Result of FASTA (omim) for pF1KB8711
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8711, 482 aa
  1>>>pF1KB8711 482 - 482 aa - 482 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.8662+/-0.000396; mu= 11.1185+/- 0.025
 mean_var=110.0626+/-21.551, 0's: 0 Z-trim(114.9): 57  B-trim: 34 in 3/50
 Lambda= 0.122252
 statistics sampled from 24893 (24950) to 24893 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.293), width:  16
 Scan time:  8.530

The best scores are:                                      opt bits E(85289)
NP_001263407 (OMIM: 147625) islet cell autoantigen ( 482) 3204 576.1 7.6e-164
XP_016867610 (OMIM: 147625) PREDICTED: islet cell  ( 482) 3204 576.1 7.6e-164
XP_016867609 (OMIM: 147625) PREDICTED: islet cell  ( 482) 3204 576.1 7.6e-164
XP_016867608 (OMIM: 147625) PREDICTED: islet cell  ( 482) 3204 576.1 7.6e-164
XP_005249792 (OMIM: 147625) PREDICTED: islet cell  ( 482) 3204 576.1 7.6e-164
NP_004959 (OMIM: 147625) islet cell autoantigen 1  ( 483) 3192 574.0 3.3e-163
XP_016867606 (OMIM: 147625) PREDICTED: islet cell  ( 483) 3192 574.0 3.3e-163
NP_001129492 (OMIM: 147625) islet cell autoantigen ( 483) 3192 574.0 3.3e-163
XP_016867607 (OMIM: 147625) PREDICTED: islet cell  ( 483) 3192 574.0 3.3e-163
NP_071682 (OMIM: 147625) islet cell autoantigen 1  ( 483) 3192 574.0 3.3e-163
XP_016867614 (OMIM: 147625) PREDICTED: islet cell  ( 409) 2623 473.6 4.6e-133
XP_016867611 (OMIM: 147625) PREDICTED: islet cell  ( 409) 2623 473.6 4.6e-133
XP_016867613 (OMIM: 147625) PREDICTED: islet cell  ( 409) 2623 473.6 4.6e-133
XP_016867612 (OMIM: 147625) PREDICTED: islet cell  ( 409) 2623 473.6 4.6e-133
XP_011513653 (OMIM: 147625) PREDICTED: islet cell  ( 511) 2015 366.4 1.1e-100
XP_011513654 (OMIM: 147625) PREDICTED: islet cell  ( 511) 2015 366.4 1.1e-100
XP_016867605 (OMIM: 147625) PREDICTED: islet cell  ( 511) 2015 366.4 1.1e-100
XP_011513655 (OMIM: 147625) PREDICTED: islet cell  ( 511) 2015 366.4 1.1e-100
XP_011513652 (OMIM: 147625) PREDICTED: islet cell  ( 511) 2015 366.4 1.1e-100
XP_011513649 (OMIM: 147625) PREDICTED: islet cell  ( 512) 2003 364.3 4.6e-100
XP_011513650 (OMIM: 147625) PREDICTED: islet cell  ( 512) 2003 364.3 4.6e-100
XP_011513651 (OMIM: 147625) PREDICTED: islet cell  ( 512) 2003 364.3 4.6e-100
XP_011513647 (OMIM: 147625) PREDICTED: islet cell  ( 512) 2003 364.3 4.6e-100
XP_011513648 (OMIM: 147625) PREDICTED: islet cell  ( 512) 2003 364.3 4.6e-100
XP_011513656 (OMIM: 147625) PREDICTED: islet cell  ( 438) 1434 263.9 6.6e-70
XP_011513659 (OMIM: 147625) PREDICTED: islet cell  ( 286) 1201 222.7 1.1e-57
XP_011513657 (OMIM: 147625) PREDICTED: islet cell  ( 303) 1201 222.7 1.1e-57
XP_011513658 (OMIM: 147625) PREDICTED: islet cell  ( 303) 1201 222.7 1.1e-57


>>NP_001263407 (OMIM: 147625) islet cell autoantigen 1 i  (482 aa)
 initn: 3204 init1: 3204 opt: 3204  Z-score: 3062.6  bits: 576.1 E(85289): 7.6e-164
Smith-Waterman score: 3204; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)

               10        20        30        40        50        60
pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
              430       440       450       460       470       480

         
pF1KB8 NA
       ::
NP_001 NA
         

>>XP_016867610 (OMIM: 147625) PREDICTED: islet cell auto  (482 aa)
 initn: 3204 init1: 3204 opt: 3204  Z-score: 3062.6  bits: 576.1 E(85289): 7.6e-164
Smith-Waterman score: 3204; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)

               10        20        30        40        50        60
pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
              430       440       450       460       470       480

         
pF1KB8 NA
       ::
XP_016 NA
         

>>XP_016867609 (OMIM: 147625) PREDICTED: islet cell auto  (482 aa)
 initn: 3204 init1: 3204 opt: 3204  Z-score: 3062.6  bits: 576.1 E(85289): 7.6e-164
Smith-Waterman score: 3204; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)

               10        20        30        40        50        60
pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
              430       440       450       460       470       480

         
pF1KB8 NA
       ::
XP_016 NA
         

>>XP_016867608 (OMIM: 147625) PREDICTED: islet cell auto  (482 aa)
 initn: 3204 init1: 3204 opt: 3204  Z-score: 3062.6  bits: 576.1 E(85289): 7.6e-164
Smith-Waterman score: 3204; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)

               10        20        30        40        50        60
pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
              430       440       450       460       470       480

         
pF1KB8 NA
       ::
XP_016 NA
         

>>XP_005249792 (OMIM: 147625) PREDICTED: islet cell auto  (482 aa)
 initn: 3204 init1: 3204 opt: 3204  Z-score: 3062.6  bits: 576.1 E(85289): 7.6e-164
Smith-Waterman score: 3204; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)

               10        20        30        40        50        60
pF1KB8 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQT
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELL
              430       440       450       460       470       480

         
pF1KB8 NA
       ::
XP_005 NA
         

>>NP_004959 (OMIM: 147625) islet cell autoantigen 1 isof  (483 aa)
 initn: 3190 init1: 3155 opt: 3192  Z-score: 3051.1  bits: 574.0 E(85289): 3.3e-163
Smith-Waterman score: 3192; 99.8% identity (99.8% similar) in 483 aa overlap (1-482:1-483)

                10        20        30        40        50         
pF1KB8 MSGHKC-YPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB8 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB8 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB8 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB8 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB8 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
              430       440       450       460       470       480

     480  
pF1KB8 LNA
       :::
NP_004 LNA
          

>>XP_016867606 (OMIM: 147625) PREDICTED: islet cell auto  (483 aa)
 initn: 3190 init1: 3155 opt: 3192  Z-score: 3051.1  bits: 574.0 E(85289): 3.3e-163
Smith-Waterman score: 3192; 99.8% identity (99.8% similar) in 483 aa overlap (1-482:1-483)

                10        20        30        40        50         
pF1KB8 MSGHKC-YPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB8 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB8 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB8 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB8 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB8 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
              430       440       450       460       470       480

     480  
pF1KB8 LNA
       :::
XP_016 LNA
          

>>NP_001129492 (OMIM: 147625) islet cell autoantigen 1 i  (483 aa)
 initn: 3190 init1: 3155 opt: 3192  Z-score: 3051.1  bits: 574.0 E(85289): 3.3e-163
Smith-Waterman score: 3192; 99.8% identity (99.8% similar) in 483 aa overlap (1-482:1-483)

                10        20        30        40        50         
pF1KB8 MSGHKC-YPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB8 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB8 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB8 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB8 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB8 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
              430       440       450       460       470       480

     480  
pF1KB8 LNA
       :::
NP_001 LNA
          

>>XP_016867607 (OMIM: 147625) PREDICTED: islet cell auto  (483 aa)
 initn: 3190 init1: 3155 opt: 3192  Z-score: 3051.1  bits: 574.0 E(85289): 3.3e-163
Smith-Waterman score: 3192; 99.8% identity (99.8% similar) in 483 aa overlap (1-482:1-483)

                10        20        30        40        50         
pF1KB8 MSGHKC-YPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB8 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB8 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB8 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB8 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB8 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
              430       440       450       460       470       480

     480  
pF1KB8 LNA
       :::
XP_016 LNA
          

>>NP_071682 (OMIM: 147625) islet cell autoantigen 1 isof  (483 aa)
 initn: 3190 init1: 3155 opt: 3192  Z-score: 3051.1  bits: 574.0 E(85289): 3.3e-163
Smith-Waterman score: 3192; 99.8% identity (99.8% similar) in 483 aa overlap (1-482:1-483)

                10        20        30        40        50         
pF1KB8 MSGHKC-YPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MSGHKCSYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKAL
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 CFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQEL
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB8 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLH
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB8 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPS
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KB8 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVA
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KB8 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQ
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KB8 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 TGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHEL
              430       440       450       460       470       480

     480  
pF1KB8 LNA
       :::
NP_071 LNA
          




482 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 21:34:30 2016 done: Sat Nov  5 21:34:31 2016
 Total Scan time:  8.530 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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