Result of FASTA (omim) for pF1KB4185
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4185, 385 aa
  1>>>pF1KB4185 385 - 385 aa - 385 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1227+/-0.000398; mu= 12.9663+/- 0.025
 mean_var=86.4529+/-17.276, 0's: 0 Z-trim(113.1): 406  B-trim: 98 in 1/54
 Lambda= 0.137938
 statistics sampled from 21896 (22318) to 21896 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.262), width:  16
 Scan time:  8.390

The best scores are:                                      opt bits E(85289)
NP_003260 (OMIM: 603849) nuclear receptor subfamil ( 385) 2557 519.0 7.6e-147
NP_001273031 (OMIM: 603849) nuclear receptor subfa ( 422) 2505 508.6 1.1e-143
NP_055064 (OMIM: 268100,604485,611131) photorecept ( 410) 1059 220.9 4.4e-57
NP_057430 (OMIM: 268100,604485,611131) photorecept ( 367)  880 185.2 2.1e-46
NP_001278159 (OMIM: 114480,133430,157300,608446,61 ( 597)  574 124.4 6.8e-28
NP_005645 (OMIM: 132890,615722) COUP transcription ( 423)  552 120.0 1.1e-26
XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP ( 273)  541 117.7 3.3e-26
NP_066285 (OMIM: 107773,615779) COUP transcription ( 414)  541 117.8 4.7e-26
NP_005225 (OMIM: 132880) nuclear receptor subfamil ( 404)  540 117.6 5.3e-26
NP_001138629 (OMIM: 107773,615779) COUP transcript ( 261)  532 115.9 1.1e-25
NP_001138628 (OMIM: 107773,615779) COUP transcript ( 261)  532 115.9 1.1e-25
NP_001138627 (OMIM: 107773,615779) COUP transcript ( 281)  532 115.9 1.2e-25
XP_006715438 (OMIM: 114480,133430,157300,608446,61 ( 422)  476 104.9 3.8e-22
NP_000116 (OMIM: 114480,133430,157300,608446,61536 ( 595)  476 104.9   5e-22
NP_001116213 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
NP_001116214 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
XP_011533847 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
XP_011533845 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
XP_016865869 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
XP_016865867 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
XP_016865868 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
XP_016865866 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
NP_001116212 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
XP_016865870 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
XP_016865865 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
XP_011533846 (OMIM: 114480,133430,157300,608446,61 ( 595)  476 104.9   5e-22
NP_001315029 (OMIM: 114480,133430,157300,608446,61 ( 310)  437 97.0 6.3e-20
XP_006715437 (OMIM: 114480,133430,157300,608446,61 ( 466)  437 97.1 8.9e-20
XP_011533849 (OMIM: 114480,133430,157300,608446,61 ( 483)  437 97.1 9.2e-20
NP_001165290 (OMIM: 600409) peroxisome proliferato ( 402)  431 95.9 1.8e-19
XP_006715186 (OMIM: 600409) PREDICTED: peroxisome  ( 441)  431 95.9 1.9e-19
XP_006715183 (OMIM: 600409) PREDICTED: peroxisome  ( 441)  431 95.9 1.9e-19
XP_011513012 (OMIM: 600409) PREDICTED: peroxisome  ( 441)  431 95.9 1.9e-19
XP_016866460 (OMIM: 600409) PREDICTED: peroxisome  ( 441)  431 95.9 1.9e-19
NP_006229 (OMIM: 600409) peroxisome proliferator-a ( 441)  431 95.9 1.9e-19
XP_016866463 (OMIM: 600409) PREDICTED: peroxisome  ( 441)  431 95.9 1.9e-19
XP_016866461 (OMIM: 600409) PREDICTED: peroxisome  ( 441)  431 95.9 1.9e-19
XP_016866462 (OMIM: 600409) PREDICTED: peroxisome  ( 441)  431 95.9 1.9e-19
NP_001165289 (OMIM: 600409) peroxisome proliferato ( 441)  431 95.9 1.9e-19
XP_005249250 (OMIM: 600409) PREDICTED: peroxisome  ( 441)  431 95.9 1.9e-19
XP_011513009 (OMIM: 600409) PREDICTED: peroxisome  ( 441)  431 95.9 1.9e-19
XP_011513011 (OMIM: 600409) PREDICTED: peroxisome  ( 441)  431 95.9 1.9e-19
NP_001001928 (OMIM: 170998) peroxisome proliferato ( 468)  425 94.7 4.7e-19
XP_006724333 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  425 94.7 4.7e-19
XP_005261713 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  425 94.7 4.7e-19
XP_011528544 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  425 94.7 4.7e-19
XP_011528543 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  425 94.7 4.7e-19
XP_006724332 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  425 94.7 4.7e-19
XP_011528545 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  425 94.7 4.7e-19
NP_005027 (OMIM: 170998) peroxisome proliferator-a ( 468)  425 94.7 4.7e-19


>>NP_003260 (OMIM: 603849) nuclear receptor subfamily 2   (385 aa)
 initn: 2557 init1: 2557 opt: 2557  Z-score: 2757.4  bits: 519.0 E(85289): 7.6e-147
Smith-Waterman score: 2557; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385)

               10        20        30        40        50        60
pF1KB4 MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 PVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEENGAAAHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEENGAAAHF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 PSAALPAPAFFTAVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PSAALPAPAFFTAVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 ATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDAN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 TLLAVSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TLLAVSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 SGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEE
              310       320       330       340       350       360

              370       380     
pF1KB4 VFFKKTIGNVPITRLLSDMYKSSDI
       :::::::::::::::::::::::::
NP_003 VFFKKTIGNVPITRLLSDMYKSSDI
              370       380     

>>NP_001273031 (OMIM: 603849) nuclear receptor subfamily  (422 aa)
 initn: 2501 init1: 2501 opt: 2505  Z-score: 2700.8  bits: 508.6 E(85289): 1.1e-143
Smith-Waterman score: 2505; 98.2% identity (99.0% similar) in 385 aa overlap (1-385:41-422)

                                             10        20        30
pF1KB4                               MSKPAGSTSRILDIPCKVCGDRSSGKHYGV
                                     . .:.:   :::::::::::::::::::::
NP_001 KEPSPRPECRADPGPGLGFPLGSGLPWPSLLESPGG---RILDIPCKVCGDRSSGKHYGV
               20        30        40           50        60       

               40        50        60        70        80        90
pF1KB4 YACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQH
        70        80        90       100       110       120       

              100       110       120       130       140       150
pF1KB4 ERGPRTSTIRKQVALYFRGHKEENGAAAHFPSAALPAPAFFTAVTQLEPHGLELAAVSTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERGPRTSTIRKQVALYFRGHKEENGAAAHFPSAALPAPAFFTAVTQLEPHGLELAAVSTT
       130       140       150       160       170       180       

              160       170       180       190       200       210
pF1KB4 PERQTLVSLAQPTPKYPHEVNGTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PERQTLVSLAQPTPKYPHEVNGTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTLS
       190       200       210       220       230       240       

              220       230       240       250       260       270
pF1KB4 LQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNKIISEIQALQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNKIISEIQALQE
       250       260       270       280       290       300       

              280       290       300       310       320       330
pF1KB4 VVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTLNSYIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTLNSYIH
       310       320       330       340       350       360       

              340       350       360       370       380     
pF1KB4 TRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI
       370       380       390       400       410       420  

>>NP_055064 (OMIM: 268100,604485,611131) photoreceptor-s  (410 aa)
 initn: 1058 init1: 377 opt: 1059  Z-score: 1145.8  bits: 220.9 E(85289): 4.4e-57
Smith-Waterman score: 1059; 44.1% identity (70.7% similar) in 392 aa overlap (4-382:38-410)

                                          10        20        30   
pF1KB4                            MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYAC
                                     :.: .    .. :.:::: :::::::.:::
NP_055 LMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSP---SLQCRVCGDSSSGKHYGIYAC
        10        20        30        40           50        60    

            40        50        60        70        80        90   
pF1KB4 DGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHERG
       .:::::::::.::   : :. :  : :::::.:::::.::::::::...::.::::.:: 
NP_055 NGCSGFFKRSVRRRLIYRCQVGA-GMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQ
           70        80         90       100       110       120   

           100        110          120        130       140        
pF1KB4 PRTSTIRKQVAL-YFRGHKE---ENGAAAHFPSAALP-APAFFTAVTQLEPHGLELAAVS
       ::...   :: :  .... :   :. .:   :..  : .:. ..:.  :  : .    ..
NP_055 PRSTA---QVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
              130       140       150       160       170       180

      150             160         170       180       190       200
pF1KB4 TT-----PERQTL-VSLAQPTPKYPHE--VNGTPMYLYEVATESVCESAARLLFMSIKWA
        :     ::     .....  :..:     ...:  :     .:. :..::::::..:::
NP_055 ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGL-----DSIHETSARLLFMAVKWA
              190       200       210            220       230     

              210       220       230       240       250       260
pF1KB4 KSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNK
       :..:.::.: ..::..:::.:: :::.::  ::..:.:.  :::    .. .  . .:. 
NP_055 KNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTL
         240       250       260       270       280       290     

              270       280       290       300       310       320
pF1KB4 IISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDE
          : ..:::...::: : .: :::::.: .: ::  :     : :....   . ::::.
NP_055 ASMETRVLQETISRFRALAVDPTEFACMKALVLFK--P-----ETRGLKDPEHVEALQDQ
         300       310       320       330              340        

              330       340       350       360       370       380
pF1KB4 AQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMY
       .:. :... ....:.:: ::::::::::.:: :.   :: .::.:::::.:. .:: ::.
NP_055 SQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMF
      350       360       370       380       390       400        

            
pF1KB4 KSSDI
       :.   
NP_055 KN   
      410   

>>NP_057430 (OMIM: 268100,604485,611131) photoreceptor-s  (367 aa)
 initn: 874 init1: 377 opt: 880  Z-score: 954.1  bits: 185.2 E(85289): 2.1e-46
Smith-Waterman score: 880; 41.8% identity (69.1% similar) in 349 aa overlap (4-339:38-367)

                                          10        20        30   
pF1KB4                            MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYAC
                                     :.: .    .. :.:::: :::::::.:::
NP_057 LMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSP---SLQCRVCGDSSSGKHYGIYAC
        10        20        30        40           50        60    

            40        50        60        70        80        90   
pF1KB4 DGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHERG
       .:::::::::.::   : :. :  : :::::.:::::.::::::::...::.::::.:: 
NP_057 NGCSGFFKRSVRRRLIYRCQVGA-GMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQ
           70        80         90       100       110       120   

           100        110          120        130       140        
pF1KB4 PRTSTIRKQVAL-YFRGHKE---ENGAAAHFPSAALP-APAFFTAVTQLEPHGLELAAVS
       ::...   :: :  .... :   :. .:   :..  : .:. ..:.  :  : .    ..
NP_057 PRSTA---QVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
              130       140       150       160       170       180

      150             160         170       180       190       200
pF1KB4 TT-----PERQTL-VSLAQPTPKYPHE--VNGTPMYLYEVATESVCESAARLLFMSIKWA
        :     ::     .....  :..:     ...:  :     .:. :..::::::..:::
NP_057 ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGL-----DSIHETSARLLFMAVKWA
              190       200       210            220       230     

              210       220       230       240       250       260
pF1KB4 KSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNK
       :..:.::.: ..::..:::.:: :::.::  ::..:.:.  :::    .. .  . .:. 
NP_057 KNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTL
         240       250       260       270       280       290     

              270       280       290       300       310       320
pF1KB4 IISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDE
          : ..:::...::: : .: :::::.: .: ::  :     : :....   . ::::.
NP_057 ASMETRVLQETISRFRALAVDPTEFACMKALVLFK--P-----ETRGLKDPEHVEALQDQ
         300       310       320       330              340        

              330       340       350       360       370       380
pF1KB4 AQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMY
       .:. :... ....:.:: :                                         
NP_057 SQVMLSQHSKAHHPSQPVR                                         
      350       360                                                

>>NP_001278159 (OMIM: 114480,133430,157300,608446,615363  (597 aa)
 initn: 474 init1: 287 opt: 574  Z-score: 621.8  bits: 124.4 E(85289): 6.8e-28
Smith-Waterman score: 574; 32.4% identity (60.9% similar) in 373 aa overlap (16-379:185-545)

                              10        20        30        40     
pF1KB4                MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIR
                                     : ::.: .:: ::::..:.::..::::::.
NP_001 DNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQ
          160       170       180       190       200       210    

            50        60        70        80        90        100  
pF1KB4 RNR--TYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHER-GPRTSTIRKQ
        ::   :.: . ::  : .::..:..:.::::.:: ::.: : .....: : :    ..:
NP_001 GNRHNDYMCPATNQ--CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQ
          220         230       240       250       260       270  

            110        120        130       140       150       160
pF1KB4 VALYFRGH-KEENGAAAHFPSAAL-PAPAFFTAVTQLEPHGLELAAVSTTPERQTLVSLA
             :. . : :.:. . .: : :.: .   . . . ..:   :.: : .... . : 
NP_001 RD---DGEGRGEVGSAGDMRAANLWPSPLM---IKRSKKNSL---ALSLTADQMVSALLD
               280       290          300          310       320   

              170       180       190       200       210       220
pF1KB4 QPTPKYPHEVNGTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLED
          :    : . :  .        . . : : :   :.::: ::.:  :.:.::. ::: 
NP_001 AEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLEC
           330       340       350       360       370       380   

              230       240       250       260       270       280
pF1KB4 AWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRL
       :: :....:.. :      . :: . ..  : .... .. ..  .. :  . .:::.. :
NP_001 AWLEILMIGLV-WRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNL
           390        400       410       420       430       440  

              290        300       310       320       330         
pF1KB4 DATEFACLKCIVTFKA-VPTHSGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPT---Q
       .. ::.::: :. ... : :  .: :.:...   :  . :.   ::   .     :   :
NP_001 QGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQ
            450       460       470       480       490       500  

        340       350       360       370       380                
pF1KB4 PCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI           
         :...:::.:  .: .: . .:...  :  . ::.  :: .:                 
NP_001 HQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASV
            510       520       530       540       550       560  

NP_001 EETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
            570       580       590       

>>NP_005645 (OMIM: 132890,615722) COUP transcription fac  (423 aa)
 initn: 951 init1: 302 opt: 552  Z-score: 600.4  bits: 120.0 E(85289): 1.1e-26
Smith-Waterman score: 880; 38.1% identity (65.5% similar) in 383 aa overlap (4-382:74-409)

                                          10        20        30   
pF1KB4                            MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYAC
                                     : :: .    : : ::::.::::::: ..:
NP_005 AGSGAPHTPQTPGQPGAPATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTC
            50        60        70        80        90       100   

            40        50        60        70        80        90   
pF1KB4 DGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHERG
       .::..:::::.::: ::.:...   .::.:. :::::. :::::::.:.: ..:::. : 
NP_005 EGCKSFFKRSVRRNLTYTCRANR--NCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRM
           110       120         130       140       150       160 

           100           110       120       130       140         
pF1KB4 PRTSTIRKQVALY----FRGHKEENGAAAHFPSAALPAPAFFTAVTQLEPHGLELAAVST
       : :.    : ::     . ::   .:              ... . . ::.         
NP_005 PPTQPNPGQYALTNGDPLNGHCYLSG--------------YISLLLRAEPY---------
             170       180                     190                 

     150       160       170       180       190       200         
pF1KB4 TPERQTLVSLAQPTPKYPHEVNGTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTL
                   :: .:  .    :  .. .  :..:: :::::: ...::...: :  :
NP_005 ------------PTSRYGSQCM-QPNNIMGI--ENICELAARLLFSAVEWARNIPFFPDL
                  200        210         220       230       240   

     210       220       230       240       250       260         
pF1KB4 SLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNKIISEIQALQ
       .. ::. ::. .: :::::. :: ..:. .  :::..:....  .....  ....:. .:
NP_005 QITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQ
           250       260       270       280       290       300   

     270       280       290       300       310       320         
pF1KB4 EVVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTLNSYI
       : : ... :..:..:..::: :: :        :.  .. .:: : .::...: .:. :.
NP_005 EQVEKLKALHVDSAEYSCLKAIVLFT-------SDACGLSDAAHIESLQEKSQCALEEYV
           310       320              330       340       350      

     330       340       350       360       370       380         
pF1KB4 HTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI    
       ...::.:: ::::::: ::.::..: :.::..:: . .:..::  :. ::  :       
NP_005 RSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWP
        360       370       380       390       400       410      

NP_005 YMSIQCS
        420   

>>XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP tra  (273 aa)
 initn: 564 init1: 302 opt: 541  Z-score: 591.4  bits: 117.7 E(85289): 3.3e-26
Smith-Waterman score: 541; 38.5% identity (72.4% similar) in 221 aa overlap (162-382:49-259)

             140       150       160       170       180       190 
pF1KB4 TAVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYEVATESVCESAAR
                                     :: .:  .    :  .. .  :..:: :::
XP_016 GQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCM-QPNNIMGI--ENICELAAR
       20        30        40        50         60          70     

             200       210       220       230       240       250 
pF1KB4 LLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGD
       ::: ...::...: :  :.. ::. ::. .: :::::. :: ..:. .  :::..:....
XP_016 LLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHAS
          80        90       100       110       120       130     

             260       270       280       290       300       310 
pF1KB4 NTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNA
         .....  ....:. .:: : ... :..:..:..::: :: :        :.  .. .:
XP_016 PMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFT-------SDACGLSDA
         140       150       160       170              180        

             320       330       340       350       360       370 
pF1KB4 AAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVP
       : : .::...: .:. :....::.:: ::::::: ::.::..: :.::..:: . .:..:
XP_016 AHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTP
      190       200       210       220       230       240        

             380                
pF1KB4 ITRLLSDMYKSSDI           
       :  :. ::  :              
XP_016 IETLIRDMLLSGSSFNWPYMSIQCS
      250       260       270   

>>NP_066285 (OMIM: 107773,615779) COUP transcription fac  (414 aa)
 initn: 924 init1: 312 opt: 541  Z-score: 588.7  bits: 117.8 E(85289): 4.7e-26
Smith-Waterman score: 863; 37.7% identity (67.2% similar) in 369 aa overlap (14-382:77-402)

                                10        20        30        40   
pF1KB4                  MSKPAGSTSRILDIPCKVCGDRSSGKHYGVYACDGCSGFFKRS
                                     : : ::::.::::::: ..:.::..:::::
NP_066 GPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRS
         50        60        70        80        90       100      

            50        60        70        80        90       100   
pF1KB4 IRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHERGPRTSTIRKQV
       .::: .:.:... .  ::.:. :::::. :::::::.:.: ..:::. : : :.  . : 
NP_066 VRRNLSYTCRANRN--CPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQF
        110       120         130       140       150       160    

           110       120       130       140       150       160   
pF1KB4 ALYFRGHKEENGAAAHFPSAALPAPAFFTAVTQLEPHGLELAAVSTTPERQTLVSLAQPT
       ::        ::   .  :      .... . . ::.          :  .   .  :: 
NP_066 AL-------TNGDPLNCHSYL---SGYISLLLRAEPY----------PTSRFGSQCMQP-
                 170          180       190                 200    

           170       180       190       200       210       220   
pF1KB4 PKYPHEVNGTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWR
           ... :          :..:: :::.:: ...::...: :  :.. ::. ::. .: 
NP_066 ----NNIMGI---------ENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWS
                        210       220       230       240       250

           230       240       250       260       270       280   
pF1KB4 ELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDAT
       :::::. :: ..:. .  :::..:....  .....  ....:. .:: : ... :..:..
NP_066 ELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSA
              260       270       280       290       300       310

           290       300       310       320       330       340   
pF1KB4 EFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKL
       :..::: :: :        :.  .. ..: . .::...: .:. :....::.:: :::::
NP_066 EYSCLKAIVLFT-------SDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKL
              320              330       340       350       360   

           350       360       370       380              
pF1KB4 LLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI         
       :: ::.::..: :.::..:: . .:..::  :. ::  :            
NP_066 LLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
           370       380       390       400       410    

>>NP_005225 (OMIM: 132880) nuclear receptor subfamily 2   (404 aa)
 initn: 846 init1: 300 opt: 540  Z-score: 587.8  bits: 117.6 E(85289): 5.3e-26
Smith-Waterman score: 858; 37.7% identity (66.5% similar) in 382 aa overlap (2-382:42-392)

                                            10        20        30 
pF1KB4                              MSKPAGSTSRILDIPCKVCGDRSSGKHYGVY
                                     ..:.      :.. : ::::.::::::::.
NP_005 GGDTNGVDKAGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCGDKSSGKHYGVF
              20        30        40        50        60        70 

              40        50        60        70        80        90 
pF1KB4 ACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCRACRLKKCLEVNMNKDAVQHE
       .:.::..::::::::: .:.:.:. .  : .:. :::::. ::::::..:.: :.:::. 
NP_005 TCEGCKSFFKRSIRRNLSYTCRSNRD--CQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRG
              80        90         100       110       120         

             100       110       120       130       140       150 
pF1KB4 RGPRTSTIRKQVALYFRGHKEENGAAAHFPSAALPAPAFFTAVTQLEPHGLELAAVSTTP
       : :               :.  ...::   :.. :  . ..::..    : .:   . . 
NP_005 RIP---------------HSLPGAVAA---SSGSPPGSALAAVAS----GGDLFPGQPVS
     130                      140          150           160       

             160       170        180       190       200       210
pF1KB4 ERQTLVSLAQPTPKYPHEVN-GTPMYLYEVATESVCESAARLLFMSIKWAKSVPAFSTLS
       :  . .  :.: :    . . :       .. ..::: :::::: ...::. .: :  : 
NP_005 ELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELP
       170       180       190       200       210       220       

              220       230       240       250       260       270
pF1KB4 LQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLAVSGMNGDNTDSQKLNKIISEIQALQE
       . ::. ::. .: :::::. :: :.:. .  :::..:...    ...   ......:.::
NP_005 VADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQE
       230       240       250       260       270       280       

              280       290       300       310       320       330
pF1KB4 VVARFRQLRLDATEFACLKCIVTFKAVPTHSGSELRSFRNAAAIAALQDEAQLTLNSYIH
        : .. .:..:..:..::: :. :  .:   :     . . : . .::..::..:. :..
NP_005 QVDKLGRLQVDSAEYGCLKAIALF--TPDACG-----LSDPAHVESLQEKAQVALTEYVR
       290       300       310              320       330       340

              340       350       360       370       380          
pF1KB4 TRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFKKTIGNVPITRLLSDMYKSSDI     
       ..::.:: :::.::: :::::..  : : ..:: . .:..::  :. ::  :        
NP_005 AQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPY
              350       360       370       380       390       400

NP_005 GSGQ
           

>>NP_001138629 (OMIM: 107773,615779) COUP transcription   (261 aa)
 initn: 553 init1: 312 opt: 532  Z-score: 582.0  bits: 115.9 E(85289): 1.1e-25
Smith-Waterman score: 532; 36.4% identity (71.5% similar) in 228 aa overlap (157-382:29-249)

        130       140       150       160       170         180    
pF1KB4 APAFFTAVTQLEPHGLELAAVSTTPERQTLVSLAQPTPKYPHEVNGTPMYLYE--VATES
                                     .::   .  ::    :.  .  .  .. :.
NP_001   MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIEN
                 10        20        30        40        50        

          190       200       210       220       230       240    
pF1KB4 VCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTLLA
       .:: :::.:: ...::...: :  :.. ::. ::. .: :::::. :: ..:. .  :::
NP_001 ICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLA
       60        70        80        90       100       110        

          250       260       270       280       290       300    
pF1KB4 VSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSGSE
       ..:....  .....  ....:. .:: : ... :..:..:..::: :: :        :.
NP_001 AAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFT-------SD
      120       130       140       150       160              170 

          310       320       330       340       350       360    
pF1KB4 LRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVFFK
         .. ..: . .::...: .:. :....::.:: ::::::: ::.::..: :.::..:: 
NP_001 ACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFV
             180       190       200       210       220       230 

          370       380              
pF1KB4 KTIGNVPITRLLSDMYKSSDI         
       . .:..::  :. ::  :            
NP_001 RLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
             240       250       260 




385 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 22:57:10 2016 done: Fri Nov  4 22:57:11 2016
 Total Scan time:  8.390 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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