Result of FASTA (omim) for pF1KB5237
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5237, 295 aa
  1>>>pF1KB5237 295 - 295 aa - 295 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3891+/-0.00041; mu= 14.8649+/- 0.025
 mean_var=66.1944+/-13.004, 0's: 0 Z-trim(111.2): 48  B-trim: 124 in 1/55
 Lambda= 0.157639
 statistics sampled from 19668 (19714) to 19668 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.231), width:  16
 Scan time:  6.580

The best scores are:                                      opt bits E(85289)
NP_001984 (OMIM: 134390) tissue factor isoform 1 p ( 295) 1940 450.2 2.2e-126
NP_001171567 (OMIM: 134390) tissue factor isoform  ( 238) 1311 307.1 2.1e-83
NP_851826 (OMIM: 606648) interleukin-22 receptor s ( 231)  225 60.1 4.6e-09
NP_851827 (OMIM: 606648) interleukin-22 receptor s ( 130)  186 51.1 1.3e-06
NP_067081 (OMIM: 605457) interleukin-22 receptor s ( 574)  178 49.6 1.7e-05
XP_016866443 (OMIM: 605620) PREDICTED: interleukin ( 554)  143 41.7   0.004


>>NP_001984 (OMIM: 134390) tissue factor isoform 1 precu  (295 aa)
 initn: 1940 init1: 1940 opt: 1940  Z-score: 2389.9  bits: 450.2 E(85289): 2.2e-126
Smith-Waterman score: 1940; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295)

               10        20        30        40        50        60
pF1KB5 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 PVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 AGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVE
              190       200       210       220       230       240

              250       260       270       280       290     
pF1KB5 CMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
              250       260       270       280       290     

>>NP_001171567 (OMIM: 134390) tissue factor isoform 2 pr  (238 aa)
 initn: 1311 init1: 1311 opt: 1311  Z-score: 1618.3  bits: 307.1 E(85289): 2.1e-83
Smith-Waterman score: 1311; 100.0% identity (100.0% similar) in 198 aa overlap (1-198:1-198)

               10        20        30        40        50        60
pF1KB5 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 PVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 AGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 KDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVE
       ::::::::::::::::::                                          
NP_001 KDLIYTLYYWKSSSSGKKYSTSLELWYLWSSSLSSSWLYLYTSVERQEWGRAGRRTPH  
              190       200       210       220       230          

>>NP_851826 (OMIM: 606648) interleukin-22 receptor subun  (231 aa)
 initn: 162 init1:  81 opt: 225  Z-score: 283.6  bits: 60.1 E(85289): 4.6e-09
Smith-Waterman score: 225; 24.4% identity (61.1% similar) in 234 aa overlap (20-242:10-228)

               10        20        30        40        50        60
pF1KB5 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
                          .:... .. :::...: ...    . ..: ::..::.:.: 
NP_851           MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPG
                         10        20        30        40        50

                   70         80          90       100       110   
pF1KB5 PV----NQVYTVQISTKSG-DWKSK--CFYTTDTECDLTDEIVKDVKQTYLARVFSYPAG
        .    ..:: :: .  .  .::.:  :. : .  ::::.: ..:... : .::      
NP_851 RALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLTSE-TSDIQEPYYGRV------
               60        70        80        90        100         

           120       130       140       150       160        170  
pF1KB5 NVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVR-RNNTF
        . :.:: .:  .  .:.:::. ::.. .: .... ::. .. : ..      : ...  
NP_851 RAASAGSYSE--WSMTPRFTPWWETKI-DPPVMNITQVNGSLLVILHAPNLPYRYQKEKN
           110         120        130       140       150       160

            180       190       200       210          220         
pF1KB5 LSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDK---GENYCFSVQAVIPSRT
       .:..: .  .:.: ..  ..:   .. .  ....  ....      .::  ..   :   
NP_851 VSIEDYY--ELLYRVFIINNSLEKEQKVYEGAHR-AVEIEALTPHSSYCVVAEIYQP--M
                170       180       190        200       210       

     230       240       250       260       270       280         
pF1KB5 VNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKEN
       ..:.:  :  .:.                                               
NP_851 LDRRSQRSEERCVEIP                                            
         220       230                                             

>>NP_851827 (OMIM: 606648) interleukin-22 receptor subun  (130 aa)
 initn: 119 init1:  81 opt: 186  Z-score: 239.5  bits: 51.1 E(85289): 1.3e-06
Smith-Waterman score: 186; 31.0% identity (63.6% similar) in 129 aa overlap (20-141:10-129)

               10        20        30        40        50        60
pF1KB5 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
                          .:... .. :::...: ...    . ..: ::..::.:.: 
NP_851           MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPG
                         10        20        30        40        50

                   70         80          90       100       110   
pF1KB5 PV----NQVYTVQISTKSG-DWKSK--CFYTTDTECDLTDEIVKDVKQTYLARVFSYPAG
        .    ..:: :: .  .  .::.:  :. : .  ::::.: ..:... : .::      
NP_851 RALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLTSE-TSDIQEPYYGRV------
               60        70        80        90        100         

           120       130       140       150       160       170   
pF1KB5 NVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFL
        . :.:: .:  .  .:.:::. :   :                                
NP_851 RAASAGSYSE--WSMTPRFTPWWERAKGL                               
           110         120       130                               

>>NP_067081 (OMIM: 605457) interleukin-22 receptor subun  (574 aa)
 initn:  66 init1:  66 opt: 178  Z-score: 219.9  bits: 49.6 E(85289): 1.7e-05
Smith-Waterman score: 178; 22.3% identity (51.9% similar) in 260 aa overlap (18-270:2-246)

               10        20        30        40        50        60
pF1KB5 METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
                        ::::   . ...:. .    .    .. ..:.::..:: :.  
NP_067                 MRTLLTILTVGSLAAHAPEDPSDLLQHVKFQSSNFENILTWDSG
                               10        20        30        40    

                  70         80          90       100       110    
pF1KB5 PV---NQVYTVQISTKSG-DWKSK--CFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGN
       :    . ::... .: .  :: .:  :   :   :.:: : . .. . : ::: .  :: 
NP_067 PEGTPDTVYSIEYKTYGERDWVAKKGCQRITRKSCNLTVE-TGNLTELYYARVTAVSAG-
           50        60        70        80         90       100   

          120       130       140       150       160       170    
pF1KB5 VESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTF-L
              :.   . . .:.   .:.:  : .  . .:  .... :.   : .: ..   :
NP_067 -------GRSATKMTDRFSSLQHTTLKPPDVTCISKV-RSIQMIVHPTPTPIRAGDGHRL
                   110       120       130        140       150    

           180       190       200       210       220       230   
pF1KB5 SLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRK
       .:.:.: .::.: :    . .   . .  . .  .. .    ..  ...  .:  :  ..
NP_067 TLEDIF-HDLFYHLELQVNRTYQMHLGGKQREYEFFGLTPDTEFLGTIMICVP--TWAKE
          160        170       180       190       200         210 

           240       250       260       270       280       290   
pF1KB5 STDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLN
       :  .:  :  .   .    . . :: .: . .:: .:                       
NP_067 S--APYMCRVKTLPDRTWTYSFSGAFLFSMGFLVAVLCYLSYRYVTKPPAPPNSLNVQRV
               220       230       240       250       260         

                                                                   
pF1KB5 VS                                                          
                                                                   
NP_067 LTFQPLRFIQEHVLIPVFDLSGPSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQ
     270       280       290       300       310       320         

>>XP_016866443 (OMIM: 605620) PREDICTED: interleukin-20   (554 aa)
 initn:  80 init1:  52 opt: 143  Z-score: 177.1  bits: 41.7 E(85289): 0.004
Smith-Waterman score: 228; 26.1% identity (56.1% similar) in 314 aa overlap (1-294:1-289)

                10        20         30        40        50        
pF1KB5 METPAWPRV-PRPETAVARTLLLG-WVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWE
       :..:. : . : :   .   :: . :  : :  .::     :  :.:. : :.:..:.: 
XP_016 MRAPGRPALRPLPLPPLLLLLLAAPWGRA-VPCVSGGLPKPA--NITFLSINMKNVLQWT
               10        20         30        40          50       

           60        70            80        90       100       110
pF1KB5 P----KPVNQVYTVQISTKSGD--W--KSKCFYTTDTECDLTDEIVKDVKQTYLARVFSY
       :    . :. .::::   . :.  :  ::.:   . : :::. : ..: .. : :.: . 
XP_016 PPEGLQGVKVTYTVQYFIRYGQKKWLNKSECRNINRTYCDLSAE-TSDYEHQYYAKVKAI
        60        70        80        90       100        110      

              120       130       140        150       160         
pF1KB5 PAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQ-SFEQVGTKVNVTVEDERTLVRRN
         :.  :        . .: .: :.:::..: : .  . .. . .: .:. ..    .::
XP_016 -WGTKCSK-------WAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEK---WKRN
         120              130       140       150       160        

       170       180       190       200       210         220     
pF1KB5 --NTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLID--VDKGENYCFSVQAVI
         .  .:...... .: :..    ...:..  ..  ::. :.   .. .  ::  :.. .
XP_016 PEDLPVSMQQIYS-NLKYNVSVL-NTKSNRTWSQCVTNHTLVLTWLEPNTLYCVHVESFV
         170        180        190       200       210       220   

         230       240          250         260       270       280
pF1KB5 PSRTVNRKSTDSPVEC---MGQEKGEFRE--IFYIIGAVVFVVIILVIILAISLHKCRKA
       :.    :..  :  .:   . ....::.   ::. .  :  ....:  ... :..  :  
XP_016 PGPP--RRAQPSEKQCARTLKDQSSEFKAKIIFWYVLPVS-ITVFLFSVMGYSIY--RYI
             230       240       250       260        270          

              290                                                  
pF1KB5 GVGQSWKENSPLNVS                                             
        ::   ::. : :.                                              
XP_016 HVG---KEKHPANLILIYGNEFDKRFFVPAEKIVINFITLNISDDSKISHQDMSLLGKSS
      280          290       300       310       320       330     




295 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:12:15 2016 done: Fri Nov  4 20:12:16 2016
 Total Scan time:  6.580 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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