Result of FASTA (omim) for pF1KB7975
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7975, 427 aa
  1>>>pF1KB7975 427 - 427 aa - 427 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3957+/-0.000318; mu= 18.6169+/- 0.020
 mean_var=88.6617+/-17.904, 0's: 0 Z-trim(117.4): 12  B-trim: 60 in 1/53
 Lambda= 0.136209
 statistics sampled from 29381 (29393) to 29381 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.345), width:  16
 Scan time:  9.260

The best scores are:                                      opt bits E(85289)
NP_079491 (OMIM: 600462,608109) tRNA pseudouridine ( 427) 2931 585.7 7.4e-167
NP_001002019 (OMIM: 600462,608109) tRNA pseudourid ( 399) 2729 546.0 6.3e-155
NP_001002020 (OMIM: 600462,608109) tRNA pseudourid ( 399) 2729 546.0 6.3e-155
XP_011537070 (OMIM: 600462,608109) PREDICTED: tRNA ( 294) 1990 400.7 2.6e-111
XP_011537071 (OMIM: 600462,608109) PREDICTED: tRNA ( 216) 1039 213.7 3.7e-55
XP_005271745 (OMIM: 616283,617051) PREDICTED: tRNA ( 176)  165 41.9  0.0016
NP_112597 (OMIM: 616283,617051) tRNA pseudouridine ( 481)  165 42.2  0.0034


>>NP_079491 (OMIM: 600462,608109) tRNA pseudouridine syn  (427 aa)
 initn: 2931 init1: 2931 opt: 2931  Z-score: 3116.6  bits: 585.7 E(85289): 7.4e-167
Smith-Waterman score: 2931; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)

               10        20        30        40        50        60
pF1KB7 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
              370       380       390       400       410       420

              
pF1KB7 EGDGDTD
       :::::::
NP_079 EGDGDTD
              

>>NP_001002019 (OMIM: 600462,608109) tRNA pseudouridine   (399 aa)
 initn: 2729 init1: 2729 opt: 2729  Z-score: 2902.5  bits: 546.0 E(85289): 6.3e-155
Smith-Waterman score: 2729; 100.0% identity (100.0% similar) in 399 aa overlap (29-427:1-399)

               10        20        30        40        50        60
pF1KB7 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
                                   ::::::::::::::::::::::::::::::::
NP_001                             MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
                                           10        20        30  

               70        80        90       100       110       120
pF1KB7 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
             40        50        60        70        80        90  

              130       140       150       160       170       180
pF1KB7 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
            100       110       120       130       140       150  

              190       200       210       220       230       240
pF1KB7 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
            160       170       180       190       200       210  

              250       260       270       280       290       300
pF1KB7 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
            220       230       240       250       260       270  

              310       320       330       340       350       360
pF1KB7 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
            280       290       300       310       320       330  

              370       380       390       400       410       420
pF1KB7 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
            340       350       360       370       380       390  

              
pF1KB7 EGDGDTD
       :::::::
NP_001 EGDGDTD
              

>>NP_001002020 (OMIM: 600462,608109) tRNA pseudouridine   (399 aa)
 initn: 2729 init1: 2729 opt: 2729  Z-score: 2902.5  bits: 546.0 E(85289): 6.3e-155
Smith-Waterman score: 2729; 100.0% identity (100.0% similar) in 399 aa overlap (29-427:1-399)

               10        20        30        40        50        60
pF1KB7 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
                                   ::::::::::::::::::::::::::::::::
NP_001                             MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
                                           10        20        30  

               70        80        90       100       110       120
pF1KB7 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
             40        50        60        70        80        90  

              130       140       150       160       170       180
pF1KB7 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
            100       110       120       130       140       150  

              190       200       210       220       230       240
pF1KB7 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYK
            160       170       180       190       200       210  

              250       260       270       280       290       300
pF1KB7 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGL
            220       230       240       250       260       270  

              310       320       330       340       350       360
pF1KB7 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQ
            280       290       300       310       320       330  

              370       380       390       400       410       420
pF1KB7 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGS
            340       350       360       370       380       390  

              
pF1KB7 EGDGDTD
       :::::::
NP_001 EGDGDTD
              

>>XP_011537070 (OMIM: 600462,608109) PREDICTED: tRNA pse  (294 aa)
 initn: 1990 init1: 1990 opt: 1990  Z-score: 2119.4  bits: 400.7 E(85289): 2.6e-111
Smith-Waterman score: 1990; 100.0% identity (100.0% similar) in 294 aa overlap (134-427:1-294)

           110       120       130       140       150       160   
pF1KB7 VGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLI
                                     ::::::::::::::::::::::::::::::
XP_011                               MRKMSFQRCARTDKGVSAAGQVVSLKVWLI
                                             10        20        30

           170       180       190       200       210       220   
pF1KB7 DDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYR
               40        50        60        70        80        90

           230       240       250       260       270       280   
pF1KB7 LSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIR
              100       110       120       130       140       150

           290       300       310       320       330       340   
pF1KB7 VKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKY
              160       170       180       190       200       210

           350       360       370       380       390       400   
pF1KB7 NQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATA
              220       230       240       250       260       270

           410       420       
pF1KB7 LTAGGTGAKVPSPLEGSEGDGDTD
       ::::::::::::::::::::::::
XP_011 LTAGGTGAKVPSPLEGSEGDGDTD
              280       290    

>>XP_011537071 (OMIM: 600462,608109) PREDICTED: tRNA pse  (216 aa)
 initn: 1039 init1: 1039 opt: 1039  Z-score: 1111.2  bits: 213.7 E(85289): 3.7e-55
Smith-Waterman score: 1039; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)

               10        20        30        40        50        60
pF1KB7 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGLQLRALLGAFGRWTLRLGPRPSCSPRMAGNAEPPPAGAACPQDRRSCSGRAGGDRVWE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSAL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 VRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRI
       :::::::::::::::::::::::::::                                 
XP_011 VRSGCIPENHGEDMRKMSFQRCARTDKSQDLILLPRLECSGMIMAHCSLKLLGSSNPPAS
              130       140       150       160       170       180

>>XP_005271745 (OMIM: 616283,617051) PREDICTED: tRNA pse  (176 aa)
 initn: 156 init1: 108 opt: 165  Z-score: 184.1  bits: 41.9 E(85289): 0.0016
Smith-Waterman score: 165; 39.5% identity (71.1% similar) in 76 aa overlap (83-158:62-130)

             60        70        80        90       100       110  
pF1KB7 AGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTI
                                     .:...: .:: : ::.:.  . ....  ::
XP_005 QAKNKEDSNIRENSAGAGKTKRAFDFSAHGRRHVALRIAYMGWGYQGFASQENTNN--TI
              40        50        60        70        80           

            120       130       140       150       160       170  
pF1KB7 EDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINS
       :. :  ::...  .     :. .  ...::.:::::::: :::.::              
XP_005 EEKLFEALTKTRLV-----ESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPRGRDSED
      90       100            110       120       130       140    

            180       190       200       210       220       230  
pF1KB7 HLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQV
                                                                   
XP_005 FNVKEEANAAAEEIRYTHILNRYGCRISSSLI                            
          150       160       170                                  

>>NP_112597 (OMIM: 616283,617051) tRNA pseudouridine(38/  (481 aa)
 initn: 253 init1: 108 opt: 165  Z-score: 178.4  bits: 42.2 E(85289): 0.0034
Smith-Waterman score: 270; 25.4% identity (53.8% similar) in 342 aa overlap (83-396:62-374)

             60        70        80        90       100       110  
pF1KB7 AGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTI
                                     .:...: .:: : ::.:.  . ....  ::
NP_112 QAKNKEDSNIRENSAGAGKTKRAFDFSAHGRRHVALRIAYMGWGYQGFASQENTNN--TI
              40        50        60        70        80           

            120       130       140       150       160            
pF1KB7 EDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLI-----D---
       :. :  ::...  .     :. .  ...::.:::::::: :::.:: .        :   
NP_112 EEKLFEALTKTRLV-----ESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPRGRDSED
      90       100            110       120       130       140    

           170                    180       190       200       210
pF1KB7 -DILEKIN--------SH-----LPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAF
        .. :. :        .:     ::  ::::.   :  .:...  :  ::: :..:   .
NP_112 FNVKEEANAAAEEIRYTHILNRVLPPDIRILAWAPVEPSFSARFSCLERTYRYFFPRADL
          150       160       170       180       190       200    

              220       230       240         250         260      
pF1KB7 AHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHN--FTSQKG--PQDPSACRYILEM
            :   . : .... .... ..    .:. ::.   ...:     :.:.  :.    
NP_112 DIVTMDYAAQKY-VGTHDFRNLCKM-DVANGVINFQRTILSAQVQLVGQSPGEGRW----
          210        220        230       240       250            

        270       280       290       300       310       320      
pF1KB7 YCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVP
         .:::     ..  ..: ::.:..::.: :....  : .:.    ....  . ::   :
NP_112 --QEPF-----QLCQFEVTGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIEKN--P
        260            270       280       290       300           

        330       340       350         360       370       380    
pF1KB7 KAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWA--QEEGKVAAFKEEHIYPTIIGTERDE
       . :  ....:   .  :. .: :      . :   ::  .    . .... .     .  
NP_112 QKPQYSMAVE-FPLVLYDCKFEN------VKWIYDQEAQEFNITHLQQLWANHAVKTHML
     310        320       330             340       350       360  

          390       400       410       420                        
pF1KB7 RSMAQWLSTLPIHNFSATALTAGGTGAKVPSPLEGSEGDGDTD                 
        :: : :.:.:.                                                
NP_112 YSMLQGLDTVPVPCGIGPKMDGMTEWGNVKPSVIKQTSAFVEGVKMRTYKPLMDRPKCQG
            370       380       390       400       410       420  




427 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 14:48:57 2016 done: Sat Nov  5 14:48:58 2016
 Total Scan time:  9.260 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com