Result of FASTA (omim) for pF1KB6176
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6176, 606 aa
  1>>>pF1KB6176 606 - 606 aa - 606 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.9828+/-0.000486; mu= 5.8857+/- 0.030
 mean_var=693.1709+/-160.168, 0's: 0 Z-trim(119.8): 1271  B-trim: 0 in 0/57
 Lambda= 0.048714
 statistics sampled from 32441 (34328) to 32441 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.402), width:  16
 Scan time: 11.050

The best scores are:                                      opt bits E(85289)
XP_011542210 (OMIM: 311010) PREDICTED: serine/thre ( 606) 4125 306.1 2.3e-82
NP_001645 (OMIM: 311010) serine/threonine-protein  ( 606) 4125 306.1 2.3e-82
NP_001243125 (OMIM: 311010) serine/threonine-prote ( 609) 4109 305.0   5e-82
XP_006724592 (OMIM: 311010) PREDICTED: serine/thre ( 611) 4105 304.7 6.1e-82
XP_011542208 (OMIM: 311010) PREDICTED: serine/thre ( 611) 4105 304.7 6.1e-82
XP_011542211 (OMIM: 311010) PREDICTED: serine/thre ( 387) 2586 197.6 6.8e-50
XP_005265412 (OMIM: 164760,611553,611554,615916) P ( 648) 2457 188.9 4.6e-47
NP_002871 (OMIM: 164760,611553,611554,615916) RAF  ( 648) 2457 188.9 4.6e-47
XP_011532276 (OMIM: 164760,611553,611554,615916) P ( 648) 2457 188.9 4.6e-47
XP_005265415 (OMIM: 164760,611553,611554,615916) P ( 567) 2221 172.2 4.2e-42
XP_011532277 (OMIM: 164760,611553,611554,615916) P ( 567) 2221 172.2 4.2e-42
XP_005265416 (OMIM: 164760,611553,611554,615916) P ( 534) 1825 144.3 9.8e-34
XP_005265414 (OMIM: 164760,611553,611554,615916) P ( 615) 1825 144.4   1e-33
XP_016862455 (OMIM: 164760,611553,611554,615916) P ( 615) 1825 144.4   1e-33
NP_004324 (OMIM: 115150,163950,164757,211980,61370 ( 766) 1781 141.5 9.8e-33
XP_005250102 (OMIM: 115150,163950,164757,211980,61 ( 767) 1781 141.5 9.8e-33
XP_016868047 (OMIM: 115150,163950,164757,211980,61 ( 807) 1672 133.9   2e-30
XP_016868048 (OMIM: 115150,163950,164757,211980,61 ( 798) 1538 124.5 1.4e-27
NP_001243126 (OMIM: 311010) serine/threonine-prote ( 186) 1287 105.7 1.5e-22
XP_006722217 (OMIM: 601132) PREDICTED: kinase supp ( 887)  557 55.6 8.2e-07
XP_016874699 (OMIM: 610737) PREDICTED: kinase supp ( 515)  547 54.5 1.1e-06
XP_011536530 (OMIM: 610737) PREDICTED: kinase supp ( 647)  547 54.7 1.2e-06
XP_011536527 (OMIM: 610737) PREDICTED: kinase supp ( 829)  547 54.9 1.3e-06
XP_016880757 (OMIM: 601132) PREDICTED: kinase supp ( 901)  547 54.9 1.3e-06
NP_775869 (OMIM: 610737) kinase suppressor of Ras  ( 921)  547 55.0 1.4e-06
XP_011536526 (OMIM: 610737) PREDICTED: kinase supp ( 948)  547 55.0 1.4e-06
XP_016880758 (OMIM: 601132) PREDICTED: kinase supp ( 876)  540 54.4 1.9e-06
XP_016880756 (OMIM: 601132) PREDICTED: kinase supp ( 909)  531 53.8   3e-06
XP_016880767 (OMIM: 601132) PREDICTED: kinase supp ( 587)  514 52.3 5.6e-06
XP_016880766 (OMIM: 601132) PREDICTED: kinase supp ( 605)  514 52.3 5.7e-06
XP_016866141 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537)  511 52.0 6.2e-06
XP_016866143 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537)  511 52.0 6.2e-06
XP_016866140 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537)  511 52.0 6.2e-06
NP_002028 (OMIM: 137025) tyrosine-protein kinase F ( 537)  511 52.0 6.2e-06
XP_016866139 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537)  511 52.0 6.2e-06
XP_016866142 (OMIM: 137025) PREDICTED: tyrosine-pr ( 537)  511 52.0 6.2e-06
XP_016880760 (OMIM: 601132) PREDICTED: kinase supp ( 786)  514 52.5 6.3e-06
XP_016880762 (OMIM: 601132) PREDICTED: kinase supp ( 786)  514 52.5 6.3e-06
XP_016880765 (OMIM: 601132) PREDICTED: kinase supp ( 786)  514 52.5 6.3e-06
XP_016880763 (OMIM: 601132) PREDICTED: kinase supp ( 786)  514 52.5 6.3e-06
XP_016880761 (OMIM: 601132) PREDICTED: kinase supp ( 786)  514 52.5 6.3e-06
XP_016880764 (OMIM: 601132) PREDICTED: kinase supp ( 786)  514 52.5 6.3e-06
XP_016880759 (OMIM: 601132) PREDICTED: kinase supp ( 804)  514 52.5 6.4e-06
XP_011523731 (OMIM: 601132) PREDICTED: kinase supp ( 923)  514 52.6 6.8e-06
NP_055053 (OMIM: 601132) kinase suppressor of Ras  ( 762)  511 52.3 7.2e-06
XP_011523732 (OMIM: 601132) PREDICTED: kinase supp ( 899)  511 52.4 7.8e-06
XP_011523733 (OMIM: 601132) PREDICTED: kinase supp ( 898)  507 52.1 9.5e-06
XP_011533958 (OMIM: 606573) PREDICTED: tyrosine-pr ( 392)  498 50.8   1e-05
XP_016866134 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505)  498 51.0 1.1e-05
NP_002022 (OMIM: 606573) tyrosine-protein kinase F ( 505)  498 51.0 1.1e-05


>>XP_011542210 (OMIM: 311010) PREDICTED: serine/threonin  (606 aa)
 initn: 4125 init1: 4125 opt: 4125  Z-score: 1599.8  bits: 306.1 E(85289): 2.3e-82
Smith-Waterman score: 4125; 100.0% identity (100.0% similar) in 606 aa overlap (1-606:1-606)

               10        20        30        40        50        60
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 TPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 TDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 YYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 TRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 HAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 QDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 AMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLS
              550       560       570       580       590       600

             
pF1KB6 AARLVP
       ::::::
XP_011 AARLVP
             

>>NP_001645 (OMIM: 311010) serine/threonine-protein kina  (606 aa)
 initn: 4125 init1: 4125 opt: 4125  Z-score: 1599.8  bits: 306.1 E(85289): 2.3e-82
Smith-Waterman score: 4125; 100.0% identity (100.0% similar) in 606 aa overlap (1-606:1-606)

               10        20        30        40        50        60
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 TPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 TDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 YYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 TRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 HAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRM
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 QDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 AMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLS
              550       560       570       580       590       600

             
pF1KB6 AARLVP
       ::::::
NP_001 AARLVP
             

>>NP_001243125 (OMIM: 311010) serine/threonine-protein k  (609 aa)
 initn: 3063 init1: 3063 opt: 4109  Z-score: 1593.7  bits: 305.0 E(85289): 5e-82
Smith-Waterman score: 4109; 99.5% identity (99.5% similar) in 609 aa overlap (1-606:1-609)

               10        20        30        40        50        60
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
               70        80        90       100       110       120

              130       140       150          160       170       
pF1KB6 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQ---FYHSVQDLSGGSRQHEAPSNRPLN
       :::::::::::::::::::::::::::::::::   ::::::::::::::::::::::::
NP_001 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQPSRFYHSVQDLSGGSRQHEAPSNRPLN
              130       140       150       160       170       180

       180       190       200       210       220       230       
pF1KB6 ELLTPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLTPQGPSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQ
              190       200       210       220       230       240

       240       250       260       270       280       290       
pF1KB6 SFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYR
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KB6 DSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQV
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KB6 LRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGM
              370       380       390       400       410       420

       420       430       440       450       460       470       
pF1KB6 DYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEV
              430       440       450       460       470       480

       480       490       500       510       520       530       
pF1KB6 IRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSN
              490       500       510       520       530       540

       540       550       560       570       580       590       
pF1KB6 CPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPAC
              550       560       570       580       590       600

       600      
pF1KB6 LLSAARLVP
       :::::::::
NP_001 LLSAARLVP
                

>>XP_006724592 (OMIM: 311010) PREDICTED: serine/threonin  (611 aa)
 initn: 2838 init1: 2838 opt: 4105  Z-score: 1592.1  bits: 304.7 E(85289): 6.1e-82
Smith-Waterman score: 4105; 99.2% identity (99.2% similar) in 611 aa overlap (1-606:1-611)

               10        20        30        40        50        60
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
              130       140       150       160       170       180

                   190       200       210       220       230     
pF1KB6 TPQGPS-----PRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLT
       ::::::     :::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPQGPSLSPGSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLT
              190       200       210       220       230       240

         240       250       260       270       280       290     
pF1KB6 GQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLG
              250       260       270       280       290       300

         300       310       320       330       340       350     
pF1KB6 YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEM
              310       320       330       340       350       360

         360       370       380       390       400       410     
pF1KB6 QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
              370       380       390       400       410       420

         420       430       440       450       460       470     
pF1KB6 GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
              430       440       450       460       470       480

         480       490       500       510       520       530     
pF1KB6 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKIS
              490       500       510       520       530       540

         540       550       560       570       580       590     
pF1KB6 SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
              550       560       570       580       590       600

         600      
pF1KB6 ACLLSAARLVP
       :::::::::::
XP_006 ACLLSAARLVP
              610 

>>XP_011542208 (OMIM: 311010) PREDICTED: serine/threonin  (611 aa)
 initn: 2838 init1: 2838 opt: 4105  Z-score: 1592.1  bits: 304.7 E(85289): 6.1e-82
Smith-Waterman score: 4105; 99.2% identity (99.2% similar) in 611 aa overlap (1-606:1-611)

               10        20        30        40        50        60
pF1KB6 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQDLSGGSRQHEAPSNRPLNELL
              130       140       150       160       170       180

                   190       200       210       220       230     
pF1KB6 TPQGPS-----PRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLT
       ::::::     :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPQGPSLSPGSPRTQHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLT
              190       200       210       220       230       240

         240       250       260       270       280       290     
pF1KB6 GQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQSFSTDAAGSRGGSDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLG
              250       260       270       280       290       300

         300       310       320       330       340       350     
pF1KB6 YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEM
              310       320       330       340       350       360

         360       370       380       390       400       410     
pF1KB6 QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
              370       380       390       400       410       420

         420       430       440       450       460       470     
pF1KB6 GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
              430       440       450       460       470       480

         480       490       500       510       520       530     
pF1KB6 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKIS
              490       500       510       520       530       540

         540       550       560       570       580       590     
pF1KB6 SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
              550       560       570       580       590       600

         600      
pF1KB6 ACLLSAARLVP
       :::::::::::
XP_011 ACLLSAARLVP
              610 

>>XP_011542211 (OMIM: 311010) PREDICTED: serine/threonin  (387 aa)
 initn: 2586 init1: 2586 opt: 2586  Z-score: 1016.8  bits: 197.6 E(85289): 6.8e-50
Smith-Waterman score: 2586; 100.0% identity (100.0% similar) in 387 aa overlap (220-606:1-387)

     190       200       210       220       230       240         
pF1KB6 QHCDPEHFPFPAPANAPLQRIRSTSTPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGG
                                     ::::::::::::::::::::::::::::::
XP_011                               MVSTTAPMDSNLIQLTGQSFSTDAAGSRGG
                                             10        20        30

     250       260       270       280       290       300         
pF1KB6 SDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDGTPRGSPSPASVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLGYRDSGYYWEVPPSE
               40        50        60        70        80        90

     310       320       330       340       350       360         
pF1KB6 VQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLF
              100       110       120       130       140       150

     370       380       390       400       410       420         
pF1KB6 MGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRD
              160       170       180       190       200       210

     430       440       450       460       470       480         
pF1KB6 LKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQ
              220       230       240       250       260       270

     490       500       510       520       530       540         
pF1KB6 SDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDC
              280       290       300       310       320       330

     550       560       570       580       590       600      
pF1KB6 LKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP
              340       350       360       370       380       

>>XP_005265412 (OMIM: 164760,611553,611554,615916) PREDI  (648 aa)
 initn: 2208 init1: 1617 opt: 2457  Z-score: 966.0  bits: 188.9 E(85289): 4.6e-47
Smith-Waterman score: 2457; 61.9% identity (81.1% similar) in 607 aa overlap (13-606:50-646)

                                 10        20        30        40  
pF1KB6                   MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVY
                                     .::.. .:..:.:::::::::.::.:::..
XP_005 AVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLH
      20        30        40        50        60        70         

             50        60           70        80        90         
pF1KB6 DSLDKALKVRGLNQDCCVVYRLI---KGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMH
       : : ::::::::. .::.:.::.   ::.:.   :.:  : : :::: :. :. :::: :
XP_005 DCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTH
      80        90       100       110       120       130         

     100       110       120       130       140       150         
pF1KB6 NFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQ
       ::.::::..:::::.: :::..::::::::::::.:::.::::.::: :. :: .    .
XP_005 NFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNS
     140       150       160       170       180       190         

     160       170         180       190           200       210   
pF1KB6 DLSGGSRQHEAPS--NRPLNELLTPQGPSPRTQHCDPEHFPF----PAPANAPLQRIRST
        . : :     ::   : . : .. .  : . ..  :. : :    :.  ..  :: :::
XP_005 TI-GDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRST
     200        210       220       230       240       250        

           220       230       240       250       260        270  
pF1KB6 STPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVS-SGRKSPHS
       ::::::::::: :.:: .:.        ::  :.. : .    : :: ..: .: ..:..
XP_005 STPNVHMVSTTLPVDSRMIE--------DAIRSHSESASPSALSSSPNNLSPTGWSQPKT
      260       270               280       290       300       310

            280         290       300       310       320       330
pF1KB6 KSPAEQRERKSLA--DDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWH
         :: ::::  ..  ..:.:..  : :::.::::.  :::.:  :::.::::::..:.::
XP_005 PVPA-QRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWH
               320       330       340       350       360         

              340       350       360       370       380       390
pF1KB6 GDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSL
       ::::::.::: .:: :: :::.::. :::::::::::::::.::. ..::.:::::::::
XP_005 GDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSL
     370       380       390       400       410       420         

              400       410       420       430       440       450
pF1KB6 YHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGL
       :.:::: .:.:.: ::::.::::::::::::::::::::.::::::::::::::::::::
XP_005 YKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGL
     430       440       450       460       470       480         

              460       470       480       490       500       510
pF1KB6 ATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYS
       ::::.::::.: .:::.::::::: ::::::: ::.:::::::.::.:::::::: ::::
XP_005 ATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYS
     490       500       510       520       530       540         

              520       530       540       550       560       570
pF1KB6 HIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELL
       ::. :::::::::::: ::::::. .::::::.::..::.:  .::::::::::..::::
XP_005 HINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELL
     550       560       570       580       590       600         

              580        590       600        
pF1KB6 QRSLPKIERSASEPSLHRT-QADELPACLLSAARLVP  
       :.:::::.::::::::::. ..... :: :...  .:  
XP_005 QHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
     610       620       630       640        

>>NP_002871 (OMIM: 164760,611553,611554,615916) RAF prot  (648 aa)
 initn: 2208 init1: 1617 opt: 2457  Z-score: 966.0  bits: 188.9 E(85289): 4.6e-47
Smith-Waterman score: 2457; 61.9% identity (81.1% similar) in 607 aa overlap (13-606:50-646)

                                 10        20        30        40  
pF1KB6                   MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVY
                                     .::.. .:..:.:::::::::.::.:::..
NP_002 AVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLH
      20        30        40        50        60        70         

             50        60           70        80        90         
pF1KB6 DSLDKALKVRGLNQDCCVVYRLI---KGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMH
       : : ::::::::. .::.:.::.   ::.:.   :.:  : : :::: :. :. :::: :
NP_002 DCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTH
      80        90       100       110       120       130         

     100       110       120       130       140       150         
pF1KB6 NFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQ
       ::.::::..:::::.: :::..::::::::::::.:::.::::.::: :. :: .    .
NP_002 NFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNS
     140       150       160       170       180       190         

     160       170         180       190           200       210   
pF1KB6 DLSGGSRQHEAPS--NRPLNELLTPQGPSPRTQHCDPEHFPF----PAPANAPLQRIRST
        . : :     ::   : . : .. .  : . ..  :. : :    :.  ..  :: :::
NP_002 TI-GDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRST
     200        210       220       230       240       250        

           220       230       240       250       260        270  
pF1KB6 STPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVS-SGRKSPHS
       ::::::::::: :.:: .:.        ::  :.. : .    : :: ..: .: ..:..
NP_002 STPNVHMVSTTLPVDSRMIE--------DAIRSHSESASPSALSSSPNNLSPTGWSQPKT
      260       270               280       290       300       310

            280         290       300       310       320       330
pF1KB6 KSPAEQRERKSLA--DDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWH
         :: ::::  ..  ..:.:..  : :::.::::.  :::.:  :::.::::::..:.::
NP_002 PVPA-QRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWH
               320       330       340       350       360         

              340       350       360       370       380       390
pF1KB6 GDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSL
       ::::::.::: .:: :: :::.::. :::::::::::::::.::. ..::.:::::::::
NP_002 GDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSL
     370       380       390       400       410       420         

              400       410       420       430       440       450
pF1KB6 YHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGL
       :.:::: .:.:.: ::::.::::::::::::::::::::.::::::::::::::::::::
NP_002 YKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGL
     430       440       450       460       470       480         

              460       470       480       490       500       510
pF1KB6 ATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYS
       ::::.::::.: .:::.::::::: ::::::: ::.:::::::.::.:::::::: ::::
NP_002 ATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYS
     490       500       510       520       530       540         

              520       530       540       550       560       570
pF1KB6 HIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELL
       ::. :::::::::::: ::::::. .::::::.::..::.:  .::::::::::..::::
NP_002 HINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELL
     550       560       570       580       590       600         

              580        590       600        
pF1KB6 QRSLPKIERSASEPSLHRT-QADELPACLLSAARLVP  
       :.:::::.::::::::::. ..... :: :...  .:  
NP_002 QHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
     610       620       630       640        

>>XP_011532276 (OMIM: 164760,611553,611554,615916) PREDI  (648 aa)
 initn: 2208 init1: 1617 opt: 2457  Z-score: 966.0  bits: 188.9 E(85289): 4.6e-47
Smith-Waterman score: 2457; 61.9% identity (81.1% similar) in 607 aa overlap (13-606:50-646)

                                 10        20        30        40  
pF1KB6                   MEPPRGPPANGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVY
                                     .::.. .:..:.:::::::::.::.:::..
XP_011 AVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLH
      20        30        40        50        60        70         

             50        60           70        80        90         
pF1KB6 DSLDKALKVRGLNQDCCVVYRLI---KGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMH
       : : ::::::::. .::.:.::.   ::.:.   :.:  : : :::: :. :. :::: :
XP_011 DCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTH
      80        90       100       110       120       130         

     100       110       120       130       140       150         
pF1KB6 NFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHSVQ
       ::.::::..:::::.: :::..::::::::::::.:::.::::.::: :. :: .    .
XP_011 NFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNS
     140       150       160       170       180       190         

     160       170         180       190           200       210   
pF1KB6 DLSGGSRQHEAPS--NRPLNELLTPQGPSPRTQHCDPEHFPF----PAPANAPLQRIRST
        . : :     ::   : . : .. .  : . ..  :. : :    :.  ..  :: :::
XP_011 TI-GDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRST
     200        210       220       230       240       250        

           220       230       240       250       260        270  
pF1KB6 STPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVS-SGRKSPHS
       ::::::::::: :.:: .:.        ::  :.. : .    : :: ..: .: ..:..
XP_011 STPNVHMVSTTLPVDSRMIE--------DAIRSHSESASPSALSSSPNNLSPTGWSQPKT
      260       270               280       290       300       310

            280         290       300       310       320       330
pF1KB6 KSPAEQRERKSLA--DDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWH
         :: ::::  ..  ..:.:..  : :::.::::.  :::.:  :::.::::::..:.::
XP_011 PVPA-QRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWH
               320       330       340       350       360         

              340       350       360       370       380       390
pF1KB6 GDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSL
       ::::::.::: .:: :: :::.::. :::::::::::::::.::. ..::.:::::::::
XP_011 GDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSL
     370       380       390       400       410       420         

              400       410       420       430       440       450
pF1KB6 YHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGL
       :.:::: .:.:.: ::::.::::::::::::::::::::.::::::::::::::::::::
XP_011 YKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGL
     430       440       450       460       470       480         

              460       470       480       490       500       510
pF1KB6 ATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYS
       ::::.::::.: .:::.::::::: ::::::: ::.:::::::.::.:::::::: ::::
XP_011 ATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYS
     490       500       510       520       530       540         

              520       530       540       550       560       570
pF1KB6 HIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIELL
       ::. :::::::::::: ::::::. .::::::.::..::.:  .::::::::::..::::
XP_011 HINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELL
     550       560       570       580       590       600         

              580        590       600        
pF1KB6 QRSLPKIERSASEPSLHRT-QADELPACLLSAARLVP  
       :.:::::.::::::::::. ..... :: :...  .:  
XP_011 QHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
     610       620       630       640        

>>XP_005265415 (OMIM: 164760,611553,611554,615916) PREDI  (567 aa)
 initn: 2205 init1: 1617 opt: 2221  Z-score: 876.8  bits: 172.2 E(85289): 4.2e-42
Smith-Waterman score: 2221; 62.1% identity (80.3% similar) in 549 aa overlap (68-606:27-565)

        40        50        60        70        80        90       
pF1KB6 GMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLT
                                     .:.   :.:  : : :::: :. :. ::::
XP_005     MMANSQILLRQATLSVFSCRTSKEQCKKARLDWNTDAASLIGEELQVDFLDHVPLT
                   10        20        30        40        50      

       100       110       120       130       140       150       
pF1KB6 MHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRQQFYHS
        :::.::::..:::::.: :::..::::::::::::.:::.::::.::: :. :: .   
XP_005 THNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFP
         60        70        80        90       100       110      

       160       170         180       190           200       210 
pF1KB6 VQDLSGGSRQHEAPS--NRPLNELLTPQGPSPRTQHCDPEHFPF----PAPANAPLQRIR
        . . : :     ::   : . : .. .  : . ..  :. : :    :.  ..  :: :
XP_005 NSTI-GDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQR
        120        130       140       150       160       170     

             220       230       240       250       260        270
pF1KB6 STSTPNVHMVSTTAPMDSNLIQLTGQSFSTDAAGSRGGSDGTPRGSPSPASVS-SGRKSP
       ::::::::::::: :.:: .:.        ::  :.. : .    : :: ..: .: ..:
XP_005 STSTPNVHMVSTTLPVDSRMIE--------DAIRSHSESASPSALSSSPNNLSPTGWSQP
         180       190               200       210       220       

              280         290       300       310       320        
pF1KB6 HSKSPAEQRERKSLA--DDKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGR
       ..  :: ::::  ..  ..:.:..  : :::.::::.  :::.:  :::.::::::..:.
XP_005 KTPVPA-QRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGK
       230        240       250       260       270       280      

      330       340       350       360       370       380        
pF1KB6 WHGDVAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGS
       ::::::::.::: .:: :: :::.::. :::::::::::::::.::. ..::.:::::::
XP_005 WHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGS
        290       300       310       320       330       340      

      390       400       410       420       430       440        
pF1KB6 SLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDF
       :::.:::: .:.:.: ::::.::::::::::::::::::::.::::::::::::::::::
XP_005 SLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDF
        350       360       370       380       390       400      

      450       460       470       480       490       500        
pF1KB6 GLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLP
       ::::::.::::.: .:::.::::::: ::::::: ::.:::::::.::.:::::::: ::
XP_005 GLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELP
        410       420       430       440       450       460      

      510       520       530       540       550       560        
pF1KB6 YSHIGCRDQIIFMVGRGYLSPDLSKISSNCPKAMRRLLSDCLKFQREERPLFPQILATIE
       ::::. :::::::::::: ::::::. .::::::.::..::.:  .::::::::::..::
XP_005 YSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIE
        470       480       490       500       510       520      

      570       580        590       600        
pF1KB6 LLQRSLPKIERSASEPSLHRT-QADELPACLLSAARLVP  
       :::.:::::.::::::::::. ..... :: :...  .:  
XP_005 LLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
        530       540       550       560       




606 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 20:33:30 2016 done: Sat Nov  5 20:33:32 2016
 Total Scan time: 11.050 Total Display time:  0.150

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com