Result of FASTA (omim) for pF1KB7682
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7682, 406 aa
  1>>>pF1KB7682 406 - 406 aa - 406 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.3037+/-0.000452; mu= -22.0431+/- 0.028
 mean_var=728.8475+/-155.715, 0's: 0 Z-trim(126.4): 166  B-trim: 858 in 1/60
 Lambda= 0.047507
 statistics sampled from 51931 (52184) to 51931 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.847), E-opt: 0.2 (0.612), width:  16
 Scan time: 11.300

The best scores are:                                      opt bits E(85289)
NP_612157 (OMIM: 606903) pygopus homolog 2 [Homo s ( 406) 3000 220.1 7.7e-57
NP_056432 (OMIM: 606902) pygopus homolog 1 isoform ( 419)  556 52.6 2.1e-06
NP_001317255 (OMIM: 606902) pygopus homolog 1 isof ( 419)  556 52.6 2.1e-06
XP_011519748 (OMIM: 606902) PREDICTED: pygopus hom ( 419)  556 52.6 2.1e-06
NP_006239 (OMIM: 168810) basic salivary proline-ri ( 416)  444 44.9 0.00043
NP_005030 (OMIM: 180989) basic salivary proline-ri ( 331)  394 41.4  0.0039


>>NP_612157 (OMIM: 606903) pygopus homolog 2 [Homo sapie  (406 aa)
 initn: 3000 init1: 3000 opt: 3000  Z-score: 1141.4  bits: 220.1 E(85289): 7.7e-57
Smith-Waterman score: 3000; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406)

               10        20        30        40        50        60
pF1KB7 MAASAPPPPDKLEGGGGPAPPPAPPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MAASAPPPPDKLEGGGGPAPPPAPPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 FAPPPTPMVDHLVASNPFEDDFGAPKVGVAAPPFLGSPVPFGGFRVQGGMAGQVPPGYST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 FAPPPTPMVDHLVASNPFEDDFGAPKVGVAAPPFLGSPVPFGGFRVQGGMAGQVPPGYST
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 GGGGGPQPLRRQPPPFPPNPMGPAFNMPPQGPGYPPPGNMNFPSQPFNQPLGQNFSPPSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 GGGGGPQPLRRQPPPFPPNPMGPAFNMPPQGPGYPPPGNMNFPSQPFNQPLGQNFSPPSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 QMMPGPVGGFGPMISPTMGQPPRAELGPPSLSQRFAQPGAPFGPSPLQRPGQGLPSLPPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 QMMPGPVGGFGPMISPTMGQPPRAELGPPSLSQRFAQPGAPFGPSPLQRPGQGLPSLPPN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 TSPFPGPDPGFPGPGGEDGGKPLNPPASTAFPQEPHSGSPAAAVNGNQPSFPPNSSGRGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 TSPFPGPDPGFPGPGGEDGGKPLNPPASTAFPQEPHSGSPAAAVNGNQPSFPPNSSGRGG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 GTPDANSLAPPGKAGGGSGPQPPPGLVYPCGACRSEVNDDQDAILCEASCQKWFHRECTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 GTPDANSLAPPGKAGGGSGPQPPPGLVYPCGACRSEVNDDQDAILCEASCQKWFHRECTG
              310       320       330       340       350       360

              370       380       390       400      
pF1KB7 MTESAYGLLTTEASAVWACDLCLKTKEIQSVYIREGMGQLVAANDG
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MTESAYGLLTTEASAVWACDLCLKTKEIQSVYIREGMGQLVAANDG
              370       380       390       400      

>>NP_056432 (OMIM: 606902) pygopus homolog 1 isoform 1 [  (419 aa)
 initn: 634 init1: 407 opt: 556  Z-score: 236.0  bits: 52.6 E(85289): 2.1e-06
Smith-Waterman score: 874; 37.6% identity (59.2% similar) in 431 aa overlap (2-405:3-418)

                10        20        30        40        50         
pF1KB7  MAASAPPPPDKLEGGGGPAPPPAPPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLT
         : ..: :  :. . ::        :     :  :.:. ::.::.::.:::::..  :.
NP_056 MPAENSPAPAYKVSSHGGD-------SGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLS
               10               20        30        40        50   

      60        70        80          90       100        110      
pF1KB7 EFAPPPTPMVDHLVASNPFEDDFG--APKVGVAAPPFLGSPVP-FGGFRVQGGMAGQVPP
       :.::::.:  :::::.:::.:...  . :   .. :.::   : :::. .   :  .:::
NP_056 EYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFR-MPPHVPP
            60        70        80        90       100        110  

        120       130       140       150       160       170      
pF1KB7 GYSTGGGGGPQPLRRQPPPFPPNPMGPAFNMPPQGPGYPPPGNMNFPSQPFNQPLGQNFS
        .:.   : :  :: :: ::: ::.: .:: : .. .. :  : .: .  .:. :.:: .
NP_056 RMSSPYCG-PYSLRNQPHPFPQNPLGMGFNRP-HAFNFGPHDNSSFGNPSYNNALSQNVN
            120        130       140        150       160       170

        180       190          200                 210       220   
pF1KB7 PPSGQMMPGPVGGFG---PMISPTMGQPPRAE----------LGPPSLSQRFAQPGAPFG
        :. ..  .:. .:.   :. .  ...:  :            .:   .. :  :   ::
NP_056 MPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFG
              180       190       200       210       220       230

               230        240       250       260       270        
pF1KB7 ----PSPLQRPGQG-LPSLPPNTSPFPGPDPGFPGPGGEDGGKPLNPPASTAFPQEPHSG
           : : :   ::   .   :.:  : :  ..    .... .  :   ..:  ::   .
NP_056 QAKAPPPKQDFTQGATKNTNQNSSAHP-PHLNMDDTVNQSNIELKNVNRNNAVNQENSRS
              240       250        260       270       280         

      280       290       300       310             320       330  
pF1KB7 SPAAAVNGNQPSFPPNSSGRGGGTPDANSLAPPGKAG------GGSGPQPPPGLVYPCGA
       : . :.:.:  .   :.  .  :. :: .    .:..      : :. .:    ::::: 
NP_056 SSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDP----VYPCGI
     290       300       310       320       330           340     

            340       350       360       370       380       390  
pF1KB7 CRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCLKTKEIQSVY
       : .::::::::::::::::::::: ::::::.::::::.::::::.:: :.  :..: . 
NP_056 CTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMR
         350       360       370       380       390       400     

            400      
pF1KB7 IREGMGQLVAANDG
        :: .:  ....: 
NP_056 TRETFGPSAVGSDA
         410         

>>NP_001317255 (OMIM: 606902) pygopus homolog 1 isoform   (419 aa)
 initn: 634 init1: 407 opt: 556  Z-score: 236.0  bits: 52.6 E(85289): 2.1e-06
Smith-Waterman score: 865; 38.7% identity (60.8% similar) in 401 aa overlap (32-405:26-418)

              10        20        30        40        50        60 
pF1KB7 AASAPPPPDKLEGGGGPAPPPAPPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTEF
                                     :  :.:. ::.::.::.:::::..  :.:.
NP_001      MSAEQEKDPISLKRVRGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEY
                    10        20        30        40        50     

              70        80          90       100        110        
pF1KB7 APPPTPMVDHLVASNPFEDDFG--APKVGVAAPPFLGSPVP-FGGFRVQGGMAGQVPPGY
       ::::.:  :::::.:::.:...  . :   .. :.::   : :::. .   :  .::: .
NP_001 APPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFR-MPPHVPPRM
          60        70        80        90       100        110    

      120       130       140       150       160       170        
pF1KB7 STGGGGGPQPLRRQPPPFPPNPMGPAFNMPPQGPGYPPPGNMNFPSQPFNQPLGQNFSPP
       :.   : :  :: :: ::: ::.: .:: : .. .. :  : .: .  .:. :.:: . :
NP_001 SSPYCG-PYSLRNQPHPFPQNPLGMGFNRP-HAFNFGPHDNSSFGNPSYNNALSQNVNMP
          120        130       140        150       160       170  

      180       190          200                 210       220     
pF1KB7 SGQMMPGPVGGFG---PMISPTMGQPPRAE----------LGPPSLSQRFAQPGAPFG--
       . ..  .:. .:.   :. .  ...:  :            .:   .. :  :   ::  
NP_001 NQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQA
            180       190       200       210       220       230  

             230        240       250       260       270       280
pF1KB7 --PSPLQRPGQG-LPSLPPNTSPFPGPDPGFPGPGGEDGGKPLNPPASTAFPQEPHSGSP
         : : :   ::   .   :.:  : :  ..    .... .  :   ..:  ::   .: 
NP_001 KAPPPKQDFTQGATKNTNQNSSAHP-PHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSS
            240       250        260       270       280       290 

              290       300       310             320       330    
pF1KB7 AAAVNGNQPSFPPNSSGRGGGTPDANSLAPPGKAG------GGSGPQPPPGLVYPCGACR
       . :.:.:  .   :.  .  :. :: .    .:..      : :. .:    ::::: : 
NP_001 TEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDP----VYPCGICT
             300       310       320       330           340       

          340       350       360       370       380       390    
pF1KB7 SEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCLKTKEIQSVYIR
       .::::::::::::::::::::: ::::::.::::::.::::::.:: :.  :..: .  :
NP_001 NEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTR
       350       360       370       380       390       400       

          400      
pF1KB7 EGMGQLVAANDG
       : .:  ....: 
NP_001 ETFGPSAVGSDA
       410         

>>XP_011519748 (OMIM: 606902) PREDICTED: pygopus homolog  (419 aa)
 initn: 634 init1: 407 opt: 556  Z-score: 236.0  bits: 52.6 E(85289): 2.1e-06
Smith-Waterman score: 865; 38.7% identity (60.8% similar) in 401 aa overlap (32-405:26-418)

              10        20        30        40        50        60 
pF1KB7 AASAPPPPDKLEGGGGPAPPPAPPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTEF
                                     :  :.:. ::.::.::.:::::..  :.:.
XP_011      MSAEQEKDPISLKRVRGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEY
                    10        20        30        40        50     

              70        80          90       100        110        
pF1KB7 APPPTPMVDHLVASNPFEDDFG--APKVGVAAPPFLGSPVP-FGGFRVQGGMAGQVPPGY
       ::::.:  :::::.:::.:...  . :   .. :.::   : :::. .   :  .::: .
XP_011 APPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFR-MPPHVPPRM
          60        70        80        90       100        110    

      120       130       140       150       160       170        
pF1KB7 STGGGGGPQPLRRQPPPFPPNPMGPAFNMPPQGPGYPPPGNMNFPSQPFNQPLGQNFSPP
       :.   : :  :: :: ::: ::.: .:: : .. .. :  : .: .  .:. :.:: . :
XP_011 SSPYCG-PYSLRNQPHPFPQNPLGMGFNRP-HAFNFGPHDNSSFGNPSYNNALSQNVNMP
          120        130       140        150       160       170  

      180       190          200                 210       220     
pF1KB7 SGQMMPGPVGGFG---PMISPTMGQPPRAE----------LGPPSLSQRFAQPGAPFG--
       . ..  .:. .:.   :. .  ...:  :            .:   .. :  :   ::  
XP_011 NQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQA
            180       190       200       210       220       230  

             230        240       250       260       270       280
pF1KB7 --PSPLQRPGQG-LPSLPPNTSPFPGPDPGFPGPGGEDGGKPLNPPASTAFPQEPHSGSP
         : : :   ::   .   :.:  : :  ..    .... .  :   ..:  ::   .: 
XP_011 KAPPPKQDFTQGATKNTNQNSSAHP-PHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSS
            240       250        260       270       280       290 

              290       300       310             320       330    
pF1KB7 AAAVNGNQPSFPPNSSGRGGGTPDANSLAPPGKAG------GGSGPQPPPGLVYPCGACR
       . :.:.:  .   :.  .  :. :: .    .:..      : :. .:    ::::: : 
XP_011 TEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDP----VYPCGICT
             300       310       320       330           340       

          340       350       360       370       380       390    
pF1KB7 SEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCLKTKEIQSVYIR
       .::::::::::::::::::::: ::::::.::::::.::::::.:: :.  :..: .  :
XP_011 NEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTR
       350       360       370       380       390       400       

          400      
pF1KB7 EGMGQLVAANDG
       : .:  ....: 
XP_011 ETFGPSAVGSDA
       410         

>>NP_006239 (OMIM: 168810) basic salivary proline-rich p  (416 aa)
 initn: 223 init1: 223 opt: 444  Z-score: 194.5  bits: 44.9 E(85289): 0.00043
Smith-Waterman score: 482; 32.1% identity (47.3% similar) in 349 aa overlap (6-324:72-395)

                                        10          20        30   
pF1KB7                          MAASAPPPPDKLEGGG--GPAPPPAPPSTGRKQGK
                                     :::: : .:    :   : .::  :. :: 
NP_006 QGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP
              50        60        70        80        90       100 

              40        50        60        70        80        90 
pF1KB7 A--GLQMKSPEKKRRKSNTQGPAYSHLTEFAPPPTPMVDHLVASNPFEDDFGAPKVGVAA
          : . .::..   : .   :  ..  . .::: :   .    .:  .  . :. :   
NP_006 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQ-GPPPPPGKPQ----GPPPQGGNKPQ-GPPP
             110       120       130        140           150      

             100       110       120         130       140         
pF1KB7 PPFLGSPVPFGGFRVQGGMAGQVPPGYSTGGG--GGPQPLRRQPPPFPPNPMGPAFNMPP
       :    .: : :  . .   ... :::   :    :: ::  . ::: : .:.::    ::
NP_006 PGKPQGPPPQGDNKSR---SSRSPPGKPQGPPPQGGNQP--QGPPPPPGKPQGP----PP
         160       170          180       190         200          

     150           160       170       180       190       200     
pF1KB7 QG---P-GYPPPGNMNFPSQPFNQPLGQNFSPPSGQMMPGPVGGFGPMISPTMGQPPRAE
       ::   : : ::::. . :    ..   .  :::.  . : : ::  :.  :    ::   
NP_006 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP---PPPGKP
        210       220       230       240       250          260   

         210           220              230           240       250
pF1KB7 LGPPSLSQRFAQ----PGAPFGPSPL-------QRPGQGLPSLPP----NTSPFPGPDPG
        :::  .    :    :: : :: :        .:   : :. ::    :    : : ::
NP_006 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG
           270       280       290       300       310       320   

               260       270       280       290       300         
pF1KB7 FP-GPGGEDGGKPLNPPASTAFPQEPHSGSPAAAVNGNQPSFPPNSSGRGGGTPDA---N
        : ::  . :.:: .::     : .:..  : .. .. .   ::   :.  : :.    :
NP_006 KPQGPPPQGGNKPQGPPP----PGKPQGPPPQGGSKSRSARSPP---GKPQGPPQQEGNN
           330       340           350       360          370      

        310        320       330       340       350       360     
pF1KB7 SLAPPGKAGGG-SGPQPPPGLVYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESA
         .::  :::. . :: ::                                         
NP_006 PQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ                    
        380       390       400       410                          

>>NP_005030 (OMIM: 180989) basic salivary proline-rich p  (331 aa)
 initn: 222 init1: 222 opt: 394  Z-score: 177.2  bits: 41.4 E(85289): 0.0039
Smith-Waterman score: 446; 34.2% identity (45.9% similar) in 342 aa overlap (1-324:31-310)

                                             10        20        30
pF1KB7                               MAASAPPPPDKLEGGGGPAPPPAPPSTGRK
                                     . :. :  :.  .::. :  :: ::  :. 
NP_005 MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSP-QGGNKPQGPPPPP--GKP
               10        20        30        40         50         

               40        50        60        70        80        90
pF1KB7 QGKAGLQMKSPEKKRRKSNTQGPAYSHLTEFAPPPTPMVDHLVASNPFEDDFGAPKVGVA
       ::        : .   :   :::         ::  :.     .  :  :   .:.    
NP_005 QGP-------PPQGGNK--PQGPP--------PPGKPQ-----GPPPQGDKSRSPR----
        60                 70                     80        90     

              100       110       120          130       140       
pF1KB7 APPFLGSPVPFGGFRVQGGMAGQVPPGYSTGGGGGPQPL---RRQPPPFPPNPMGPAFNM
       .::  :.:    :   :::   : ::    :   :: :    : : :: : .:.::    
NP_005 SPP--GKP---QGPPPQGGNQPQGPPP-PPGKPQGPPPQGGNRPQGPPPPGKPQGP----
                  100       110        120       130       140     

       150            160       170       180        190       200 
pF1KB7 PPQG-----PGYPPPGNMNFPSQPFNQPLGQNFSPPSGQMM-PGPVGGFGPMISPTMGQP
       ::::     :  ::   .. : :  ::: :    :: :. . : : ::  :.  :  :.:
NP_005 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP--PPPPGKPQGPPPQGGKKPQGPPPPGKP
             150       160       170         180       190         

             210           220       230       240       250       
pF1KB7 PRAELGPPSLSQ--RFAQ--PGAPFGPSPLQRPGQGLPSLPPNTSPFPGPDPGFP-GPGG
            :::  ..  : .:  :: : :: :    : . :. ::       : :: : ::  
NP_005 Q----GPPPQGDKSRSSQSPPGKPQGPPP---QGGNQPQGPP-------PPPGKPQGPPP
     200           210       220          230              240     

        260       270       280       290       300          310   
pF1KB7 EDGGKPLNPPASTAFPQEPHSGSPAAAVNGNQPSFPPNSSGRGGGTPDA---NSLAPPGK
       . :.:: .::     : .:. : :: . . .: .  :   :.  : :.    :  .::  
NP_005 QGGNKPQGPPP----PGKPQ-GPPAQGGSKSQSARSP--PGKPQGPPQQEGNNPQGPPPP
         250           260        270         280       290        

            320       330       340       350       360       370  
pF1KB7 AGGG-SGPQPPPGLVYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTE
       :::. . :: ::                                                
NP_005 AGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ                           
      300       310       320       330                            




406 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 10:04:44 2016 done: Sat Nov  5 10:04:46 2016
 Total Scan time: 11.300 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com