Result of FASTA (omim) for pF1KE0464
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0464, 222 aa
  1>>>pF1KE0464 222 - 222 aa - 222 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.2543+/-0.000325; mu= 9.3700+/- 0.020
 mean_var=83.8383+/-16.548, 0's: 0 Z-trim(116.3): 32  B-trim: 211 in 2/51
 Lambda= 0.140073
 statistics sampled from 27336 (27368) to 27336 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.321), width:  16
 Scan time:  6.300

The best scores are:                                      opt bits E(85289)
XP_011529968 (OMIM: 612535) PREDICTED: THAP domain ( 222) 1533 319.1 3.6e-87
XP_011529969 (OMIM: 612535) PREDICTED: THAP domain ( 222) 1533 319.1 3.6e-87
NP_653322 (OMIM: 612535) THAP domain-containing pr ( 222) 1533 319.1 3.6e-87
XP_005262829 (OMIM: 612535) PREDICTED: THAP domain ( 181) 1240 259.9   2e-69
XP_005262831 (OMIM: 612535) PREDICTED: THAP domain ( 160)  982 207.7 8.9e-54
XP_016863290 (OMIM: 612535) PREDICTED: THAP domain ( 147)  970 205.3 4.4e-53
XP_006714172 (OMIM: 612535) PREDICTED: THAP domain ( 172)  967 204.7 7.8e-53
NP_001304720 (OMIM: 612535) THAP domain-containing ( 180)  679 146.5 2.7e-35
XP_016863289 (OMIM: 612535) PREDICTED: THAP domain ( 180)  679 146.5 2.7e-35
NP_078948 (OMIM: 612537) DNA transposase THAP9 iso ( 903)  310 72.2 3.1e-12
NP_113623 (OMIM: 612531) THAP domain-containing pr ( 228)  220 53.8 2.7e-07
NP_085050 (OMIM: 609518) THAP domain-containing pr ( 309)  220 53.9 3.6e-07
NP_001008695 (OMIM: 609518) THAP domain-containing ( 309)  220 53.9 3.6e-07
NP_060575 (OMIM: 602629,609520) THAP domain-contai ( 213)  211 52.0 9.1e-07
XP_016864092 (OMIM: 612537) PREDICTED: DNA transpo ( 916)  217 53.4 1.4e-06
NP_057047 (OMIM: 612533) THAP domain-containing pr ( 577)  200 49.9   1e-05
XP_005247073 (OMIM: 612533) PREDICTED: THAP domain ( 711)  200 50.0 1.2e-05
NP_001123947 (OMIM: 612534) THAP domain-containing ( 395)  188 47.4 3.9e-05
XP_011540703 (OMIM: 612532) PREDICTED: THAP domain ( 148)  176 44.8 8.9e-05
XP_016858250 (OMIM: 612532) PREDICTED: THAP domain ( 168)  176 44.9  0.0001
NP_612359 (OMIM: 612532) THAP domain-containing pr ( 175)  176 44.9  0.0001
NP_001182682 (OMIM: 612532) THAP domain-containing ( 239)  176 44.9 0.00014
NP_001182681 (OMIM: 612532) THAP domain-containing ( 238)  174 44.5 0.00018
XP_005263589 (OMIM: 612532) PREDICTED: THAP domain ( 238)  174 44.5 0.00018
NP_004696 (OMIM: 607374) 52 kDa repressor of the i ( 761)  155 40.9  0.0071


>>XP_011529968 (OMIM: 612535) PREDICTED: THAP domain-con  (222 aa)
 initn: 1533 init1: 1533 opt: 1533  Z-score: 1686.0  bits: 319.1 E(85289): 3.6e-87
Smith-Waterman score: 1533; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222)

               10        20        30        40        50        60
pF1KE0 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 HLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
              130       140       150       160       170       180

              190       200       210       220  
pF1KE0 KSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS
       ::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS
              190       200       210       220  

>>XP_011529969 (OMIM: 612535) PREDICTED: THAP domain-con  (222 aa)
 initn: 1533 init1: 1533 opt: 1533  Z-score: 1686.0  bits: 319.1 E(85289): 3.6e-87
Smith-Waterman score: 1533; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222)

               10        20        30        40        50        60
pF1KE0 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 HLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
              130       140       150       160       170       180

              190       200       210       220  
pF1KE0 KSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS
       ::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS
              190       200       210       220  

>>NP_653322 (OMIM: 612535) THAP domain-containing protei  (222 aa)
 initn: 1533 init1: 1533 opt: 1533  Z-score: 1686.0  bits: 319.1 E(85289): 3.6e-87
Smith-Waterman score: 1533; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222)

               10        20        30        40        50        60
pF1KE0 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 HLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 HLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
              130       140       150       160       170       180

              190       200       210       220  
pF1KE0 KSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS
       ::::::::::::::::::::::::::::::::::::::::::
NP_653 KSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS
              190       200       210       220  

>>XP_005262829 (OMIM: 612535) PREDICTED: THAP domain-con  (181 aa)
 initn: 1240 init1: 1240 opt: 1240  Z-score: 1367.4  bits: 259.9 E(85289): 2e-69
Smith-Waterman score: 1240; 100.0% identity (100.0% similar) in 181 aa overlap (42-222:1-181)

              20        30        40        50        60        70 
pF1KE0 SRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDVLCSRHFKKTDF
                                     ::::::::::::::::::::::::::::::
XP_005                               MKRLDVNAAGIWEPKKGDVLCSRHFKKTDF
                                             10        20        30

              80        90       100       110       120       130 
pF1KE0 DRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNHHLVGASSCIEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNHHLVGASSCIEE
               40        50        60        70        80        90

             140       150       160       170       180       190 
pF1KE0 FQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQKSLRKTIRELK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQKSLRKTIRELK
              100       110       120       130       140       150

             200       210       220  
pF1KE0 DECLISQETANRLDTFCWDCCQESIEQDYIS
       :::::::::::::::::::::::::::::::
XP_005 DECLISQETANRLDTFCWDCCQESIEQDYIS
              160       170       180 

>>XP_005262831 (OMIM: 612535) PREDICTED: THAP domain-con  (160 aa)
 initn: 999 init1: 978 opt: 982  Z-score: 1086.4  bits: 207.7 E(85289): 8.9e-54
Smith-Waterman score: 982; 88.7% identity (94.3% similar) in 159 aa overlap (1-159:1-159)

               10        20        30        40        50        60
pF1KE0 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 HLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
       ::::::::::::::::::.:    ... .. : . .. :                     
XP_005 HLVGASSCIEEFQSQFIFKHRKRKQEQEEEQKPRREKCIS                    
              130       140       150       160                    

              190       200       210       220  
pF1KE0 KSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS

>>XP_016863290 (OMIM: 612535) PREDICTED: THAP domain-con  (147 aa)
 initn: 991 init1: 970 opt: 970  Z-score: 1073.9  bits: 205.3 E(85289): 4.4e-53
Smith-Waterman score: 970; 97.9% identity (99.3% similar) in 141 aa overlap (1-141:1-141)

               10        20        30        40        50        60
pF1KE0 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 HLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
       :::::::::::::::::: ..                                       
XP_016 HLVGASSCIEEFQSQFIFTYTSARSLL                                 
              130       140                                        

>>XP_006714172 (OMIM: 612535) PREDICTED: THAP domain-con  (172 aa)
 initn: 967 init1: 967 opt: 967  Z-score: 1069.6  bits: 204.7 E(85289): 7.8e-53
Smith-Waterman score: 967; 100.0% identity (100.0% similar) in 138 aa overlap (1-138:1-138)

               10        20        30        40        50        60
pF1KE0 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 HLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
       ::::::::::::::::::                                          
XP_006 HLVGASSCIEEFQSQFIFISMFKRKCLFKAKNYFSVTIIANIYKVPIFIQST        
              130       140       150       160       170          

>>NP_001304720 (OMIM: 612535) THAP domain-containing pro  (180 aa)
 initn: 1231 init1: 679 opt: 679  Z-score: 754.7  bits: 146.5 E(85289): 2.7e-35
Smith-Waterman score: 1151; 81.1% identity (81.1% similar) in 222 aa overlap (1-222:1-180)

               10        20        30        40        50        60
pF1KE0 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
       ::::::::::::::::::::::::::::::::::::                        
NP_001 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQ------------------------
               70        80        90                              

              130       140       150       160       170       180
pF1KE0 HLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
                         ::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------EHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
                          100       110       120       130        

              190       200       210       220  
pF1KE0 KSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 KSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS
      140       150       160       170       180

>>XP_016863289 (OMIM: 612535) PREDICTED: THAP domain-con  (180 aa)
 initn: 1231 init1: 679 opt: 679  Z-score: 754.7  bits: 146.5 E(85289): 2.7e-35
Smith-Waterman score: 1151; 81.1% identity (81.1% similar) in 222 aa overlap (1-222:1-180)

               10        20        30        40        50        60
pF1KE0 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQGKREKLHCRKNFTLKTVPATNYNH
       ::::::::::::::::::::::::::::::::::::                        
XP_016 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHLQ------------------------
               70        80        90                              

              130       140       150       160       170       180
pF1KE0 HLVGASSCIEEFQSQFIFEHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
                         ::::::::::::::::::::::::::::::::::::::::::
XP_016 ------------------EHSYSVMDSPKKLKHKLDHVIGELEDTKESLRNVLDREKRFQ
                          100       110       120       130        

              190       200       210       220  
pF1KE0 KSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS
       ::::::::::::::::::::::::::::::::::::::::::
XP_016 KSLRKTIRELKDECLISQETANRLDTFCWDCCQESIEQDYIS
      140       150       160       170       180

>>NP_078948 (OMIM: 612537) DNA transposase THAP9 isoform  (903 aa)
 initn: 284 init1: 284 opt: 310  Z-score: 340.7  bits: 72.2 E(85289): 3.1e-12
Smith-Waterman score: 333; 32.3% identity (59.9% similar) in 217 aa overlap (1-210:1-198)

               10        20        30        40        50        60
pF1KE0 MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDV
       :.. :::.::..:    :. .::.:: ::::   . ::. :..:.:  .  :: :  : .
NP_078 MTRSCSAVGCSTRDTVLSRERGLSFHQFPTDTIQRSKWIRAVNRVDPRSKKIWIPGPGAI
               10        20        30        40        50        60

               70        80        90        100       110         
pF1KE0 LCSRHFKKTDFDRSAPNIKLKPGVIPSIFDSPYHL-QGKREKLHCRKNFTLKTVPATNYN
       :::.::...::.  .   ::: :..::.  : :.. :: . : . :...  . .: ..  
NP_078 LCSKHFQESDFESYGIRRKLKKGAVPSV--SLYKIPQGVHLKGKARQKILKQPLPDNS--
               70        80          90       100       110        

     120       130       140       150        160       170        
pF1KE0 HHLVGASSCIEEFQSQFIFEHSYSVMDSPKKL-KHKLDHVIGELEDTKESLRNVLD-REK
                 .:  ..   .:.:: . .:  .  .:: .:   :. .:. : .: . :  
NP_078 ----------QEVATE---DHNYS-LKTPLTIGAEKLAEVQQMLQVSKKRLISVKNYRMI
                  120           130       140       150       160  

       180       190       200           210       220             
pF1KE0 RFQKSLRKTIRELKDECLISQETA----NRLDTFCWDCCQESIEQDYIS           
       . .:.::  :  : .: :.:.::      ... : :.                       
NP_078 KKRKGLR-LIDALVEEKLLSEETECLLRAQFSDFKWELYNWRETDEYSAEMKQFACTLYL
             170       180       190       200       210       220 

NP_078 CSSKVYDYVRKILKLPHSSILRTWLSKCQPSPGFNSNIFSFLQRRVENGDQLYQYCSLLI
             230       240       250       260       270       280 




222 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 06:53:20 2016 done: Thu Nov  3 06:53:21 2016
 Total Scan time:  6.300 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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