Result of FASTA (omim) for pF1KB0937
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0937, 160 aa
  1>>>pF1KB0937 160 - 160 aa - 160 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.6728+/-0.000287; mu= 7.0711+/- 0.018
 mean_var=117.2497+/-23.875, 0's: 0 Z-trim(121.0): 73  B-trim: 1966 in 1/50
 Lambda= 0.118445
 statistics sampled from 36882 (37033) to 36882 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.434), width:  16
 Scan time:  5.510

The best scores are:                                      opt bits E(85289)
NP_001258822 (OMIM: 200110,209885,227260,607556) t ( 160) 1038 187.1 1.1e-47
NP_476527 (OMIM: 200110,209885,227260,607556) twis ( 160) 1038 187.1 1.1e-47
XP_011513798 (OMIM: 101400,123100,180750,601622) P ( 202)  655 121.7 6.5e-28
NP_000465 (OMIM: 101400,123100,180750,601622) twis ( 202)  655 121.7 6.5e-28
XP_006716679 (OMIM: 609067) PREDICTED: basic helix ( 201)  230 49.1 4.7e-06
NP_001073983 (OMIM: 609067) basic helix-loop-helix ( 201)  230 49.1 4.7e-06
NP_005089 (OMIM: 603628) musculin [Homo sapiens]   ( 206)  226 48.4 7.7e-06
NP_835455 (OMIM: 607194,609069,615935) pancreas tr ( 328)  227 48.7 9.8e-06
NP_004600 (OMIM: 601010) transcription factor 15 [ ( 199)  213 46.1 3.5e-05
NP_005412 (OMIM: 186855,613065) T-cell acute lymph ( 108)  207 44.9 4.4e-05
NP_003197 (OMIM: 603306) transcription factor 21 [ ( 179)  210 45.6 4.6e-05
NP_938206 (OMIM: 603306) transcription factor 21 [ ( 179)  210 45.6 4.6e-05
NP_068808 (OMIM: 602407) heart- and neural crest d ( 217)  205 44.8 9.6e-05
NP_001277335 (OMIM: 187040,613065) T-cell acute ly ( 172)  196 43.2 0.00023
XP_016857682 (OMIM: 187040,613065) PREDICTED: T-ce ( 172)  196 43.2 0.00023
NP_005589 (OMIM: 162360) helix-loop-helix protein  ( 133)  190 42.1 0.00039
XP_016857678 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  196 43.4 0.00039
NP_001277332 (OMIM: 187040,613065) T-cell acute ly ( 331)  196 43.4 0.00039
XP_016857676 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  196 43.4 0.00039
XP_016857680 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  196 43.4 0.00039
NP_001274276 (OMIM: 187040,613065) T-cell acute ly ( 331)  196 43.4 0.00039
NP_001277333 (OMIM: 187040,613065) T-cell acute ly ( 331)  196 43.4 0.00039
NP_003180 (OMIM: 187040,613065) T-cell acute lymph ( 331)  196 43.4 0.00039
XP_005271217 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  196 43.4 0.00039
XP_016857679 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  196 43.4 0.00039
XP_016857677 (OMIM: 187040,613065) PREDICTED: T-ce ( 331)  196 43.4 0.00039
NP_001277334 (OMIM: 187040,613065) T-cell acute ly ( 331)  196 43.4 0.00039
NP_002491 (OMIM: 125853,601724,606394) neurogenic  ( 356)  196 43.4 0.00041
NP_067014 (OMIM: 611635) neurogenic differentiatio ( 331)  194 43.1 0.00049
NP_073565 (OMIM: 611513) neurogenic differentiatio ( 337)  190 42.4  0.0008
XP_005259969 (OMIM: 151440) PREDICTED: protein lyl ( 206)  186 41.5 0.00088
NP_005163 (OMIM: 601461) protein atonal homolog 1  ( 354)  189 42.2 0.00094
NP_005574 (OMIM: 151440) protein lyl-1 [Homo sapie ( 280)  186 41.6  0.0011
NP_803238 (OMIM: 608606) class A basic helix-loop- ( 189)  183 41.0  0.0012
XP_016882306 (OMIM: 151440) PREDICTED: protein lyl ( 302)  186 41.7  0.0012
NP_076924 (OMIM: 606624) neurogenin-2 [Homo sapien ( 272)  185 41.5  0.0012
XP_005268588 (OMIM: 602406) PREDICTED: heart- and  ( 214)  183 41.0  0.0013
NP_004812 (OMIM: 602406) heart- and neural crest d ( 215)  183 41.0  0.0013
XP_016882305 (OMIM: 151440) PREDICTED: protein lyl ( 351)  186 41.7  0.0013
NP_006151 (OMIM: 601725) neurogenic differentiatio ( 382)  184 41.4  0.0018
XP_016871769 (OMIM: 604882,610370) PREDICTED: neur ( 214)  179 40.4  0.0021
NP_066279 (OMIM: 604882,610370) neurogenin-3 [Homo ( 214)  179 40.4  0.0021
NP_005590 (OMIM: 162361) helix-loop-helix protein  ( 135)  168 38.3  0.0053
NP_001104531 (OMIM: 162361) helix-loop-helix prote ( 135)  168 38.3  0.0053
NP_006152 (OMIM: 601726) neurogenin-1 [Homo sapien ( 237)  171 39.0  0.0058
NP_660161 (OMIM: 609875) protein atonal homolog 7  ( 152)  166 38.0  0.0074
NP_620450 (OMIM: 606385) oligodendrocyte transcrip ( 271)  169 38.7  0.0082


>>NP_001258822 (OMIM: 200110,209885,227260,607556) twist  (160 aa)
 initn: 1038 init1: 1038 opt: 1038  Z-score: 977.3  bits: 187.1 E(85289): 1.1e-47
Smith-Waterman score: 1038; 100.0% identity (100.0% similar) in 160 aa overlap (1-160:1-160)

               10        20        30        40        50        60
pF1KB0 MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 FEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQV
               70        80        90       100       110       120

              130       140       150       160
pF1KB0 LQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH
       ::::::::::::::::::::::::::::::::::::::::
NP_001 LQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH
              130       140       150       160

>>NP_476527 (OMIM: 200110,209885,227260,607556) twist-re  (160 aa)
 initn: 1038 init1: 1038 opt: 1038  Z-score: 977.3  bits: 187.1 E(85289): 1.1e-47
Smith-Waterman score: 1038; 100.0% identity (100.0% similar) in 160 aa overlap (1-160:1-160)

               10        20        30        40        50        60
pF1KB0 MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 FEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 FEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQV
               70        80        90       100       110       120

              130       140       150       160
pF1KB0 LQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH
       ::::::::::::::::::::::::::::::::::::::::
NP_476 LQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH
              130       140       150       160

>>XP_011513798 (OMIM: 101400,123100,180750,601622) PREDI  (202 aa)
 initn: 794 init1: 640 opt: 655  Z-score: 622.2  bits: 121.7 E(85289): 6.5e-28
Smith-Waterman score: 713; 66.7% identity (75.0% similar) in 192 aa overlap (10-160:11-202)

                10         20            30        40              
pF1KB0  MEEGSSSPVSPVD-SLGTSEEELERQ-P---KRFGRKRRYSKKSS--------------
                 ::.: ::..:::: .:: :   :: ::::: :..:.              
XP_011 MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGV
               10        20        30        40        50        60

                   50                          60        70        
pF1KB0 ----EDGSPTPGKRGKK------------------GSPSAQSFEELQSQRILANVRERQR
           : :::. ::::::                  :. : ::.::::.::..::::::::
XP_011 GGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQR
               70        80        90       100       110       120

       80        90       100       110       120       130        
pF1KB0 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAH
       :::::::::::::::::::::::::::::::::::::::::::::::.:.::.:::::::
XP_011 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH
              130       140       150       160       170       180

      140       150       160
pF1KB0 ERLSYAFSVWRMEGAWSMSASH
       ::::::::::::::::::::::
XP_011 ERLSYAFSVWRMEGAWSMSASH
              190       200  

>>NP_000465 (OMIM: 101400,123100,180750,601622) twist-re  (202 aa)
 initn: 794 init1: 640 opt: 655  Z-score: 622.2  bits: 121.7 E(85289): 6.5e-28
Smith-Waterman score: 713; 66.7% identity (75.0% similar) in 192 aa overlap (10-160:11-202)

                10         20            30        40              
pF1KB0  MEEGSSSPVSPVD-SLGTSEEELERQ-P---KRFGRKRRYSKKSS--------------
                 ::.: ::..:::: .:: :   :: ::::: :..:.              
NP_000 MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGV
               10        20        30        40        50        60

                   50                          60        70        
pF1KB0 ----EDGSPTPGKRGKK------------------GSPSAQSFEELQSQRILANVRERQR
           : :::. ::::::                  :. : ::.::::.::..::::::::
NP_000 GGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQR
               70        80        90       100       110       120

       80        90       100       110       120       130        
pF1KB0 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAH
       :::::::::::::::::::::::::::::::::::::::::::::::.:.::.:::::::
NP_000 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH
              130       140       150       160       170       180

      140       150       160
pF1KB0 ERLSYAFSVWRMEGAWSMSASH
       ::::::::::::::::::::::
NP_000 ERLSYAFSVWRMEGAWSMSASH
              190       200  

>>XP_006716679 (OMIM: 609067) PREDICTED: basic helix-loo  (201 aa)
 initn: 201 init1: 135 opt: 230  Z-score: 229.7  bits: 49.1 E(85289): 4.7e-06
Smith-Waterman score: 230; 38.3% identity (64.8% similar) in 128 aa overlap (7-133:20-143)

                            10        20        30        40       
pF1KB0              MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTP
                          ::.:  .. :..    ...: :    :   . . . ..   
XP_006 MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAG---
               10        20        30        40        50          

        50        60        70        80        90        100      
pF1KB0 GKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQT
       :.:.  :.:...  .:   ::  ::.:::.::.:.: ::.::: .::: :.: :::::.:
XP_006 GRRAGGGGPGGRPGRE-PRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIET
        60        70         80        90       100       110      

        110       120       130       140       150       160      
pF1KB0 LKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH      
       :.::. ::. : .:: . :  .    :                                 
XP_006 LRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQPK
        120       130       140       150       160       170      

>>NP_001073983 (OMIM: 609067) basic helix-loop-helix tra  (201 aa)
 initn: 201 init1: 135 opt: 230  Z-score: 229.7  bits: 49.1 E(85289): 4.7e-06
Smith-Waterman score: 230; 38.3% identity (64.8% similar) in 128 aa overlap (7-133:20-143)

                            10        20        30        40       
pF1KB0              MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTP
                          ::.:  .. :..    ...: :    :   . . . ..   
NP_001 MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAARCGLQGARRRAG---
               10        20        30        40        50          

        50        60        70        80        90        100      
pF1KB0 GKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQT
       :.:.  :.:...  .:   ::  ::.:::.::.:.: ::.::: .::: :.: :::::.:
NP_001 GRRAGGGGPGGRPGRE-PRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIET
        60        70         80        90       100       110      

        110       120       130       140       150       160      
pF1KB0 LKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH      
       :.::. ::. : .:: . :  .    :                                 
NP_001 LRLASSYISHLGNVLLAGEACGDGQPCHSGPAFFHAARAGSPPPPPPPPPARDGENTQPK
        120       130       140       150       160       170      

>>NP_005089 (OMIM: 603628) musculin [Homo sapiens]        (206 aa)
 initn: 217 init1: 116 opt: 226  Z-score: 225.9  bits: 48.4 E(85289): 7.7e-06
Smith-Waterman score: 234; 36.6% identity (58.8% similar) in 153 aa overlap (7-147:37-184)

                                       10        20                
pF1KB0                         MEEGSSSPVSPVDSLGTSEEELERQPKRF-------
                                     : .:: :. .. ::. . . .:        
NP_005 SDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGS
         10        20        30        40        50        60      

        30        40         50        60         70        80     
pF1KB0 --GRKRRYSKKSSEDGSP-TPGKRGKKGSPSAQSFEEL-QSQRILANVRERQRTQSLNEA
         : ::.  . ..  :.  . :  :::  :.  :  :  ::::  ::.::: : . :..:
NP_005 AEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKA
         70        80        90       100       110       120      

          90        100       110       120       130       140    
pF1KB0 FAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYA
       :. :.  .: .: : ::::..::.::. ::  : :.:: :...:     .::    :.. 
NP_005 FSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN-----GYVHPVNLTWP
        130       140       150       160       170            180 

          150       160         
pF1KB0 FSVWRMEGAWSMSASH         
       : :                      
NP_005 FVVSGRPDSDTKEVSAANRLCGTTA
             190       200      

>>NP_835455 (OMIM: 607194,609069,615935) pancreas transc  (328 aa)
 initn: 235 init1: 146 opt: 227  Z-score: 223.9  bits: 48.7 E(85289): 9.8e-06
Smith-Waterman score: 227; 48.9% identity (70.0% similar) in 90 aa overlap (44-124:133-222)

            20        30        40        50                60     
pF1KB0 SLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSA--------QSFEELQ
                                     ::    :: .:. .:        .:  :::
NP_835 ETGAPPGGFPYSPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQ
            110       120       130       140       150       160  

          70        80        90       100        110       120    
pF1KB0 SQRILANVRERQRTQSLNEAFAALRKIIPTLPSDK-LSKIQTLKLAARYIDFLYQVLQSD
       . :  ::::::.: ::.:.:: .::. ::::: .: :::..::.::  ::.:: ...:.:
NP_835 QLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQAD
            170       180       190       200       210       220  

          130       140       150       160                        
pF1KB0 EMDNKMTSCSYVAHERLSYAFSVWRMEGAWSMSASH                        
                                                                   
NP_835 LPLRGGGAGGCGGPGGGGRLGGDSPGSQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLS
            230       240       250       260       270       280  

>>NP_004600 (OMIM: 601010) transcription factor 15 [Homo  (199 aa)
 initn: 222 init1: 143 opt: 213  Z-score: 214.1  bits: 46.1 E(85289): 3.5e-05
Smith-Waterman score: 213; 48.8% identity (68.6% similar) in 86 aa overlap (45-128:51-136)

           20        30        40        50        60        70    
pF1KB0 LGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEELQSQRILANVR
                                     : ::   . :. .. .   .  ::  ::.:
NP_004 LSEDEENRSESDASDQSFGCCEGPEAARRGPGPGGGRRAGGGGGAGPVVVVRQRQAANAR
               30        40        50        60        70        80

           80        90        100       110       120        130  
pF1KB0 ERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ-SDEMDNKMTS
       ::.::::.: ::.::: .::: : : :::::.::.::. ::  : .::  .:  :.    
NP_004 ERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLGDSADDGQPC
               90       100       110       120       130       140

            140       150       160                               
pF1KB0 CSYVAHERLSYAFSVWRMEGAWSMSASH                               
                                                                  
NP_004 FRAAGSAKGAVPAAADGGRQPRSICTFCLSNQRKGGGRRDLGGSCLKVRGVAPLRGPRR
              150       160       170       180       190         

>>NP_005412 (OMIM: 186855,613065) T-cell acute lymphocyt  (108 aa)
 initn: 136 init1: 136 opt: 207  Z-score: 212.3  bits: 44.9 E(85289): 4.4e-05
Smith-Waterman score: 207; 59.6% identity (82.5% similar) in 57 aa overlap (66-121:2-58)

          40        50        60        70        80        90     
pF1KB0 SKKSSEDGSPTPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPT
                                     ...:..:.::: : :..: ::: :::.:::
NP_005                              MTRKIFTNTRERWRQQNVNSAFAKLRKLIPT
                                            10        20        30 

         100        110       120       130       140       150    
pF1KB0 LPSDK-LSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYAFSVWRMEGAW
        : :: ::: .::.:: :::.:: .::                                 
NP_005 HPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDRT
              40        50        60        70        80        90 




160 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 17:20:50 2016 done: Sat Nov  5 17:20:51 2016
 Total Scan time:  5.510 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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