Result of FASTA (omim) for pF1KB8434
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8434, 138 aa
  1>>>pF1KB8434 138 - 138 aa - 138 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6081+/-0.000341; mu= 9.8479+/- 0.021
 mean_var=123.8027+/-25.609, 0's: 0 Z-trim(117.4): 307  B-trim: 611 in 2/54
 Lambda= 0.115268
 statistics sampled from 28875 (29408) to 28875 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.345), width:  16
 Scan time:  4.990

The best scores are:                                      opt bits E(85289)
NP_004927 (OMIM: 600431) cyclin-dependent kinase 4 ( 138)  905 160.9 6.2e-40
NP_000068 (OMIM: 155601,155755,600160,606719) cycl ( 156)  682 123.8 9.7e-29
NP_001182061 (OMIM: 155601,155755,600160,606719) c ( 167)  682 123.9   1e-28
XP_011515978 (OMIM: 155601,155755,600160,606719) P ( 172)  682 123.9   1e-28
XP_011515977 (OMIM: 155601,155755,600160,606719) P ( 184)  682 123.9 1.1e-28
XP_005251400 (OMIM: 155601,155755,600160,606719) P ( 105)  522 97.0 7.7e-21
XP_011515981 (OMIM: 155601,155755,600160,606719) P ( 105)  522 97.0 7.7e-21
NP_511042 (OMIM: 600431) cyclin-dependent kinase 4 (  78)  344 67.3 5.2e-12
NP_524145 (OMIM: 600927) cyclin-dependent kinase 4 ( 166)  333 65.8   3e-11
NP_001791 (OMIM: 600927) cyclin-dependent kinase 4 ( 166)  333 65.8   3e-11
NP_001253 (OMIM: 603369) cyclin-dependent kinase 4 ( 168)  289 58.5 4.8e-09
NP_523240 (OMIM: 603369) cyclin-dependent kinase 4 ( 168)  289 58.5 4.8e-09
XP_016884079 (OMIM: 613383) PREDICTED: ankyrin rep ( 235)  216 46.5 2.7e-05
NP_620152 (OMIM: 613383) ankyrin repeat domain-con ( 300)  213 46.2 4.5e-05
XP_016884080 (OMIM: 613383) PREDICTED: ankyrin rep ( 180)  196 43.1 0.00023
XP_011515651 (OMIM: 609172) PREDICTED: protein pho ( 465)  189 42.4 0.00094
NP_001316373 (OMIM: 609172) protein phosphatase 1  ( 528)  175 40.1  0.0051
NP_001316371 (OMIM: 609172) protein phosphatase 1  ( 528)  175 40.1  0.0051
NP_116291 (OMIM: 609172) protein phosphatase 1 reg ( 528)  175 40.1  0.0051
XP_016869403 (OMIM: 609172) PREDICTED: protein pho ( 528)  175 40.1  0.0051
NP_001316372 (OMIM: 609172) protein phosphatase 1  ( 528)  175 40.1  0.0051
NP_001316374 (OMIM: 609172) protein phosphatase 1  ( 528)  175 40.1  0.0051
NP_079511 (OMIM: 607128) tankyrase-2 [Homo sapiens (1166)  177 40.9  0.0068
XP_016872185 (OMIM: 607128) PREDICTED: tankyrase-2 (1169)  177 40.9  0.0068
XP_016863601 (OMIM: 106410,600919) PREDICTED: anky (1689)  179 41.4  0.0069
XP_016863600 (OMIM: 106410,600919) PREDICTED: anky (1755)  179 41.4   0.007
XP_016863599 (OMIM: 106410,600919) PREDICTED: anky (1763)  179 41.4  0.0071
XP_016863598 (OMIM: 106410,600919) PREDICTED: anky (1770)  179 41.4  0.0071
XP_016863597 (OMIM: 106410,600919) PREDICTED: anky (1772)  179 41.4  0.0071
XP_016863596 (OMIM: 106410,600919) PREDICTED: anky (1797)  179 41.4  0.0071
XP_016863595 (OMIM: 106410,600919) PREDICTED: anky (1806)  179 41.4  0.0072
XP_016863594 (OMIM: 106410,600919) PREDICTED: anky (1810)  179 41.4  0.0072
XP_016863592 (OMIM: 106410,600919) PREDICTED: anky (1816)  179 41.4  0.0072
XP_016863593 (OMIM: 106410,600919) PREDICTED: anky (1818)  179 41.4  0.0072
XP_016863591 (OMIM: 106410,600919) PREDICTED: anky (1838)  179 41.4  0.0072
XP_016863590 (OMIM: 106410,600919) PREDICTED: anky (1839)  179 41.4  0.0072
XP_016863589 (OMIM: 106410,600919) PREDICTED: anky (1846)  179 41.4  0.0073
XP_016863588 (OMIM: 106410,600919) PREDICTED: anky (1850)  179 41.4  0.0073
XP_016863587 (OMIM: 106410,600919) PREDICTED: anky (1851)  179 41.4  0.0073
XP_016863586 (OMIM: 106410,600919) PREDICTED: anky (1858)  179 41.4  0.0073
XP_016863585 (OMIM: 106410,600919) PREDICTED: anky (1862)  179 41.4  0.0073
NP_001120965 (OMIM: 106410,600919) ankyrin-2 isofo (1863)  179 41.4  0.0073
XP_016863583 (OMIM: 106410,600919) PREDICTED: anky (1871)  179 41.4  0.0073
XP_016863584 (OMIM: 106410,600919) PREDICTED: anky (1871)  179 41.4  0.0073
NP_066187 (OMIM: 106410,600919) ankyrin-2 isoform  (1872)  179 41.5  0.0073
XP_016863580 (OMIM: 106410,600919) PREDICTED: anky (1879)  179 41.5  0.0074
XP_016863582 (OMIM: 106410,600919) PREDICTED: anky (1881)  179 41.5  0.0074
XP_016863581 (OMIM: 106410,600919) PREDICTED: anky (1882)  179 41.5  0.0074
XP_016863579 (OMIM: 106410,600919) PREDICTED: anky (1886)  179 41.5  0.0074
XP_016863578 (OMIM: 106410,600919) PREDICTED: anky (1887)  179 41.5  0.0074


>>NP_004927 (OMIM: 600431) cyclin-dependent kinase 4 inh  (138 aa)
 initn: 905 init1: 905 opt: 905  Z-score: 838.0  bits: 160.9 E(85289): 6.2e-40
Smith-Waterman score: 905; 99.3% identity (99.3% similar) in 138 aa overlap (1-138:1-138)

               10        20        30        40        50        60
pF1KB8 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMDSAR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_004 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMGSAR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA
               70        80        90       100       110       120

              130        
pF1KB8 EERGHRDVAGYLRTATGD
       ::::::::::::::::::
NP_004 EERGHRDVAGYLRTATGD
              130        

>>NP_000068 (OMIM: 155601,155755,600160,606719) cyclin-d  (156 aa)
 initn: 737 init1: 676 opt: 682  Z-score: 636.9  bits: 123.8 E(85289): 9.7e-29
Smith-Waterman score: 682; 82.0% identity (88.7% similar) in 133 aa overlap (9-137:3-135)

               10            20        30        40        50      
pF1KB8 MREENKGMPSGGGSDEG----LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMM
               :..:.: :     ::.::::: ::.:: :::::: ::. : .::: ::::::
NP_000       MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM
                     10        20        30        40        50    

         60        70        80        90       100       110      
pF1KB8 DSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP
           60        70        80        90       100       110    

        120       130                            
pF1KB8 VDLAEERGHRDVAGYLRTATGD                    
       :::::: :::::: :::.:.:                     
NP_000 VDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD
          120       130       140       150      

>>NP_001182061 (OMIM: 155601,155755,600160,606719) cycli  (167 aa)
 initn: 737 init1: 676 opt: 682  Z-score: 636.6  bits: 123.9 E(85289): 1e-28
Smith-Waterman score: 682; 82.0% identity (88.7% similar) in 133 aa overlap (9-137:3-135)

               10            20        30        40        50      
pF1KB8 MREENKGMPSGGGSDEG----LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMM
               :..:.: :     ::.::::: ::.:: :::::: ::. : .::: ::::::
NP_001       MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM
                     10        20        30        40        50    

         60        70        80        90       100       110      
pF1KB8 DSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP
           60        70        80        90       100       110    

        120       130                                       
pF1KB8 VDLAEERGHRDVAGYLRTATGD                               
       :::::: :::::: :::.:.:                                
NP_001 VDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSEMIGNHLWVCRSRHA
          120       130       140       150       160       

>>XP_011515978 (OMIM: 155601,155755,600160,606719) PREDI  (172 aa)
 initn: 737 init1: 676 opt: 682  Z-score: 636.4  bits: 123.9 E(85289): 1e-28
Smith-Waterman score: 682; 82.0% identity (88.7% similar) in 133 aa overlap (9-137:3-135)

               10            20        30        40        50      
pF1KB8 MREENKGMPSGGGSDEG----LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMM
               :..:.: :     ::.::::: ::.:: :::::: ::. : .::: ::::::
XP_011       MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM
                     10        20        30        40        50    

         60        70        80        90       100       110      
pF1KB8 DSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP
           60        70        80        90       100       110    

        120       130                                            
pF1KB8 VDLAEERGHRDVAGYLRTATGD                                    
       :::::: :::::: :::.:.:                                     
XP_011 VDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSVTASIQVPGGEEGDFGSSYS
          120       130       140       150       160       170  

>>XP_011515977 (OMIM: 155601,155755,600160,606719) PREDI  (184 aa)
 initn: 737 init1: 676 opt: 682  Z-score: 636.1  bits: 123.9 E(85289): 1.1e-28
Smith-Waterman score: 682; 82.0% identity (88.7% similar) in 133 aa overlap (9-137:3-135)

               10            20        30        40        50      
pF1KB8 MREENKGMPSGGGSDEG----LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMM
               :..:.: :     ::.::::: ::.:: :::::: ::. : .::: ::::::
XP_011       MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM
                     10        20        30        40        50    

         60        70        80        90       100       110      
pF1KB8 DSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP
           60        70        80        90       100       110    

        120       130                                              
pF1KB8 VDLAEERGHRDVAGYLRTATGD                                      
       :::::: :::::: :::.:.:                                       
XP_011 VDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSAGWTNLRISKPNCAWHHLEISR
          120       130       140       150       160       170    

>>XP_005251400 (OMIM: 155601,155755,600160,606719) PREDI  (105 aa)
 initn: 585 init1: 522 opt: 522  Z-score: 495.1  bits: 97.0 E(85289): 7.7e-21
Smith-Waterman score: 522; 94.0% identity (96.4% similar) in 84 aa overlap (54-137:1-84)

            30        40        50        60        70        80   
pF1KB8 RGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMDSARVAELLLLHGAEPNCADPATLTRP
                                     ::: ::::::::::::::::::::::::::
XP_005                               MMMGSARVAELLLLHGAEPNCADPATLTRP
                                             10        20        30

            90       100       110       120       130             
pF1KB8 VHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEERGHRDVAGYLRTATGD     
       ::::::::::::::::::::::::::::::::::::::: :::::: :::.:.:      
XP_005 VHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSN
               40        50        60        70        80        90

XP_005 HARIDAAEGPSDIPD
              100     

>>XP_011515981 (OMIM: 155601,155755,600160,606719) PREDI  (105 aa)
 initn: 585 init1: 522 opt: 522  Z-score: 495.1  bits: 97.0 E(85289): 7.7e-21
Smith-Waterman score: 522; 94.0% identity (96.4% similar) in 84 aa overlap (54-137:1-84)

            30        40        50        60        70        80   
pF1KB8 RGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMDSARVAELLLLHGAEPNCADPATLTRP
                                     ::: ::::::::::::::::::::::::::
XP_011                               MMMGSARVAELLLLHGAEPNCADPATLTRP
                                             10        20        30

            90       100       110       120       130             
pF1KB8 VHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEERGHRDVAGYLRTATGD     
       ::::::::::::::::::::::::::::::::::::::: :::::: :::.:.:      
XP_011 VHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSN
               40        50        60        70        80        90

XP_011 HARIDAAEGPSDIPD
              100     

>>NP_511042 (OMIM: 600431) cyclin-dependent kinase 4 inh  (78 aa)
 initn: 387 init1: 344 opt: 344  Z-score: 336.7  bits: 67.3 E(85289): 5.2e-12
Smith-Waterman score: 344; 100.0% identity (100.0% similar) in 53 aa overlap (1-53:1-53)

               10        20        30        40        50        60
pF1KB8 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMDSAR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
NP_511 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA
                                                                   
NP_511 RQGARERGARPRRIGAGT                                          
               70                                                  

>>NP_524145 (OMIM: 600927) cyclin-dependent kinase 4 inh  (166 aa)
 initn: 363 init1: 208 opt: 333  Z-score: 323.0  bits: 65.8 E(85289): 3e-11
Smith-Waterman score: 333; 50.9% identity (75.0% similar) in 116 aa overlap (18-132:12-126)

               10        20        30         40        50         
pF1KB8 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAG-ADPNGVNRFGRRAIQVMMMDSA
                        :..::::: :..::.::.   . :...::::. :.::::. :.
NP_524       MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGST
                     10        20        30        40        50    

      60        70        80        90       100       110         
pF1KB8 RVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL
        .:  :: .:: ::  : .. : ::::::: :::::: :: . :: ..: :. : ::. :
NP_524 AIALELLKQGASPNVQD-TSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHL
           60        70         80        90       100       110   

     120       130                                          
pF1KB8 AEERGHRDVAGYLRTATGD                                  
       : ..::  :...:                                        
NP_524 AVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL
           120       130       140       150       160      

>>NP_001791 (OMIM: 600927) cyclin-dependent kinase 4 inh  (166 aa)
 initn: 363 init1: 208 opt: 333  Z-score: 323.0  bits: 65.8 E(85289): 3e-11
Smith-Waterman score: 333; 50.9% identity (75.0% similar) in 116 aa overlap (18-132:12-126)

               10        20        30         40        50         
pF1KB8 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAG-ADPNGVNRFGRRAIQVMMMDSA
                        :..::::: :..::.::.   . :...::::. :.::::. :.
NP_001       MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGST
                     10        20        30        40        50    

      60        70        80        90       100       110         
pF1KB8 RVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL
        .:  :: .:: ::  : .. : ::::::: :::::: :: . :: ..: :. : ::. :
NP_001 AIALELLKQGASPNVQD-TSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHL
           60        70         80        90       100       110   

     120       130                                          
pF1KB8 AEERGHRDVAGYLRTATGD                                  
       : ..::  :...:                                        
NP_001 AVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL
           120       130       140       150       160      




138 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 01:32:50 2016 done: Sat Nov  5 01:32:51 2016
 Total Scan time:  4.990 Total Display time: -0.040

Function used was FASTA [36.3.4 Apr, 2011]
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