Result of FASTA (omim) for pF1KB6657
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6657, 423 aa
  1>>>pF1KB6657 423 - 423 aa - 423 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4012+/-0.000524; mu= 11.8864+/- 0.032
 mean_var=181.6642+/-42.906, 0's: 0 Z-trim(112.0): 322  B-trim: 322 in 1/52
 Lambda= 0.095157
 statistics sampled from 20280 (20738) to 20280 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.243), width:  16
 Scan time:  8.290

The best scores are:                                      opt bits E(85289)
NP_060726 (OMIM: 616620) ribosome biogenesis prote ( 423) 2855 405.3 1.5e-112
XP_011509771 (OMIM: 616620) PREDICTED: ribosome bi ( 285) 1851 267.3 3.6e-71
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334)  284 52.2 2.3e-06
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334)  284 52.2 2.3e-06
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334)  284 52.2 2.3e-06
NP_006089 (OMIM: 176981) receptor of activated pro ( 317)  270 50.3 8.4e-06
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540)  270 50.6 1.2e-05
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589)  270 50.6 1.2e-05
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627)  270 50.7 1.3e-05
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  270 50.7 1.3e-05
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679)  270 50.7 1.3e-05
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  270 50.7 1.4e-05
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  270 50.7 1.4e-05
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  270 50.7 1.4e-05
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707)  270 50.7 1.4e-05
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707)  270 50.7 1.4e-05
NP_001128728 (OMIM: 602923) histone-binding protei ( 390)  265 49.7 1.5e-05
NP_001128727 (OMIM: 602923) histone-binding protei ( 424)  265 49.8 1.6e-05
NP_005601 (OMIM: 602923) histone-binding protein R ( 425)  265 49.8 1.6e-05
XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 ( 246)  261 48.9 1.7e-05
XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 ( 246)  261 48.9 1.7e-05
XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 ( 246)  261 48.9 1.7e-05
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300)  261 49.0 1.9e-05
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326)  261 49.1   2e-05
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359)  261 49.1 2.1e-05
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374)  261 49.1 2.2e-05
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407)  261 49.2 2.3e-05
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279)  251 47.6 4.7e-05
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279)  251 47.6 4.7e-05
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410)  234 45.5  0.0003
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410)  234 45.5  0.0003
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410)  234 45.5  0.0003
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410)  234 45.5  0.0003
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428)  234 45.5 0.00031
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428)  234 45.5 0.00031
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428)  234 45.5 0.00031
NP_002884 (OMIM: 300825) histone-binding protein R ( 425)  232 45.2 0.00037
NP_001185648 (OMIM: 300825) histone-binding protei ( 469)  232 45.3  0.0004
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345)  229 44.7 0.00044
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655)  232 45.5 0.00048
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655)  232 45.5 0.00048
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655)  232 45.5 0.00048
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658)  232 45.5 0.00049
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672)  232 45.5 0.00049
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672)  232 45.5 0.00049
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672)  232 45.5 0.00049
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675)  232 45.5 0.00049
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675)  232 45.5 0.00049
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675)  232 45.5 0.00049
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675)  232 45.5 0.00049


>>NP_060726 (OMIM: 616620) ribosome biogenesis protein W  (423 aa)
 initn: 2855 init1: 2855 opt: 2855  Z-score: 2141.7  bits: 405.3 E(85289): 1.5e-112
Smith-Waterman score: 2855; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423)

               10        20        30        40        50        60
pF1KB6 MAQLQTRFYTDNKKYAVDDVPFSIPAASEIADLSNIINKLLKDKNEFHKHVEFDFLIKGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MAQLQTRFYTDNKKYAVDDVPFSIPAASEIADLSNIINKLLKDKNEFHKHVEFDFLIKGQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 FLRMPLDKHMEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FLRMPLDKHMEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 KTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 ALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 EQLGLTRTPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EQLGLTRTPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 NCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLIS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 GSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSH
              370       380       390       400       410       420

          
pF1KB6 VGA
       :::
NP_060 VGA
          

>>XP_011509771 (OMIM: 616620) PREDICTED: ribosome biogen  (285 aa)
 initn: 1851 init1: 1851 opt: 1851  Z-score: 1398.7  bits: 267.3 E(85289): 3.6e-71
Smith-Waterman score: 1851; 99.3% identity (100.0% similar) in 274 aa overlap (150-423:12-285)

     120       130       140       150       160       170         
pF1KB6 DKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKV
                                     ..::::::::::::::::::::::::::::
XP_011                    MMTGSVQLKGQRNDSLSCLLLSASMDQTILLWEWNVERNKV
                                  10        20        30        40 

     180       190       200       210       220       230         
pF1KB6 KALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQK
              50        60        70        80        90       100 

     240       250       260       270       280       290         
pF1KB6 TEQLGLTRTPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEQLGLTRTPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKV
             110       120       130       140       150       160 

     300       310       320       330       340       350         
pF1KB6 FNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLI
             170       180       190       200       210       220 

     360       370       380       390       400       410         
pF1KB6 SGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTS
             230       240       250       260       270       280 

     420   
pF1KB6 HVGA
       ::::
XP_011 HVGA
           

>>NP_060058 (OMIM: 609012) WD repeat-containing protein   (334 aa)
 initn: 216 init1:  98 opt: 284  Z-score: 235.3  bits: 52.2 E(85289): 2.3e-06
Smith-Waterman score: 330; 29.2% identity (55.6% similar) in 277 aa overlap (100-370:44-286)

      70        80        90       100       110         120       
pF1KB6 MEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAE--EWILTGSYDKTSRIW-
                                     :   .::.: .   ::. ..: ::  .:: 
NP_060 RAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG
            20        30        40        50        60        70   

        130       140       150       160       170       180      
pF1KB6 SLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCR
       . .::   :: ::   ..::::   .: : ::.::: :.:. .:    . .. : :.  .
NP_060 AYDGKFEKTISGHKLGISDVAW---SSDSNLLVSASDDKTLKIW----DVSSGKCLKTLK
            80        90          100       110           120      

        190       200       210       220       230       240      
pF1KB6 GHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLT
       ::.. :     . ... . :::.:. ..::..           .:..  :          
NP_060 GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV-----------KTGKCLK----------
        130       140       150                  160               

        250       260        270       280       290         300   
pF1KB6 RTPIVTLSGHMEAVSSVLWS-DAEEICSASWDHTIRVWDVESGSLKSTLTG--NKVFNCI
            :: .: . ::.: .. :.  : :.:.:   :.::. ::.  .::    :   . .
NP_060 -----TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV
              170       180       190       200       210       220

           310       320       330       340       350       360   
pF1KB6 SYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSL
       ..::  : . ... :  ..:::  .:   : . .  ..  .   ...: :  . ..::: 
NP_060 KFSPNGKYILAATLDNTLKLWD-YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE
              230       240        250       260       270         

           370       380       390       400       410       420   
pF1KB6 DNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA
       ::.: .:                                                     
NP_060 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC     
     280       290       300       310       320       330         

>>NP_438172 (OMIM: 609012) WD repeat-containing protein   (334 aa)
 initn: 216 init1:  98 opt: 284  Z-score: 235.3  bits: 52.2 E(85289): 2.3e-06
Smith-Waterman score: 330; 29.2% identity (55.6% similar) in 277 aa overlap (100-370:44-286)

      70        80        90       100       110         120       
pF1KB6 MEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAE--EWILTGSYDKTSRIW-
                                     :   .::.: .   ::. ..: ::  .:: 
NP_438 RAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG
            20        30        40        50        60        70   

        130       140       150       160       170       180      
pF1KB6 SLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCR
       . .::   :: ::   ..::::   .: : ::.::: :.:. .:    . .. : :.  .
NP_438 AYDGKFEKTISGHKLGISDVAW---SSDSNLLVSASDDKTLKIW----DVSSGKCLKTLK
            80        90          100       110           120      

        190       200       210       220       230       240      
pF1KB6 GHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLT
       ::.. :     . ... . :::.:. ..::..           .:..  :          
NP_438 GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV-----------KTGKCLK----------
        130       140       150                  160               

        250       260        270       280       290         300   
pF1KB6 RTPIVTLSGHMEAVSSVLWS-DAEEICSASWDHTIRVWDVESGSLKSTLTG--NKVFNCI
            :: .: . ::.: .. :.  : :.:.:   :.::. ::.  .::    :   . .
NP_438 -----TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV
              170       180       190       200       210       220

           310       320       330       340       350       360   
pF1KB6 SYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSL
       ..::  : . ... :  ..:::  .:   : . .  ..  .   ...: :  . ..::: 
NP_438 KFSPNGKYILAATLDNTLKLWD-YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE
              230       240        250       260       270         

           370       380       390       400       410       420   
pF1KB6 DNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA
       ::.: .:                                                     
NP_438 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC     
     280       290       300       310       320       330         

>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta  (334 aa)
 initn: 216 init1:  98 opt: 284  Z-score: 235.3  bits: 52.2 E(85289): 2.3e-06
Smith-Waterman score: 330; 29.2% identity (55.6% similar) in 277 aa overlap (100-370:44-286)

      70        80        90       100       110         120       
pF1KB6 MEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAE--EWILTGSYDKTSRIW-
                                     :   .::.: .   ::. ..: ::  .:: 
XP_005 RAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG
            20        30        40        50        60        70   

        130       140       150       160       170       180      
pF1KB6 SLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCR
       . .::   :: ::   ..::::   .: : ::.::: :.:. .:    . .. : :.  .
XP_005 AYDGKFEKTISGHKLGISDVAW---SSDSNLLVSASDDKTLKIW----DVSSGKCLKTLK
            80        90          100       110           120      

        190       200       210       220       230       240      
pF1KB6 GHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLT
       ::.. :     . ... . :::.:. ..::..           .:..  :          
XP_005 GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV-----------KTGKCLK----------
        130       140       150                  160               

        250       260        270       280       290         300   
pF1KB6 RTPIVTLSGHMEAVSSVLWS-DAEEICSASWDHTIRVWDVESGSLKSTLTG--NKVFNCI
            :: .: . ::.: .. :.  : :.:.:   :.::. ::.  .::    :   . .
XP_005 -----TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV
              170       180       190       200       210       220

           310       320       330       340       350       360   
pF1KB6 SYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSL
       ..::  : . ... :  ..:::  .:   : . .  ..  .   ...: :  . ..::: 
XP_005 KFSPNGKYILAATLDNTLKLWD-YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE
              230       240        250       260       270         

           370       380       390       400       410       420   
pF1KB6 DNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA
       ::.: .:                                                     
XP_005 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC     
     280       290       300       310       320       330         

>>NP_006089 (OMIM: 176981) receptor of activated protein  (317 aa)
 initn: 148 init1:  99 opt: 270  Z-score: 225.2  bits: 50.3 E(85289): 8.4e-06
Smith-Waterman score: 274; 29.8% identity (56.1% similar) in 228 aa overlap (186-408:12-215)

         160       170       180       190       200        210    
pF1KB6 CLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGS-GTKFCSGSWDKMLK
                                     .:: : : .::.  .    . :.: :: . 
NP_006                    MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTII
                                  10        20        30        40 

          220       230       240       250       260        270   
pF1KB6 IWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWS-DAEEICS
       .:. .    .::    ::           :.   :  .: :: . ::.:. : :..   :
NP_006 MWKLT----RDE----TNY----------GI---PQRALRGHSHFVSDVVISSDGQFALS
                      50                     60        70        80

           280       290        300       310       320       330  
pF1KB6 ASWDHTIRVWDVESGSLKSTLTGN-KVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGS
       .::: :.:.::. .:.    ..:. :    ...:   ....::: :. :.::.  :    
NP_006 GSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN--TLGVC
               90       100       110       120       130          

            340       350        360       370       380       390 
pF1KB6 LVSLSLTSHTGWVTSVKWSPTHEQQLI-SGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLS
         ...  ::. ::. :..::.  . .: : . :..::.:.  .::     .. :   . .
NP_006 KYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG-HTGYLNT
      140       150       160       170       180       190        

              400       410       420                              
pF1KB6 VDWTDTG-LLLSGGADNKLYSYRYSPTTSHVGA                           
       :  .  : :  ::: :..                                          
NP_006 VTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIK
       200       210       220       230       240       250       

>>XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD repeat  (540 aa)
 initn: 273 init1:  82 opt: 270  Z-score: 222.6  bits: 50.6 E(85289): 1.2e-05
Smith-Waterman score: 334; 30.3% identity (57.3% similar) in 274 aa overlap (103-374:258-486)

             80        90       100       110       120        130 
pF1KB6 ENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYDKTSRIWSLE-GK
                                     : :...  .. :..:: :.: ..:. : :.
XP_011 VSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGE
       230       240       250       260         270       280     

             140       150       160       170       180       190 
pF1KB6 SIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGS
        : :. :::..:. .   .:      ..:.: : :. .:.  .: ..   ::   ::...
XP_011 CIHTLYGHTSTVRCMHLHEKR-----VVSGSRDATLRVWD--IETGQC--LHVLMGHVAA
         290       300            310       320           330      

             200       210       220       230       240       250 
pF1KB6 VDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIV
       :  .  ::   .  ::..: :.:.:     : : :                     : . 
XP_011 VRCVQYDGR--RVVSGAYDFMVKVW-----DPETE---------------------TCLH
        340         350            360                             

             260       270       280       290       300       310 
pF1KB6 TLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKR
       ::.:: . : : :  :. .. :.: : .:::::::.:.   ::::.. ..  :   :   
XP_011 TLQGHTNRVYS-LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT--SGMELKDN
      370        380       390       400       410         420     

              320       330       340       350       360       370
pF1KB6 -LASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW
        :.::..:  ...:: .: .   .  . ..: . :: .... .    .:..: :. ::::
XP_011 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF---VITSSDDGTVKLW
         430       440       450       460          470       480  

              380       390       400       410       420        
pF1KB6 DTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA     
       : ..                                                      
XP_011 DLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
            490       500       510       520       530       540

>>NP_001013433 (OMIM: 606278) F-box/WD repeat-containing  (589 aa)
 initn: 329 init1:  82 opt: 270  Z-score: 222.2  bits: 50.6 E(85289): 1.2e-05
Smith-Waterman score: 334; 30.3% identity (57.3% similar) in 274 aa overlap (103-374:307-535)

             80        90       100       110       120        130 
pF1KB6 ENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYDKTSRIWSLE-GK
                                     : :...  .. :..:: :.: ..:. : :.
NP_001 VSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGE
        280       290       300       310         320       330    

             140       150       160       170       180       190 
pF1KB6 SIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGS
        : :. :::..:. .   .:      ..:.: : :. .:.  .: ..   ::   ::...
NP_001 CIHTLYGHTSTVRCMHLHEKR-----VVSGSRDATLRVWD--IETGQC--LHVLMGHVAA
          340       350            360         370         380     

             200       210       220       230       240       250 
pF1KB6 VDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIV
       :  .  ::   .  ::..: :.:.:     : : :                     : . 
NP_001 VRCVQYDGR--RVVSGAYDFMVKVW-----DPETE---------------------TCLH
         390         400            410                            

             260       270       280       290       300       310 
pF1KB6 TLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKR
       ::.:: . : : :  :. .. :.: : .:::::::.:.   ::::.. ..  :   :   
NP_001 TLQGHTNRVYS-LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT--SGMELKDN
       420        430       440       450       460         470    

              320       330       340       350       360       370
pF1KB6 -LASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW
        :.::..:  ...:: .: .   .  . ..: . :: .... .    .:..: :. ::::
NP_001 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF---VITSSDDGTVKLW
          480       490       500       510          520       530 

              380       390       400       410       420        
pF1KB6 DTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA     
       : ..                                                      
NP_001 DLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
             540       550       560       570       580         

>>NP_060785 (OMIM: 606278) F-box/WD repeat-containing pr  (627 aa)
 initn: 275 init1:  82 opt: 270  Z-score: 221.9  bits: 50.7 E(85289): 1.3e-05
Smith-Waterman score: 334; 30.3% identity (57.3% similar) in 274 aa overlap (103-374:345-573)

             80        90       100       110       120        130 
pF1KB6 ENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYDKTSRIWSLE-GK
                                     : :...  .. :..:: :.: ..:. : :.
NP_060 VSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGE
          320       330       340       350         360       370  

             140       150       160       170       180       190 
pF1KB6 SIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGS
        : :. :::..:. .   .:      ..:.: : :. .:.  .: ..   ::   ::...
NP_060 CIHTLYGHTSTVRCMHLHEKR-----VVSGSRDATLRVWD--IETGQC--LHVLMGHVAA
            380       390            400         410         420   

             200       210       220       230       240       250 
pF1KB6 VDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIV
       :  .  ::   .  ::..: :.:.:     : : :                     : . 
NP_060 VRCVQYDGR--RVVSGAYDFMVKVW-----DPETE---------------------TCLH
           430         440            450                          

             260       270       280       290       300       310 
pF1KB6 TLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKR
       ::.:: . : : :  :. .. :.: : .:::::::.:.   ::::.. ..  :   :   
NP_060 TLQGHTNRVYS-LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT--SGMELKDN
         460        470       480       490       500         510  

              320       330       340       350       360       370
pF1KB6 -LASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW
        :.::..:  ...:: .: .   .  . ..: . :: .... .    .:..: :. ::::
NP_060 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF---VITSSDDGTVKLW
            520       530       540       550          560         

              380       390       400       410       420        
pF1KB6 DTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA     
       : ..                                                      
NP_060 DLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
     570       580       590       600       610       620       

>>XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD repeat  (679 aa)
 initn: 329 init1:  82 opt: 270  Z-score: 221.6  bits: 50.7 E(85289): 1.3e-05
Smith-Waterman score: 334; 30.3% identity (57.3% similar) in 274 aa overlap (103-374:397-625)

             80        90       100       110       120        130 
pF1KB6 ENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYDKTSRIWSLE-GK
                                     : :...  .. :..:: :.: ..:. : :.
XP_011 VSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGE
        370       380       390       400         410       420    

             140       150       160       170       180       190 
pF1KB6 SIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGS
        : :. :::..:. .   .:      ..:.: : :. .:.  .: ..   ::   ::...
XP_011 CIHTLYGHTSTVRCMHLHEKR-----VVSGSRDATLRVWD--IETGQC--LHVLMGHVAA
          430       440            450         460         470     

             200       210       220       230       240       250 
pF1KB6 VDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIV
       :  .  ::   .  ::..: :.:.:     : : :                     : . 
XP_011 VRCVQYDGR--RVVSGAYDFMVKVW-----DPETE---------------------TCLH
         480         490            500                            

             260       270       280       290       300       310 
pF1KB6 TLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKR
       ::.:: . : : :  :. .. :.: : .:::::::.:.   ::::.. ..  :   :   
XP_011 TLQGHTNRVYS-LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT--SGMELKDN
       510        520       530       540       550         560    

              320       330       340       350       360       370
pF1KB6 -LASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW
        :.::..:  ...:: .: .   .  . ..: . :: .... .    .:..: :. ::::
XP_011 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF---VITSSDDGTVKLW
          570       580       590       600          610       620 

              380       390       400       410       420        
pF1KB6 DTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA     
       : ..                                                      
XP_011 DLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
             630       640       650       660       670         




423 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 11:17:12 2016 done: Sat Nov  5 11:17:13 2016
 Total Scan time:  8.290 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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