGPRDLGWEPAVERD
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KB6 TNVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 TNVDEPVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSV
              130       140       150       160       170       180

        180       190       200       210       220       230      
pF1KB6 PSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 PSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVV
              190       200       210       220       230       240

        240       250       260       270       280       290      
pF1KB6 DDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 DDPRKFALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAF
              250       260       270       280       290       300

        300       310       320       330       340
pF1KB6 SMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
       ::::::::::::::::::::::::::::::::::::::::::::
CCDS28 SMPELHNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
              310       320       330       340    

>>CCDS2821.1 RASSF1 gene_id:11186|Hs108|chr3              (270 aa)
 initn: 1463 init1: 1463 opt: 1463  Z-score: 1567.9  bits: 298.2 E(32554): 5.2e-81
Smith-Waterman score: 1463; 100.0% identity (100.0% similar) in 221 aa overlap (120-340:50-270)

      90       100       110       120       130       140         
pF1KB6 HYRCRALVCLDCCGPRDLGWEPAVERDTNVDEPVEWETPDLSQAEIEQKIKEYNAQINSN
                                     ::::::::::::::::::::::::::::::
CCDS28 GYCSQEDSDSELEQYFTARTSLARRPRRDQDEPVEWETPDLSQAEIEQKIKEYNAQINSN
      20        30        40        50        60        70         

     150       160       170       180       190       200         
pF1KB6 LFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 LFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKD
      80        90       100       110       120       130         

     210       220       230       240       250       260         
pF1KB6 AVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 AVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLR
     140       150       160       170       180       190         

     270       280       290       300       310       320         
pF1KB6 LLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 LLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQK
     200       210       220       230       240       250         

     330       340
pF1KB6 IQEALHACPLG
       :::::::::::
CCDS28 IQEALHACPLG
     260       270

>>CCDS2822.1 RASSF1 gene_id:11186|Hs108|chr3              (189 aa)
 initn: 1251 init1: 1251 opt: 1251  Z-score: 1343.8  bits: 256.2 E(32554): 1.6e-68
Smith-Waterman score: 1251; 100.0% identity (100.0% similar) in 189 aa overlap (152-340:1-189)

             130       140       150       160       170       180 
pF1KB6 PVEWETPDLSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKK
                                     ::::::::::::::::::::::::::::::
CCDS28                               MSLNKDGSYTGFIKVQLKLVRPVSVPSSKK
                                             10        20        30

             190       200       210       220       230       240 
pF1KB6 PPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 PPSLQDARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRK
               40        50        60        70        80        90

             250       260       270       280       290       300 
pF1KB6 FALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS28 FALFERAERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPEL
              100       110       120       130       140       150

             310       320       330       340
pF1KB6 HNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
       :::::::::::::::::::::::::::::::::::::::
CCDS28 HNFLRILQREEEEHLRQILQKYSYCRQKIQEALHACPLG
              160       170       180         

>>CCDS30998.1 RASSF5 gene_id:83593|Hs108|chr1             (418 aa)
 initn: 928 init1: 754 opt: 942  Z-score: 1009.1  bits: 195.4 E(32554): 6.9e-50
Smith-Waterman score: 942; 47.3% identity (71.6% similar) in 338 aa overlap (11-334:81-410)

                                   10        20        30        40
pF1KB6                     MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTAC
                                     : : : :   . : :   :   : .:.   
CCDS30 STAPGAREGRSARRAARGNLEPPPRASRPARPLRP-GLQQRLRRR-PGAPRPRDVRSIFE
               60        70        80         90        100        

                  50            60        70        80        90   
pF1KB6 NPTRQLVP---GRGHRFQ----PAGPATHTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRC
       .:    ::   :.:: :     :.::.   ::::::     :.:..:.:..:::::: .:
CCDS30 QPQDPRVPAERGEGHCFAELVLPGGPG---WCDLCGRE---VLRQALRCTNCKFTCHPEC
      110       120       130          140          150       160  

           100       110              120       130       140      
pF1KB6 RALVCLDCCGPRDLGWE-PAVER------DTNVDEPVEWETPDLSQAEIEQKIKEYNAQI
       :.:. :::   . :. . :. :       . :: .:::      .  ::.:::  ::.. 
CCDS30 RSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQEIKQKIDSYNTRE
            170       180       190       200       210       220  

        150       160       170       180       190       200      
pF1KB6 NSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYL
       .. : :.:..::.:::::::.::: :::.::.. .: :. :: .  . .... .::::::
CCDS30 KNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYL
            230       240       250       260       270       280  

        210       220       230       240       250       260      
pF1KB6 PKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPL
       : ::.:.::. : : . :::..::.::.:::.:.:::::.: .. ::: ..::   ..::
CCDS30 PLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPL
            290       300       310       320       330       340  

        270       280       290       300       310       320      
pF1KB6 RLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYC
        :::::::. ..::::::::..:::.:::::.:::.::: ::..::.....:. .::.  
CCDS30 YLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKF
            350       360       370       380       390       400  

        330       340  
pF1KB6 RQKIQEALHACPLG  
       :::..:::        
CCDS30 RQKLEEALRESQGKPG
            410        

>>CCDS1464.1 RASSF5 gene_id:83593|Hs108|chr1              (265 aa)
 initn: 754 init1: 754 opt: 754  Z-score: 811.4  bits: 158.2 E(32554): 7.1e-39
Smith-Waterman score: 754; 53.5% identity (81.6% similar) in 217 aa overlap (118-334:41-257)

        90       100       110       120       130       140       
pF1KB6 TCHYRCRALVCLDCCGPRDLGWEPAVERDTNVDEPVEWETPDLSQAEIEQKIKEYNAQIN
                                     :: .:::      .  ::.:::  ::.. .
CCDS14 YCSLDEELEDCFFTAKTTFFRNAQSKHLSKNVCKPVEETQRPPTLQEIKQKIDSYNTREK
               20        30        40        50        60        70

       150       160       170       180       190       200       
pF1KB6 SNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLP
       . : :.:..::.:::::::.::: :::.::.. .: :. :: .  . .... .:::::::
CCDS14 NCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFYLP
               80        90       100       110       120       130

       210       220       230       240       250       260       
pF1KB6 KDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLR
        ::.:.::. : : . :::..::.::.:::.:.:::::.: .. ::: ..::   ..:: 
CCDS14 LDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADRPLY
              140       150       160       170       180       190

       270       280       290       300       310       320       
pF1KB6 LRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCR
       :::::::. ..::::::::..:::.:::::.:::.::: ::..::.....:. .::.  :
CCDS14 LRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQKKYDKFR
              200       210       220       230       240       250

       330       340  
pF1KB6 QKIQEALHACPLG  
       ::..:::        
CCDS14 QKLEEALRESQGKPG
              260     

>>CCDS1463.1 RASSF5 gene_id:83593|Hs108|chr1              (336 aa)
 initn: 614 init1: 440 opt: 628  Z-score: 675.4  bits: 133.4 E(32554): 2.7e-31
Smith-Waterman score: 628; 44.8% identity (67.2% similar) in 259 aa overlap (11-254:81-330)

                                   10        20        30        40
pF1KB6                     MSGEPELIELRELAPAGRAGKGRTRLERANALRIARGTAC
                                     : : : :   . : :   :   : .:.   
CCDS14 STAPGAREGRSARRAARGNLEPPPRASRPARPLRP-GLQQRLRRR-PGAPRPRDVRSIFE
               60        70        80         90        100        

                  50            60        70        80        90   
pF1KB6 NPTRQLVP---GRGHRFQ----PAGPATHTWCDLCGDFIWGVVRKGLQCAHCKFTCHYRC
       .:    ::   :.:: :     :.::.   ::::::     :.:..:.:..:::::: .:
CCDS14 QPQDPRVPAERGEGHCFAELVLPGGPG---WCDLCGRE---VLRQALRCTNCKFTCHPEC
      110       120       130          140          150       160  

           100       110              120        130       140     
pF1KB6 RALVCLDCCGPRDLGWE-PAVER------DTNVDEPVEW-ETPDLSQAEIEQKIKEYNAQ
       :.:. :::   . :. . :. :       . :: .:::  . :   : ::.:::  ::..
CCDS14 RSLIQLDCSQQEGLSRDRPSPESTLTVTFSQNVCKPVEETQRPPTLQ-EIKQKIDSYNTR
            170       180       190       200        210       220 

         150       160       170       180       190       200     
pF1KB6 INSNLFMSLNKDGSYTGFIKVQLKLVRPVSVPSSKKPPSLQDARRGPGRGTSVRRRTSFY
        .. : :.:..::.:::::::.::: :::.::.. .: :. :: .  . .... .:::::
CCDS14 EKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKRTSFY
             230       240       250       260       270       280 

         210       220       230       240       250       260     
pF1KB6 LPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQP
       :: ::.:.::. : : . :::..::.::.:::.:.:::::.: .. :::           
CCDS14 LPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVGCLLHP     
             290       300       310       320       330           

         270       280       290       300       310       320     
pF1KB6 LRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSY

>>CCDS8969.1 RASSF3 gene_id:283349|Hs108|chr12            (238 aa)
 initn: 570 init1: 269 opt: 430  Z-score: 466.3  bits: 94.2 E(32554): 1.2e-19
Smith-Waterman score: 539; 45.0% identity (71.2% similar) in 222 aa overlap (115-334:33-231)

           90       100       110       120        130       140   
pF1KB6 CKFTCHYRCRALVCLDCCGPRDLGWEPAVERDTNVDEPVEWETPD-LSQAEIEQKIKEYN
                                     :. . :   : :: . ::. ::..:...::
CCDS89 SGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHKYN
             10        20        30        40        50        60  

           150       160       170        180       190       200  
pF1KB6 AQINSNLFMSLNKDGSYTGFIKVQLKLVRPVSV-PSSKKPPSLQDARRGPGRGTSVRRRT
         ....: :.::..: ::::::::..: .: .. :.: :   :. .  :           
CCDS89 LAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGK---LSPSSNG-----------
             70        80        90       100                      

            210       220       230       240       250       260  
pF1KB6 SFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDD
               .. ::. : . . :::::::.::::...: ::::..: .:. :::  :: : 
CCDS89 -------CMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDR
             110       120       130       140       150       160 

            270       280       290       300       310       320  
pF1KB6 EQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQK
       :.:: :::.:::   .:::::.:.. ::  :.:::.:::.::::::..::.:.:... ..
CCDS89 EHPLYLRLVAGPRTDTLSFVLREHEIGE--WEAFSLPELQNFLRILDKEEDEQLQNLKRR
             170       180         190       200       210         

            330       340 
pF1KB6 YSYCRQKIQEALHACPLG 
       :.  :::..:::       
CCDS89 YTAYRQKLEEALREVWKPD
     220       230        




340 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 16:43:40 2016 done: Fri Nov  4 16:43:41 2016
 Total Scan time:  2.450 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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