Result of FASTA (omim) for pF1KB7575
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7575, 216 aa
  1>>>pF1KB7575 216 - 216 aa - 216 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1020+/-0.000356; mu= 10.9778+/- 0.022
 mean_var=98.6142+/-20.101, 0's: 0 Z-trim(115.6): 112  B-trim: 420 in 2/51
 Lambda= 0.129153
 statistics sampled from 26116 (26239) to 26116 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.308), width:  16
 Scan time:  6.620

The best scores are:                                      opt bits E(85289)
NP_001193668 (OMIM: 605494) centromere protein R i ( 216) 1384 267.8 9.9e-72
NP_055103 (OMIM: 605494) centromere protein R isof ( 177) 1097 214.2 1.1e-55
XP_016856344 (OMIM: 605494) PREDICTED: centromere  ( 211) 1036 202.9 3.2e-52
XP_006710578 (OMIM: 605494) PREDICTED: centromere  ( 295) 1004 197.1 2.6e-50
XP_016856343 (OMIM: 605494) PREDICTED: centromere  ( 223) 1002 196.6 2.7e-50
XP_006710577 (OMIM: 605494) PREDICTED: centromere  ( 303)  997 195.8 6.6e-50
XP_016856342 (OMIM: 605494) PREDICTED: centromere  ( 308)  997 195.8 6.7e-50
XP_016856346 (OMIM: 605494) PREDICTED: centromere  ( 185)  377 80.1 2.7e-15
XP_016856345 (OMIM: 605494) PREDICTED: centromere  ( 189)  375 79.7 3.5e-15
XP_016856721 (OMIM: 616773) PREDICTED: mitoguardin ( 553)  194 46.3 0.00012
XP_016856720 (OMIM: 616773) PREDICTED: mitoguardin ( 585)  194 46.3 0.00012
XP_016865721 (OMIM: 613973) PREDICTED: cyclic GMP- ( 497)  191 45.7 0.00016
XP_016873709 (OMIM: 602355) PREDICTED: TNF recepto ( 324)  188 45.0 0.00017
NP_001254494 (OMIM: 123812) cAMP-responsive elemen ( 131)  180 43.3 0.00023
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370)  185 44.5 0.00027
NP_001158312 (OMIM: 613311,615595) LYR motif-conta ( 130)  178 42.9 0.00029
XP_016880852 (OMIM: 614942) PREDICTED: CDP-diacylg ( 549)  184 44.5 0.00042
XP_011534200 (OMIM: 605196) PREDICTED: ubiquinone  ( 329)  179 43.4 0.00053
XP_016884212 (OMIM: 604589) PREDICTED: bromodomain ( 643)  183 44.3 0.00054
XP_006715563 (OMIM: 605196) PREDICTED: ubiquinone  ( 410)  179 43.4 0.00064
NP_001333021 (OMIM: 142680,191190,614810) tumor ne ( 302)  174 42.4 0.00095
NP_001275965 (OMIM: 616990) clusterin-like protein ( 518)  174 42.6  0.0015
XP_016882892 (OMIM: 608349) PREDICTED: hematopoiet ( 218)  168 41.2  0.0016
XP_016882891 (OMIM: 608349) PREDICTED: hematopoiet ( 225)  167 41.0  0.0019
NP_001243358 (OMIM: 605904) PDZ and LIM domain pro ( 136)  160 39.6  0.0031
NP_001264049 (OMIM: 616841) zinc finger protein 46 ( 127)  159 39.3  0.0033
XP_016870596 (OMIM: 602874) PREDICTED: ceramide gl ( 239)  162 40.1  0.0037
NP_001305856 (OMIM: 180480) ribulose-phosphate 3-e ( 225)  161 39.9   0.004
XP_016856700 (OMIM: 147522) PREDICTED: inositol-tr ( 730)  167 41.4  0.0047
XP_016875691 (OMIM: 615335) PREDICTED: ceramide sy ( 334)  162 40.2  0.0049
XP_006715517 (OMIM: 606457) PREDICTED: inhibitor o (1379)  170 42.1  0.0053
XP_006715516 (OMIM: 606457) PREDICTED: inhibitor o (1394)  170 42.1  0.0053
NP_001317999 (OMIM: 615335) ceramide synthase 5 is ( 392)  162 40.3  0.0055
NP_001186384 (OMIM: 601540) bromodomain-containing ( 836)  165 41.0  0.0068
NP_001287990 (OMIM: 605846) B-cell CLL/lymphoma 7  ( 213)  154 38.6  0.0096


>>NP_001193668 (OMIM: 605494) centromere protein R isofo  (216 aa)
 initn: 1384 init1: 1384 opt: 1384  Z-score: 1408.8  bits: 267.8 E(85289): 9.9e-72
Smith-Waterman score: 1384; 99.5% identity (99.5% similar) in 216 aa overlap (1-216:1-216)

               10        20        30        40        50        60
pF1KB7 MPFAPVAQAGVQWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPS
       ::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPFAPVAQARVQWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 KITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 DNDEFMMLLSKVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNDEFMMLLSKVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKE
              130       140       150       160       170       180

              190       200       210      
pF1KB7 LMTKVNKQKLFEKSTGLPHKASRHLDSYEFLKAILN
       ::::::::::::::::::::::::::::::::::::
NP_001 LMTKVNKQKLFEKSTGLPHKASRHLDSYEFLKAILN
              190       200       210      

>>NP_055103 (OMIM: 605494) centromere protein R isoform   (177 aa)
 initn: 1097 init1: 1097 opt: 1097  Z-score: 1121.0  bits: 214.2 E(85289): 1.1e-55
Smith-Waterman score: 1097; 100.0% identity (100.0% similar) in 175 aa overlap (42-216:3-177)

              20        30        40        50        60        70 
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
                                     ::::::::::::::::::::::::::::::
NP_055                             MPVKRSLKLDGLLEENSFDPSKITRKKSVITY
                                           10        20        30  

              80        90       100       110       120       130 
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
             40        50        60        70        80        90  

             140       150       160       170       180       190 
pF1KB7 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
            100       110       120       130       140       150  

             200       210      
pF1KB7 EKSTGLPHKASRHLDSYEFLKAILN
       :::::::::::::::::::::::::
NP_055 EKSTGLPHKASRHLDSYEFLKAILN
            160       170       

>>XP_016856344 (OMIM: 605494) PREDICTED: centromere prot  (211 aa)
 initn: 1039 init1: 1014 opt: 1036  Z-score: 1058.5  bits: 202.9 E(85289): 3.2e-52
Smith-Waterman score: 1036; 86.3% identity (90.4% similar) in 197 aa overlap (28-216:16-211)

               10        20        30                40        50  
pF1KB7 MPFAPVAQAGVQWHDFRSLQHLLPAFKRFSCLSL--------GSSWDYSVKRSLKLDGLL
                                  :::::..        :: :   ..:.  .    
XP_016             MFPPGRGGLDATSSARFSCLGVSFGGFSVFGSCWVRFIQRQWCFPES-
                           10        20        30        40        

             60        70        80        90       100       110  
pF1KB7 EENSFDPSKITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLT
       .. :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNASFDPSKITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLT
        50        60        70        80        90       100       

            120       130       140       150       160       170  
pF1KB7 ESKESTTKDNDEFMMLLSKVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKESTTKDNDEFMMLLSKVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLK
       110       120       130       140       150       160       

            180       190       200       210      
pF1KB7 REMQKTKELMTKVNKQKLFEKSTGLPHKASRHLDSYEFLKAILN
       ::::::::::::::::::::::::::::::::::::::::::::
XP_016 REMQKTKELMTKVNKQKLFEKSTGLPHKASRHLDSYEFLKAILN
       170       180       190       200       210 

>>XP_006710578 (OMIM: 605494) PREDICTED: centromere prot  (295 aa)
 initn: 997 init1: 997 opt: 1004  Z-score: 1024.2  bits: 197.1 E(85289): 2.6e-50
Smith-Waterman score: 1004; 95.3% identity (97.0% similar) in 169 aa overlap (42-210:125-293)

              20        30        40        50        60        70 
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
                                     ::::::::::::::::::::::::::::::
XP_006 AFPLADFLFSEVAGFVLFSGSGAFPNLRMPVKRSLKLDGLLEENSFDPSKITRKKSVITY
          100       110       120       130       140       150    

              80        90       100       110       120       130 
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
          160       170       180       190       200       210    

             140       150       160       170       180       190 
pF1KB7 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
          220       230       240       250       260       270    

             200       210      
pF1KB7 EKSTGLPHKASRHLDSYEFLKAILN
       ::::::::: .  : . .:      
XP_006 EKSTGLPHKDTSILKALRFEV    
          280       290         

>>XP_016856343 (OMIM: 605494) PREDICTED: centromere prot  (223 aa)
 initn: 1002 init1: 1002 opt: 1002  Z-score: 1023.9  bits: 196.6 E(85289): 2.7e-50
Smith-Waterman score: 1002; 100.0% identity (100.0% similar) in 160 aa overlap (41-200:39-198)

               20        30        40        50        60        70
pF1KB7 VQWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVIT
                                     ::::::::::::::::::::::::::::::
XP_016 IFCFRKLLGSFYSAAVVLSRISECRRYLLPSVKRSLKLDGLLEENSFDPSKITRKKSVIT
       10        20        30        40        50        60        

               80        90       100       110       120       130
pF1KB7 YSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLS
       70        80        90       100       110       120        

              140       150       160       170       180       190
pF1KB7 KVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKL
      130       140       150       160       170       180        

              200       210               
pF1KB7 FEKSTGLPHKASRHLDSYEFLKAILN         
       ::::::::::                         
XP_016 FEKSTGLPHKGIKADLPITRFSQRTEFLHRGDCYH
      190       200       210       220   

>>XP_006710577 (OMIM: 605494) PREDICTED: centromere prot  (303 aa)
 initn: 997 init1: 997 opt: 997  Z-score: 1017.0  bits: 195.8 E(85289): 6.6e-50
Smith-Waterman score: 997; 100.0% identity (100.0% similar) in 159 aa overlap (42-200:125-283)

              20        30        40        50        60        70 
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
                                     ::::::::::::::::::::::::::::::
XP_006 AFPLADFLFSEVAGFVLFSGSGAFPNLRMPVKRSLKLDGLLEENSFDPSKITRKKSVITY
          100       110       120       130       140       150    

              80        90       100       110       120       130 
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
          160       170       180       190       200       210    

             140       150       160       170       180       190 
pF1KB7 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
          220       230       240       250       260       270    

             200       210          
pF1KB7 EKSTGLPHKASRHLDSYEFLKAILN    
       :::::::::                    
XP_006 EKSTGLPHKGIKKKCTHHEHQLLHLPDHI
          280       290       300   

>>XP_016856342 (OMIM: 605494) PREDICTED: centromere prot  (308 aa)
 initn: 997 init1: 997 opt: 997  Z-score: 1016.9  bits: 195.8 E(85289): 6.7e-50
Smith-Waterman score: 997; 100.0% identity (100.0% similar) in 159 aa overlap (42-200:125-283)

              20        30        40        50        60        70 
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
                                     ::::::::::::::::::::::::::::::
XP_016 AFPLADFLFSEVAGFVLFSGSGAFPNLRMPVKRSLKLDGLLEENSFDPSKITRKKSVITY
          100       110       120       130       140       150    

              80        90       100       110       120       130 
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
          160       170       180       190       200       210    

             140       150       160       170       180       190 
pF1KB7 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLF
          220       230       240       250       260       270    

             200       210               
pF1KB7 EKSTGLPHKASRHLDSYEFLKAILN         
       :::::::::                         
XP_016 EKSTGLPHKGIKADLPITRFSQRTEFLHRGDCYH
          280       290       300        

>>XP_016856346 (OMIM: 605494) PREDICTED: centromere prot  (185 aa)
 initn: 377 init1: 377 opt: 377  Z-score: 395.7  bits: 80.1 E(85289): 2.7e-15
Smith-Waterman score: 377; 98.3% identity (100.0% similar) in 60 aa overlap (42-101:125-184)

              20        30        40        50        60        70 
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
                                     ::::::::::::::::::::::::::::::
XP_016 AFPLADFLFSEVAGFVLFSGSGAFPNLRMPVKRSLKLDGLLEENSFDPSKITRKKSVITY
          100       110       120       130       140       150    

              80        90       100       110       120       130 
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
       :::::::::::::::::::::::::::::.                              
XP_016 SPTTGTCQMSLFASPTSSEEQKHRNGLSNDS                             
          160       170       180                                  

>>XP_016856345 (OMIM: 605494) PREDICTED: centromere prot  (189 aa)
 initn: 375 init1: 375 opt: 375  Z-score: 393.6  bits: 79.7 E(85289): 3.5e-15
Smith-Waterman score: 375; 100.0% identity (100.0% similar) in 59 aa overlap (42-100:125-183)

              20        30        40        50        60        70 
pF1KB7 QWHDFRSLQHLLPAFKRFSCLSLGSSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITY
                                     ::::::::::::::::::::::::::::::
XP_016 AFPLADFLFSEVAGFVLFSGSGAFPNLRMPVKRSLKLDGLLEENSFDPSKITRKKSVITY
          100       110       120       130       140       150    

              80        90       100       110       120       130 
pF1KB7 SPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSK
       :::::::::::::::::::::::::::::                               
XP_016 SPTTGTCQMSLFASPTSSEEQKHRNGLSNGLCWKP                         
          160       170       180                                  

>>XP_016856721 (OMIM: 616773) PREDICTED: mitoguardin-1 i  (553 aa)
 initn: 194 init1: 194 opt: 194  Z-score: 204.7  bits: 46.3 E(85289): 0.00012
Smith-Waterman score: 194; 80.0% identity (85.7% similar) in 35 aa overlap (6-40:495-529)

                                        10        20        30     
pF1KB7                          MPFAPVAQAGVQWHDFRSLQHLLPAFKRFSCLSLG
                                     ::::::::::. ::: : : :::: ::::.
XP_016 NSSFKETAVASSCWSVLKQKRQQMKTESHSVAQAGVQWHDLSSLQPLPPRFKRFFCLSLS
          470       480       490       500       510       520    

          40        50        60        70        80        90     
pF1KB7 SSWDYSVKRSLKLDGLLEENSFDPSKITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHR
       :::::                                                       
XP_016 SSWDYRRLPPCPANLYIFGKDGVSSCWPG                               
          530       540       550                                  




216 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 01:35:07 2016 done: Sat Nov  5 01:35:08 2016
 Total Scan time:  6.620 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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