Result of FASTA (omim) for pF1KE0340
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0340, 507 aa
  1>>>pF1KE0340 507 - 507 aa - 507 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3670+/-0.00036; mu= 18.7936+/- 0.022
 mean_var=81.5746+/-16.704, 0's: 0 Z-trim(114.5): 14  B-trim: 1420 in 2/55
 Lambda= 0.142003
 statistics sampled from 24374 (24388) to 24374 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.286), width:  16
 Scan time:  9.220

The best scores are:                                      opt bits E(85289)
NP_071381 (OMIM: 613159,613553) probable Xaa-Pro a ( 507) 3450 716.7 3.9e-206
NP_000276 (OMIM: 170100,613230) xaa-Pro dipeptidas ( 493)  464 105.0 5.4e-22
NP_001159529 (OMIM: 170100,613230) xaa-Pro dipepti ( 429)  376 86.9 1.3e-16
NP_001159528 (OMIM: 170100,613230) xaa-Pro dipepti ( 452)  316 74.6 6.8e-13
NP_001191756 (OMIM: 613159,613553) probable Xaa-Pr (  55)  158 41.5 0.00075


>>NP_071381 (OMIM: 613159,613553) probable Xaa-Pro amino  (507 aa)
 initn: 3450 init1: 3450 opt: 3450  Z-score: 3821.8  bits: 716.7 E(85289): 3.9e-206
Smith-Waterman score: 3450; 100.0% identity (100.0% similar) in 507 aa overlap (1-507:1-507)

               10        20        30        40        50        60
pF1KE0 MPWLLSAPKLVPAVANVRGLSGCMLCSQRRYSLQPVPERRIPNRYLGQPSPFTHPHLLRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MPWLLSAPKLVPAVANVRGLSGCMLCSQRRYSLQPVPERRIPNRYLGQPSPFTHPHLLRP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 GEVTPGLSQVEYALRRHKLMSLIQKEAQGQSGTDQTVVVLSNPTYYMSNDIPYTFHQDNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GEVTPGLSQVEYALRRHKLMSLIQKEAQGQSGTDQTVVVLSNPTYYMSNDIPYTFHQDNN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 FLYLCGFQEPDSILVLQSLPGKQLPSHKAILFVPRRDPSRELWDGPRSGTDGAIALTGVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FLYLCGFQEPDSILVLQSLPGKQLPSHKAILFVPRRDPSRELWDGPRSGTDGAIALTGVD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 EAYTLEEFQHLLPKMKAETNMVWYDWMRPSHAQLHSDYMQPLTEAKAKSKNKVRGVQQLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 EAYTLEEFQHLLPKMKAETNMVWYDWMRPSHAQLHSDYMQPLTEAKAKSKNKVRGVQQLI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 QRLRLIKSPAEIERMQIAGKLTSQAFIETMFTSKAPVEEAFLYAKFEFECRARGADILAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QRLRLIKSPAEIERMQIAGKLTSQAFIETMFTSKAPVEEAFLYAKFEFECRARGADILAY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 PPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 PPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAEL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 YEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQKLKDLGIMKNIKENNAFKAARKYCPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 YEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQKLKDLGIMKNIKENNAFKAARKYCPH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 HVGHYLGMDVHDTPDMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRGLGVRIEDDVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 HVGHYLGMDVHDTPDMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRGLGVRIEDDVVV
              430       440       450       460       470       480

              490       500       
pF1KE0 TQDSPLILSADCPKEMNDIEQICSQAS
       :::::::::::::::::::::::::::
NP_071 TQDSPLILSADCPKEMNDIEQICSQAS
              490       500       

>>NP_000276 (OMIM: 170100,613230) xaa-Pro dipeptidase is  (493 aa)
 initn: 383 init1: 130 opt: 464  Z-score: 515.8  bits: 105.0 E(85289): 5.4e-22
Smith-Waterman score: 572; 29.3% identity (57.1% similar) in 468 aa overlap (72-500:23-476)

              50        60        70        80        90       100 
pF1KE0 PNRYLGQPSPFTHPHLLRPGEVTPGLSQVEYALRRHKLMSLIQKEAQGQSGTDQTVVVLS
                                     .:: :..:   ..:.   :.:.   .:::.
NP_000         MAAATGPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGS---IVVLQ
                       10        20        30        40            

               110       120       130       140       150         
pF1KE0 N--PTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSLPGKQLPSHKAILFVPRRDPS
       .   :  . .:    :.:.. : .  :  ::    :..   ::      . :::::   :
NP_000 GGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGK------STLFVPRLPAS
      50        60        70        80        90             100   

     160       170       180       190       200       210         
pF1KE0 RELWDGPRSGTDGAIALTGVDEAYTLEEFQHLLPKMKAETNMVWYDWMRPSHAQLHSDYM
       .  : :   . .      .::..  ..:.  .: ..:  . ..    .:  ...  :   
NP_000 HATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQKPSVLLT----LRGVNTDSGSVCR
           110       120       130       140           150         

     220       230       240       250       260       270         
pF1KE0 QPLTEAKAKSKNKVRGVQQLIQRLRLIKSPAEIERMQIAGKLTSQAFIETMFTSKAPVEE
       .   .. .: . .   ..  : . :..:.  :.: .. ..:..:.:  :.: . :. ..:
NP_000 EASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAVKVGMKE
     160       170       180       190       200       210         

     280       290        300       310           320       330    
pF1KE0 AFLYAKFEFECRARGA-DILAYPPVVAGGNRSNTLHY----VKNNQLIKDGEMVLLDGGC
         : . ::  : .::.    .:  . ..:. : .:::    . :.. :..:.: :.: : 
NP_000 YELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGG
     220       230       240       250       260       270         

          340       350       360       370       380       390    
pF1KE0 ESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQ
       :  :..:::: ..:.::.::: :  .:::::. .:  ..   ::.   ... .   .  .
NP_000 EYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLE
     280       290       300       310       320       330         

          400        410       420       430                  440  
pF1KE0 KLKDLGIMK-NIKENNAFKAARKYCPHHVGHYLGMDVHDTPDMP-----------RSL--
       .:  .::.. ..      . .  . :: .::.::.::::.  .:           :::  
NP_000 ELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRT
     340       350       360       370       380       390         

                450                      460       470        480  
pF1KE0 --PLQPGMVITIEPGIYIPED---------------DKDAPEKFRGLG-VRIEDDVVVTQ
          ::::::.:.:::::. .                .... ..:::.: ::::.::::: 
NP_000 ARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVT-
     400       410       420       430       440       450         

            490       500                 
pF1KE0 DSPLILSADCPKEMNDIEQICSQAS          
       :: . : .  :. ...::                 
NP_000 DSGIELLTCVPRTVEEIEACMAGCDKAFTPFSGPK
      460       470       480       490   

>>NP_001159529 (OMIM: 170100,613230) xaa-Pro dipeptidase  (429 aa)
 initn: 339 init1: 130 opt: 376  Z-score: 419.2  bits: 86.9 E(85289): 1.3e-16
Smith-Waterman score: 484; 33.7% identity (61.6% similar) in 294 aa overlap (244-500:120-412)

           220       230       240       250       260       270   
pF1KE0 LHSDYMQPLTEAKAKSKNKVRGVQQLIQRLRLIKSPAEIERMQIAGKLTSQAFIETMFTS
                                     :..:.  :.: .. ..:..:.:  :.: . 
NP_001 SGSVCREASFDGISKFEVNNTILHPEIVECRVFKTDMELEVLRYTNKISSEAHREVMKAV
      90       100       110       120       130       140         

           280       290        300       310           320        
pF1KE0 KAPVEEAFLYAKFEFECRARGA-DILAYPPVVAGGNRSNTLHY----VKNNQLIKDGEMV
       :. ..:  : . ::  : .::.    .:  . ..:. : .:::    . :.. :..:.: 
NP_001 KVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMC
     150       160       170       180       190       200         

      330       340       350       360       370       380        
pF1KE0 LLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRDCLALCFPGTSLENIYSMM
       :.: : :  :..:::: ..:.::.::: :  .:::::. .:  ..   ::.   ... . 
NP_001 LFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLA
     210       220       230       240       250       260         

      390       400        410       420       430                 
pF1KE0 LTLIGQKLKDLGIMK-NIKENNAFKAARKYCPHHVGHYLGMDVHDTPDMP----------
         .  ..:  .::.. ..      . .  . :: .::.::.::::.  .:          
NP_001 DRIHLEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPG
     270       280       290       300       310       320         

        440           450                      460       470       
pF1KE0 -RSL----PLQPGMVITIEPGIYIPED---------------DKDAPEKFRGLG-VRIED
        :::     ::::::.:.:::::. .                .... ..:::.: ::::.
NP_001 LRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEE
     330       340       350       360       370       380         

        480       490       500                 
pF1KE0 DVVVTQDSPLILSADCPKEMNDIEQICSQAS          
       ::::: :: . : .  :. ...::                 
NP_001 DVVVT-DSGIELLTCVPRTVEEIEACMAGCDKAFTPFSGPK
     390        400       410       420         

>>NP_001159528 (OMIM: 170100,613230) xaa-Pro dipeptidase  (452 aa)
 initn: 383 init1: 130 opt: 316  Z-score: 352.5  bits: 74.6 E(85289): 6.8e-13
Smith-Waterman score: 453; 27.6% identity (51.5% similar) in 468 aa overlap (72-500:23-435)

              50        60        70        80        90       100 
pF1KE0 PNRYLGQPSPFTHPHLLRPGEVTPGLSQVEYALRRHKLMSLIQKEAQGQSGTDQTVVVLS
                                     .:: :..:   ..:.   :.:.   .:::.
NP_001         MAAATGPSFWLGNETLKVPLALFALNRQRLCERLRKNPAVQAGS---IVVLQ
                       10        20        30        40            

               110       120       130       140       150         
pF1KE0 N--PTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSLPGKQLPSHKAILFVPRRDPS
       .   :  . .:    :.:.. : .  :  ::    :..   ::      . :::::   :
NP_001 GGEETQRYCTDTGVLFRQESFFHWAFGVTEPGCYGVIDVDTGK------STLFVPRLPAS
      50        60        70        80        90             100   

     160       170       180       190       200       210         
pF1KE0 RELWDGPRSGTDGAIALTGVDEAYTLEEFQHLLPKMKAETNMVWYDWMRPSHAQLHSDYM
       .  : :   . .      .::..  ..:.  .: ..:            ::        .
NP_001 HATWMGKIHSKEHFKEKYAVDDVQYVDEIASVLTSQK------------PS-------VL
           110       120       130       140                       

     220       230       240       250       260       270         
pF1KE0 QPLTEAKAKSKNKVRGVQQLIQRLRLIKSPAEIERMQIAGKLTSQAFIETMFTSKAPVEE
         :  ... : .  : .           :   : .... . .    ..: .         
NP_001 LTLRGVNTDSGSVCREA-----------SFDGISKFEVNNTILHPEIVECL---------
          150       160                  170       180             

     280       290        300       310           320       330    
pF1KE0 AFLYAKFEFECRARGA-DILAYPPVVAGGNRSNTLHY----VKNNQLIKDGEMVLLDGGC
             ::  : .::.    .:  . ..:. : .:::    . :.. :..:.: :.: : 
NP_001 ------FEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGG
                190       200       210       220       230        

          340       350       360       370       380       390    
pF1KE0 ESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQ
       :  :..:::: ..:.::.::: :  .:::::. .:  ..   ::.   ... .   .  .
NP_001 EYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLADRIHLE
      240       250       260       270       280       290        

          400        410       420       430                  440  
pF1KE0 KLKDLGIMK-NIKENNAFKAARKYCPHHVGHYLGMDVHDTPDMP-----------RSL--
       .:  .::.. ..      . .  . :: .::.::.::::.  .:           :::  
NP_001 ELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLGIDVHDVGGYPEGVERIDEPGLRSLRT
      300       310       320       330       340       350        

                450                      460       470        480  
pF1KE0 --PLQPGMVITIEPGIYIPED---------------DKDAPEKFRGLG-VRIEDDVVVTQ
          ::::::.:.:::::. .                .... ..:::.: ::::.::::: 
NP_001 ARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGVRIEEDVVVT-
      360       370       380       390       400       410        

            490       500                 
pF1KE0 DSPLILSADCPKEMNDIEQICSQAS          
       :: . : .  :. ...::                 
NP_001 DSGIELLTCVPRTVEEIEACMAGCDKAFTPFSGPK
       420       430       440       450  

>>NP_001191756 (OMIM: 613159,613553) probable Xaa-Pro am  (55 aa)
 initn: 170 init1: 156 opt: 158  Z-score: 190.1  bits: 41.5 E(85289): 0.00075
Smith-Waterman score: 158; 60.0% identity (71.1% similar) in 45 aa overlap (1-39:1-45)

               10        20        30              40        50    
pF1KE0 MPWLLSAPKLVPAVANVRGLSGCMLCSQRRY------SLQPVPERRIPNRYLGQPSPFTH
       :::::::::::::::::::::: .. .:         .:::.  :               
NP_001 MPWLLSAPKLVPAVANVRGLSGSYFVTQAGVQWRDPITLQPMSSRLKQSFYQLPE     
               10        20        30        40        50          

           60        70        80        90       100       110    
pF1KE0 PHLLRPGEVTPGLSQVEYALRRHKLMSLIQKEAQGQSGTDQTVVVLSNPTYYMSNDIPYT




507 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 15:13:11 2016 done: Thu Nov  3 15:13:13 2016
 Total Scan time:  9.220 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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