Result of FASTA (omim) for pF1KB6855
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6855, 178 aa
  1>>>pF1KB6855 178 - 178 aa - 178 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9349+/-0.000309; mu= 15.4834+/- 0.019
 mean_var=77.9847+/-15.235, 0's: 0 Z-trim(117.0): 62  B-trim: 23 in 1/53
 Lambda= 0.145234
 statistics sampled from 28653 (28715) to 28653 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.337), width:  16
 Scan time:  4.670

The best scores are:                                      opt bits E(85289)
NP_000563 (OMIM: 124092,180300,609423,614395) inte ( 178) 1187 257.5 8.5e-69
NP_061194 (OMIM: 605619) interleukin-20 precursor  ( 176)  213 53.4 2.3e-07
XP_005273209 (OMIM: 605619) PREDICTED: interleukin ( 261)  213 53.5   3e-07
NP_060872 (OMIM: 605679) interleukin-26 precursor  ( 171)  189 48.3 7.3e-06
XP_011507403 (OMIM: 604136) PREDICTED: interleukin ( 179)  142 38.5   0.007
XP_016855610 (OMIM: 604136) PREDICTED: interleukin ( 179)  142 38.5   0.007
NP_006841 (OMIM: 604136) interleukin-24 isoform 1  ( 206)  142 38.6  0.0077
NP_001172085 (OMIM: 604136) interleukin-24 isoform ( 207)  142 38.6  0.0077


>>NP_000563 (OMIM: 124092,180300,609423,614395) interleu  (178 aa)
 initn: 1187 init1: 1187 opt: 1187  Z-score: 1356.1  bits: 257.5 E(85289): 8.5e-69
Smith-Waterman score: 1187; 100.0% identity (100.0% similar) in 178 aa overlap (1-178:1-178)

               10        20        30        40        50        60
pF1KB6 MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKTLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKTLR
               70        80        90       100       110       120

              130       140       150       160       170        
pF1KB6 LRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN
              130       140       150       160       170        

>>NP_061194 (OMIM: 605619) interleukin-20 precursor [Hom  (176 aa)
 initn: 168 init1:  78 opt: 213  Z-score: 253.3  bits: 53.4 E(85289): 2.3e-07
Smith-Waterman score: 213; 27.0% identity (64.2% similar) in 159 aa overlap (19-169:20-173)

                10        20          30        40        50       
pF1KB6  MHSSALLCCLVLLTGVRASPGQGTQSEN--SCTHFPGNLPNMLRDLRDAFSRVKTFFQM
                          .:. : .. :  ::.     . . :...:..::...   : 
NP_061 MKASSLAFSLLSAAFYLLWTPSTGLKTLNLGSCV-----IATNLQEIRNGFSEIRGSVQA
               10        20        30             40        50     

         60        70         80        90       100       110     
pF1KB6 KD-QLDNLLLKESL-LEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGEN
       :: ..:  .:...  :.: :    :  : .....::..:. . .. :     ...::...
NP_061 KDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLYLDRVFKNYQTPDHYTLRKISSLANS
          60        70        80        90       100       110     

         120       130          140       150        160       170 
pF1KB6 LKTLRLRLRRCHRFLPC---ENKSKAVEQVKNAFNKLQEKG-IYKAMSEFDIFINYIEAY
       . :..  :: ::  . :   :.  :   :. . :.::. .. . ::..:.::.....:  
NP_061 FLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFEKLEPQAAVVKALGELDILLQWMEET
         120       130       140       150       160       170     

              
pF1KB6 MTMKIRN
              
NP_061 E      
              

>>XP_005273209 (OMIM: 605619) PREDICTED: interleukin-20   (261 aa)
 initn: 154 init1:  78 opt: 213  Z-score: 251.1  bits: 53.5 E(85289): 3e-07
Smith-Waterman score: 213; 27.0% identity (64.2% similar) in 159 aa overlap (19-169:105-258)

                           10        20          30        40      
pF1KB6             MHSSALLCCLVLLTGVRASPGQGTQSEN--SCTHFPGNLPNMLRDLRD
                                     .:. : .. :  ::.     . . :...:.
XP_005 LLLWSPDFRPKMKASSLAFSLLSAAFYLLWTPSTGLKTLNLGSCV-----IATNLQEIRN
           80        90       100       110            120         

         50         60        70         80        90       100    
pF1KB6 AFSRVKTFFQMKD-QLDNLLLKESL-LEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPD
       .::...   : :: ..:  .:...  :.: :    :  : .....::..:. . .. :  
XP_005 GFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLYLDRVFKNYQTPDHY
     130       140       150       160       170       180         

          110       120       130          140       150        160
pF1KB6 IKAHVNSLGENLKTLRLRLRRCHRFLPC---ENKSKAVEQVKNAFNKLQEKG-IYKAMSE
          ...::.... :..  :: ::  . :   :.  :   :. . :.::. .. . ::..:
XP_005 TLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFEKLEPQAAVVKALGE
     190       200       210       220       230       240         

              170        
pF1KB6 FDIFINYIEAYMTMKIRN
       .::.....:         
XP_005 LDILLQWMEETE      
     250       260       

>>NP_060872 (OMIM: 605679) interleukin-26 precursor [Hom  (171 aa)
 initn:  92 init1:  78 opt: 189  Z-score: 226.2  bits: 48.3 E(85289): 7.3e-06
Smith-Waterman score: 189; 26.0% identity (60.4% similar) in 169 aa overlap (6-172:6-167)

               10        20        30         40        50         
pF1KB6 MHSSALLCCLVLLTGVRASPGQGTQSENSCTHFP-GNLPNMLRDLRDAFSRVKTFFQMKD
            .: : .::. .  . ..  ::  . . .: :.: . .  :    . .:. .  .:
NP_060 MLVNFILRCGLLLVTLSLAIAKHKQSSFTKSCYPRGTLSQAVDALYIKAAWLKATIP-ED
               10        20        30        40        50          

      60         70        80        90       100       110        
pF1KB6 QLDNL-LLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKT
       .. :. :::..  ..:  . .::   ....:..:.:. : . :       :    :....
NP_060 RIKNIRLLKKKTKKQF--MKNCQFQEQLLSFFMEDVFGQLQLQGCKKIRFV----EDFHS
      60        70          80        90       100           110   

      120       130       140       150       160       170        
pF1KB6 LRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRN
       :: .: .:        . :.. ..:  : .. .::::::.::.::....:.  .      
NP_060 LRQKLSHCISCASSAREMKSITRMKRIFYRIGNKGIYKAISELDILLSWIKKLLESSQ  
           120       130       140       150       160       170   

>>XP_011507403 (OMIM: 604136) PREDICTED: interleukin-24   (179 aa)
 initn:  87 init1:  46 opt: 142  Z-score: 172.8  bits: 38.5 E(85289): 0.007
Smith-Waterman score: 142; 21.9% identity (59.6% similar) in 178 aa overlap (6-174:5-179)

               10          20        30        40        50        
pF1KB6 MHSSALLCCL--VLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMK
            .: ::  .::   ..: .:: . . .  .  : .:   . : .::  ::  .: .
XP_011  MQMVVLPCLGFTLLLWSQVSGAQGQEFHFGPCQVKGVVP---QKLWEAFWAVKDTMQAQ
                10        20        30           40        50      

       60         70        80        90       100         110     
pF1KB6 DQLDNL-LLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKA--HVNSLGEN
       :.. .  ::.. .:.. .   .:  .  ...:::. :. . .:.  ....    ..:..:
XP_011 DNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANN
         60        70        80        90       100       110      

         120          130       140       150        160       170 
pF1KB6 LKTLRLRLRRCHR---FLPCENKSKAVEQVKNAFNKLQ-EKGIYKAMSEFDIFINYIEAY
       .  .  .:.  ..   :   ..  .     . ::..:. : .. ::..: ::...... .
XP_011 FVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKF
        120       130       140       150       160       170      

              
pF1KB6 MTMKIRN
       . .    
XP_011 YKL    
              

>>XP_016855610 (OMIM: 604136) PREDICTED: interleukin-24   (179 aa)
 initn:  87 init1:  46 opt: 142  Z-score: 172.8  bits: 38.5 E(85289): 0.007
Smith-Waterman score: 142; 21.9% identity (59.6% similar) in 178 aa overlap (6-174:5-179)

               10          20        30        40        50        
pF1KB6 MHSSALLCCL--VLLTGVRASPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMK
            .: ::  .::   ..: .:: . . .  .  : .:   . : .::  ::  .: .
XP_016  MQMVVLPCLGFTLLLWSQVSGAQGQEFHFGPCQVKGVVP---QKLWEAFWAVKDTMQAQ
                10        20        30           40        50      

       60         70        80        90       100         110     
pF1KB6 DQLDNL-LLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKA--HVNSLGEN
       :.. .  ::.. .:.. .   .:  .  ...:::. :. . .:.  ....    ..:..:
XP_016 DNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANN
         60        70        80        90       100       110      

         120          130       140       150        160       170 
pF1KB6 LKTLRLRLRRCHR---FLPCENKSKAVEQVKNAFNKLQ-EKGIYKAMSEFDIFINYIEAY
       .  .  .:.  ..   :   ..  .     . ::..:. : .. ::..: ::...... .
XP_016 FVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKF
        120       130       140       150       160       170      

              
pF1KB6 MTMKIRN
       . .    
XP_016 YKL    
              

>>NP_006841 (OMIM: 604136) interleukin-24 isoform 1 prec  (206 aa)
 initn:  87 init1:  46 opt: 142  Z-score: 172.0  bits: 38.6 E(85289): 0.0077
Smith-Waterman score: 142; 21.9% identity (59.6% similar) in 178 aa overlap (6-174:32-206)

                                        10          20        30   
pF1KB6                          MHSSALLCCL--VLLTGVRASPGQGTQSENSCTHF
                                     .: ::  .::   ..: .:: . . .  . 
NP_006 NFQQRLQSLWTLARPFCPPLLATASQMQMVVLPCLGFTLLLWSQVSGAQGQEFHFGPCQV
              10        20        30        40        50        60 

            40        50        60         70        80        90  
pF1KB6 PGNLPNMLRDLRDAFSRVKTFFQMKDQLDNL-LLKESLLEDFKGYLGCQALSEMIQFYLE
        : .:   . : .::  ::  .: .:.. .  ::.. .:.. .   .:  .  ...:::.
NP_006 KGVVP---QKLWEAFWAVKDTMQAQDNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLK
                 70        80        90       100       110        

            100         110       120          130       140       
pF1KB6 EVMPQAENQDPDIKA--HVNSLGENLKTLRLRLRRCHR---FLPCENKSKAVEQVKNAFN
        :. . .:.  ....    ..:..:.  .  .:.  ..   :   ..  .     . ::.
NP_006 TVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFK
      120       130       140       150       160       170        

       150        160       170        
pF1KB6 KLQ-EKGIYKAMSEFDIFINYIEAYMTMKIRN
       .:. : .. ::..: ::...... .. .    
NP_006 QLDVEAALTKALGEVDILLTWMQKFYKL    
      180       190       200          

>>NP_001172085 (OMIM: 604136) interleukin-24 isoform 3 p  (207 aa)
 initn:  87 init1:  46 opt: 142  Z-score: 172.0  bits: 38.6 E(85289): 0.0077
Smith-Waterman score: 142; 21.9% identity (59.6% similar) in 178 aa overlap (6-174:33-207)

                                        10          20        30   
pF1KB6                          MHSSALLCCL--VLLTGVRASPGQGTQSENSCTHF
                                     .: ::  .::   ..: .:: . . .  . 
NP_001 FQQRLQSLWTLASRPFCPPLLATASQMQMVVLPCLGFTLLLWSQVSGAQGQEFHFGPCQV
             10        20        30        40        50        60  

            40        50        60         70        80        90  
pF1KB6 PGNLPNMLRDLRDAFSRVKTFFQMKDQLDNL-LLKESLLEDFKGYLGCQALSEMIQFYLE
        : .:   . : .::  ::  .: .:.. .  ::.. .:.. .   .:  .  ...:::.
NP_001 KGVVP---QKLWEAFWAVKDTMQAQDNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLK
                70        80        90       100       110         

            100         110       120          130       140       
pF1KB6 EVMPQAENQDPDIKA--HVNSLGENLKTLRLRLRRCHR---FLPCENKSKAVEQVKNAFN
        :. . .:.  ....    ..:..:.  .  .:.  ..   :   ..  .     . ::.
NP_001 TVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFK
     120       130       140       150       160       170         

       150        160       170        
pF1KB6 KLQ-EKGIYKAMSEFDIFINYIEAYMTMKIRN
       .:. : .. ::..: ::...... .. .    
NP_001 QLDVEAALTKALGEVDILLTWMQKFYKL    
     180       190       200           




178 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 20:11:11 2016 done: Sat Nov  5 20:11:12 2016
 Total Scan time:  4.670 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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