Result of FASTA (omim) for pF1KB3606
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3606, 198 aa
  1>>>pF1KB3606 198 - 198 aa - 198 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.8070+/-0.000336; mu= 15.2871+/- 0.021
 mean_var=50.6689+/-10.094, 0's: 0 Z-trim(114.3): 25  B-trim: 342 in 1/49
 Lambda= 0.180179
 statistics sampled from 24101 (24126) to 24101 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.283), width:  16
 Scan time:  5.860

The best scores are:                                      opt bits E(85289)
NP_005800 (OMIM: 600538) peroxiredoxin-2 [Homo sap ( 198) 1332 353.6 1.2e-97
NP_001189360 (OMIM: 176763) peroxiredoxin-1 [Homo  ( 199) 1101 293.5 1.5e-79
NP_859047 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 1101 293.5 1.5e-79
NP_002565 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 1101 293.5 1.5e-79
NP_859048 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 1101 293.5 1.5e-79
NP_006397 (OMIM: 300927) peroxiredoxin-4 precursor ( 271)  957 256.2 3.5e-68
XP_005274495 (OMIM: 300927) PREDICTED: peroxiredox ( 257)  953 255.1   7e-68
XP_016884719 (OMIM: 300927) PREDICTED: peroxiredox ( 350)  929 248.9 6.9e-66
XP_016884720 (OMIM: 300927) PREDICTED: peroxiredox ( 336)  925 247.9 1.4e-65
NP_006784 (OMIM: 604769) thioredoxin-dependent per ( 256)  881 236.4   3e-62
NP_001289201 (OMIM: 604769) thioredoxin-dependent  ( 198)  549 150.0 2.3e-36
NP_004896 (OMIM: 602316) peroxiredoxin-6 [Homo sap ( 224)  189 56.5 3.8e-08
NP_036226 (OMIM: 606583) peroxiredoxin-5, mitochon ( 214)  125 39.8  0.0037


>>NP_005800 (OMIM: 600538) peroxiredoxin-2 [Homo sapiens  (198 aa)
 initn: 1332 init1: 1332 opt: 1332  Z-score: 1873.9  bits: 353.6 E(85289): 1.2e-97
Smith-Waterman score: 1332; 100.0% identity (100.0% similar) in 198 aa overlap (1-198:1-198)

               10        20        30        40        50        60
pF1KB3 MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 RAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGS
              130       140       150       160       170       180

              190        
pF1KB3 DTIKPNVDDSKEYFSKHN
       ::::::::::::::::::
NP_005 DTIKPNVDDSKEYFSKHN
              190        

>>NP_001189360 (OMIM: 176763) peroxiredoxin-1 [Homo sapi  (199 aa)
 initn: 1099 init1: 1002 opt: 1101  Z-score: 1549.4  bits: 293.5 E(85289): 1.5e-79
Smith-Waterman score: 1101; 77.8% identity (96.0% similar) in 198 aa overlap (1-197:1-198)

               10        20         30        40        50         
pF1KB3 MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS
       :.::::.::.:::.::::::. :: ::...::::::::::.:::::::::::::::::::
NP_001 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB3 NRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLK
       .:::.:.::.:.:.:.::::.: ::::.:::.:.:::::.::::..:  : ...::::::
NP_001 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB3 TDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPG
       .::::..::::::: ::.:::::::::::::::::.::::::::.::.::::::::::::
NP_001 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
              130       140       150       160       170       180

     180       190        
pF1KB3 SDTIKPNVDDSKEYFSKHN
       ::::::.:. :::::::. 
NP_001 SDTIKPDVQKSKEYFSKQK
              190         

>>NP_859047 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens  (199 aa)
 initn: 1099 init1: 1002 opt: 1101  Z-score: 1549.4  bits: 293.5 E(85289): 1.5e-79
Smith-Waterman score: 1101; 77.8% identity (96.0% similar) in 198 aa overlap (1-197:1-198)

               10        20         30        40        50         
pF1KB3 MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS
       :.::::.::.:::.::::::. :: ::...::::::::::.:::::::::::::::::::
NP_859 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB3 NRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLK
       .:::.:.::.:.:.:.::::.: ::::.:::.:.:::::.::::..:  : ...::::::
NP_859 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB3 TDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPG
       .::::..::::::: ::.:::::::::::::::::.::::::::.::.::::::::::::
NP_859 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
              130       140       150       160       170       180

     180       190        
pF1KB3 SDTIKPNVDDSKEYFSKHN
       ::::::.:. :::::::. 
NP_859 SDTIKPDVQKSKEYFSKQK
              190         

>>NP_002565 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens  (199 aa)
 initn: 1099 init1: 1002 opt: 1101  Z-score: 1549.4  bits: 293.5 E(85289): 1.5e-79
Smith-Waterman score: 1101; 77.8% identity (96.0% similar) in 198 aa overlap (1-197:1-198)

               10        20         30        40        50         
pF1KB3 MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS
       :.::::.::.:::.::::::. :: ::...::::::::::.:::::::::::::::::::
NP_002 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB3 NRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLK
       .:::.:.::.:.:.:.::::.: ::::.:::.:.:::::.::::..:  : ...::::::
NP_002 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB3 TDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPG
       .::::..::::::: ::.:::::::::::::::::.::::::::.::.::::::::::::
NP_002 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
              130       140       150       160       170       180

     180       190        
pF1KB3 SDTIKPNVDDSKEYFSKHN
       ::::::.:. :::::::. 
NP_002 SDTIKPDVQKSKEYFSKQK
              190         

>>NP_859048 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens  (199 aa)
 initn: 1099 init1: 1002 opt: 1101  Z-score: 1549.4  bits: 293.5 E(85289): 1.5e-79
Smith-Waterman score: 1101; 77.8% identity (96.0% similar) in 198 aa overlap (1-197:1-198)

               10        20         30        40        50         
pF1KB3 MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS
       :.::::.::.:::.::::::. :: ::...::::::::::.:::::::::::::::::::
NP_859 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB3 NRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLK
       .:::.:.::.:.:.:.::::.: ::::.:::.:.:::::.::::..:  : ...::::::
NP_859 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB3 TDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPG
       .::::..::::::: ::.:::::::::::::::::.::::::::.::.::::::::::::
NP_859 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
              130       140       150       160       170       180

     180       190        
pF1KB3 SDTIKPNVDDSKEYFSKHN
       ::::::.:. :::::::. 
NP_859 SDTIKPDVQKSKEYFSKQK
              190         

>>NP_006397 (OMIM: 300927) peroxiredoxin-4 precursor [Ho  (271 aa)
 initn: 960 init1: 944 opt: 957  Z-score: 1345.0  bits: 256.2 E(85289): 3.5e-68
Smith-Waterman score: 957; 70.5% identity (90.2% similar) in 193 aa overlap (6-198:79-271)

                                        10        20        30     
pF1KB3                          MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKG
                                     :.:.:::: ...:::.:: :::.::.::.:
NP_006 EECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRG
       50        60        70        80        90       100        

          40        50        60        70        80        90     
pF1KB3 KYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGG
       ::.:.::::::::::::::::::..: :.::... ::.. ::::::::::::::::..::
NP_006 KYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGG
      110       120       130       140       150       160        

         100       110       120       130       140       150     
pF1KB3 LGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEA
       :::. ::::.:.:...:.::::   : : . ::::::: ::.:::::.:::::::::::.
NP_006 LGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDET
      170       180       190       200       210       220        

         160       170       180       190        
pF1KB3 LRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN
       :::::::::::.:::::::::::::.:: :.   . .::.: :
NP_006 LRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
      230       240       250       260       270 

>>XP_005274495 (OMIM: 300927) PREDICTED: peroxiredoxin-4  (257 aa)
 initn: 960 init1: 944 opt: 953  Z-score: 1339.7  bits: 255.1 E(85289): 7e-68
Smith-Waterman score: 953; 69.6% identity (89.7% similar) in 194 aa overlap (5-198:64-257)

                                         10        20        30    
pF1KB3                           MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYK
                                     :. ..:::: ...:::.:: :::.::.::.
XP_005 EAREGEDWEREPPRQRPPIYEPPESEELPDNVMVSKPAPYWEGTAVIDGEFKELKLTDYR
            40        50        60        70        80        90   

           40        50        60        70        80        90    
pF1KB3 GKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEG
       :::.:.::::::::::::::::::..: :.::... ::.. ::::::::::::::::..:
XP_005 GKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQG
           100       110       120       130       140       150   

          100       110       120       130       140       150    
pF1KB3 GLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDE
       ::::. ::::.:.:...:.::::   : : . ::::::: ::.:::::.:::::::::::
XP_005 GLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDE
           160       170       180       190       200       210   

          160       170       180       190        
pF1KB3 ALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN
       .:::::::::::.:::::::::::::.:: :.   . .::.: :
XP_005 TLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
           220       230       240       250       

>>XP_016884719 (OMIM: 300927) PREDICTED: peroxiredoxin-4  (350 aa)
 initn: 916 init1: 916 opt: 929  Z-score: 1303.9  bits: 248.9 E(85289): 6.9e-66
Smith-Waterman score: 929; 73.0% identity (92.7% similar) in 178 aa overlap (6-183:79-256)

                                        10        20        30     
pF1KB3                          MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKG
                                     :.:.:::: ...:::.:: :::.::.::.:
XP_016 EECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVIDGEFKELKLTDYRG
       50        60        70        80        90       100        

          40        50        60        70        80        90     
pF1KB3 KYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGG
       ::.:.::::::::::::::::::..: :.::... ::.. ::::::::::::::::..::
XP_016 KYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQGG
      110       120       130       140       150       160        

         100       110       120       130       140       150     
pF1KB3 LGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEA
       :::. ::::.:.:...:.::::   : : . ::::::: ::.:::::.:::::::::::.
XP_016 LGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDET
      170       180       190       200       210       220        

         160       170       180       190                         
pF1KB3 LRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN                 
       :::::::::::.:::::::::::::.:.                                
XP_016 LRLVQAFQYTDKHGEVCPAGWKPGSETVSIYICFYVELMVRVEKNAGRAQWLTPVIPALW
      230       240       250       260       270       280        

>>XP_016884720 (OMIM: 300927) PREDICTED: peroxiredoxin-4  (336 aa)
 initn: 916 init1: 916 opt: 925  Z-score: 1298.6  bits: 247.9 E(85289): 1.4e-65
Smith-Waterman score: 925; 72.1% identity (92.2% similar) in 179 aa overlap (5-183:64-242)

                                         10        20        30    
pF1KB3                           MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYK
                                     :. ..:::: ...:::.:: :::.::.::.
XP_016 EAREGEDWEREPPRQRPPIYEPPESEELPDNVMVSKPAPYWEGTAVIDGEFKELKLTDYR
            40        50        60        70        80        90   

           40        50        60        70        80        90    
pF1KB3 GKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEG
       :::.:.::::::::::::::::::..: :.::... ::.. ::::::::::::::::..:
XP_016 GKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQG
           100       110       120       130       140       150   

          100       110       120       130       140       150    
pF1KB3 GLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDE
       ::::. ::::.:.:...:.::::   : : . ::::::: ::.:::::.:::::::::::
XP_016 GLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDE
           160       170       180       190       200       210   

          160       170       180       190                        
pF1KB3 ALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN                
       .:::::::::::.:::::::::::::.:.                               
XP_016 TLRLVQAFQYTDKHGEVCPAGWKPGSETVSIYICFYVELMVRVEKNAGRAQWLTPVIPAL
           220       230       240       250       260       270   

>>NP_006784 (OMIM: 604769) thioredoxin-dependent peroxid  (256 aa)
 initn: 879 init1: 879 opt: 881  Z-score: 1238.6  bits: 236.4 E(85289): 3e-62
Smith-Waterman score: 881; 65.4% identity (89.0% similar) in 191 aa overlap (8-198:65-255)

                                      10        20        30       
pF1KB3                        MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKY
                                     . . :: ::.::::.: ::...:.:.::::
NP_006 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKY
           40        50        60        70        80        90    

        40        50        60        70        80        90       
pF1KB3 VVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLG
       .:::::::::::::::::.:::..:..:. ..:::..:::::.:.::::::::::.::::
NP_006 LVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLG
          100       110       120       130       140       150    

       100       110       120       130       140       150       
pF1KB3 PLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALR
        .:: ::.:.:...:.:::::    :.: ::::::: .::.....::::::::::.:.::
NP_006 HMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLR
          160       170       180       190       200       210    

       160       170       180       190         
pF1KB3 LVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN 
       ::.::::.. :::::::.: : : ::::.   :::::.: : 
NP_006 LVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
          220       230       240       250      




198 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:14:13 2016 done: Sat Nov  5 05:14:14 2016
 Total Scan time:  5.860 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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