Result of FASTA (omim) for
pF1KB5694
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5694, 646 aa
1>>>pF1KB5694 646 - 646 aa - 646 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8596+/-0.000453; mu= 12.6860+/- 0.028
mean_var=207.3728+/-42.166, 0's: 0 Z-trim(115.9): 287 B-trim: 0 in 0/59
Lambda= 0.089063
statistics sampled from 26365 (26721) to 26365 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.313), width: 16
Scan time: 12.330
The best scores are: opt bits E(85289)
NP_006491 (OMIM: 155735) cell surface glycoprotein ( 646) 4297 566.0 1.5e-160
XP_016873250 (OMIM: 155735) PREDICTED: cell surfac ( 604) 3977 524.8 3.4e-148
XP_016873249 (OMIM: 155735) PREDICTED: cell surfac ( 614) 3470 459.7 1.4e-128
XP_016873251 (OMIM: 155735) PREDICTED: cell surfac ( 583) 3344 443.5 1e-123
XP_016873248 (OMIM: 155735) PREDICTED: cell surfac ( 625) 3344 443.5 1.1e-123
NP_001013275 (OMIM: 111200,247420,612773) basal ce ( 588) 635 95.4 6.3e-19
NP_005572 (OMIM: 111200,247420,612773) basal cell ( 628) 635 95.4 6.5e-19
NP_001230210 (OMIM: 601662) CD166 antigen isoform ( 555) 450 71.6 8.7e-12
NP_001230209 (OMIM: 601662) CD166 antigen isoform ( 570) 450 71.6 8.8e-12
NP_001618 (OMIM: 601662) CD166 antigen isoform 1 p ( 583) 450 71.6 8.9e-12
NP_001193883 (OMIM: 600214) advanced glycosylation ( 325) 288 50.5 1.2e-05
NP_001193865 (OMIM: 600214) advanced glycosylation ( 355) 288 50.5 1.2e-05
NP_001193869 (OMIM: 600214) advanced glycosylation ( 347) 286 50.2 1.4e-05
NP_001193895 (OMIM: 600214) advanced glycosylation ( 347) 286 50.2 1.4e-05
NP_001139317 (OMIM: 602430) roundabout homolog 1 i (1551) 293 52.0 1.9e-05
XP_011532282 (OMIM: 602430) PREDICTED: roundabout (1590) 293 52.0 1.9e-05
XP_011532281 (OMIM: 602430) PREDICTED: roundabout (1599) 293 52.0 2e-05
NP_598334 (OMIM: 602430) roundabout homolog 1 isof (1606) 293 52.0 2e-05
XP_006713340 (OMIM: 602430) PREDICTED: roundabout (1615) 293 52.0 2e-05
XP_016862471 (OMIM: 602430) PREDICTED: roundabout (1626) 293 52.0 2e-05
XP_011532280 (OMIM: 602430) PREDICTED: roundabout (1645) 293 52.0 2e-05
XP_011532278 (OMIM: 602430) PREDICTED: roundabout (1654) 293 52.0 2e-05
XP_011532279 (OMIM: 602430) PREDICTED: roundabout (1654) 293 52.0 2e-05
NP_001127 (OMIM: 600214) advanced glycosylation en ( 404) 282 49.8 2.2e-05
NP_001193861 (OMIM: 600214) advanced glycosylation ( 390) 267 47.9 8.4e-05
NP_751947 (OMIM: 600214) advanced glycosylation en ( 342) 260 46.9 0.00014
XP_016857926 (OMIM: 603075,608548) PREDICTED: hemi (4976) 268 49.4 0.00036
XP_011508340 (OMIM: 603075,608548) PREDICTED: hemi (5518) 268 49.5 0.00039
NP_114141 (OMIM: 603075,608548) hemicentin-1 precu (5635) 268 49.5 0.00039
NP_005520 (OMIM: 142461,224410,255800) basement me (4391) 253 47.4 0.0013
NP_001278789 (OMIM: 142461,224410,255800) basement (4392) 253 47.4 0.0013
XP_016856611 (OMIM: 142461,224410,255800) PREDICTE (4438) 253 47.4 0.0013
XP_016856610 (OMIM: 142461,224410,255800) PREDICTE (4439) 253 47.4 0.0013
XP_016856609 (OMIM: 142461,224410,255800) PREDICTE (4456) 253 47.4 0.0013
XP_011539620 (OMIM: 142461,224410,255800) PREDICTE (4574) 253 47.5 0.0013
NP_001171744 (OMIM: 109770) carcinoembryonic antig ( 461) 230 43.2 0.0025
XP_011519761 (OMIM: 613261) PREDICTED: protogenin ( 701) 231 43.6 0.003
NP_878250 (OMIM: 611128) MAM domain-containing gly ( 727) 231 43.6 0.003
XP_016877571 (OMIM: 613261) PREDICTED: protogenin ( 927) 231 43.7 0.0035
XP_016877570 (OMIM: 613261) PREDICTED: protogenin (1072) 231 43.8 0.0038
NP_776175 (OMIM: 613261) protogenin precursor [Hom (1150) 231 43.8 0.004
XP_016862474 (OMIM: 602430) PREDICTED: roundabout (1535) 228 43.6 0.0062
XP_011527436 (OMIM: 603889) PREDICTED: signal-regu ( 381) 218 41.6 0.0065
>>NP_006491 (OMIM: 155735) cell surface glycoprotein MUC (646 aa)
initn: 4297 init1: 4297 opt: 4297 Z-score: 3003.4 bits: 566.0 E(85289): 1.5e-160
Smith-Waterman score: 4297; 99.8% identity (99.8% similar) in 646 aa overlap (1-646:1-646)
10 20 30 40 50 60
pF1KB5 MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DWFSVHKEKRTLIFRVRQGQGQSEPGEYGQRLSLQDRGATLALTQVTPQDERIFLCQGKR
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
NP_006 DWFSVHKEKRTLIFRVRQGQGQSEPGEYEQRLSLQDRGATLALTQVTPQDERIFLCQGKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 QLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 TRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITL
550 560 570 580 590 600
610 620 630 640
pF1KB5 PPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
610 620 630 640
>>XP_016873250 (OMIM: 155735) PREDICTED: cell surface gl (604 aa)
initn: 4010 init1: 3977 opt: 3977 Z-score: 2781.5 bits: 524.8 E(85289): 3.4e-148
Smith-Waterman score: 3977; 99.7% identity (99.8% similar) in 598 aa overlap (1-598:1-598)
10 20 30 40 50 60
pF1KB5 MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DWFSVHKEKRTLIFRVRQGQGQSEPGEYGQRLSLQDRGATLALTQVTPQDERIFLCQGKR
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_016 DWFSVHKEKRTLIFRVRQGQGQSEPGEYEQRLSLQDRGATLALTQVTPQDERIFLCQGKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 QLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 TRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 TRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEMER
550 560 570 580 590 600
610 620 630 640
pF1KB5 PPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
XP_016 NTSI
>>XP_016873249 (OMIM: 155735) PREDICTED: cell surface gl (614 aa)
initn: 4094 init1: 3470 opt: 3470 Z-score: 2429.3 bits: 459.7 E(85289): 1.4e-128
Smith-Waterman score: 4034; 94.9% identity (94.9% similar) in 646 aa overlap (1-646:1-614)
10 20 30 40 50 60
pF1KB5 MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DWFSVHKEKRTLIFRVRQGQGQSEPGEYGQRLSLQDRGATLALTQVTPQDERIFLCQGKR
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_016 DWFSVHKEKRTLIFRVRQGQGQSEPGEYEQRLSLQDRGATLALTQVTPQDERIFLCQGKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 QLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPH
::::::::::::::::::::::::::::::::::::
XP_016 LSTLNVLVTPELLETGVECTASNDLGKNTSILFLEL------------------------
490 500 510
550 560 570 580 590 600
pF1KB5 TRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------ERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITL
520 530 540 550 560
610 620 630 640
pF1KB5 PPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
570 580 590 600 610
>>XP_016873251 (OMIM: 155735) PREDICTED: cell surface gl (583 aa)
initn: 3841 init1: 3338 opt: 3344 Z-score: 2342.1 bits: 443.5 E(85289): 1e-123
Smith-Waterman score: 3793; 96.2% identity (96.3% similar) in 598 aa overlap (1-598:1-577)
10 20 30 40 50 60
pF1KB5 MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DWFSVHKEKRTLIFRVRQGQGQSEPGEYGQRLSLQDRGATLALTQVTPQDERIFLCQGKR
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_016 DWFSVHKEKRTLIFRVRQGQGQSEPGEYEQRLSLQDRGATLALTQVTPQDERIFLCQGKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 QLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPH
::::::::::::::: ::::::::::::::::::::::::
XP_016 LSTLNVLVTPELLET---------------------VNLTTLTPDSNTTTGLSTSTASPH
490 500 510
550 560 570 580 590 600
pF1KB5 TRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 TRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEMER
520 530 540 550 560 570
610 620 630 640
pF1KB5 PPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
XP_016 NTSI
580
>>XP_016873248 (OMIM: 155735) PREDICTED: cell surface gl (625 aa)
initn: 3338 init1: 3338 opt: 3344 Z-score: 2341.7 bits: 443.5 E(85289): 1.1e-123
Smith-Waterman score: 4113; 96.6% identity (96.6% similar) in 646 aa overlap (1-646:1-625)
10 20 30 40 50 60
pF1KB5 MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGLPRLVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DWFSVHKEKRTLIFRVRQGQGQSEPGEYGQRLSLQDRGATLALTQVTPQDERIFLCQGKR
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_016 DWFSVHKEKRTLIFRVRQGQGQSEPGEYEQRLSLQDRGATLALTQVTPQDERIFLCQGKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKEEKNRVHIQSSQTVESSGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTVPVFYPTEKVWLEVEPVGMLKEGDRVEIRCLADGNPPPHFSISKQNPSTREAEEETTN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAPERQEGSS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSIPGLNRT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 QLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTASEQDQDPQRV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPH
::::::::::::::: ::::::::::::::::::::::::
XP_016 LSTLNVLVTPELLET---------------------VNLTTLTPDSNTTTGLSTSTASPH
490 500 510
550 560 570 580 590 600
pF1KB5 TRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITL
520 530 540 550 560 570
610 620 630 640
pF1KB5 PPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
580 590 600 610 620
>>NP_001013275 (OMIM: 111200,247420,612773) basal cell a (588 aa)
initn: 540 init1: 163 opt: 635 Z-score: 460.8 bits: 95.4 E(85289): 6.3e-19
Smith-Waterman score: 766; 30.0% identity (55.1% similar) in 624 aa overlap (2-597:12-585)
10 20 30 40
pF1KB5 MGLPRLVC-AFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCG
: :::. : :::: : . .:.. .: :::: :....: :
NP_001 MEPPDAPAQARGAPRLLLLAVLLAAH---P---DAQAEVRLSVPPLVEVMRGKSVILDCT
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 LSQSQGNLSHVDWFSVHKEKRTLIFRVRQGQGQ----SEPGEYGQRLSLQ-DRGATLALT
. .. . ..:: . . . . ::. . :. : : . :.:.
NP_001 PTGTHDHY-MLEWFLTDRSGARPRLASAEMQGSELQVTMHDTRGRSPPYQLDSQGRLVLA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 QVTPQDERIFLC--QGKRPRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCV
.. ::: ..: .. . : .: :. :: ... : . : .:.:::
NP_001 EAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCN
120 130 140 150 160 170
170 180 190 200 210
pF1KB5 GRNGYPIPQVIWYKNGRPLKE--EKNRVHIQSSQTV-ESSGLYTLQSILKAQLVKEDKDA
.::: : :.. ::.::. :. : : ..:.:: :.::: .: : : .: :.:.::
NP_001 SRNGNPAPKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKDDRDA
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 QFYCELNYRLPSGNHMK-ESREVTVPVFYPTEKV--WL--EVEPVGMLKEGDRVEIRCLA
.:.: .: :: : : . .: . . ::::.: :. :.: ..::: :.. : .
NP_001 SFHCAAHYSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQLLCRG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 DGNPPPHFSISKQNPSTREAEEETTNDN--GVLVLEPARKEHSGRYECQGLDLDTMISL-
::.: :.... . .. .::. : : : :.:: . . .:: : :. : :. ..
NP_001 DGSPSPEYTLFR----LQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQ
300 310 320 330 340
340 350 360 370 380 390
pF1KB5 LSEPQELLVNYVSDVRVSPAAPERQE-GSSLTLTCEAESSQDLEFQWLREETGQVLERGP
::. :: : :.. ...: . .:: ...: ... ..: .. : : ::
NP_001 LSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTP--LGDGP
350 360 370 380 390 400
400 410 420 430 440
pF1KB5 VLQLHDLKREAGGGYRCVASVPSIPGLNRTQLVNVAIFGPPWM--AFKERKV---WVKEN
.:.: .. ...: : : ::.:..: :.::: .. . : : . : : :. : .:.
NP_001 MLSLSSITFDSNGTYVCEASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGSW-REG
410 420 430 440 450 460
450 460 470 480 490 500
pF1KB5 MVLNLSCEASGHPRPTISWNVNGTASEQDQDPQR---VLSTLNVLVTPELLETGVECTAS
..: : : ::: : .::. : .: . : : : :.:.. :: : . :. : ::
NP_001 DEVTLICSARGHPDPKLSWSQLG-GSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEAS
470 480 490 500 510 520
510 520 530 540 550 560
pF1KB5 NDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPHTRANSTSTERKLPEPESRGVVI
: :.. .. . .:.::.: ::..
NP_001 NPHGNKRHVFHF--------------------GTVSPQTSQA--------------GVAV
530 540 550
570 580 590 600 610 620
pF1KB5 VAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITLPPSRKSELVVEVKSDKLPEEMG
.:: : . .: .. ::.: . .:: :: :. ...
NP_001 MAVAVSVGLLLLVVAVFYCVRRKGG-PCCRQRREKGAP
560 570 580
630 640
pF1KB5 LLQGSSGDKRAPGDQGEKYIDLRH
>>NP_005572 (OMIM: 111200,247420,612773) basal cell adhe (628 aa)
initn: 548 init1: 163 opt: 635 Z-score: 460.5 bits: 95.4 E(85289): 6.5e-19
Smith-Waterman score: 809; 29.7% identity (55.6% similar) in 669 aa overlap (2-640:12-627)
10 20 30 40
pF1KB5 MGLPRLVC-AFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCG
: :::. : :::: : . .:.. .: :::: :....: :
NP_005 MEPPDAPAQARGAPRLLLLAVLLAAH---P---DAQAEVRLSVPPLVEVMRGKSVILDCT
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 LSQSQGNLSHVDWFSVHKEKRTLIFRVRQGQGQ----SEPGEYGQRLSLQ-DRGATLALT
. .. . ..:: . . . . ::. . :. : : . :.:.
NP_005 PTGTHDHY-MLEWFLTDRSGARPRLASAEMQGSELQVTMHDTRGRSPPYQLDSQGRLVLA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 QVTPQDERIFLC--QGKRPRSQEYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCV
.. ::: ..: .. . : .: :. :: ... : . : .:.:::
NP_005 EAQVGDERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCN
120 130 140 150 160 170
170 180 190 200 210
pF1KB5 GRNGYPIPQVIWYKNGRPLKE--EKNRVHIQSSQTV-ESSGLYTLQSILKAQLVKEDKDA
.::: : :.. ::.::. :. : : ..:.:: :.::: .: : : .: :.:.::
NP_005 SRNGNPAPKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKDDRDA
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 QFYCELNYRLPSGNHMK-ESREVTVPVFYPTEKV--WL--EVEPVGMLKEGDRVEIRCLA
.:.: .: :: : : . .: . . ::::.: :. :.: ..::: :.. : .
NP_005 SFHCAAHYSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQLLCRG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 DGNPPPHFSISKQNPSTREAEEETTNDN--GVLVLEPARKEHSGRYECQGLDLDTMISL-
::.: :.... . .. .::. : : : :.:: . . .:: : :. : :. ..
NP_005 DGSPSPEYTLFR----LQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQ
300 310 320 330 340
340 350 360 370 380 390
pF1KB5 LSEPQELLVNYVSDVRVSPAAPERQE-GSSLTLTCEAESSQDLEFQWLREETGQVLERGP
::. :: : :.. ...: . .:: ...: ... ..: .. : : ::
NP_005 LSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPALRWTKDSTP--LGDGP
350 360 370 380 390 400
400 410 420 430 440
pF1KB5 VLQLHDLKREAGGGYRCVASVPSIPGLNRTQLVNVAIFGPPWM--AFKERKV---WVKEN
.:.: .. ...: : : ::.:..: :.::: .. . : : . : : :. : .:.
NP_005 MLSLSSITFDSNGTYVCEASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGSW-REG
410 420 430 440 450 460
450 460 470 480 490 500
pF1KB5 MVLNLSCEASGHPRPTISWNVNGTASEQDQDPQR---VLSTLNVLVTPELLETGVECTAS
..: : : ::: : .::. : .: . : : : :.:.. :: : . :. : ::
NP_005 DEVTLICSARGHPDPKLSWSQLG-GSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEAS
470 480 490 500 510 520
510 520 530 540 550 560
pF1KB5 NDLGKNTSILFLELVNLTTLTPDSNTTTGLSTSTASPHTRANSTSTERKLPEPESRGVVI
: :.. .. . .:.::.: ::..
NP_005 NPHGNKRHVFHF--------------------GTVSPQTSQA--------------GVAV
530 540 550
570 580 590 600 610 620
pF1KB5 VAVIVCILVLAVLGAVLYFLYKKGKLPCRRSGKQEITLPPSRKSELVVEVKSDKLPEEMG
.:: : . .: .. ::.: . .:: :: :. ... . ::.. . . .... ::. :
NP_005 MAVAVSVGLLLLVVAVFYCVRRKGG-PCCRQRREKGAPPPGEPG---LSHSGSEQPEQTG
560 570 580 590 600
630 640
pF1KB5 LLQG--SSGDKRAPGDQGEKYIDLRH
::.: :.: . . : :..
NP_005 LLMGGASGGARGGSGGFGDEC
610 620
>>NP_001230210 (OMIM: 601662) CD166 antigen isoform 3 pr (555 aa)
initn: 222 init1: 140 opt: 450 Z-score: 332.6 bits: 71.6 E(85289): 8.7e-12
Smith-Waterman score: 631; 24.9% identity (59.8% similar) in 570 aa overlap (36-587:31-555)
10 20 30 40 50 60
pF1KB5 LVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHVDWFSV
:. :.: .. : :. : :: :
NP_001 MESKGASSCRLLFCLLISATVFRPGLGWYTVNSAYGDTIIIPCRLDVPQ-NLMFGKWKYE
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 HKEKRTLIFRVRQGQGQS----EPGEYGQRLSLQDRGATLALTQVTPQDERIFLCQGKRP
. . ... :.. .: . :: .::.:.. . ::..... .::. :.:.
NP_001 KPDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSE-NYTLSISNARISDEKRFVCMLVTE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 RSQ-EYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
. : ..:.: : .:.: . : . .... .... :.....:: .. ::.::.
NP_001 DNVFEAPTIVKVFKQPSKPEIVSKALFL--ETEQLKKLGDCISEDSYPDGNITWYRNGKV
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 LKEEKNRVHIQSSQTVES-SGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESR
:. .. : : .. .. . :::. : :. . .: : . : : ..: :::.. .:.
NP_001 LHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 EVTVPVFYPTEKVWLEV-EPVGMLKEGDRVEIRCLADGNPPPH---FSISKQNPSTREAE
... ..::::.: ..: : . .:::: . ..::..:::::. : . : . : ..
NP_001 QAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 EETTNDNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAP-E
: .: .:.. .: :.:. .: .::. . :.:. :. ..:..
NP_001 TYTLTD--------VRRNATGDYKCSLIDKKSMIA----STAITVHYL-DLSLNPSGEVT
300 310 320 330 340
360 370 380 390 400 410
pF1KB5 RQEGSSLTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSI
:: :..: ..: .:.. :.... :. .: .. .:. . .:.: : ... .
NP_001 RQIGDALPVSCTISASRNATVVWMKDNI--RLRSSP--SFSSLHYQDAGNYVCETALQEV
350 360 370 380 390
420 430 440 450 460 470
pF1KB5 PGLNRTQLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTAS---
::.. . ... . : : . : : .. .. :.. : :.:.:.:...:..:
NP_001 EGLKKRESLTLIVEGKPQI--KMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVIN
400 410 420 430 440 450
480 490 500 510 520
pF1KB5 EQDQDPQ---RVLSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNT
. ...: : : .....:: .. . ::: :.: .... : . ... :.
NP_001 QTEESPYINGRYYS--KIIISPEE-NVTLTCTAENQLERTVNSLNVSAISI----PE---
460 470 480 490 500
530 540 550 560 570 580
pF1KB5 TTGLSTSTASPHTRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLY-KKGK
: .:. : : . . .... .::...: .:. :....:.:.:: ::.:
NP_001 -----------HDEADEISDENR-EKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSK
510 520 530 540 550
590 600 610 620 630 640
pF1KB5 LPCRRSGKQEITLPPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
>>NP_001230209 (OMIM: 601662) CD166 antigen isoform 2 pr (570 aa)
initn: 212 init1: 140 opt: 450 Z-score: 332.5 bits: 71.6 E(85289): 8.8e-12
Smith-Waterman score: 610; 24.6% identity (58.8% similar) in 590 aa overlap (36-607:31-562)
10 20 30 40 50 60
pF1KB5 LVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHVDWFSV
:. :.: .. : :. : :: :
NP_001 MESKGASSCRLLFCLLISATVFRPGLGWYTVNSAYGDTIIIPCRLDVPQ-NLMFGKWKYE
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 HKEKRTLIFRVRQGQGQS----EPGEYGQRLSLQDRGATLALTQVTPQDERIFLCQGKRP
. . ... :.. .: . :: .::.:.. . ::..... .::. :.:.
NP_001 KPDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSE-NYTLSISNARISDEKRFVCMLVTE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 RSQ-EYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
. : ..:.: : .:.: . : . .... .... :.....:: .. ::.::.
NP_001 DNVFEAPTIVKVFKQPSKPEIVSKALFL--ETEQLKKLGDCISEDSYPDGNITWYRNGKV
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 LKEEKNRVHIQSSQTVES-SGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESR
:. .. : : .. .. . :::. : :. . .: : . : : ..: :::.. .:.
NP_001 LHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 EVTVPVFYPTEKVWLEV-EPVGMLKEGDRVEIRCLADGNPPPH---FSISKQNPSTREAE
... ..::::.: ..: : . .:::: . ..::..:::::. : . : . : ..
NP_001 QAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 EETTNDNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAP-E
: .: .:.. .: :.:. .: .::. . . :.:. :. ..:..
NP_001 TYTLTD--------VRRNATGDYKCSLIDKKSMIASTA----ITVHYL-DLSLNPSGEVT
300 310 320 330 340
360 370 380 390 400 410
pF1KB5 RQEGSSLTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSI
:: :..: ..: .:.. :.... :. .: .. .:. . .:.: : ... .
NP_001 RQIGDALPVSCTISASRNATVVWMKDNIR--LRSSP--SFSSLHYQDAGNYVCETALQEV
350 360 370 380 390
420 430 440 450 460 470
pF1KB5 PGLNRTQLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTAS---
::.. . ... . : : . : : .. .. :.. : :.:.:.:...:..:
NP_001 EGLKKRESLTLIVEGKPQI--KMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVIN
400 410 420 430 440 450
480 490 500 510 520
pF1KB5 EQDQDPQ---RVLSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNT
. ...: : : .....:: .. . ::: :.: . :
NP_001 QTEESPYINGRYYS--KIIISPEE-NVTLTCTAENQLER--------------------T
460 470 480 490
530 540 550 560 570 580
pF1KB5 TTGLSTSTASPHTRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLY-KKGK
...:..:. . ..:. . :: ::...: .:. :....:.:.:: ::.:
NP_001 VNSLNVSANENREKVNDQA---KL---------IVGIVVGLLLAALVAGVVYWLYMKKSK
500 510 520 530 540
590 600 610 620 630 640
pF1KB5 LPCRRSGKQEITLPPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
.. .:. .. ..: :
NP_001 TASKHVNKDLGNMEENKKLEENNHKTEA
550 560 570
>>NP_001618 (OMIM: 601662) CD166 antigen isoform 1 precu (583 aa)
initn: 222 init1: 140 opt: 450 Z-score: 332.4 bits: 71.6 E(85289): 8.9e-12
Smith-Waterman score: 642; 24.6% identity (59.8% similar) in 590 aa overlap (36-607:31-575)
10 20 30 40 50 60
pF1KB5 LVCAFLLAACCCCPRVAGVPGEAEQPAPELVEVEVGSTALLKCGLSQSQGNLSHVDWFSV
:. :.: .. : :. : :: :
NP_001 MESKGASSCRLLFCLLISATVFRPGLGWYTVNSAYGDTIIIPCRLDVPQ-NLMFGKWKYE
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 HKEKRTLIFRVRQGQGQS----EPGEYGQRLSLQDRGATLALTQVTPQDERIFLCQGKRP
. . ... :.. .: . :: .::.:.. . ::..... .::. :.:.
NP_001 KPDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSE-NYTLSISNARISDEKRFVCMLVTE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 RSQ-EYRIQLRVYKAPEEPNIQVNPLGIPVNSKEPEEVATCVGRNGYPIPQVIWYKNGRP
. : ..:.: : .:.: . : . .... .... :.....:: .. ::.::.
NP_001 DNVFEAPTIVKVFKQPSKPEIVSKALFL--ETEQLKKLGDCISEDSYPDGNITWYRNGKV
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 LKEEKNRVHIQSSQTVES-SGLYTLQSILKAQLVKEDKDAQFYCELNYRLPSGNHMKESR
:. .. : : .. .. . :::. : :. . .: : . : : ..: :::.. .:.
NP_001 LHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 EVTVPVFYPTEKVWLEV-EPVGMLKEGDRVEIRCLADGNPPPH---FSISKQNPSTREAE
... ..::::.: ..: : . .:::: . ..::..:::::. : . : . : ..
NP_001 QAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB5 EETTNDNGVLVLEPARKEHSGRYECQGLDLDTMISLLSEPQELLVNYVSDVRVSPAAP-E
: .: .:.. .: :.:. .: .::. . . :.:. :. ..:..
NP_001 TYTLTD--------VRRNATGDYKCSLIDKKSMIASTA----ITVHYL-DLSLNPSGEVT
300 310 320 330 340
360 370 380 390 400 410
pF1KB5 RQEGSSLTLTCEAESSQDLEFQWLREETGQVLERGPVLQLHDLKREAGGGYRCVASVPSI
:: :..: ..: .:.. :.... :. .: .. .:. . .:.: : ... .
NP_001 RQIGDALPVSCTISASRNATVVWMKDNIR--LRSSP--SFSSLHYQDAGNYVCETALQEV
350 360 370 380 390
420 430 440 450 460 470
pF1KB5 PGLNRTQLVNVAIFGPPWMAFKERKVWVKENMVLNLSCEASGHPRPTISWNVNGTAS---
::.. . ... . : : . : : .. .. :.. : :.:.:.:...:..:
NP_001 EGLKKRESLTLIVEGKPQI--KMTKKTDPSGLSKTIICHVEGFPKPAIQWTITGSGSVIN
400 410 420 430 440 450
480 490 500 510 520
pF1KB5 EQDQDPQ---RVLSTLNVLVTPELLETGVECTASNDLGKNTSILFLELVNLTTLTPDSNT
. ...: : : .....:: .. . ::: :.: .... : . ... :.
NP_001 QTEESPYINGRYYS--KIIISPEE-NVTLTCTAENQLERTVNSLNVSAISI----PE---
460 470 480 490 500
530 540 550 560 570 580
pF1KB5 TTGLSTSTASPHTRANSTSTERKLPEPESRGVVIVAVIVCILVLAVLGAVLYFLY-KKGK
: .:. : : . . .... .::...: .:. :....:.:.:: ::.:
NP_001 -----------HDEADEISDENR-EKVNDQAKLIVGIVVGLLLAALVAGVVYWLYMKKSK
510 520 530 540 550
590 600 610 620 630 640
pF1KB5 LPCRRSGKQEITLPPSRKSELVVEVKSDKLPEEMGLLQGSSGDKRAPGDQGEKYIDLRH
.. .:. .. ..: :
NP_001 TASKHVNKDLGNMEENKKLEENNHKTEA
560 570 580
646 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:30:14 2016 done: Fri Nov 4 21:30:16 2016
Total Scan time: 12.330 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]