Result of FASTA (omim) for pF1KE1007
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1007, 196 aa
  1>>>pF1KE1007 196 - 196 aa - 196 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0498+/-0.000397; mu= 11.4523+/- 0.025
 mean_var=102.6219+/-19.758, 0's: 0 Z-trim(113.2): 28  B-trim: 165 in 1/53
 Lambda= 0.126606
 statistics sampled from 22431 (22458) to 22431 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.263), width:  16
 Scan time:  5.530

The best scores are:                                      opt bits E(85289)
NP_002759 (OMIM: 164010,614961) charged multivesic ( 196) 1196 228.5 5.3e-60
NP_065145 (OMIM: 606486) charged multivesicular bo ( 199)  682 134.6 9.8e-32
NP_055268 (OMIM: 610893) charged multivesicular bo ( 222)  258 57.2 2.2e-08
NP_940818 (OMIM: 610893) charged multivesicular bo ( 222)  258 57.2 2.2e-08
XP_005258804 (OMIM: 610893) PREDICTED: charged mul ( 265)  243 54.5 1.7e-07
XP_005258803 (OMIM: 610893) PREDICTED: charged mul ( 265)  243 54.5 1.7e-07
NP_054762 (OMIM: 600795,609512,614696) charged mul ( 213)  179 42.8 0.00047
XP_011531878 (OMIM: 600795,609512,614696) PREDICTE ( 229)  179 42.8  0.0005
NP_001231573 (OMIM: 600795,609512,614696) charged  ( 172)  163 39.8   0.003


>>NP_002759 (OMIM: 164010,614961) charged multivesicular  (196 aa)
 initn: 1196 init1: 1196 opt: 1196  Z-score: 1198.2  bits: 228.5 E(85289): 5.3e-60
Smith-Waterman score: 1196; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:1-196)

               10        20        30        40        50        60
pF1KE1 MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECARVYAENAIRKKNEGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECARVYAENAIRKKNEGV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 NWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 NLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSV
              130       140       150       160       170       180

              190      
pF1KE1 RSQEDQLSRRLAALRN
       ::::::::::::::::
NP_002 RSQEDQLSRRLAALRN
              190      

>>NP_065145 (OMIM: 606486) charged multivesicular body p  (199 aa)
 initn: 723 init1: 609 opt: 682  Z-score: 690.7  bits: 134.6 E(85289): 9.8e-32
Smith-Waterman score: 682; 55.8% identity (85.3% similar) in 197 aa overlap (1-196:4-197)

                  10        20        30        40        50       
pF1KE1    MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECARVYAENAIRKKN
          :.  ::.:::.::.: . ::: .:. :::.::.:::. . :.: ::..::::::.::
NP_065 MSNMEKHLFNLKFAAKELSRSAKKCDKEEKAEKAKIKKAIQKGNMEVARIHAENAIRQKN
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KE1 EGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQ
       ..::.:::..::::::..:::::::  :::.:: :.:..: .:.::.:.:.:..::.::.
NP_065 QAVNFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLKTMNLEKISALMDKFEH
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KE1 QVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGAS-AVG
       : ..:::.:. :::.:::.:::::::.::: :....:.: ::   :   .::.: . .::
NP_065 QFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGL---DLNMELPQGQTGSVG
              130       140       150       160          170       

        180       190        
pF1KE1 ESSVRSQEDQLSRRLAALRN  
        : . ...:.::.::: ::.  
NP_065 TSVASAEQDELSQRLARLRDQV
       180       190         

>>NP_055268 (OMIM: 610893) charged multivesicular body p  (222 aa)
 initn: 215 init1: 199 opt: 258  Z-score: 271.5  bits: 57.2 E(85289): 2.2e-08
Smith-Waterman score: 260; 27.1% identity (62.8% similar) in 199 aa overlap (8-195:22-220)

                             10        20        30        40      
pF1KE1               MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECAR
                            :. . ..:..  .: : . :   : .::   : ... .:
NP_055 MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR
               10        20        30        40        50        60

         50        60        70        80        90       100      
pF1KE1 VYAENAIRKKNEGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQ
       ..:.. .: .    ... : . ..::. :.::  . ..... :  ::::.      . : 
NP_055 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP
               70        80        90       100       110       120

        110       120       130       140       150       160      
pF1KE1 KVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLS
       .....: .::.:.. .:..  .:.:....:      .:. :... :. .: :: . :.::
NP_055 QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS
              130       140       150       160       170       180

        170               180          190       
pF1KE1 QLPE-GAS---AVG----ESSVRSQED---QLSRRLAALRN 
       .::  :.:   :.:    :... .  :   .: .::  ::  
NP_055 NLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD
              190       200       210       220  

>>NP_940818 (OMIM: 610893) charged multivesicular body p  (222 aa)
 initn: 215 init1: 199 opt: 258  Z-score: 271.5  bits: 57.2 E(85289): 2.2e-08
Smith-Waterman score: 260; 27.1% identity (62.8% similar) in 199 aa overlap (8-195:22-220)

                             10        20        30        40      
pF1KE1               MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECAR
                            :. . ..:..  .: : . :   : .::   : ... .:
NP_940 MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR
               10        20        30        40        50        60

         50        60        70        80        90       100      
pF1KE1 VYAENAIRKKNEGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQ
       ..:.. .: .    ... : . ..::. :.::  . ..... :  ::::.      . : 
NP_940 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP
               70        80        90       100       110       120

        110       120       130       140       150       160      
pF1KE1 KVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLS
       .....: .::.:.. .:..  .:.:....:      .:. :... :. .: :: . :.::
NP_940 QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS
              130       140       150       160       170       180

        170               180          190       
pF1KE1 QLPE-GAS---AVG----ESSVRSQED---QLSRRLAALRN 
       .::  :.:   :.:    :... .  :   .: .::  ::  
NP_940 NLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD
              190       200       210       220  

>>XP_005258804 (OMIM: 610893) PREDICTED: charged multive  (265 aa)
 initn: 200 init1: 184 opt: 243  Z-score: 255.7  bits: 54.5 E(85289): 1.7e-07
Smith-Waterman score: 243; 25.8% identity (64.8% similar) in 159 aa overlap (8-166:22-180)

                             10        20        30        40      
pF1KE1               MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECAR
                            :. . ..:..  .: : . :   : .::   : ... .:
XP_005 MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR
               10        20        30        40        50        60

         50        60        70        80        90       100      
pF1KE1 VYAENAIRKKNEGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQ
       ..:.. .: .    ... : . ..::. :.::  . ..... :  ::::.      . : 
XP_005 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP
               70        80        90       100       110       120

        110       120       130       140       150       160      
pF1KE1 KVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLS
       .....: .::.:.. .:..  .:.:....:      .:. :... :. .: :: . :.::
XP_005 QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS
              130       140       150       160       170       180

        170       180       190                                    
pF1KE1 QLPEGASAVGESSVRSQEDQLSRRLAALRN                              
                                                                   
XP_005 SECSKSWTPFPTQGPATAPSPPFPCITPLRCLTPPAQTPTFSADLPSTGGSLSVAAGGKK
              190       200       210       220       230       240

>>XP_005258803 (OMIM: 610893) PREDICTED: charged multive  (265 aa)
 initn: 200 init1: 184 opt: 243  Z-score: 255.7  bits: 54.5 E(85289): 1.7e-07
Smith-Waterman score: 243; 25.8% identity (64.8% similar) in 159 aa overlap (8-166:22-180)

                             10        20        30        40      
pF1KE1               MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECAR
                            :. . ..:..  .: : . :   : .::   : ... .:
XP_005 MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVR
               10        20        30        40        50        60

         50        60        70        80        90       100      
pF1KE1 VYAENAIRKKNEGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQ
       ..:.. .: .    ... : . ..::. :.::  . ..... :  ::::.      . : 
XP_005 IMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLP
               70        80        90       100       110       120

        110       120       130       140       150       160      
pF1KE1 KVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLS
       .....: .::.:.. .:..  .:.:....:      .:. :... :. .: :: . :.::
XP_005 QIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELS
              130       140       150       160       170       180

        170       180       190                                    
pF1KE1 QLPEGASAVGESSVRSQEDQLSRRLAALRN                              
                                                                   
XP_005 SECSKSWTPFPTQGPATAPSPPFPCITPLRCLTPPAQTPTFSADLPSTGGSLSVAAGGKK
              190       200       210       220       230       240

>>NP_054762 (OMIM: 600795,609512,614696) charged multive  (213 aa)
 initn: 152 init1:  57 opt: 179  Z-score: 193.8  bits: 42.8 E(85289): 0.00047
Smith-Waterman score: 191; 17.8% identity (63.9% similar) in 191 aa overlap (7-194:20-210)

                            10        20        30        40       
pF1KE1              MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECARV
                          .:. : . . .     ::. :  . ..::     : :  .:
NP_054 MASLFKKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKV
               10        20        30        40        50        60

        50        60        70        80        90       100       
pF1KE1 YAENAIRKKNEGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQK
        :.. .. ... .  . ..:.: ........  ..  ..  :. ..:... . . :: ::
NP_054 LAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQK
               70        80        90       100       110       120

       110       120       130       140       150       160       
pF1KE1 VSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQ
       . ..:. :... .....   ...:....    .  .:. .... :. .: :.:.  ....
NP_054 TLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAK
              130       140       150       160       170       180

       170       180          190       
pF1KE1 LPEGASAVGESSVRS---QEDQLSRRLAALRN 
        : .: ..  .:. .   ..... :.: ::   
NP_054 APSAARSLPSASTSKATISDEEIERQLKALGVD
              190       200       210   

>>XP_011531878 (OMIM: 600795,609512,614696) PREDICTED: c  (229 aa)
 initn: 128 init1:  57 opt: 179  Z-score: 193.3  bits: 42.8 E(85289): 0.0005
Smith-Waterman score: 191; 17.8% identity (63.9% similar) in 191 aa overlap (7-194:36-226)

                                       10        20        30      
pF1KE1                         MDDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKA
                                     .:. : . . .     ::. :  . ..:: 
XP_011 RNHHLPDSSDSSTSAYRVARITDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKM
          10        20        30        40        50        60     

         40        50        60        70        80        90      
pF1KE1 LLQKNVECARVYAENAIRKKNEGVNWLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKAL
           : :  .: :.. .. ... .  . ..:.: ........  ..  ..  :. ..:..
XP_011 AKIGNKEACKVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTM
          70        80        90       100       110       120     

        100       110       120       130       140       150      
pF1KE1 DKALSTMDLQKVSSVMDRFEQQVQNLDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEE
       . . . :: ::. ..:. :... .....   ...:....    .  .:. .... :. .:
XP_011 QAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDE
         130       140       150       160       170       180     

        160       170       180          190       
pF1KE1 NGLEVLDQLSQLPEGASAVGESSVRS---QEDQLSRRLAALRN 
        :.:.  .... : .: ..  .:. .   ..... :.: ::   
XP_011 IGIEISGKMAKAPSAARSLPSASTSKATISDEEIERQLKALGVD
         190       200       210       220         

>>NP_001231573 (OMIM: 600795,609512,614696) charged mult  (172 aa)
 initn: 141 init1:  57 opt: 163  Z-score: 179.3  bits: 39.8 E(85289): 0.003
Smith-Waterman score: 175; 17.5% identity (66.3% similar) in 166 aa overlap (32-194:4-169)

              10        20        30        40        50        60 
pF1KE1 DDTLFQLKFTAKQLEKLAKKAEKDSKAEQAKVKKALLQKNVECARVYAENAIRKKNEGVN
                                     ..::     : :  .: :.. .. ... . 
NP_001                            MELEIKKMAKIGNKEACKVLAKQLVHLRKQKTR
                                          10        20        30   

              70        80        90       100       110       120 
pF1KE1 WLRMASRVDAVASKVQTAVTMKGVTKNMAQVTKALDKALSTMDLQKVSSVMDRFEQQVQN
        . ..:.: ........  ..  ..  :. ..:... . . :: ::. ..:. :... ..
NP_001 TFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMK
            40        50        60        70        80        90   

             130       140       150       160       170       180 
pF1KE1 LDVHTSVMEDSMSSATTLTTPQEQVDSLIMQIAEENGLEVLDQLSQLPEGASAVGESSVR
       ...   ...:....    .  .:. .... :. .: :.:.  .... : .: ..  .:. 
NP_001 MEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAARSLPSASTS
           100       110       120       130       140       150   

                190       
pF1KE1 S---QEDQLSRRLAALRN 
       .   ..... :.: ::   
NP_001 KATISDEEIERQLKALGVD
           160       170  




196 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 13:22:52 2016 done: Sat Nov  5 13:22:53 2016
 Total Scan time:  5.530 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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