Result of FASTA (ccds) for pF1KA0054
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0054, 1942 aa
  1>>>pF1KA0054 1942 - 1942 aa - 1942 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.6730+/-0.00129; mu= -4.1850+/- 0.077
 mean_var=350.2762+/-72.967, 0's: 0 Z-trim(112.0): 57  B-trim: 294 in 1/51
 Lambda= 0.068528
 statistics sampled from 12752 (12793) to 12752 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.393), width:  16
 Scan time:  4.220

The best scores are:                                      opt bits E(32554)
CCDS42374.1 HELZ gene_id:9931|Hs108|chr17          (1942) 13188 1319.5       0
CCDS82192.1 HELZ gene_id:9931|Hs108|chr17          (1943) 13176 1318.4       0
CCDS33508.1 HELZ2 gene_id:85441|Hs108|chr20        (2649) 1101 124.6   5e-27
CCDS13527.1 HELZ2 gene_id:85441|Hs108|chr20        (2080)  769 91.7 3.2e-17


>>CCDS42374.1 HELZ gene_id:9931|Hs108|chr17               (1942 aa)
 initn: 13188 init1: 13188 opt: 13188  Z-score: 7058.8  bits: 1319.5 E(32554):    0
Smith-Waterman score: 13188; 99.9% identity (100.0% similar) in 1942 aa overlap (1-1942:1-1942)

               10        20        30        40        50        60
pF1KA0 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 LPPVLIIGPYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LPPVLIIGPYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 QARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQ
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 LDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 HVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 HVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPL
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHGI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 TFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQNDH
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 FQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 FQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 GNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPVT
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 IGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 IGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPES
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KA0 RPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 RPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTLL
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KA0 NQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 NQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHRP
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KA0 QSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRIH
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KA0 GSVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQHLPQPPLGLHQPPVRADWK
       :::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
CCDS42 GSVALETLRQQQARFQQWSEHHAFLSQGSAPYPHHHHPHLQHLPQPPLGLHQPPVRADWK
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KA0 LTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVPS
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KA0 PPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAPD
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KA0 GAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 GAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSSS
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KA0 SLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFSS
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KA0 PESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSVL
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KA0 QHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDPL
             1870      1880      1890      1900      1910      1920

             1930      1940  
pF1KA0 SLFQELSLGSSSGSNGFYSYFK
       ::::::::::::::::::::::
CCDS42 SLFQELSLGSSSGSNGFYSYFK
             1930      1940  

>>CCDS82192.1 HELZ gene_id:9931|Hs108|chr17               (1943 aa)
 initn: 8658 init1: 8658 opt: 13176  Z-score: 7052.4  bits: 1318.4 E(32554):    0
Smith-Waterman score: 13176; 99.9% identity (99.9% similar) in 1943 aa overlap (1-1942:1-1943)

               10        20        30        40        50        60
pF1KA0 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MEDRRAEKSCEQACESLKRQDYEMALKHCTEALLSLGQYSMADFTGPCPLEIERIKIESL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDAFRAVLCCMQLKGKLQPVSTILAKSLT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GESLNGMVTKDLTRLKTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 YTLCKRFLEQGICRYGAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EKWMNSLSPEKVLSECIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 DAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 FRQTIVFDFGLEPVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPNE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TTDLEKSLLIRYQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KVQLQILASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KQKLVQTQGTKEKVYEATIEEKTKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 CEMHYALDRIKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLAIQ
              610       620       630       640       650       660

              670       680       690        700       710         
pF1KA0 LPPVLIIGPYGTGKTFTLAQAVKHILQQQET-RILICTHSNSAADLYIKDYLHPYVEAGN
       ::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
CCDS82 LPPVLIIGPYGTGKTFTLAQAVKHILQQQETSRILICTHSNSAADLYIKDYLHPYVEAGN
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KA0 PQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLC
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KA0 QLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 QLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERN
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KA0 LHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYP
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KA0 LTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQ
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KA0 VFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 VFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDS
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KA0 TEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHG
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KA0 ITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQND
             1090      1100      1110      1120      1130      1140

    1140      1150      1160      1170      1180      1190         
pF1KA0 HFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 HFQNDGIVQPNPSVLIGNPIRAYTPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVY
             1150      1160      1170      1180      1190      1200

    1200      1210      1220      1230      1240      1250         
pF1KA0 GGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 GGNVVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQTHGRGSPIPYGLGHHPPV
             1210      1220      1230      1240      1250      1260

    1260      1270      1280      1290      1300      1310         
pF1KA0 TIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TIGQPQNQHQEKDQHEQNRNGKSDTNNSGPEINKIRTPEKKPTEPKQVDLESNPQNRSPE
             1270      1280      1290      1300      1310      1320

    1320      1330      1340      1350      1360      1370         
pF1KA0 SRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SRPSVVYPSTKFPRKDNLNPRHINLPLPAPHAQYAIPNRHFHPLPQLPRPPFPIPQQHTL
             1330      1340      1350      1360      1370      1380

    1380      1390      1400      1410      1420      1430         
pF1KA0 LNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LNQQQNNLPEQPNQIPPQPNQVVQQQSQLNQQPQQPPPQLSPAYQAGPNNAFFNSAVAHR
             1390      1400      1410      1420      1430      1440

    1440      1450      1460      1470      1480      1490         
pF1KA0 PQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 PQSPPAEAVIPEQQPPPMLQEGHSPLRAIAQPGPILPSHLNSFIDENPSGLPIGEALDRI
             1450      1460      1470      1480      1490      1500

    1500      1510      1520      1530      1540      1550         
pF1KA0 HGSVALETLRQQQARFQQWSEHHAFLSQGSVPYPHHHHPHLQHLPQPPLGLHQPPVRADW
       ::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
CCDS82 HGSVALETLRQQQARFQQWSEHHAFLSQGSAPYPHHHHPHLQHLPQPPLGLHQPPVRADW
             1510      1520      1530      1540      1550      1560

    1560      1570      1580      1590      1600      1610         
pF1KA0 KLTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 KLTSSAEDEVETTYSRFQDLIRELSHRDQSETRELAEMPPPQSRLLQYRQVQSRSPPAVP
             1570      1580      1590      1600      1610      1620

    1620      1630      1640      1650      1660      1670         
pF1KA0 SPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SPPSSTDHSSHFSNFNDNSRDIEVASNPAFPQRLPPQIFNSPFSLPSEHLAPPPLKYLAP
             1630      1640      1650      1660      1670      1680

    1680      1690      1700      1710      1720      1730         
pF1KA0 DGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 DGAWTFANLQQNHLMGPGFPYGLPPLPHRPPQNPFVQIQNHQHAIGQEPFHPLSSRTVSS
             1690      1700      1710      1720      1730      1740

    1740      1750      1760      1770      1780      1790         
pF1KA0 SSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SSLPSLEEYEPRGPGRPLYQRRISSSSVQPCSEEVSTPQDSLAQCKELQDHSNQSSFNFS
             1750      1760      1770      1780      1790      1800

    1800      1810      1820      1830      1840      1850         
pF1KA0 SPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SPESWVNTTSSTPYQNIPCNGSSRTAQPRELIAPPKTVKPPEDQLKSENLEVSSSFNYSV
             1810      1820      1830      1840      1850      1860

    1860      1870      1880      1890      1900      1910         
pF1KA0 LQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LQHLGQFPPLMPNKQIAESANSSSPQSSAGGKPAMSYASALRAPPKPRPPPEQAKKSSDP
             1870      1880      1890      1900      1910      1920

    1920      1930      1940  
pF1KA0 LSLFQELSLGSSSGSNGFYSYFK
       :::::::::::::::::::::::
CCDS82 LSLFQELSLGSSSGSNGFYSYFK
             1930      1940   

>>CCDS33508.1 HELZ2 gene_id:85441|Hs108|chr20             (2649 aa)
 initn: 1199 init1: 406 opt: 1101  Z-score: 598.6  bits: 124.6 E(32554): 5e-27
Smith-Waterman score: 1683; 33.8% identity (61.8% similar) in 940 aa overlap (166-1086:76-952)

         140       150       160       170       180       190     
pF1KA0 KTLLSETETATSNALSGYHVEDLDEGSCNGWHFRPPPRGITSSEEYTLCKRFLEQGICRY
                                     :. : :: :..   .. :: .     .:.:
CCDS33 LVTCHSQEAFENHCASSEHAQMVAFDQALPWEHRSPPPGLS---KFELCPK---PDLCEY
          50        60        70        80           90            

         200       210       220       230       240       250     
pF1KA0 GAQCTSAHSQEELAEWQKRYASRLIKLKQQNENKQLSGSYMETLIEKWMNSLSPEKVLSE
       :  ::.::: .:: :: .:  .. ..:. :   ..    :.: :. ... : :   ::.:
CCDS33 GDACTKAHSAQELQEWVRR--TQAVELRGQAAWQDGLVPYQERLLAEYQRSSSEVLVLAE
     100       110         120       130       140       150       

         260       270       280       290       300       310     
pF1KA0 CIEGVKVEHNPDLSVTVSTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAG
        ..::.:  :  :   .. .:.. .::::.  .    : .:::: .     ::..: .  
CCDS33 TLDGVRVTCNQPLMYQAQERKTQYSWTFAVHSEEP--LLHVALLKQEPGADFSLVAPGLP
       160       170       180       190         200       210     

         320          330       340       350       360       370  
pF1KA0 DSTTQVSQE---VPENCQEWIGGKMAQNGLDHYVYKVGIAFNTEIFGTFRQTIVFDFGLE
        .   .  :   :: .  .               ..::.  ..  ::::.: .::::: .
CCDS33 PGRLYARGERFRVPSSTAD---------------FQVGVRVQAASFGTFEQWVVFDFGRR
         220       230                      240       250       260

            380       390       400       410        420       430 
pF1KA0 PVLMQRVMIDAASTEDLEYLMHAKQQLVTTAKRWDSSSKTIIDFEPN-ETTDLEKSLLIR
       :::.:.. .. .. .      .         .:: .... ..   :. : :  . .:. .
CCDS33 PVLLQKLGLQLGQGRRPGPCRNLALGHPEEMERWHTGNRHVV---PGVERTAEQTALMAK
              270       280       290       300          310       

             440       450       460       470       480       490 
pF1KA0 YQIPLSADQLFTQSVLDKSLTKSNYQSRLHDLLYIEEIAQYKEISKFNLKVQLQILASFM
       :. :  : ..  .:: .  .. .::..:.:..:: :: :: . ..:..:. :. . ....
CCDS33 YKGPALALEFNRSSVASGPISPTNYRQRMHQFLYEEEAAQQQLVAKLTLRGQVFLKTALQ
       320       330       340       350       360       370       

             500       510       520       530       540       550 
pF1KA0 LTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPVPKQKLVQTQGTK
         ...    .:  : :...  .  .:  ::  : :.   :... . :::        .  
CCDS33 TPALN--MLFAPPGALYAEVPVPSSLMPDTDQGFLLGRAVSTALVAPVP--------APD
       380         390       400       410       420               

             560         570       580       590       600         
pF1KA0 EKVYEATIEEK--TKEYIFLRLSRECCEELNLRPDCDTQVELQFQLNRLPLCEMHYALDR
       . :.:. .:..  ... ..: :  .::  :.:.:.    .:.:::.. . .   : :.: 
CCDS33 NTVFEVRLERRASSEQALWLLLPARCCLALGLQPEARLVLEVQFQIDPMTFRLWHQAVDT
       430       440       450       460       470       480       

     610       620       630       640       650          660      
pF1KA0 IKDNGVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITT--PL-AIQLPPVLI
       . .. .. ::.  : ..:    : :.     : : ::. ::  :.   :  . ..::.::
CCDS33 LPEEQLVVPDLP-TCALP----RPWSVPPLRRGNRKQELAVALIAGWGPGDGRRVPPLLI
       490        500           510       520       530       540  

        670       680       690       700       710       720      
pF1KA0 IGPYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLR
        ::.:::::.:::.:  ..... ::..:::::.:::::.::..:.: .: .:.:.: :::
CCDS33 YGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATPLR
            550       560       570       580       590       600  

        730       740       750       760       770       780      
pF1KA0 VYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPG
       :.. .: .. . ::. ::: ... ...:. : . .. .:::::.:  :::   .: .  :
CCDS33 VMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVG
            610       620       630       640         650          

        790       800       810       820       830       840      
pF1KA0 FFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLD
       ::.:::.::::: .:::.. ::: :...::.::::::::..: ..:  :: :  . .:: 
CCDS33 FFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLH
     660       670       680       690       700        710        

        850            860       870       880          890        
pF1KA0 RLYEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFY
       ::.  :  :        :... ::::  .::... :. :: .:   . : :: : :   :
CCDS33 RLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHY
      720       730       740       750       760       770        

      900       910       920       930       940       950        
pF1KA0 PLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYAD
       :: :  . :   .. . ... : ::. .:::.:.:    ::  ::  ..  : ::. .. 
CCDS33 PLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS-HGA
      780       790       800       810       820       830        

      960       970       980       990      1000      1010        
pF1KA0 QVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLED
       ::  .: :::.. :..:.:     . :.::::. ::::   :::.   .:     .    
CCDS33 QVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE----
       840       850       860       870          880       890    

     1020      1030      1040      1050      1060      1070        
pF1KA0 STEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL-
               :... ..:::..::::: ..:::: .::::.: : :.:: ::  : :  :. 
CCDS33 --------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVC
                      900       910       920       930       940  

       1080      1090      1100      1110      1120      1130      
pF1KA0 -HGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHT
        .:...::..                                                  
CCDS33 PEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGD
            950       960       970       980       990      1000  

>>CCDS13527.1 HELZ2 gene_id:85441|Hs108|chr20             (2080 aa)
 initn: 905 init1: 229 opt: 769  Z-score: 422.8  bits: 91.7 E(32554): 3.2e-17
Smith-Waterman score: 930; 40.7% identity (66.3% similar) in 398 aa overlap (699-1086:6-383)

      670       680       690       700       710       720        
pF1KA0 PYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVY
                                     : ::::.::..:.: .: .:.:.: ::::.
CCDS13                          MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVM
                                        10        20        30     

      730       740       750       760       770       780        
pF1KA0 FRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQLDLEPGFF
       . .: .. . ::. ::: ... ...:. : . .. .:::::.:  :::   .: .  :::
CCDS13 YTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTT--TSQAR-ELRVPVGFF
          40        50        60        70          80         90  

      790       800       810       820       830       840        
pF1KA0 THILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRL
       .:::.::::: .:::.. ::: :...::.::::::::..: ..:  :: :  . .:: ::
CCDS13 SHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRL
            100       110       120       130        140       150 

      850            860       870       880          890       900
pF1KA0 YEHYPAEF-----PCRILLCENYRSHEAIINYTSELFYEGK---LMASGKQPAHKDFYPL
       .  :  :        :... ::::  .::... :. :: .:   . : :: : :   :::
CCDS13 FLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPL
             160       170       180       190       200       210 

              910       920       930       940       950       960
pF1KA0 TFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQV
        :  . :   .. . ... : ::. .:::.:.:    ::  ::  ..  : ::. .. ::
CCDS13 MFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS-HGAQV
             220       230       240       250       260        270

              970       980       990      1000      1010      1020
pF1KA0 FRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDST
         .: :::.. :..:.:     . :.::::. ::::   :::.   .:     .      
CCDS13 SALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTV---HTCQSLLSPGALAPE------
              280       290       300          310       320       

             1030      1040      1050      1060      1070          
pF1KA0 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL--H
             :... ..:::..::::: ..:::: .::::.: : :.:: ::  : :  :.  .
CCDS13 ------FFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSVCPE
                   330       340       350       360       370     

     1080      1090      1100      1110      1120      1130        
pF1KA0 GITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHSGSTNKQQQSPPKGKSLHHTQN
       :...::..                                                    
CCDS13 GLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEA
         380       390       400       410       420       430     




1942 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Wed Nov  2 17:57:41 2016 done: Wed Nov  2 17:57:42 2016
 Total Scan time:  4.220 Total Display time:  0.280

Function used was FASTA [36.3.4 Apr, 2011]
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