Result of FASTA (omim) for pF1KB7314
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7314, 1079 aa
  1>>>pF1KB7314 1079 - 1079 aa - 1079 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.6150+/-0.000449; mu= 2.3276+/- 0.028
 mean_var=248.7737+/-53.125, 0's: 0 Z-trim(119.0): 159  B-trim: 1076 in 1/54
 Lambda= 0.081315
 statistics sampled from 32286 (32497) to 32286 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.381), width:  16
 Scan time: 14.320

The best scores are:                                      opt bits E(85289)
NP_872601 (OMIM: 400009) histone demethylase UTY i (1079) 7275 867.7       0
NP_872600 (OMIM: 400009) histone demethylase UTY i (1240) 6668 796.5       0
NP_001245192 (OMIM: 400009) histone demethylase UT (1290) 6668 796.5       0
NP_001245196 (OMIM: 400009) histone demethylase UT (1342) 6668 796.5       0
XP_016885558 (OMIM: 400009) PREDICTED: histone dem (1342) 6668 796.5       0
NP_009056 (OMIM: 400009) histone demethylase UTY i (1347) 6668 796.5       0
XP_016885557 (OMIM: 400009) PREDICTED: histone dem (1347) 6668 796.5       0
XP_011529754 (OMIM: 400009) PREDICTED: histone dem (1485) 6668 796.6       0
NP_001278346 (OMIM: 147920,300128,300867) lysine-s (1356) 5577 668.6 6.9e-191
XP_011542274 (OMIM: 147920,300128,300867) PREDICTE (1392) 5577 668.6 7.1e-191
NP_001245194 (OMIM: 400009) histone demethylase UT (1264) 5277 633.3 2.6e-180
XP_011542275 (OMIM: 147920,300128,300867) PREDICTE (1375) 4890 588.0 1.3e-166
XP_011542270 (OMIM: 147920,300128,300867) PREDICTE (1411) 4890 588.0 1.3e-166
XP_011529764 (OMIM: 400009) PREDICTED: histone dem (1154) 4712 567.0 2.2e-160
XP_011529766 (OMIM: 400009) PREDICTED: histone dem (1124) 4687 564.1 1.6e-159
NP_001245188 (OMIM: 400009) histone demethylase UT (1331) 4655 560.4 2.5e-158
XP_011529763 (OMIM: 400009) PREDICTED: histone dem (1176) 4639 558.5 8.3e-158
NP_001245189 (OMIM: 400009) histone demethylase UT (1377) 4189 505.7 7.3e-142
XP_011529752 (OMIM: 400009) PREDICTED: histone dem (1515) 4189 505.8 7.9e-142
NP_001245190 (OMIM: 400009) histone demethylase UT (1389) 4139 499.9 4.3e-140
XP_011529760 (OMIM: 400009) PREDICTED: histone dem (1422) 4105 495.9 6.9e-139
XP_016885555 (OMIM: 400009) PREDICTED: histone dem (1422) 4105 495.9 6.9e-139
XP_005262575 (OMIM: 400009) PREDICTED: histone dem (1182) 4080 492.9 4.6e-138
NP_001278350 (OMIM: 147920,300128,300867) lysine-s (1105) 4079 492.8 4.7e-138
NP_001245185 (OMIM: 400009) histone demethylase UT (1335) 4080 492.9  5e-138
NP_001245195 (OMIM: 400009) histone demethylase UT (1367) 4080 492.9 5.1e-138
XP_016885556 (OMIM: 400009) PREDICTED: histone dem (1387) 4080 492.9 5.2e-138
NP_001245181 (OMIM: 400009) histone demethylase UT (1392) 4080 492.9 5.2e-138
XP_011529751 (OMIM: 400009) PREDICTED: histone dem (1530) 4080 493.0 5.6e-138
NP_001245193 (OMIM: 400009) histone demethylase UT (1376) 4038 488.0 1.6e-136
XP_006724938 (OMIM: 400009) PREDICTED: histone dem (1234) 4032 487.3 2.4e-136
NP_001245187 (OMIM: 400009) histone demethylase UT (1399) 4032 487.3 2.6e-136
NP_001245178 (OMIM: 400009) histone demethylase UT (1444) 4032 487.3 2.7e-136
XP_011529749 (OMIM: 400009) PREDICTED: histone dem (1537) 4032 487.3 2.8e-136
XP_011529744 (OMIM: 400009) PREDICTED: histone dem (1582) 4032 487.4 2.9e-136
XP_016885562 (OMIM: 400009) PREDICTED: histone dem (1063) 3991 482.4 5.9e-135
XP_011529767 (OMIM: 400009) PREDICTED: histone dem (1095) 3991 482.4  6e-135
NP_001245182 (OMIM: 400009) histone demethylase UT (1306) 3991 482.5 6.9e-135
NP_001245180 (OMIM: 400009) histone demethylase UT (1363) 3991 482.5 7.1e-135
XP_011529753 (OMIM: 400009) PREDICTED: histone dem (1501) 3991 482.5 7.7e-135
XP_011529765 (OMIM: 400009) PREDICTED: histone dem (1140) 3364 408.9 8.6e-113
XP_016885561 (OMIM: 400009) PREDICTED: histone dem (1125) 3346 406.8 3.7e-112
XP_011529762 (OMIM: 400009) PREDICTED: histone dem (1192) 3346 406.8 3.8e-112
NP_001245199 (OMIM: 400009) histone demethylase UT (1218) 3149 383.7 3.5e-105
NP_001245186 (OMIM: 400009) histone demethylase UT (1223) 3149 383.7 3.6e-105
XP_016885273 (OMIM: 147920,300128,300867) PREDICTE (1193) 3122 380.5 3.1e-104
XP_011542277 (OMIM: 147920,300128,300867) PREDICTE (1238) 3117 379.9 4.8e-104
XP_016885274 (OMIM: 147920,300128,300867) PREDICTE (1071) 2892 353.5 3.8e-96
NP_001245191 (OMIM: 400009) histone demethylase UT (1320) 2798 342.5 9.4e-93
XP_011529747 (OMIM: 400009) PREDICTED: histone dem (1553) 2765 338.7 1.6e-91


>>NP_872601 (OMIM: 400009) histone demethylase UTY isofo  (1079 aa)
 initn: 7275 init1: 7275 opt: 7275  Z-score: 4625.9  bits: 867.7 E(85289):    0
Smith-Waterman score: 7275; 100.0% identity (100.0% similar) in 1079 aa overlap (1-1079:1-1079)

               10        20        30        40        50        60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070         
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR
             1030      1040      1050      1060      1070         

>>NP_872600 (OMIM: 400009) histone demethylase UTY isofo  (1240 aa)
 initn: 6668 init1: 6668 opt: 6668  Z-score: 4240.2  bits: 796.5 E(85289):    0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)

               10        20        30        40        50        60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_872 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
       :::::::::::::::::::::::::::::::::::                         
NP_872 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070          
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR 
                                                                   
NP_872 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
             1030      1040      1050      1060      1070      1080

>>NP_001245192 (OMIM: 400009) histone demethylase UTY is  (1290 aa)
 initn: 6668 init1: 6668 opt: 6668  Z-score: 4240.0  bits: 796.5 E(85289):    0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)

               10        20        30        40        50        60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
       :::::::::::::::::::::::::::::::::::                         
NP_001 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070          
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR 
                                                                   
NP_001 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
             1030      1040      1050      1060      1070      1080

>>NP_001245196 (OMIM: 400009) histone demethylase UTY is  (1342 aa)
 initn: 6668 init1: 6668 opt: 6668  Z-score: 4239.7  bits: 796.5 E(85289):    0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)

               10        20        30        40        50        60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
       :::::::::::::::::::::::::::::::::::                         
NP_001 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070          
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR 
                                                                   
NP_001 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
             1030      1040      1050      1060      1070      1080

>>XP_016885558 (OMIM: 400009) PREDICTED: histone demethy  (1342 aa)
 initn: 6668 init1: 6668 opt: 6668  Z-score: 4239.7  bits: 796.5 E(85289):    0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)

               10        20        30        40        50        60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
       :::::::::::::::::::::::::::::::::::                         
XP_016 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070          
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR 
                                                                   
XP_016 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
             1030      1040      1050      1060      1070      1080

>>NP_009056 (OMIM: 400009) histone demethylase UTY isofo  (1347 aa)
 initn: 6668 init1: 6668 opt: 6668  Z-score: 4239.7  bits: 796.5 E(85289):    0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)

               10        20        30        40        50        60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
       :::::::::::::::::::::::::::::::::::                         
NP_009 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070          
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR 
                                                                   
NP_009 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
             1030      1040      1050      1060      1070      1080

>>XP_016885557 (OMIM: 400009) PREDICTED: histone demethy  (1347 aa)
 initn: 6668 init1: 6668 opt: 6668  Z-score: 4239.7  bits: 796.5 E(85289):    0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)

               10        20        30        40        50        60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
       :::::::::::::::::::::::::::::::::::                         
XP_016 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070          
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR 
                                                                   
XP_016 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
             1030      1040      1050      1060      1070      1080

>>XP_011529754 (OMIM: 400009) PREDICTED: histone demethy  (1485 aa)
 initn: 6668 init1: 6668 opt: 6668  Z-score: 4239.1  bits: 796.6 E(85289):    0
Smith-Waterman score: 6668; 100.0% identity (100.0% similar) in 995 aa overlap (1-995:1-995)

               10        20        30        40        50        60
pF1KB7 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB7 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB7 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB7 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPGFKRFSHLS
       :::::::::::::::::::::::::::::::::::                         
XP_011 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070          
pF1KB7 LPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGITGVSHHAR 
                                                                   
XP_011 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
             1030      1040      1050      1060      1070      1080

>>NP_001278346 (OMIM: 147920,300128,300867) lysine-speci  (1356 aa)
 initn: 4193 init1: 2531 opt: 5577  Z-score: 3548.0  bits: 668.6 E(85289): 6.9e-191
Smith-Waterman score: 5577; 84.1% identity (92.8% similar) in 1003 aa overlap (1-995:1-1003)

               10           20        30        40        50       
pF1KB7 MKSCAVSLTTAAVA---FGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV
       ::::.:::.:::.:   :::: :::: :::: :::: : :::.::::::::.::::::::
NP_001 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB7 RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY
       :.::::::::.:::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB7 SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN
       :::.:::::::::::::::::.::::.:::::::.:::::::::::::::::::::::::
NP_001 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
              130       140       150       160       170       180

       180       190       200       210       220       230       
pF1KB7 TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ
       :::.::::::::::.:::::::::::::::::::::::::::::::::::::::::: ::
NP_001 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
              190       200       210       220       230       240

       240       250       260       270       280       290       
pF1KB7 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       ::::::::::::::..::.:::::::::::::::::::::::::::::::::::::::::
NP_001 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KB7 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KB7 LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQ-VY
       ::::::::::::::::::.::: :::::.::::::.::: ::::.::...:: :::: ..
NP_001 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQNTSDNWSGGHAVSHPPVQQQAH
              370       380       390       400       410       420

        420       430       440       450         460       470    
pF1KB7 SLCLTPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQ--MRHKEVAQVRTTGIHN
       : :::::::::::::::::.::::::: .:::::::::::::  ::   :::::.::: :
NP_001 SWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPN
              430       440       450       460       470       480

          480       490       500       510       520       530    
pF1KB7 GAITDSSLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKIL
       :  .::::::::::..::. ::::: :::::::::::  . :..: :::: .::.::. :
NP_001 GPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTL
              490       500       510       520       530       540

          540       550       560       570       580       590    
pF1KB7 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHK
       :::::::.:.: :.:: :::::::::.:. :::::.:.:.::.::::..:::::.:::::
NP_001 GSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHK
              550       560       570       580       590       600

          600       610       620       630       640       650    
pF1KB7 SQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTAT
       .:::  .::: :.:: ::: .:. ::...::.. : : ::::::: :: : .::: ::::
NP_001 GQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTAT
              610       620       630       640       650       660

          660       670       680       690       700       710    
pF1KB7 SGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHG
       ::::::: .::::::: :   :::::::::.: :. :.:.:: :::::. :::: ::.::
NP_001 SGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHG
              670       680       690       700       710       720

            720       730       740       750       760       770  
pF1KB7 DS--PNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAIST
       ::  :.:: .:::::::::.::::.::::::::::::::::::::::.::::::::::::
NP_001 DSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAIST
              730       740       750       760       770       780

            780       790       800       810       820       830  
pF1KB7 ATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSM
       :::::::::: . :::::::::::::::.::::. .:::  :.:: :..:. . ::.:::
NP_001 ATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSM
              790       800       810       820       830       840

            840       850       860       870       880       890  
pF1KB7 SVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYL
       :::: :::.:::::::: :::::::: ::::::::::::.::::::::::::::::::::
NP_001 SVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYL
              850       860       870       880       890       900

            900       910       920       930       940       950  
pF1KB7 ENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLL
       ::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_001 ENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLL
              910       920       930       940       950       960

            960       970       980       990      1000      1010  
pF1KB7 QPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPG
       ::::::::::::::::.::::::::::::::::::::::::::                 
NP_001 QPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSES
              970       980       990      1000      1010      1020

           1020      1030      1040      1050      1060      1070  
pF1KB7 FKRFSHLSLPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGIT
                                                                   
NP_001 TSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHT
             1030      1040      1050      1060      1070      1080

>>XP_011542274 (OMIM: 147920,300128,300867) PREDICTED: l  (1392 aa)
 initn: 4193 init1: 2531 opt: 5577  Z-score: 3547.8  bits: 668.6 E(85289): 7.1e-191
Smith-Waterman score: 5577; 84.1% identity (92.8% similar) in 1003 aa overlap (1-995:1-1003)

               10           20        30        40        50       
pF1KB7 MKSCAVSLTTAAVA---FGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV
       ::::.:::.:::.:   :::: :::: :::: :::: : :::.::::::::.::::::::
XP_011 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB7 RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY
       :.::::::::.:::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB7 SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN
       :::.:::::::::::::::::.::::.:::::::.:::::::::::::::::::::::::
XP_011 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
              130       140       150       160       170       180

       180       190       200       210       220       230       
pF1KB7 TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ
       :::.::::::::::.:::::::::::::::::::::::::::::::::::::::::: ::
XP_011 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
              190       200       210       220       230       240

       240       250       260       270       280       290       
pF1KB7 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
       ::::::::::::::..::.:::::::::::::::::::::::::::::::::::::::::
XP_011 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KB7 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KB7 LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQ-VY
       ::::::::::::::::::.::: :::::.::::::.::: ::::.::...:: :::: ..
XP_011 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQNTSDNWSGGHAVSHPPVQQQAH
              370       380       390       400       410       420

        420       430       440       450         460       470    
pF1KB7 SLCLTPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQ--MRHKEVAQVRTTGIHN
       : :::::::::::::::::.::::::: .:::::::::::::  ::   :::::.::: :
XP_011 SWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPN
              430       440       450       460       470       480

          480       490       500       510       520       530    
pF1KB7 GAITDSSLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKIL
       :  .::::::::::..::. ::::: :::::::::::  . :..: :::: .::.::. :
XP_011 GPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTL
              490       500       510       520       530       540

          540       550       560       570       580       590    
pF1KB7 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHK
       :::::::.:.: :.:: :::::::::.:. :::::.:.:.::.::::..:::::.:::::
XP_011 GSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHK
              550       560       570       580       590       600

          600       610       620       630       640       650    
pF1KB7 SQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTAT
       .:::  .::: :.:: ::: .:. ::...::.. : : ::::::: :: : .::: ::::
XP_011 GQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTAT
              610       620       630       640       650       660

          660       670       680       690       700       710    
pF1KB7 SGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHG
       ::::::: .::::::: :   :::::::::.: :. :.:.:: :::::. :::: ::.::
XP_011 SGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHG
              670       680       690       700       710       720

            720       730       740       750       760       770  
pF1KB7 DS--PNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAIST
       ::  :.:: .:::::::::.::::.::::::::::::::::::::::.::::::::::::
XP_011 DSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAIST
              730       740       750       760       770       780

            780       790       800       810       820       830  
pF1KB7 ATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSM
       :::::::::: . :::::::::::::::.::::. .:::  :.:: :..:. . ::.:::
XP_011 ATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSM
              790       800       810       820       830       840

            840       850       860       870       880       890  
pF1KB7 SVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYL
       :::: :::.:::::::: :::::::: ::::::::::::.::::::::::::::::::::
XP_011 SVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYL
              850       860       870       880       890       900

            900       910       920       930       940       950  
pF1KB7 ENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLL
       ::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_011 ENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLL
              910       920       930       940       950       960

            960       970       980       990      1000      1010  
pF1KB7 QPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLRAGMQWCDLSSLQPPPPG
       ::::::::::::::::.::::::::::::::::::::::::::                 
XP_011 QPADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSES
              970       980       990      1000      1010      1020

           1020      1030      1040      1050      1060      1070  
pF1KB7 FKRFSHLSLPNSWNYRHLPSCPTNFCIFVETGFHHVGQACLELLTSGGLLASASQSAGIT
                                                                   
XP_011 TSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHT
             1030      1040      1050      1060      1070      1080




1079 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 08:34:38 2016 done: Sat Nov  5 08:34:41 2016
 Total Scan time: 14.320 Total Display time:  0.540

Function used was FASTA [36.3.4 Apr, 2011]
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