Result of FASTA (omim) for pF1KB6681
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6681, 427 aa
  1>>>pF1KB6681 427 - 427 aa - 427 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.0335+/-0.000683; mu= -11.1031+/- 0.042
 mean_var=291.5401+/-59.799, 0's: 0 Z-trim(111.9): 55  B-trim: 466 in 1/52
 Lambda= 0.075115
 statistics sampled from 20589 (20622) to 20589 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.578), E-opt: 0.2 (0.242), width:  16
 Scan time:  7.450

The best scores are:                                      opt bits E(85289)
NP_005794 (OMIM: 606998) flotillin-1 isoform 1 [Ho ( 427) 2658 302.4 1.5e-81
XP_005248837 (OMIM: 606998) PREDICTED: flotillin-1 ( 427) 2658 302.4 1.5e-81
XP_016865646 (OMIM: 606998) PREDICTED: flotillin-1 ( 423) 2389 273.2 8.8e-73
XP_006715010 (OMIM: 606998) PREDICTED: flotillin-1 ( 374) 2191 251.7 2.3e-66
XP_016865647 (OMIM: 606998) PREDICTED: flotillin-1 ( 390) 2189 251.5 2.8e-66
NP_001305804 (OMIM: 606998) flotillin-1 isoform 2  ( 379) 1888 218.9 1.8e-56
NP_001317099 (OMIM: 131560) flotillin-2 isoform 2  ( 428) 1240 148.7 2.7e-35
NP_004466 (OMIM: 131560) flotillin-2 isoform 1 [Ho ( 428) 1240 148.7 2.7e-35
XP_016879885 (OMIM: 131560) PREDICTED: flotillin-2 ( 379) 1133 137.1 7.6e-32
XP_016879884 (OMIM: 131560) PREDICTED: flotillin-2 ( 379) 1131 136.9 8.8e-32
XP_016879883 (OMIM: 131560) PREDICTED: flotillin-2 ( 379) 1131 136.9 8.8e-32
XP_005258010 (OMIM: 131560) PREDICTED: flotillin-2 ( 351) 1054 128.5 2.7e-29


>>NP_005794 (OMIM: 606998) flotillin-1 isoform 1 [Homo s  (427 aa)
 initn: 2658 init1: 2658 opt: 2658  Z-score: 1585.1  bits: 302.4 E(85289): 1.5e-81
Smith-Waterman score: 2658; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)

               10        20        30        40        50        60
pF1KB6 MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 YKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 AEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 EKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 LPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVN
              370       380       390       400       410       420

              
pF1KB6 HKPLRTA
       :::::::
NP_005 HKPLRTA
              

>>XP_005248837 (OMIM: 606998) PREDICTED: flotillin-1 iso  (427 aa)
 initn: 2658 init1: 2658 opt: 2658  Z-score: 1585.1  bits: 302.4 E(85289): 1.5e-81
Smith-Waterman score: 2658; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)

               10        20        30        40        50        60
pF1KB6 MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 YKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 AEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 EKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 LPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVN
              370       380       390       400       410       420

              
pF1KB6 HKPLRTA
       :::::::
XP_005 HKPLRTA
              

>>XP_016865646 (OMIM: 606998) PREDICTED: flotillin-1 iso  (423 aa)
 initn: 2388 init1: 2388 opt: 2389  Z-score: 1427.7  bits: 273.2 E(85289): 8.8e-73
Smith-Waterman score: 2389; 99.0% identity (99.2% similar) in 395 aa overlap (33-427:29-423)

             10        20        30        40        50        60  
pF1KB6 FTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVP
                                     :  . :::::::::::::::::::::::::
XP_016   MEPGAAEKQGERGKLQPEPCFSLVAQMRPWWSPIQRISLNTLTLNVKSEKVYTRHGVP
                 10        20        30        40        50        

             70        80        90       100       110       120  
pF1KB6 ISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYK
       60        70        80        90       100       110        

            130       140       150       160       170       180  
pF1KB6 DRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAE
      120       130       140       150       160       170        

            190       200       210       220       230       240  
pF1KB6 AKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQV
      180       190       200       210       220       230        

            250       260       270       280       290       300  
pF1KB6 AKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEAEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEAEK
      240       250       260       270       280       290        

            310       320       330       340       350       360  
pF1KB6 SQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEKLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEKLP
      300       310       320       330       340       350        

            370       380       390       400       410       420  
pF1KB6 QVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVNHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVNHK
      360       370       380       390       400       410        

            
pF1KB6 PLRTA
       :::::
XP_016 PLRTA
      420   

>>XP_006715010 (OMIM: 606998) PREDICTED: flotillin-1 iso  (374 aa)
 initn: 2276 init1: 2191 opt: 2191  Z-score: 1312.5  bits: 251.7 E(85289): 2.3e-66
Smith-Waterman score: 2191; 99.7% identity (100.0% similar) in 358 aa overlap (70-427:17-374)

      40        50        60        70        80        90         
pF1KB6 RISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHI
                                     .:::::::::::::::::::::::::::::
XP_006               MFFTCGPNEAMVVSDPEVKIQGQNKEMLAAACQMFLGKTEAEIAHI
                             10        20        30        40      

     100       110       120       130       140       150         
pF1KB6 ALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQD
         50        60        70        80        90       100      

     160       170       180       190       200       210         
pF1KB6 YLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELK
        110       120       130       140       150       160      

     220       230       240       250       260       270         
pF1KB6 KAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKEL
        170       180       190       200       210       220      

     280       290       300       310       320       330         
pF1KB6 EARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMA
        230       240       250       260       270       280      

     340       350       360       370       380       390         
pF1KB6 KKAEAFQLYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKAEAFQLYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLD
        290       300       310       320       330       340      

     400       410       420       
pF1KB6 ILTRLPESVERLTGVSISQVNHKPLRTA
       ::::::::::::::::::::::::::::
XP_006 ILTRLPESVERLTGVSISQVNHKPLRTA
        350       360       370    

>>XP_016865647 (OMIM: 606998) PREDICTED: flotillin-1 iso  (390 aa)
 initn: 2189 init1: 2189 opt: 2189  Z-score: 1311.0  bits: 251.5 E(85289): 2.8e-66
Smith-Waterman score: 2189; 100.0% identity (100.0% similar) in 357 aa overlap (71-427:34-390)

               50        60        70        80        90       100
pF1KB6 ISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIA
                                     ::::::::::::::::::::::::::::::
XP_016 GAAEKQGERGKLQPEPCFSLVAQMRPWWSPVKIQGQNKEMLAAACQMFLGKTEAEIAHIA
            10        20        30        40        50        60   

              110       120       130       140       150       160
pF1KB6 LETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDY
            70        80        90       100       110       120   

              170       180       190       200       210       220
pF1KB6 LHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKK
           130       140       150       160       170       180   

              230       240       250       260       270       280
pF1KB6 AAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELE
           190       200       210       220       230       240   

              290       300       310       320       330       340
pF1KB6 ARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAK
           250       260       270       280       290       300   

              350       360       370       380       390       400
pF1KB6 KAEAFQLYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAEAFQLYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDI
           310       320       330       340       350       360   

              410       420       
pF1KB6 LTRLPESVERLTGVSISQVNHKPLRTA
       :::::::::::::::::::::::::::
XP_016 LTRLPESVERLTGVSISQVNHKPLRTA
           370       380       390

>>NP_001305804 (OMIM: 606998) flotillin-1 isoform 2 [Hom  (379 aa)
 initn: 1887 init1: 1887 opt: 1888  Z-score: 1134.9  bits: 218.9 E(85289): 1.8e-56
Smith-Waterman score: 2248; 88.8% identity (88.8% similar) in 427 aa overlap (1-427:1-379)

               10        20        30        40        50        60
pF1KB6 MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEI
       ::::::::::                                                ::
NP_001 VPISVTGIAQ------------------------------------------------EI
               70                                                  

              130       140       150       160       170       180
pF1KB6 YKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGE
             80        90       100       110       120       130  

              190       200       210       220       230       240
pF1KB6 AEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQL
            140       150       160       170       180       190  

              250       260       270       280       290       300
pF1KB6 QVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEA
            200       210       220       230       240       250  

              310       320       330       340       350       360
pF1KB6 EKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEK
            260       270       280       290       300       310  

              370       380       390       400       410       420
pF1KB6 LPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVN
            320       330       340       350       360       370  

              
pF1KB6 HKPLRTA
       :::::::
NP_001 HKPLRTA
              

>>NP_001317099 (OMIM: 131560) flotillin-2 isoform 2 [Hom  (428 aa)
 initn: 1406 init1: 987 opt: 1240  Z-score: 754.6  bits: 148.7 E(85289): 2.7e-35
Smith-Waterman score: 1240; 47.6% identity (80.6% similar) in 418 aa overlap (4-419:6-417)

                 10        20          30        40        50      
pF1KB6   MFFTCGPNEAMVVSGFCRSPPV--MVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVY
            : :::::.:::: : .     .: :: ...  ::.. ::.::...:.  . :.. 
NP_001 MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRLSLEVMTILCRCENIE
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB6 TRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMT
       : .:::. :::.:::::. . ::.::.::..::::.  .: ...:.::::: :.:.. .:
NP_001 TSEGVPLFVTGVAQVKIMTE-KELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLT
               70        80         90       100       110         

        120       130       140       150       160       170      
pF1KB6 VEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDA
       ::.::.::..:.. : .::. :.  ::: ..:.:.::..:  ::: ::::..:: ::.::
NP_001 VEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDA
     120       130       140       150       160       170         

        180       190       200       210       220       230      
pF1KB6 RIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADL
        :: :::.::::::::. :.: ........ ..: ..: .::.:.:.. ::: . :.:.:
NP_001 DIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQL
     180       190       200       210       220       230         

        240       250       260       270       280       290      
pF1KB6 AYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLER
       ::.:: :. .:.:........::.: .:.::. ::: : .::: : ::.::::: .....
NP_001 AYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQ
     240       250       260       270       280       290         

        300       310       320       330       340       350      
pF1KB6 LAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDM
       .::.:: . .. :.::: ..:  ::::: .: : ..::::.:  ::::.: : .::.. .
NP_001 IAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMAL
     300       310       320       330       340       350         

        360       370       380       390       400       410      
pF1KB6 LLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSI
       .:: :::.: .:..:::....: .: ::...    :::.::  .:..:: ::. ::::..
NP_001 VLEALPQIAAKIAAPLTKVDEI-VVLSGDNS----KVTSEVNRLLAELPASVHALTGVDL
     360       370       380            390       400       410    

        420          
pF1KB6 SQVNHKPLRTA   
       :..           
NP_001 SKIPLIKKATGVQV
          420        

>>NP_004466 (OMIM: 131560) flotillin-2 isoform 1 [Homo s  (428 aa)
 initn: 1406 init1: 987 opt: 1240  Z-score: 754.6  bits: 148.7 E(85289): 2.7e-35
Smith-Waterman score: 1240; 48.1% identity (80.4% similar) in 418 aa overlap (4-419:6-417)

                 10        20          30        40        50      
pF1KB6   MFFTCGPNEAMVVSGFCRSPPV--MVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVY
            : :::::.:::: : .     .: :: ...  ::.. :::::. .::. . : : 
NP_004 MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQRISLEIMTLQPRCEDVE
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB6 TRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMT
       : .:: ..:::.:::::. . ::.::.::..::::.  .: ...:.::::: :.:.. .:
NP_004 TAEGVALTVTGVAQVKIMTE-KELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLT
               70        80         90       100       110         

        120       130       140       150       160       170      
pF1KB6 VEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDA
       ::.::.::..:.. : .::. :.  ::: ..:.:.::..:  ::: ::::..:: ::.::
NP_004 VEQIYQDRDQFAKLVREVAAPDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDA
     120       130       140       150       160       170         

        180       190       200       210       220       230      
pF1KB6 RIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADL
        :: :::.::::::::. :.: ........ ..: ..: .::.:.:.. ::: . :.:.:
NP_004 DIGVAEAERDAGIREAECKKEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQL
     180       190       200       210       220       230         

        240       250       260       270       280       290      
pF1KB6 AYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLER
       ::.:: :. .:.:........::.: .:.::. ::: : .::: : ::.::::: .....
NP_004 AYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQ
     240       250       260       270       280       290         

        300       310       320       330       340       350      
pF1KB6 LAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDM
       .::.:: . .. :.::: ..:  ::::: .: : ..::::.:  ::::.: : .::.. .
NP_004 IAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMAL
     300       310       320       330       340       350         

        360       370       380       390       400       410      
pF1KB6 LLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSI
       .:: :::.: .:..:::....: .: ::...    :::.::  .:..:: ::. ::::..
NP_004 VLEALPQIAAKIAAPLTKVDEI-VVLSGDNS----KVTSEVNRLLAELPASVHALTGVDL
     360       370       380            390       400       410    

        420          
pF1KB6 SQVNHKPLRTA   
       :..           
NP_004 SKIPLIKKATGVQV
          420        

>>XP_016879885 (OMIM: 131560) PREDICTED: flotillin-2 iso  (379 aa)
 initn: 1279 init1: 987 opt: 1133  Z-score: 692.8  bits: 137.1 E(85289): 7.6e-32
Smith-Waterman score: 1133; 47.9% identity (81.8% similar) in 374 aa overlap (46-419:1-368)

          20        30        40        50        60        70     
pF1KB6 FCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQG
                                     .:.  . :.. : .:::. :::.:::::. 
XP_016                               MTILCRCENIETSEGVPLFVTGVAQVKIMT
                                             10        20        30

          80        90       100       110       120       130     
pF1KB6 QNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVA
       . ::.::.::..::::.  .: ...:.::::: :.:.. .:::.::.::..:.. : .::
XP_016 E-KELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVA
                40        50        60        70        80         

         140       150       160       170       180       190     
pF1KB6 SSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAK
       . :.  ::: ..:.:.::..:  ::: ::::..:: ::.:: :: :::.::::::::. :
XP_016 APDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECK
      90       100       110       120       130       140         

         200       210       220       230       240       250     
pF1KB6 QEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQ
       .: ........ ..: ..: .::.:.:.. ::: . :.:.:::.:: :. .:.:......
XP_016 KEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIE
     150       160       170       180       190       200         

         260       270       280       290       300       310     
pF1KB6 VQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAAS
       ..::.: .:.::. ::: : .::: : ::.::::: ......::.:: . .. :.::: .
XP_016 IEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEK
     210       220       230       240       250       260         

         320       330       340       350       360       370     
pF1KB6 VRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEKLPQVAEEISGPLTSA
       .:  ::::: .: : ..::::.:  ::::.: : .::.. ..:: :::.: .:..:::..
XP_016 IRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKIAAPLTKV
     270       280       290       300       310       320         

         380       390       400       410       420          
pF1KB6 NKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVNHKPLRTA   
       ..: .: ::...    :::.::  .:..:: ::. ::::..:..           
XP_016 DEI-VVLSGDNS----KVTSEVNRLLAELPASVHALTGVDLSKIPLIKKATGVQV
     330        340           350       360       370         

>>XP_016879884 (OMIM: 131560) PREDICTED: flotillin-2 iso  (379 aa)
 initn: 1293 init1: 987 opt: 1131  Z-score: 691.6  bits: 136.9 E(85289): 8.8e-32
Smith-Waterman score: 1131; 48.1% identity (81.8% similar) in 374 aa overlap (46-419:1-368)

          20        30        40        50        60        70     
pF1KB6 FCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQG
                                     .::. . : : : .:: ..:::.:::::. 
XP_016                               MTLQPRCEDVETAEGVALTVTGVAQVKIMT
                                             10        20        30

          80        90       100       110       120       130     
pF1KB6 QNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVA
       . ::.::.::..::::.  .: ...:.::::: :.:.. .:::.::.::..:.. : .::
XP_016 E-KELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVA
                40        50        60        70        80         

         140       150       160       170       180       190     
pF1KB6 SSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAK
       . :.  ::: ..:.:.::..:  ::: ::::..:: ::.:: :: :::.::::::::. :
XP_016 APDVGRMGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECK
      90       100       110       120       130       140         

         200       210       220       230       240       250     
pF1KB6 QEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQ
       .: ........ ..: ..: .::.:.:.. ::: . :.:.:::.:: :. .:.:......
XP_016 KEMLDVKFMADTKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIE
     150       160       170       180       190       200         

         260       270       280       290       300       310     
pF1KB6 VQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAAS
       ..::.: .:.::. ::: : .::: : ::.::::: ......::.:: . .. :.::: .
XP_016 IEVVQRKKQIAVEAQEILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEK
     210       220       230       240       250       260         

         320       330       340       350       360       370     
pF1KB6 VRMRGEAEAFAIGARARAEAEQMAKKAEAFQLYQEAAQLDMLLEKLPQVAEEISGPLTSA
       .:  ::::: .: : ..::::.:  ::::.: : .::.. ..:: :::.: .:..:::..
XP_016 IRKIGEAEAAVIEAMGKAEAERMKLKAEAYQKYGDAAKMALVLEALPQIAAKIAAPLTKV
     270       280       290       300       310       320         

         380       390       400       410       420          
pF1KB6 NKITLVSSGSGTMGAAKVTGEVLDILTRLPESVERLTGVSISQVNHKPLRTA   
       ..: .: ::...    :::.::  .:..:: ::. ::::..:..           
XP_016 DEI-VVLSGDNS----KVTSEVNRLLAELPASVHALTGVDLSKIPLIKKATGVQV
     330        340           350       360       370         




427 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:45:19 2016 done: Sat Nov  5 11:45:20 2016
 Total Scan time:  7.450 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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