Result of FASTA (omim) for pF1KB9771
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9771, 538 aa
  1>>>pF1KB9771 538 - 538 aa - 538 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.4102+/-0.000429; mu= 4.8252+/- 0.027
 mean_var=222.1072+/-46.831, 0's: 0 Z-trim(118.3): 117  B-trim: 1504 in 1/54
 Lambda= 0.086058
 statistics sampled from 31028 (31193) to 31028 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.366), width:  16
 Scan time: 11.330

The best scores are:                                      opt bits E(85289)
NP_005048 (OMIM: 600697) retinoblastoma-binding pr ( 538) 3620 462.7 1.3e-129
XP_011508135 (OMIM: 600697) PREDICTED: retinoblast ( 537) 3603 460.6 5.5e-129
NP_001180201 (OMIM: 600697) retinoblastoma-binding ( 500) 3315 424.8  3e-118
NP_001180202 (OMIM: 600697) retinoblastoma-binding ( 410) 2699 348.3 2.8e-95


>>NP_005048 (OMIM: 600697) retinoblastoma-binding protei  (538 aa)
 initn: 3620 init1: 3620 opt: 3620  Z-score: 2448.1  bits: 462.7 E(85289): 1.3e-129
Smith-Waterman score: 3620; 99.8% identity (99.8% similar) in 538 aa overlap (1-538:1-538)

               10        20        30        40        50        60
pF1KB9 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 NKVLVCPMKSAPVMLTLSDSKHVFLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
       ::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_005 NKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
              430       440       450       460       470       480

              490       500       510       520       530        
pF1KB9 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL
              490       500       510       520       530        

>>XP_011508135 (OMIM: 600697) PREDICTED: retinoblastoma-  (537 aa)
 initn: 3600 init1: 3576 opt: 3603  Z-score: 2436.7  bits: 460.6 E(85289): 5.5e-129
Smith-Waterman score: 3603; 99.6% identity (99.6% similar) in 538 aa overlap (1-538:1-537)

               10        20        30        40        50        60
pF1KB9 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 NKVLVCPMKSAPVMLTLSDSKHVFLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
       ::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
XP_011 NKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
              430       440       450       460       470       480

              490       500       510       520       530        
pF1KB9 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL
       ::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_011 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLT-GGAISELL
              490       500       510       520        530       

>>NP_001180201 (OMIM: 600697) retinoblastoma-binding pro  (500 aa)
 initn: 3315 init1: 3315 opt: 3315  Z-score: 2243.9  bits: 424.8 E(85289): 3e-118
Smith-Waterman score: 3315; 99.8% identity (99.8% similar) in 491 aa overlap (1-491:1-491)

               10        20        30        40        50        60
pF1KB9 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 NKVLVCPMKSAPVMLTLSDSKHVFLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
       ::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_001 NKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
              430       440       450       460       470       480

              490       500       510       520       530        
pF1KB9 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL
       :::::::::::                                               
NP_001 KKQAGRPKGSKAGGAISELL                                      
              490       500                                      

>>NP_001180202 (OMIM: 600697) retinoblastoma-binding pro  (410 aa)
 initn: 2696 init1: 2672 opt: 2699  Z-score: 1831.7  bits: 348.3 E(85289): 2.8e-95
Smith-Waterman score: 2699; 99.5% identity (99.5% similar) in 411 aa overlap (128-538:1-410)

       100       110       120       130       140       150       
pF1KB9 GDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVFLPVDDDSDLNVVA
                                     :::::::::::::::: :::::::::::::
NP_001                               MKSAPVMLTLSDSKHVVLPVDDDSDLNVVA
                                             10        20        30

       160       170       180       190       200       210       
pF1KB9 SFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINT
               40        50        60        70        80        90

       220       230       240       250       260       270       
pF1KB9 ADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALY
              100       110       120       130       140       150

       280       290       300       310       320       330       
pF1KB9 IWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFK
              160       170       180       190       200       210

       340       350       360       370       380       390       
pF1KB9 ELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSK
              220       230       240       250       260       270

       400       410       420       430       440       450       
pF1KB9 ALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNI
              280       290       300       310       320       330

       460       470       480       490       500       510       
pF1KB9 ELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAK
              340       350       360       370       380       390

       520       530        
pF1KB9 GKVQAELSQPLTAGGAISELL
       :::::::::::: ::::::::
NP_001 GKVQAELSQPLT-GGAISELL
              400        410




538 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 21:27:07 2016 done: Fri Nov  4 21:27:09 2016
 Total Scan time: 11.330 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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