Result of FASTA (omim) for pF1KB3641
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3641, 314 aa
  1>>>pF1KB3641 314 - 314 aa - 314 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.5826+/-0.000401; mu= 0.0380+/- 0.025
 mean_var=173.8363+/-34.362, 0's: 0 Z-trim(117.2): 55  B-trim: 48 in 1/52
 Lambda= 0.097276
 statistics sampled from 28915 (28970) to 28915 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.34), width:  16
 Scan time:  5.590

The best scores are:                                      opt bits E(85289)
NP_001035147 (OMIM: 166490) osteopontin isoform OP ( 314) 2110 308.2 1.4e-83
NP_001238759 (OMIM: 166490) osteopontin isoform 5  ( 327) 1912 280.4 3.4e-75
XP_016864053 (OMIM: 166490) PREDICTED: osteopontin ( 327) 1912 280.4 3.4e-75
NP_001035149 (OMIM: 166490) osteopontin isoform OP ( 287) 1718 253.1 4.9e-67
NP_000573 (OMIM: 166490) osteopontin isoform OPN-b ( 300) 1639 242.1 1.1e-63
NP_001238758 (OMIM: 166490) osteopontin isoform 4  ( 273) 1631 240.9 2.2e-63


>>NP_001035147 (OMIM: 166490) osteopontin isoform OPN-a   (314 aa)
 initn: 2110 init1: 2110 opt: 2110  Z-score: 1621.3  bits: 308.2 E(85289): 1.4e-83
Smith-Waterman score: 2110; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:1-314)

               10        20        30        40        50        60
pF1KB3 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
              250       260       270       280       290       300

              310    
pF1KB3 RISHELDSASSEVN
       ::::::::::::::
NP_001 RISHELDSASSEVN
              310    

>>NP_001238759 (OMIM: 166490) osteopontin isoform 5 [Hom  (327 aa)
 initn: 1910 init1: 1910 opt: 1912  Z-score: 1470.9  bits: 280.4 E(85289): 3.4e-75
Smith-Waterman score: 1912; 97.3% identity (98.0% similar) in 294 aa overlap (21-314:34-327)

                         10        20        30        40        50
pF1KB3           MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQ
                                     : :   .  :.:::::::::::::::::::
NP_001 VPRSLDKKAHRVQFQLNRIKAKIELPWGSLQLDCLMKTLKELYNKYPDAVATWLNPDPSQ
            10        20        30        40        50        60   

               60        70        80        90       100       110
pF1KB3 KQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
            70        80        90       100       110       120   

              120       130       140       150       160       170
pF1KB3 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
           130       140       150       160       170       180   

              180       190       200       210       220       230
pF1KB3 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
           190       200       210       220       230       240   

              240       250       260       270       280       290
pF1KB3 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
           250       260       270       280       290       300   

              300       310    
pF1KB3 SKEEDKHLKFRISHELDSASSEVN
       ::::::::::::::::::::::::
NP_001 SKEEDKHLKFRISHELDSASSEVN
           310       320       

>>XP_016864053 (OMIM: 166490) PREDICTED: osteopontin iso  (327 aa)
 initn: 1910 init1: 1910 opt: 1912  Z-score: 1470.9  bits: 280.4 E(85289): 3.4e-75
Smith-Waterman score: 1912; 97.3% identity (98.0% similar) in 294 aa overlap (21-314:34-327)

                         10        20        30        40        50
pF1KB3           MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQ
                                     : :   .  :.:::::::::::::::::::
XP_016 VPRSLDKKAHRVQFQLNRIKAKIELPWGSLQLDCLMKTLKELYNKYPDAVATWLNPDPSQ
            10        20        30        40        50        60   

               60        70        80        90       100       110
pF1KB3 KQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDD
            70        80        90       100       110       120   

              120       130       140       150       160       170
pF1KB3 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSK
           130       140       150       160       170       180   

              180       190       200       210       220       230
pF1KB3 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQL
           190       200       210       220       230       240   

              240       250       260       270       280       290
pF1KB3 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPK
           250       260       270       280       290       300   

              300       310    
pF1KB3 SKEEDKHLKFRISHELDSASSEVN
       ::::::::::::::::::::::::
XP_016 SKEEDKHLKFRISHELDSASSEVN
           310       320       

>>NP_001035149 (OMIM: 166490) osteopontin isoform OPN-c   (287 aa)
 initn: 1718 init1: 1718 opt: 1718  Z-score: 1324.6  bits: 253.1 E(85289): 4.9e-67
Smith-Waterman score: 1855; 91.4% identity (91.4% similar) in 314 aa overlap (1-314:1-287)

               10        20        30        40        50        60
pF1KB3 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
       :::::::::::::::::::::::::::::::                           ::
NP_001 MRIAVICFCLLGITCAIPVKQADSGSSEEKQ---------------------------NA
               10        20        30                              

               70        80        90       100       110       120
pF1KB3 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
            40        50        60        70        80        90   

              130       140       150       160       170       180
pF1KB3 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
           100       110       120       130       140       150   

              190       200       210       220       230       240
pF1KB3 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
           160       170       180       190       200       210   

              250       260       270       280       290       300
pF1KB3 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
           220       230       240       250       260       270   

              310    
pF1KB3 RISHELDSASSEVN
       ::::::::::::::
NP_001 RISHELDSASSEVN
           280       

>>NP_000573 (OMIM: 166490) osteopontin isoform OPN-b pre  (300 aa)
 initn: 1627 init1: 1627 opt: 1639  Z-score: 1264.4  bits: 242.1 E(85289): 1.1e-63
Smith-Waterman score: 1986; 95.5% identity (95.5% similar) in 314 aa overlap (1-314:1-300)

               10        20        30        40        50        60
pF1KB3 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
NP_000 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQ--
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KB3 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
                   ::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ------------TLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
                   60        70        80        90       100      

              130       140       150       160       170       180
pF1KB3 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
        110       120       130       140       150       160      

              190       200       210       220       230       240
pF1KB3 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
        170       180       190       200       210       220      

              250       260       270       280       290       300
pF1KB3 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
        230       240       250       260       270       280      

              310    
pF1KB3 RISHELDSASSEVN
       ::::::::::::::
NP_000 RISHELDSASSEVN
        290       300

>>NP_001238758 (OMIM: 166490) osteopontin isoform 4 prec  (273 aa)
 initn: 1630 init1: 1630 opt: 1631  Z-score: 1258.9  bits: 240.9 E(85289): 2.2e-63
Smith-Waterman score: 1741; 86.9% identity (86.9% similar) in 314 aa overlap (1-314:1-273)

               10        20        30        40        50        60
pF1KB3 MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNA
       :::::::::::::::::::::::::::::::                             
NP_001 MRIAVICFCLLGITCAIPVKQADSGSSEEKQ-----------------------------
               10        20        30                              

               70        80        90       100       110       120
pF1KB3 VSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
                   ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------TLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQS
                          40        50        60        70         

              130       140       150       160       170       180
pF1KB3 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQ
      80        90       100       110       120       130         

              190       200       210       220       230       240
pF1KB3 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSH
     140       150       160       170       180       190         

              250       260       270       280       290       300
pF1KB3 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKF
     200       210       220       230       240       250         

              310    
pF1KB3 RISHELDSASSEVN
       ::::::::::::::
NP_001 RISHELDSASSEVN
     260       270   




314 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 00:58:19 2016 done: Sat Nov  5 00:58:19 2016
 Total Scan time:  5.590 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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