Result of FASTA (omim) for pF1KB5035
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5035, 192 aa
  1>>>pF1KB5035 192 - 192 aa - 192 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0230+/-0.000303; mu= 6.0672+/- 0.019
 mean_var=130.8119+/-26.105, 0's: 0 Z-trim(120.4): 28  B-trim: 0 in 0/54
 Lambda= 0.112137
 statistics sampled from 35620 (35649) to 35620 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.418), width:  16
 Scan time:  6.350

The best scores are:                                      opt bits E(85289)
NP_005953 (OMIM: 176807,600020) max-interacting pr ( 228) 1240 211.0 1.2e-54
NP_569157 (OMIM: 176807,600020) max-interacting pr ( 295) 1240 211.0 1.4e-54
NP_001008541 (OMIM: 176807,600020) max-interacting ( 182)  979 168.7   5e-42
NP_002348 (OMIM: 600021) max dimerization protein  ( 221)  672 119.1 5.2e-27
NP_001189442 (OMIM: 600021) max dimerization prote ( 220)  654 116.2 3.9e-26
NP_001189443 (OMIM: 600021) max dimerization prote ( 211)  602 107.7 1.3e-23
NP_112590 (OMIM: 609450) max dimerization protein  ( 206)  427 79.4 4.2e-15
NP_001136407 (OMIM: 609450) max dimerization prote ( 193)  370 70.2 2.4e-12
NP_064706 (OMIM: 603039) max-binding protein MNT [ ( 582)  217 45.8 0.00016
XP_011522170 (OMIM: 603039) PREDICTED: max-binding ( 590)  217 45.8 0.00016


>>NP_005953 (OMIM: 176807,600020) max-interacting protei  (228 aa)
 initn: 1240 init1: 1240 opt: 1240  Z-score: 1102.3  bits: 211.0 E(85289): 1.2e-54
Smith-Waterman score: 1240; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:37-228)

                                             10        20        30
pF1KB5                               MPSPRLQHSKPPRRLSRAQKHSSGSSNTST
                                     ::::::::::::::::::::::::::::::
NP_005 INVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTST
         10        20        30        40        50        60      

               40        50        60        70        80        90
pF1KB5 ANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKS
         70        80        90       100       110       120      

              100       110       120       130       140       150
pF1KB5 QHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEF
        130       140       150       160       170       180      

              160       170       180       190  
pF1KB5 SHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
       ::::::::::::::::::::::::::::::::::::::::::
NP_005 SHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
        190       200       210       220        

>>NP_569157 (OMIM: 176807,600020) max-interacting protei  (295 aa)
 initn: 1240 init1: 1240 opt: 1240  Z-score: 1100.7  bits: 211.0 E(85289): 1.4e-54
Smith-Waterman score: 1240; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:104-295)

                                             10        20        30
pF1KB5                               MPSPRLQHSKPPRRLSRAQKHSSGSSNTST
                                     ::::::::::::::::::::::::::::::
NP_569 QILLEAASYLEQIEKENKKCEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTST
            80        90       100       110       120       130   

               40        50        60        70        80        90
pF1KB5 ANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 ANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKS
           140       150       160       170       180       190   

              100       110       120       130       140       150
pF1KB5 QHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 QHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEF
           200       210       220       230       240       250   

              160       170       180       190  
pF1KB5 SHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
       ::::::::::::::::::::::::::::::::::::::::::
NP_569 SHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
           260       270       280       290     

>>NP_001008541 (OMIM: 176807,600020) max-interacting pro  (182 aa)
 initn: 970 init1: 970 opt: 979  Z-score: 875.5  bits: 168.7 E(85289): 5e-42
Smith-Waterman score: 1146; 94.8% identity (94.8% similar) in 192 aa overlap (1-192:1-182)

               10        20        30        40        50        60
pF1KB5 MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPL
       :::::::::::::::::::::::::::::::::          :::::::::::::::::
NP_001 MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANR----------RAHLRLCLERLKVLIPL
               10        20        30                  40        50

               70        80        90       100       110       120
pF1KB5 GPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERI
               60        70        80        90       100       110

              130       140       150       160       170       180
pF1KB5 RMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEG
              120       130       140       150       160       170

              190  
pF1KB5 YSSASVKLSFTS
       ::::::::::::
NP_001 YSSASVKLSFTS
              180  

>>NP_002348 (OMIM: 600021) max dimerization protein 1 is  (221 aa)
 initn: 646 init1: 377 opt: 672  Z-score: 605.9  bits: 119.1 E(85289): 5.2e-27
Smith-Waterman score: 672; 61.8% identity (87.6% similar) in 170 aa overlap (18-187:43-207)

                            10        20        30        40       
pF1KB5              MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHL
                                     : :. . :.......::::::.::::::::
NP_002 LEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNNSSSRSTHNEMEKNRRAHL
             20        30        40        50        60        70  

        50        60        70        80        90       100       
pF1KB5 RLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWR
       :::::.:: :.::::. .:::::.::.::: ::::::. .::. ::...:.:::: :: .
NP_002 RLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQIDQLQREQRHLKRQ
             80        90       100       110       120       130  

       110       120       130       140       150       160       
pF1KB5 LEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDID
       ::.:     .:::::::::::.::.::::.::::.::::::..  :..:  :..:.:: :
NP_002 LEKLG----IERIRMDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLD-WSSSSVSDSD
                140       150       160       170        180       

       170       180       190           
pF1KB5 DHSSLPSIGSDEGYSSASVKLSFTS         
       ...:. :.::::::::.:.:              
NP_002 ERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
       190       200       210       220 

>>NP_001189442 (OMIM: 600021) max dimerization protein 1  (220 aa)
 initn: 634 init1: 377 opt: 654  Z-score: 590.2  bits: 116.2 E(85289): 3.9e-26
Smith-Waterman score: 654; 61.2% identity (87.1% similar) in 170 aa overlap (18-187:43-206)

                            10        20        30        40       
pF1KB5              MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHL
                                     : :. . :.......::::::.::::::::
NP_001 LEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNNSSSRSTHNEMEKNRRAHL
             20        30        40        50        60        70  

        50        60        70        80        90       100       
pF1KB5 RLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWR
       :::::.:: :.::::. .:::::.::.::: ::::::. .::. ::...:.:::: :: .
NP_001 RLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQIDQLQREQRHLKRQ
             80        90       100       110       120       130  

       110       120       130       140       150       160       
pF1KB5 LEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDID
       ::.:     .:::::::::::.::.::::.:: :.::::::..  :..:  :..:.:: :
NP_001 LEKLG----IERIRMDSIGSTVSSERSDSDRE-IDVDVESTDYLTGDLD-WSSSSVSDSD
                140       150       160        170        180      

       170       180       190           
pF1KB5 DHSSLPSIGSDEGYSSASVKLSFTS         
       ...:. :.::::::::.:.:              
NP_001 ERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
        190       200       210       220

>>NP_001189443 (OMIM: 600021) max dimerization protein 1  (211 aa)
 initn: 606 init1: 315 opt: 602  Z-score: 545.0  bits: 107.7 E(85289): 1.3e-23
Smith-Waterman score: 602; 62.2% identity (87.2% similar) in 156 aa overlap (32-187:48-197)

              10        20        30        40        50        60 
pF1KB5 PSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLG
                                     :.: .:.  ..::::::::::.:: :.:::
NP_001 YLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNN-SSSRRAHLRLCLEKLKGLVPLG
        20        30        40        50         60        70      

              70        80        90       100       110       120 
pF1KB5 PDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIR
       :. .:::::.::.::: ::::::. .::. ::...:.:::: :: .::.: :   .::::
NP_001 PESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQIDQLQREQRHLKRQLEKL-G---IERIR
         80        90       100       110       120           130  

             130       140       150       160       170       180 
pF1KB5 MDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGY
       :::::::.::.::::.::::.::::::..  :..:  :..:.:: :...:. :.::::::
NP_001 MDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLD-WSSSSVSDSDERGSMQSLGSDEGY
            140       150       160        170       180       190 

             190           
pF1KB5 SSASVKLSFTS         
       ::.:.:              
NP_001 SSTSIKRIKLQDSHKACLGL
             200       210 

>>NP_112590 (OMIM: 609450) max dimerization protein 3 is  (206 aa)
 initn: 381 init1: 297 opt: 427  Z-score: 392.1  bits: 79.4 E(85289): 4.2e-15
Smith-Waterman score: 427; 47.7% identity (76.2% similar) in 151 aa overlap (10-156:36-185)

                                    10        20        30         
pF1KB5                      MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNEL
                                     . :  . : .:.   . ... ..::.::::
NP_112 SNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNEL
          10        20        30        40        50        60     

      40        50        60        70        80        90         
pF1KB5 EKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLER
       :: :::.:. ::::::  .::: ::.:.:::.:: .:. ::.:::. :.....  : :. 
NP_112 EKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRS
          70        80        90       100       110       120     

     100       110          120        130       140       150     
pF1KB5 EQRFLKWRLEQLQG---PQEMERIRMDSIGST-ISSDRSDSEREEIEVDVESTEFSHGEV
       .:. :. .::::.:     : ::.: ::. :. .::.::::..::.::::::  :. ::.
NP_112 KQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFG-GEA
         130       140       150       160       170       180     

         160       170       180       190  
pF1KB5 DNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
       .                                    
NP_112 ELLRGFVAGQEHSYSHGGGAWL               
          190       200                     

>>NP_001136407 (OMIM: 609450) max dimerization protein 3  (193 aa)
 initn: 356 init1: 297 opt: 370  Z-score: 342.7  bits: 70.2 E(85289): 2.4e-12
Smith-Waterman score: 370; 45.9% identity (75.2% similar) in 133 aa overlap (10-138:36-168)

                                    10        20        30         
pF1KB5                      MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNEL
                                     . :  . : .:.   . ... ..::.::::
NP_001 SNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNEL
          10        20        30        40        50        60     

      40        50        60        70        80        90         
pF1KB5 EKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLER
       :: :::.:. ::::::  .::: ::.:.:::.:: .:. ::.:::. :.....  : :. 
NP_001 EKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRS
          70        80        90       100       110       120     

     100       110          120        130       140       150     
pF1KB5 EQRFLKWRLEQLQG---PQEMERIRMDSIGST-ISSDRSDSEREEIEVDVESTEFSHGEV
       .:. :. .::::.:     : ::.: ::. :. .::.::::..                 
NP_001 KQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQVLPNENGGTPNHRPTGR
         130       140       150       160       170       180     

         160       170       180       190  
pF1KB5 DNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
                                            
NP_001 GNNISSHH                             
         190                                

>>NP_064706 (OMIM: 603039) max-binding protein MNT [Homo  (582 aa)
 initn: 120 init1: 120 opt: 217  Z-score: 202.1  bits: 45.8 E(85289): 0.00016
Smith-Waterman score: 217; 36.0% identity (59.6% similar) in 161 aa overlap (2-158:192-339)

                                            10           20        
pF1KB5                              MPSPRLQHSK--PPRRL-SRAQKHSSGSSNT
                                     : : :   :  : ... :  ::.  :. .:
NP_064 SPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGT
             170       180       190       200       210       220 

       30        40        50        60        70        80        
pF1KB5 STANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAER
           : .::.:::::::::. :.: ::  :: . :  . ..:..:  :  .:..:.. :.
NP_064 ----REVHNKLEKNRRAHLKECFETLKRNIP-NVDDKKTSNLSVLRTALRYIQSLKRKEK
                 230       240        250       260       270      

       90       100       110       120       130       140        
pF1KB5 KSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVEST
       . .:..: : ::.   . :: .:.  .:. .  ::    ..  ::   .  . : :  ::
NP_064 EYEHEMERLAREKIATQQRLAELK--HELSQW-MD----VLEIDRVLRQTGQPEDDQAST
        280       290       300              310       320         

      150        160       170       180       190                 
pF1KB5 EF-SHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS               
          :.:: :::                                                 
NP_064 STASEGE-DNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHS
     330        340       350       360       370       380        

>>XP_011522170 (OMIM: 603039) PREDICTED: max-binding pro  (590 aa)
 initn: 146 init1: 120 opt: 217  Z-score: 202.0  bits: 45.8 E(85289): 0.00016
Smith-Waterman score: 217; 36.0% identity (59.6% similar) in 161 aa overlap (2-158:200-347)

                                            10           20        
pF1KB5                              MPSPRLQHSK--PPRRL-SRAQKHSSGSSNT
                                     : : :   :  : ... :  ::.  :. .:
XP_011 SPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGT
     170       180       190       200       210       220         

       30        40        50        60        70        80        
pF1KB5 STANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAER
           : .::.:::::::::. :.: ::  :: . :  . ..:..:  :  .:..:.. :.
XP_011 ----REVHNKLEKNRRAHLKECFETLKRNIP-NVDDKKTSNLSVLRTALRYIQSLKRKEK
         230       240       250        260       270       280    

       90       100       110       120       130       140        
pF1KB5 KSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVEST
       . .:..: : ::.   . :: .:.  .:. .  ::    ..  ::   .  . : :  ::
XP_011 EYEHEMERLAREKIATQQRLAELK--HELSQW-MD----VLEIDRVLRQTGQPEDDQAST
          290       300         310            320       330       

      150        160       170       180       190                 
pF1KB5 EF-SHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS               
          :.:: :::                                                 
XP_011 STASEGE-DNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHS
       340        350       360       370       380       390      




192 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:27:03 2016 done: Fri Nov  4 20:27:04 2016
 Total Scan time:  6.350 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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