Result of FASTA (omim) for pF1KB5019
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5019, 505 aa
  1>>>pF1KB5019 505 - 505 aa - 505 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5742+/-0.000393; mu= 16.8718+/- 0.025
 mean_var=76.0123+/-14.463, 0's: 0 Z-trim(112.1): 43  B-trim: 42 in 1/54
 Lambda= 0.147107
 statistics sampled from 20886 (20929) to 20886 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.245), width:  16
 Scan time:  8.140

The best scores are:                                      opt bits E(85289)
NP_005304 (OMIM: 602046) protein disulfide-isomera ( 505) 3347 720.2 3.4e-207
NP_006840 (OMIM: 608012) protein disulfide-isomera ( 525)  722 163.1 1.8e-39
NP_000909 (OMIM: 112240,176790) protein disulfide- ( 508)  643 146.3 1.9e-34
NP_001269635 (OMIM: 611099) protein disulfide-isom ( 445)  312 76.1 2.4e-13
NP_001269634 (OMIM: 611099) protein disulfide-isom ( 488)  312 76.1 2.6e-13
NP_001269633 (OMIM: 611099) protein disulfide-isom ( 492)  312 76.1 2.6e-13
XP_011508610 (OMIM: 611099) PREDICTED: protein dis ( 402)  310 75.6   3e-13
NP_005733 (OMIM: 611099) protein disulfide-isomera ( 440)  310 75.6 3.2e-13
NP_001269636 (OMIM: 611099) protein disulfide-isom ( 437)  308 75.2 4.3e-13
XP_011524337 (OMIM: 616102) PREDICTED: protein dis ( 229)  297 72.7 1.3e-12
XP_011524336 (OMIM: 616102) PREDICTED: protein dis ( 231)  297 72.7 1.3e-12
NP_061895 (OMIM: 616102) protein disulfide-isomera ( 454)  299 73.3 1.7e-12
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432)  281 69.5 2.3e-11
NP_006801 (OMIM: 616942) protein disulfide-isomera ( 519)  257 64.4   9e-10
NP_055866 (OMIM: 609170) endoplasmic reticulum res ( 406)  254 63.7 1.1e-09
NP_001258510 (OMIM: 607987) dnaJ homolog subfamily ( 747)  230 58.8 6.5e-08
NP_061854 (OMIM: 607987) dnaJ homolog subfamily C  ( 793)  230 58.8 6.8e-08
NP_110382 (OMIM: 610527) thioredoxin-related trans ( 280)  214 55.1   3e-07
XP_006724289 (OMIM: 609063,616811) PREDICTED: thio ( 166)  204 52.9 8.6e-07
NP_036605 (OMIM: 609063,616811) thioredoxin, mitoc ( 166)  204 52.9 8.6e-07
XP_005261565 (OMIM: 609063,616811) PREDICTED: thio ( 197)  204 52.9 9.9e-07
NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 i ( 604)  209 54.3 1.2e-06
NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isof ( 747)  209 54.3 1.4e-06
NP_001139021 (OMIM: 616412) thioredoxin domain-con ( 324)  182 48.4 3.8e-05
NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 prec ( 698)  179 47.9 0.00011
NP_003320 (OMIM: 187700) thioredoxin isoform 1 [Ho ( 105)  155 42.4  0.0008


>>NP_005304 (OMIM: 602046) protein disulfide-isomerase A  (505 aa)
 initn: 3347 init1: 3347 opt: 3347  Z-score: 3840.8  bits: 720.2 E(85289): 3.4e-207
Smith-Waterman score: 3347; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:1-505)

               10        20        30        40        50        60
pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 KRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 ADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 NYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 FGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 VASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 LKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 EKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYL
              430       440       450       460       470       480

              490       500     
pF1KB5 QREATNPPVIQEEKPKKKKKAQEDL
       :::::::::::::::::::::::::
NP_005 QREATNPPVIQEEKPKKKKKAQEDL
              490       500     

>>NP_006840 (OMIM: 608012) protein disulfide-isomerase A  (525 aa)
 initn: 643 init1: 244 opt: 722  Z-score: 829.7  bits: 163.1 E(85289): 1.8e-39
Smith-Waterman score: 722; 30.1% identity (61.7% similar) in 465 aa overlap (48-501:62-508)

        20        30        40        50        60        70       
pF1KB5 AARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKG-
                                     .::::.:::::::. :::::  ::. : . 
NP_006 EPPEEEIPKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAE
              40        50        60        70        80        90 

           80        90       100       110         120       130  
pF1KB5 --IVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--YDGPRTADGIVSHLKKQA
         .: :::::  :. .  ...::. :::::.::.:...    : ::: :.::.  :....
NP_006 SMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRV
             100       110       120       130       140       150 

            140       150       160       170       180       190  
pF1KB5 GPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESL
       ::... :. :   . .:. .:  ..:::.:  .:  . ::  :..  : . :. :.   :
NP_006 GPSAMRLEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALAQDALD-MTFGLTDRPRL
             160       170       180       190        200       210

            200       210       220          230        240        
pF1KB5 VNEYDDNGEGIILFRPSHLTNKFEDKTVAYT---EQKMTSGKIKKF-IQENIFGICPHMT
        ...  . . ..::.      ::..  . .    :  .  : ...: . ...  .    .
NP_006 FQQFGLTKDTVVLFK------KFDEGRADFPVDEELGLDLGDLSRFLVTHSMRLVTEFNS
              220             230       240       250       260    

      250       260       270       280       290       300        
pF1KB5 EDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFS
       . .  .. ..  .. .  .  ...  .          .: .:   :. :  .:       
NP_006 QTSAKIFAAR--ILNHLLLFVNQTLAAHRELLAGFGEAAPRF--RGQVLFVVVDVAADNE
          270         280       290       300         310       320

      310       320        330       340       350       360       
pF1KB5 HELSDFGLESTAGE-IPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKS
       : :. :::.. :.  . .: ..:.:  :..  .     . ..  : .  ..:..: :: :
NP_006 HVLQYFGLKAEAAPTLRLVNLETTK--KYAPVDGGPVTAASITAFCHAVLNGQVKPYLLS
              330       340         350       360       370        

       370        380       390       400       410       420      
pF1KB5 EPIPESNDG-PVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD
       . :: . :  :::..:..::.... .:.:.:...:::::: :::.. : .. :.:: .  
NP_006 QEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDH
      380       390       400       410       420       430        

        430       440       450       460       470       480      
pF1KB5 PNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATN
        .:.::..:::::.. . . :.::::. . ::.   .  .:.. :.:  : ..:.    :
NP_006 EDIIIAELDATANELDA-FAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLD----N
      440       450        460       470       480       490       

        490       500                  
pF1KB5 PPVIQEEKPKKKKKAQEDL             
         :.  :.: ..  :                 
NP_006 GGVLPTEEPPEEPAAPFPEPPANSTMGSKEEL
           500       510       520     

>>NP_000909 (OMIM: 112240,176790) protein disulfide-isom  (508 aa)
 initn: 675 init1: 280 opt: 643  Z-score: 739.3  bits: 146.3 E(85289): 1.9e-34
Smith-Waterman score: 853; 34.7% identity (63.5% similar) in 498 aa overlap (3-481:2-471)

               10        20        30        40        50        60
pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC
         :::  :  .:: :. :      . :: :  .::   ..   .   .::::.:::::::
NP_000  MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALA---AHKYLLVEFYAPWCGHC
                10        20        30           40        50      

               70           80        90       100       110       
pF1KB5 KRLAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA--Y
       : :::::  :: .::.    . ::::: : ...  ..::: ::::.:.::.:. :.   :
NP_000 KALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEY
         60        70        80        90       100       110      

         120       130       140       150       160       170     
pF1KB5 DGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAA
        . : :: ::. :::..:::.. :      .... .......::: :  :.. ..::.::
NP_000 TAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAA
        120       130       140       150       160       170      

         180       190       200       210       220       230     
pF1KB5 SNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKF
         . :.  :. :.  .. ..:. . .:..::.      ::..    . : ..:. ..  :
NP_000 EAI-DDIPFGITSNSDVFSKYQLDKDGVVLFK------KFDEGRNNF-EGEVTKENLLDF
         180       190       200             210        220        

         240       250            260        270             280   
pF1KB5 IQENIFGICPHMTEDNKDLIQGKD-----LLIAYYDV-DYEKNAKGSNY------WRNRV
       :..: . .  ..::..   : : .     ::.   .: ::  ..: ::.      .....
NP_000 IKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDY--DGKLSNFKTAAESFKGKI
      230       240       250       260         270       280      

           290       300       310       320       330       340   
pF1KB5 MMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFS
       ...   :.:. :  :  .         :  :::..   : :.: . : . :   .. :  
NP_000 LFI---FIDSDHTDNQRI---------LEFFGLKKE--ECPAVRLITLEEEMTKYKPESE
           290       300                310         320       330  

            350       360       370        380       390       400 
pF1KB5 R-DGKALERFLQDYFDGNLKRYLKSEPIPESNDG-PVKVVVAENFDEIVNNENKDVLIEF
       .  .. . .: . ...:..: .: :. .::. :  ::::.:..::.... .:.:.:..::
NP_000 ELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAFDEKKNVFVEF
            340       350       360       370       380       390  

             410       420       430       440       450       460 
pF1KB5 YAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKK
       :::::::::.: : . .:::  .   ::::::::.:::.: .  .:..:::. : ::.  
NP_000 YAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEA-VKVHSFPTLKFFPASAD
            400       410       420       430        440       450 

             470       480       490       500                  
pF1KB5 LNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL             
        .   :.: : :. : ..:.                                     
NP_000 RTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDDDQKAVKDEL
             460       470       480       490       500        

>>NP_001269635 (OMIM: 611099) protein disulfide-isomeras  (445 aa)
 initn: 423 init1: 249 opt: 312  Z-score: 360.5  bits: 76.1 E(85289): 2.4e-13
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:162-333)

                        10        20        30        40        50 
pF1KB5          MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
                                     .. .::.:::::.:.. . :  :  . .::
NP_001 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
             140       150       160       170       180           

              60        70            80        90       100       
pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
       :.:::::::: : ::. :::...:    : : :: :: :.:    ..::. :.::.:::.
NP_001 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
     190       200       210       220       230       240         

       110       120           130        140       150       160  
pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
        ::    ::: :: . :::.    .. .: :  .  . .:.  :.   ...  .:. .  
NP_001 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
     250       260       270       280       290       300         

               170       180       190       200       210         
pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
         :. . ... .:..  .: :.:.                                    
NP_001 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
     310       320       330       340       350       360         

>--
 initn: 278 init1: 249 opt: 312  Z-score: 360.5  bits: 76.1 E(85289): 2.4e-13
Smith-Waterman score: 312; 43.2% identity (73.6% similar) in 125 aa overlap (6-125:7-129)

                10           20         30        40        50     
pF1KB5  MRLRRLALFPGVA---LLLAAARLAAASD-VLELTDDNFESRISDTGSAGLMLVEFFAP
             .:  ::..   ..::.  : ..:: :.::: .::. .. .. :  : ::::.::
NP_001 MYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDS--LWLVEFYAP
               10        20        30        40          50        

          60        70        80        90       100       110     
pF1KB5 WCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA-
       :::::.::.::.. ::: :: .: .. ::   . .  ..:::.:.::.::: ....    
NP_001 WCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPED
       60        70        80        90       100       110        

          120       130       140       150       160       170    
pF1KB5 YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKA
       :.: ::...::                                                 
NP_001 YQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKN
      120       130       140       150       160       170        

>>NP_001269634 (OMIM: 611099) protein disulfide-isomeras  (488 aa)
 initn: 423 init1: 249 opt: 312  Z-score: 359.9  bits: 76.1 E(85289): 2.6e-13
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:205-376)

                        10        20        30        40        50 
pF1KB5          MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
                                     .. .::.:::::.:.. . :  :  . .::
NP_001 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
          180       190       200       210       220         230  

              60        70            80        90       100       
pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
       :.:::::::: : ::. :::...:    : : :: :: :.:    ..::. :.::.:::.
NP_001 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
            240       250       260       270       280       290  

       110       120           130        140       150       160  
pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
        ::    ::: :: . :::.    .. .: :  .  . .:.  :.   ...  .:. .  
NP_001 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
            300       310       320       330       340       350  

               170       180       190       200       210         
pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
         :. . ... .:..  .: :.:.                                    
NP_001 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
            360       370       380       390       400       410  

>--
 initn: 254 init1: 249 opt: 312  Z-score: 359.9  bits: 76.1 E(85289): 2.6e-13
Smith-Waterman score: 312; 43.2% identity (73.6% similar) in 125 aa overlap (6-125:50-172)

                                        10           20         30 
pF1KB5                          MRLRRLALFPGVA---LLLAAARLAAASD-VLELT
                                     .:  ::..   ..::.  : ..:: :.:::
NP_001 ILARRSDRGSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELT
      20        30        40        50        60        70         

              40        50        60        70        80        90 
pF1KB5 DDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNT
        .::. .. .. :  : ::::.:::::::.::.::.. ::: :: .: .. ::   . . 
NP_001 PSNFNREVIQSDS--LWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSL
      80        90         100       110       120       130       

             100       110        120       130       140       150
pF1KB5 CNKYGVSGYPTLKIFRDGEEAGA-YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFIS
        ..:::.:.::.::: ....    :.: ::...::                         
NP_001 GGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSG
       140       150       160       170       180       190       

              160       170       180       190       200       210
pF1KB5 DKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSH
                                                                   
NP_001 KQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKE
       200       210       220       230       240       250       

>>NP_001269633 (OMIM: 611099) protein disulfide-isomeras  (492 aa)
 initn: 423 init1: 249 opt: 312  Z-score: 359.8  bits: 76.1 E(85289): 2.6e-13
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:209-380)

                        10        20        30        40        50 
pF1KB5          MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
                                     .. .::.:::::.:.. . :  :  . .::
NP_001 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
      180       190       200       210       220         230      

              60        70            80        90       100       
pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
       :.:::::::: : ::. :::...:    : : :: :: :.:    ..::. :.::.:::.
NP_001 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
        240       250       260       270       280       290      

       110       120           130        140       150       160  
pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
        ::    ::: :: . :::.    .. .: :  .  . .:.  :.   ...  .:. .  
NP_001 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
        300       310       320       330       340       350      

               170       180       190       200       210         
pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
         :. . ... .:..  .: :.:.                                    
NP_001 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
        360       370       380       390       400       410      

>--
 initn: 249 init1: 249 opt: 312  Z-score: 359.8  bits: 76.1 E(85289): 2.6e-13
Smith-Waterman score: 312; 43.2% identity (73.6% similar) in 125 aa overlap (6-125:54-176)

                                        10           20         30 
pF1KB5                          MRLRRLALFPGVA---LLLAAARLAAASD-VLELT
                                     .:  ::..   ..::.  : ..:: :.:::
NP_001 NISSDFQPCSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELT
            30        40        50        60        70        80   

              40        50        60        70        80        90 
pF1KB5 DDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNT
        .::. .. .. :  : ::::.:::::::.::.::.. ::: :: .: .. ::   . . 
NP_001 PSNFNREVIQSDS--LWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSL
            90         100       110       120       130       140 

             100       110        120       130       140       150
pF1KB5 CNKYGVSGYPTLKIFRDGEEAGA-YDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFIS
        ..:::.:.::.::: ....    :.: ::...::                         
NP_001 GGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSG
             150       160       170       180       190       200 

              160       170       180       190       200       210
pF1KB5 DKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSH
                                                                   
NP_001 KQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKE
             210       220       230       240       250       260 

>>XP_011508610 (OMIM: 611099) PREDICTED: protein disulfi  (402 aa)
 initn: 423 init1: 249 opt: 310  Z-score: 358.8  bits: 75.6 E(85289): 3e-13
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:157-328)

                        10        20        30        40        50 
pF1KB5          MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
                                     .. .::.:::::.:.. . :  :  . .::
XP_011 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
        130       140       150       160       170         180    

              60        70            80        90       100       
pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
       :.:::::::: : ::. :::...:    : : :: :: :.:    ..::. :.::.:::.
XP_011 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
          190       200       210       220       230       240    

       110       120           130        140       150       160  
pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
        ::    ::: :: . :::.    .. .: :  .  . .:.  :.   ...  .:. .  
XP_011 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
          250       260       270       280       290       300    

               170       180       190       200       210         
pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
         :. . ... .:..  .: :.:.                                    
XP_011 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
          310       320       330       340       350       360    

>--
 initn: 258 init1: 249 opt: 310  Z-score: 358.8  bits: 75.6 E(85289): 3e-13
Smith-Waterman score: 310; 41.3% identity (72.2% similar) in 126 aa overlap (1-125:1-124)

               10        20        30        40        50        60
pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC
       : :  :.:   . .: . .  ....::.::: .::. .. .. :  : ::::.:::::::
XP_011 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDS--LWLVEFYAPWCGHC
               10        20        30        40          50        

               70        80        90       100       110          
pF1KB5 KRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA-YDGPR
       .::.::.. ::: :: .: .. ::   . .  ..:::.:.::.::: ....    :.: :
XP_011 QRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGR
       60        70        80        90       100       110        

     120       130       140       150       160       170         
pF1KB5 TADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLR
       :...::                                                      
XP_011 TGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSE
      120       130       140       150       160       170        

>>NP_005733 (OMIM: 611099) protein disulfide-isomerase A  (440 aa)
 initn: 423 init1: 249 opt: 310  Z-score: 358.3  bits: 75.6 E(85289): 3.2e-13
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:157-328)

                        10        20        30        40        50 
pF1KB5          MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
                                     .. .::.:::::.:.. . :  :  . .::
NP_005 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
        130       140       150       160       170         180    

              60        70            80        90       100       
pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
       :.:::::::: : ::. :::...:    : : :: :: :.:    ..::. :.::.:::.
NP_005 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
          190       200       210       220       230       240    

       110       120           130        140       150       160  
pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
        ::    ::: :: . :::.    .. .: :  .  . .:.  :.   ...  .:. .  
NP_005 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
          250       260       270       280       290       300    

               170       180       190       200       210         
pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
         :. . ... .:..  .: :.:.                                    
NP_005 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
          310       320       330       340       350       360    

>--
 initn: 258 init1: 249 opt: 310  Z-score: 358.3  bits: 75.6 E(85289): 3.2e-13
Smith-Waterman score: 310; 41.3% identity (72.2% similar) in 126 aa overlap (1-125:1-124)

               10        20        30        40        50        60
pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHC
       : :  :.:   . .: . .  ....::.::: .::. .. .. :  : ::::.:::::::
NP_005 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDS--LWLVEFYAPWCGHC
               10        20        30        40          50        

               70        80        90       100       110          
pF1KB5 KRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA-YDGPR
       .::.::.. ::: :: .: .. ::   . .  ..:::.:.::.::: ....    :.: :
NP_005 QRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGR
       60        70        80        90       100       110        

     120       130       140       150       160       170         
pF1KB5 TADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLR
       :...::                                                      
NP_005 TGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSE
      120       130       140       150       160       170        

>>NP_001269636 (OMIM: 611099) protein disulfide-isomeras  (437 aa)
 initn: 423 init1: 249 opt: 308  Z-score: 356.0  bits: 75.2 E(85289): 4.3e-13
Smith-Waterman score: 355; 36.8% identity (64.9% similar) in 174 aa overlap (22-183:154-325)

                        10        20        30        40        50 
pF1KB5          MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVE
                                     .. .::.:::::.:.. . :  :  . .::
NP_001 ALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLD--SEDVWMVE
           130       140       150       160       170         180 

              60        70            80        90       100       
pF1KB5 FFAPWCGHCKRLAPEYEAAATRLK----GIVPLAKVDCTANTNTCNKYGVSGYPTLKIFR
       :.:::::::: : ::. :::...:    : : :: :: :.:    ..::. :.::.:::.
NP_001 FYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQ
             190       200       210       220       230       240 

       110       120           130        140       150       160  
pF1KB5 DGEEAGAYDGPRTADGIVSH----LKKQAGPASV-PLRTEEEFKKFISDKDASIVGFFD-
        ::    ::: :: . :::.    .. .: :  .  . .:.  :.   ...  .:. .  
NP_001 KGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPH
             250       260       270       280       290       300 

               170       180       190       200       210         
pF1KB5 --DSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT
         :. . ... .:..  .: :.:.                                    
NP_001 ILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINA
             310       320       330       340       350       360 

>--
 initn: 278 init1: 249 opt: 308  Z-score: 356.0  bits: 75.2 E(85289): 4.3e-13
Smith-Waterman score: 308; 44.7% identity (75.4% similar) in 114 aa overlap (14-125:10-121)

               10        20         30        40        50         
pF1KB5 MRLRRLALFPGVALLLAAARLAAASD-VLELTDDNFESRISDTGSAGLMLVEFFAPWCGH
                    ..::.  : ..:: :.::: .::. .. .. :  : ::::.::::::
NP_001     MILGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDS--LWLVEFYAPWCGH
                   10        20        30        40          50    

      60        70        80        90       100       110         
pF1KB5 CKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGA-YDGP
       :.::.::.. ::: :: .: .. ::   . .  ..:::.:.::.::: ....    :.: 
NP_001 CQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGG
           60        70        80        90       100       110    

      120       130       140       150       160       170        
pF1KB5 RTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNL
       ::...::                                                     
NP_001 RTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDS
          120       130       140       150       160       170    

>>XP_011524337 (OMIM: 616102) PREDICTED: protein disulfi  (229 aa)
 initn: 251 init1: 134 opt: 297  Z-score: 347.5  bits: 72.7 E(85289): 1.3e-12
Smith-Waterman score: 297; 32.4% identity (62.4% similar) in 173 aa overlap (28-196:28-191)

               10        20        30         40        50         
pF1KB5 MRLRRLALFPGVALLLAAARLAAASDVLELTDDNF-ESRISDTGSAGLMLVEFFAPWCGH
                                  .:  :..: :.: .:     . ::.:.::::::
XP_011 MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDD-----IWLVDFYAPWCGH
               10        20        30        40             50     

      60        70           80        90       100       110      
pF1KB5 CKRLAPEYEAAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYD
       ::.: : .. .. ..:.:   : ..:.: :. ..  ...:: ::::.:... :. :  : 
XP_011 CKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLAYNYR
          60        70        80        90       100        110    

        120       130       140       150       160       170      
pF1KB5 GPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAAS
       :::: : :.   .. .:    :: ... :...  .:   .   .  . :  . ... :::
XP_011 GPRTKDDIIEFAHRVSGALIRPLPSQQMFEHM--QKRHRVFFVYVGGESPLKEKYIDAAS
          120       130       140         150       160       170  

        180       190       200       210       220       230      
pF1KB5 NLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFI
       .:   : .  .  : .: ::                                        
XP_011 ELI-VYTYFFSASEEVVPEYVTLKEMPAVLVFKDETYFVYDDNNYTLMLSYKRYYLHT  
             180       190       200       210       220           




505 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 22:43:17 2016 done: Fri Nov  4 22:43:18 2016
 Total Scan time:  8.140 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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