FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1064, 100 aa 1>>>pF1KE1064 100 - 100 aa - 100 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2446+/-0.000696; mu= 9.9856+/- 0.042 mean_var=62.7368+/-12.535, 0's: 0 Z-trim(109.6): 27 B-trim: 428 in 1/52 Lambda= 0.161925 statistics sampled from 10990 (11012) to 10990 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.338), width: 16 Scan time: 1.150 The best scores are: opt bits E(32554) CCDS88.1 VAMP3 gene_id:9341|Hs108|chr1 ( 100) 646 158.6 5.8e-40 CCDS41740.1 VAMP1 gene_id:6843|Hs108|chr12 ( 118) 463 115.9 4.9e-27 CCDS32561.1 VAMP2 gene_id:6844|Hs108|chr17 ( 116) 461 115.4 6.7e-27 CCDS82064.1 VAMP2 gene_id:6844|Hs108|chr17 ( 118) 461 115.4 6.8e-27 CCDS44809.1 VAMP1 gene_id:6843|Hs108|chr12 ( 116) 457 114.5 1.3e-26 CCDS73422.1 VAMP1 gene_id:6843|Hs108|chr12 ( 116) 457 114.5 1.3e-26 CCDS31731.1 VAMP1 gene_id:6843|Hs108|chr12 ( 117) 457 114.5 1.3e-26 CCDS53430.1 VAMP4 gene_id:8674|Hs108|chr1 ( 140) 280 73.2 4.2e-14 CCDS1298.1 VAMP4 gene_id:8674|Hs108|chr1 ( 141) 280 73.2 4.2e-14 >>CCDS88.1 VAMP3 gene_id:9341|Hs108|chr1 (100 aa) initn: 646 init1: 646 opt: 646 Z-score: 830.9 bits: 158.6 E(32554): 5.8e-40 Smith-Waterman score: 646; 100.0% identity (100.0% similar) in 100 aa overlap (1-100:1-100) 10 20 30 40 50 60 pF1KE1 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS88 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQF 10 20 30 40 50 60 70 80 90 100 pF1KE1 ETSAAKLKRKYWWKNCKMWAIGITVLVIFIIIIIVWVVSS :::::::::::::::::::::::::::::::::::::::: CCDS88 ETSAAKLKRKYWWKNCKMWAIGITVLVIFIIIIIVWVVSS 70 80 90 100 >>CCDS41740.1 VAMP1 gene_id:6843|Hs108|chr12 (118 aa) initn: 454 init1: 437 opt: 463 Z-score: 598.8 bits: 115.9 E(32554): 4.9e-27 Smith-Waterman score: 463; 73.1% identity (88.2% similar) in 93 aa overlap (4-96:23-115) 10 20 30 40 pF1KE1 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQ :: ::::::::: ::.:::::.:::::::::::: CCDS41 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 KLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGITVLVIFIIIIIVWVVSS ::::::::::::::::::::.:::::::::::::::: . .. .:....:... CCDS41 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT 70 80 90 100 110 >>CCDS32561.1 VAMP2 gene_id:6844|Hs108|chr17 (116 aa) initn: 500 init1: 455 opt: 461 Z-score: 596.4 bits: 115.4 E(32554): 6.7e-27 Smith-Waterman score: 461; 81.3% identity (85.7% similar) in 91 aa overlap (5-94:22-112) 10 20 30 40 pF1KE1 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKL : ::::::::: ::::::::::::::::::::::: CCDS32 MSATAATAPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 SELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAI-GITVLVIFIIIIIVWVVSS :::::::::::::::::::::::::::::::: :: : :. .:.::::. CCDS32 SELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST 70 80 90 100 110 >>CCDS82064.1 VAMP2 gene_id:6844|Hs108|chr17 (118 aa) initn: 511 init1: 455 opt: 461 Z-score: 596.3 bits: 115.4 E(32554): 6.8e-27 Smith-Waterman score: 461; 81.3% identity (85.7% similar) in 91 aa overlap (5-94:24-114) 10 20 30 40 pF1KE1 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQ : ::::::::: ::::::::::::::::::::: CCDS82 MDRSATAATAPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 KLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAI-GITVLVIFIIIIIVWVVSS :::::::::::::::::::::::::::::::::: :: : :. .:.::::. CCDS82 KLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST 70 80 90 100 110 >>CCDS44809.1 VAMP1 gene_id:6843|Hs108|chr12 (116 aa) initn: 437 init1: 437 opt: 457 Z-score: 591.3 bits: 114.5 E(32554): 1.3e-26 Smith-Waterman score: 457; 74.7% identity (87.9% similar) in 91 aa overlap (4-94:23-113) 10 20 30 40 pF1KE1 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQ :: ::::::::: ::.:::::.:::::::::::: CCDS44 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 KLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGITVLVIFIIIIIVWVVSS ::::::::::::::::::::.:::::::::::::::: . .. .:....:. CCDS44 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVRRD 70 80 90 100 110 >>CCDS73422.1 VAMP1 gene_id:6843|Hs108|chr12 (116 aa) initn: 437 init1: 437 opt: 457 Z-score: 591.3 bits: 114.5 E(32554): 1.3e-26 Smith-Waterman score: 457; 74.7% identity (87.9% similar) in 91 aa overlap (4-94:23-113) 10 20 30 40 pF1KE1 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQ :: ::::::::: ::.:::::.:::::::::::: CCDS73 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 KLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGITVLVIFIIIIIVWVVSS ::::::::::::::::::::.:::::::::::::::: . .. .:....:. CCDS73 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVRRG 70 80 90 100 110 >>CCDS31731.1 VAMP1 gene_id:6843|Hs108|chr12 (117 aa) initn: 453 init1: 437 opt: 457 Z-score: 591.3 bits: 114.5 E(32554): 1.3e-26 Smith-Waterman score: 457; 74.7% identity (87.9% similar) in 91 aa overlap (4-94:23-113) 10 20 30 40 pF1KE1 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQ :: ::::::::: ::.:::::.:::::::::::: CCDS31 MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQ 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 KLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGITVLVIFIIIIIVWVVSS ::::::::::::::::::::.:::::::::::::::: . .. .:....:. CCDS31 KLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVSKYR 70 80 90 100 110 >>CCDS53430.1 VAMP4 gene_id:8674|Hs108|chr1 (140 aa) initn: 296 init1: 265 opt: 280 Z-score: 366.6 bits: 73.2 E(32554): 4.2e-14 Smith-Waterman score: 280; 38.5% identity (79.2% similar) in 96 aa overlap (3-98:41-135) 10 20 30 pF1KE1 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVN .:: . : .....:::::::.:.:. : CCDS53 DDDVTGSVKSERRNLLEDDSDEEEDFFLGPSGPRFGP-RNDKIKHVQNQVDEVIDVMQEN 20 30 40 50 60 40 50 60 70 80 90 pF1KE1 VDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGITVLVIFIII . ::.:: ..:.::.:....:. .:. : . . .:.:..::..::. :: : .:.... CCDS53 ITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALVAAILLLV 70 80 90 100 110 120 100 pF1KE1 IIVWVVSS ::. .: CCDS53 IIILIVMKYRT 130 140 >>CCDS1298.1 VAMP4 gene_id:8674|Hs108|chr1 (141 aa) initn: 296 init1: 265 opt: 280 Z-score: 366.6 bits: 73.2 E(32554): 4.2e-14 Smith-Waterman score: 280; 38.5% identity (79.2% similar) in 96 aa overlap (3-98:42-136) 10 20 30 pF1KE1 MSTGPTAATGSNRRLQQTQNQVDEVVDIMRVN .:: . : .....:::::::.:.:. : CCDS12 DDVTGSVKSERRNLLEDDSDEEEDFFLRGPSGPRFGP-RNDKIKHVQNQVDEVIDVMQEN 20 30 40 50 60 70 40 50 60 70 80 90 pF1KE1 VDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGITVLVIFIII . ::.:: ..:.::.:....:. .:. : . . .:.:..::..::. :: : .:.... CCDS12 ITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALVAAILLLV 80 90 100 110 120 130 100 pF1KE1 IIVWVVSS ::. .: CCDS12 IIILIVMKYRT 140 100 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 02:42:18 2016 done: Sat Nov 5 02:42:18 2016 Total Scan time: 1.150 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]