Result of FASTA (omim) for pF1KB7230
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7230, 351 aa
  1>>>pF1KB7230 351 - 351 aa - 351 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0991+/-0.000513; mu= 17.8037+/- 0.032
 mean_var=110.3706+/-27.729, 0's: 0 Z-trim(109.5): 565  B-trim: 2073 in 2/49
 Lambda= 0.122081
 statistics sampled from 16952 (17752) to 16952 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.544), E-opt: 0.2 (0.208), width:  16
 Scan time:  6.790

The best scores are:                                      opt bits E(85289)
NP_001028252 (OMIM: 604849) trace amine-associated ( 351) 2393 433.1 4.5e-121
NP_055441 (OMIM: 604849) trace amine-associated re ( 306) 2092 380.0 3.8e-105
NP_003958 (OMIM: 607405) trace amine-associated re ( 337)  973 183.0 8.5e-46
NP_778237 (OMIM: 608923) trace amine-associated re ( 345)  894 169.1 1.3e-41
NP_778227 (OMIM: 608282) trace amine-associated re ( 348)  886 167.7 3.5e-41
NP_444508 (OMIM: 606927) trace amine-associated re ( 342)  851 161.5 2.5e-39
NP_612200 (OMIM: 609333) trace amine-associated re ( 339)  755 144.6 3.1e-34
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359)  519 103.0   1e-21
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362)  519 103.0   1e-21
NP_001124527 (OMIM: 142703) histamine H2 receptor  ( 397)  519 103.1 1.1e-21
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422)  519 103.1 1.1e-21
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422)  519 103.1 1.1e-21
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422)  519 103.1 1.1e-21
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422)  519 103.1 1.1e-21
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422)  519 103.1 1.1e-21
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389)  420 85.6 1.9e-16
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392)  420 85.6 1.9e-16
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397)  420 85.6   2e-16
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400)  420 85.7   2e-16
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403)  420 85.7   2e-16
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406)  420 85.7   2e-16
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414)  420 85.7   2e-16
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418)  420 85.7   2e-16
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420)  420 85.7   2e-16
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446)  420 85.7 2.1e-16
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493)  420 85.8 2.2e-16
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493)  420 85.8 2.2e-16
NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319)  375 77.6 4.2e-14
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388)  374 77.5 5.3e-14
XP_011518927 (OMIM: 602927) PREDICTED: probable G- ( 415)  373 77.4 6.3e-14
XP_016874705 (OMIM: 602927) PREDICTED: probable G- ( 415)  373 77.4 6.3e-14
XP_016874702 (OMIM: 602927) PREDICTED: probable G- ( 434)  373 77.4 6.4e-14
XP_016874703 (OMIM: 602927) PREDICTED: probable G- ( 434)  373 77.4 6.4e-14
XP_016874701 (OMIM: 602927) PREDICTED: probable G- ( 434)  373 77.4 6.4e-14
XP_011518925 (OMIM: 602927) PREDICTED: probable G- ( 434)  373 77.4 6.4e-14
XP_016874704 (OMIM: 602927) PREDICTED: probable G- ( 434)  373 77.4 6.4e-14
XP_011518926 (OMIM: 602927) PREDICTED: probable G- ( 434)  373 77.4 6.4e-14
NP_006134 (OMIM: 602927) probable G-protein couple ( 415)  372 77.2 7.1e-14
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391)  368 76.5 1.1e-13
NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292)  366 76.0 1.2e-13
XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300)  366 76.0 1.2e-13
NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300)  366 76.0 1.2e-13
NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300)  366 76.0 1.2e-13
NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300)  366 76.0 1.2e-13
NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314)  366 76.0 1.2e-13
XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  366 76.1 1.3e-13
XP_016866394 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  366 76.1 1.3e-13
XP_016866393 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  366 76.1 1.3e-13
XP_011534155 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  366 76.1 1.3e-13
XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  366 76.1 1.3e-13


>>NP_001028252 (OMIM: 604849) trace amine-associated rec  (351 aa)
 initn: 2393 init1: 2393 opt: 2393  Z-score: 2294.6  bits: 433.1 E(85289): 4.5e-121
Smith-Waterman score: 2393; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351)

               10        20        30        40        50        60
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 HAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDAL
              250       260       270       280       290       300

              310       320       330       340       350 
pF1KB7 TWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
              310       320       330       340       350 

>>NP_055441 (OMIM: 604849) trace amine-associated recept  (306 aa)
 initn: 2092 init1: 2092 opt: 2092  Z-score: 2008.8  bits: 380.0 E(85289): 3.8e-105
Smith-Waterman score: 2092; 100.0% identity (100.0% similar) in 306 aa overlap (46-351:1-306)

          20        30        40        50        60        70     
pF1KB7 TQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLH
                                     ::::::::::::::::::::::::::::::
NP_055                               MYSFMAGSIFITIFGNLAMIISISYFKQLH
                                             10        20        30

          80        90       100       110       120       130     
pF1KB7 TPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLC
               40        50        60        70        80        90

         140       150       160       170       180       190     
pF1KB7 SVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILV
              100       110       120       130       140       150

         200       210       220       230       240       250     
pF1KB7 ACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQVK
              160       170       180       190       200       210

         260       270       280       290       300       310     
pF1KB7 KDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIY
              220       230       240       250       260       270

         320       330       340       350 
pF1KB7 GFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
       ::::::::::::::::::::::::::::::::::::
NP_055 GFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
              280       290       300      

>>NP_003958 (OMIM: 607405) trace amine-associated recept  (337 aa)
 initn: 976 init1: 566 opt: 973  Z-score: 943.2  bits: 183.0 E(85289): 8.5e-46
Smith-Waterman score: 973; 43.3% identity (75.6% similar) in 307 aa overlap (30-336:21-326)

               10        20        30        40        50        60
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
                                    : :::.. ..::.....:   :....: ..:
NP_003          MRAVFIQGAEEHPAAFCYQVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLG
                        10        20        30        40        50 

               70        80        90       100       110       120
pF1KB7 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
       :. . ...:::: ::::::::.::.:..:..::. ..: : :::::.::.::  .:... 
NP_003 NVFVAFAVSYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHT
              60        70        80        90       100       110 

              130       140       150       160       170       180
pF1KB7 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
        .: .. .::::::: ..:::  ::: :::: .:.:. :  : .:  :.::.:..   ..
NP_003 YLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLY
             120       130       140       150       160       170 

              190       200       210       220       230       240
pF1KB7 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
       ...    .  .   . : .:: ...::.::   :   ::.:  .:...: :::.:. ..:
NP_003 TDVVETRLSQWLEEMPCVGSCQLLLNKFWGWLNF-PLFFVPCLIMISLYVKIFVVATRQA
             180       190       200        210       220       230

              250       260       270       280       290       300
pF1KB7 HAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDAL
       . :..: ..  . .:...::::::::..:..::::.:  .  ..: .:.: :: ..:: .
NP_003 QQITTLSKSLAGAAKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIF
              240       250       260       270       280       290

              310       320       330       340       350 
pF1KB7 TWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
        ::.::::.:::.:: : : :::.:::  :  :.::               
NP_003 IWFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE    
              300       310       320       330           

>>NP_778237 (OMIM: 608923) trace amine-associated recept  (345 aa)
 initn: 867 init1: 500 opt: 894  Z-score: 867.9  bits: 169.1 E(85289): 1.3e-41
Smith-Waterman score: 894; 39.6% identity (70.1% similar) in 321 aa overlap (25-337:14-333)

               10        20        30        40        50        60
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
                               :    : :: .   : : :: .:  .. .  ...::
NP_778            MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFG
                          10        20        30        40         

               70        80        90       100       110       120
pF1KB7 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
       :: ..::: .:::::.:::::. :.: .:::.: :.::.::.:.::.::::: .:: .. 
NP_778 NLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHT
      50        60        70        80        90       100         

              130       140       150       160       170       180
pF1KB7 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
         :. .  .:.:::: ..:::. :.  ::.: ::.:. :    . . : .:  .. .: .
NP_778 CCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFY
     110       120       130       140       150       160         

              190       200       210       220       230       240
pF1KB7 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
       . .: ::.:  .  . : ..: .. :. :  : :.. :: :  .:. .::.:: :.:..:
NP_778 TGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLS-FFIPTFIMIILYGNIFLVARRQA
     170       180       190       200        210       220        

                     250        260       270       280       290  
pF1KB7 HAINNL-------RENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFST
       . :.:         :. . .: ....:::::::... .:.. :.:  .  :.: :..: :
NP_778 KKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFIT
      230       240       250       260       270       280        

            300       310       320       330       340       350 
pF1KB7 PVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
       :. ...   : .:.::. :::::..::::::.:.: :. :.....              
NP_778 PACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI  
      290       300       310       320       330       340       

>>NP_778227 (OMIM: 608282) trace amine-associated recept  (348 aa)
 initn: 882 init1: 551 opt: 886  Z-score: 860.2  bits: 167.7 E(85289): 3.5e-41
Smith-Waterman score: 886; 40.2% identity (70.1% similar) in 321 aa overlap (25-337:14-333)

               10        20        30        40        50        60
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
                               : .  :.:: ..  : : :  .:. .. .  .. ::
NP_778            MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFG
                          10        20        30        40         

               70        80        90       100       110       120
pF1KB7 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
       :: ..:.: .:::::::::::: :.: .:::.: :.::.: .::::.::::: ..::.. 
NP_778 NLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHT
      50        60        70        80        90       100         

              130       140       150       160       170       180
pF1KB7 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
        ::  . ..:.:::: ...::. :.  :: : ::.:. :    ..: :    ...:.. .
NP_778 CFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFY
     110       120       130       140       150       160         

              190       200       210       220       230       240
pF1KB7 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
       . :  .:::   . ..: ..: . .:. :    :.  :: :.  :: ::.::: :....:
NP_778 TGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL-FFIPNVAMVFIYSKIFLVAKHQA
     170       180       190       200        210       220        

                     250        260       270       280       290  
pF1KB7 HAINNL-------RENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFST
       . :..         :. ...: :...::::::::....::. :.: .   ..: ..:: :
NP_778 RKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFIT
      230       240       250       260       270       280        

            300       310       320       330       340       350  
pF1KB7 PVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE 
       :  ... :.:  :.::. :::::.::: :: .:.: :. ::.. .               
NP_778 PPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
      290       300       310       320       330       340        

>>NP_444508 (OMIM: 606927) trace amine-associated recept  (342 aa)
 initn: 846 init1: 516 opt: 851  Z-score: 827.0  bits: 161.5 E(85289): 2.5e-39
Smith-Waterman score: 851; 38.5% identity (68.6% similar) in 322 aa overlap (25-337:13-332)

               10        20        30        40         50         
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYS-FMAGSIFITIF
                               : :  : :: :.  : : :: .:. :  ::. ...:
NP_444             MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSL-LAVF
                           10        20        30        40        

      60        70        80        90       100       110         
pF1KB7 GNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIY
       ::: .. :. .:::::.:::::: :.: .:::.: :.: .::.:.::.:::::  :: ..
NP_444 GNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLH
        50        60        70        80        90       100       

     120       130       140       150       160       170         
pF1KB7 YSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVV
          :. .  .:..::: . :::. ..  ::.:.::.:. :    . . : .: ... .: 
NP_444 SCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVF
       110       120       130       140       150       160       

     180       190       200       210       220       230         
pF1KB7 FSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKH
       .. .  ::.:     . : ..: .. .. :    :.  :: :  .:. .:.::: .....
NP_444 YTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQ
       170       180       190       200        210       220      

     240              250        260       270       280       290 
pF1KB7 A-------HAINNLRENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFS
       :         ...  :. . .: :...:::::::... .:.. :.:    ::.: :..: 
NP_444 AIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFL
        230       240       250       260       270       280      

             300       310       320       330       340       350 
pF1KB7 TPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
       ::. ...   : .:.::. :::::..::::::.:.: :: : ....              
NP_444 TPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE    
        290       300       310       320       330       340      

>>NP_612200 (OMIM: 609333) trace amine-associated recept  (339 aa)
 initn: 1065 init1: 610 opt: 755  Z-score: 735.7  bits: 144.6 E(85289): 3.1e-34
Smith-Waterman score: 1111; 50.6% identity (76.7% similar) in 322 aa overlap (25-335:5-324)

               10        20        30        40        50        60
pF1KB7 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
                               : .  : :: .:. :  ::...::.:.  :. :. :
NP_612                     MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVG
                                   10        20        30        40

               70        80        90       100       110       120
pF1KB7 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
       :: .:.:::.:::::::::.:: ::: .:::::  .:::::.::.:.::::: .::::. 
NP_612 NLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHT
               50        60        70        80        90       100

              130       140       150       160       170       180
pF1KB7 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
       : :.::: .:::::  ..:::.::.: :: :..:..: ::  .... ::::..::::..:
NP_612 STDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIF
              110       120       130       140       150       160

              190        200       210       220       230         
pF1KB7 SEAYADGIEG-YDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKH
        :    : :  :   : : ..: :.:.:. :.  ::..:. :::.:. .: .:. .....
NP_612 LELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQ
              170       180       190       200       210       220

     240       250                 260       270       280         
pF1KB7 AHAINNLRENQNNQV----------KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLN
       :. :..   ::. :.          .:..::.::::::.::::.:: : :.  ..::::.
NP_612 ARLISD--ANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLH
                230       240       250       260       270        

     290       300       310       320       330       340         
pF1KB7 FSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKE
       .  : .: :.: ::::.::: ::..:.:::::::.:::..:.::::              
NP_612 YIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELS
      280       290       300       310       320       330        

     350 
pF1KB7 SE
         
NP_612 S 
         

>>NP_071640 (OMIM: 142703) histamine H2 receptor isoform  (359 aa)
 initn: 416 init1: 272 opt: 519  Z-score: 510.8  bits: 103.0 E(85289): 1e-21
Smith-Waterman score: 519; 30.5% identity (63.3% similar) in 311 aa overlap (39-344:14-317)

       10        20        30        40        50        60        
pF1KB7 ELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISI
                                     : . ....   .:  :.::. ::... ...
NP_071                  MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAV
                                10        20        30        40   

       70        80        90       100       110       120        
pF1KB7 SYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSI
       .  ..:.. :: .:.:.::::.:::. ..:.: : ..   : :: .::.:: :.:.::  
NP_071 GLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCT
            50        60        70        80        90       100   

      130       140       150        160       170       180       
pF1KB7 TSIFHLCSVAIDRFYAICYPLLYSTKITIPV-IKRLLLLCWSVPGAFAFGVVFS--EAYA
       .::..:  ...::. :.  :: : . .: :: .   :.: : .  ...:  .    ..  
NP_071 ASILNLFMISLDRYCAVMDPLRYPVLVT-PVRVAISLVLIWVISITLSFLSIHLGWNSRN
           110       120       130        140       150       160  

         190       200       210       220       230       240     
pF1KB7 DGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINN
       .  .:       .:.: :. :...: .  .. :. :  .:   : .:: :.: .:. ::.
NP_071 ETSKGNHT----TSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINH
            170           180       190       200       210        

         250       260       270       280       290         300   
pF1KB7 LRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPV--VLFDALTWF
       .   .   .. ..::. ::. :.:.:..:::: .:: ..   :  .  .  ::   . :.
NP_071 ISSWKAATIR-EHKATVTLAAVMGAFIICWFP-YFTAFVYRGLRGDDAINEVLEAIVLWL
      220        230       240        250       260       270      

           310       320       330       340       350             
pF1KB7 GYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE            
       :: ::. ::..:. .   :: . . ..  .. .   :.: :                   
NP_071 GYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQE
        280       290       300       310       320       330      

NP_071 EKPLKLQVWSGTEVTAPQGATDR
        340       350         

>>XP_006714928 (OMIM: 142703) PREDICTED: histamine H2 re  (362 aa)
 initn: 416 init1: 272 opt: 519  Z-score: 510.7  bits: 103.0 E(85289): 1e-21
Smith-Waterman score: 519; 30.5% identity (63.3% similar) in 311 aa overlap (39-344:14-317)

       10        20        30        40        50        60        
pF1KB7 ELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISI
                                     : . ....   .:  :.::. ::... ...
XP_006                  MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAV
                                10        20        30        40   

       70        80        90       100       110       120        
pF1KB7 SYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSI
       .  ..:.. :: .:.:.::::.:::. ..:.: : ..   : :: .::.:: :.:.::  
XP_006 GLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCT
            50        60        70        80        90       100   

      130       140       150        160       170       180       
pF1KB7 TSIFHLCSVAIDRFYAICYPLLYSTKITIPV-IKRLLLLCWSVPGAFAFGVVFS--EAYA
       .::..:  ...::. :.  :: : . .: :: .   :.: : .  ...:  .    ..  
XP_006 ASILNLFMISLDRYCAVMDPLRYPVLVT-PVRVAISLVLIWVISITLSFLSIHLGWNSRN
           110       120       130        140       150       160  

         190       200       210       220       230       240     
pF1KB7 DGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINN
       .  .:       .:.: :. :...: .  .. :. :  .:   : .:: :.: .:. ::.
XP_006 ETSKGNHT----TSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINH
            170           180       190       200       210        

         250       260       270       280       290         300   
pF1KB7 LRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPV--VLFDALTWF
       .   .   .. ..::. ::. :.:.:..:::: .:: ..   :  .  .  ::   . :.
XP_006 ISSWKAATIR-EHKATVTLAAVMGAFIICWFP-YFTAFVYRGLRGDDAINEVLEAIVLWL
      220        230       240        250       260       270      

           310       320       330       340       350             
pF1KB7 GYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE            
       :: ::. ::..:. .   :: . . ..  .. .   :.: :                   
XP_006 GYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQE
        280       290       300       310       320       330      

XP_006 EKPLKLQVWSGTEVTAPQGATDRNSS
        340       350       360  

>>NP_001124527 (OMIM: 142703) histamine H2 receptor isof  (397 aa)
 initn: 416 init1: 272 opt: 519  Z-score: 510.3  bits: 103.1 E(85289): 1.1e-21
Smith-Waterman score: 519; 30.5% identity (63.3% similar) in 311 aa overlap (39-344:14-317)

       10        20        30        40        50        60        
pF1KB7 ELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISI
                                     : . ....   .:  :.::. ::... ...
NP_001                  MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAV
                                10        20        30        40   

       70        80        90       100       110       120        
pF1KB7 SYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSI
       .  ..:.. :: .:.:.::::.:::. ..:.: : ..   : :: .::.:: :.:.::  
NP_001 GLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCT
            50        60        70        80        90       100   

      130       140       150        160       170       180       
pF1KB7 TSIFHLCSVAIDRFYAICYPLLYSTKITIPV-IKRLLLLCWSVPGAFAFGVVFS--EAYA
       .::..:  ...::. :.  :: : . .: :: .   :.: : .  ...:  .    ..  
NP_001 ASILNLFMISLDRYCAVMDPLRYPVLVT-PVRVAISLVLIWVISITLSFLSIHLGWNSRN
           110       120       130        140       150       160  

         190       200       210       220       230       240     
pF1KB7 DGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINN
       .  .:       .:.: :. :...: .  .. :. :  .:   : .:: :.: .:. ::.
NP_001 ETSKGNHT----TSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINH
            170           180       190       200       210        

         250       260       270       280       290         300   
pF1KB7 LRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPV--VLFDALTWF
       .   .   .. ..::. ::. :.:.:..:::: .:: ..   :  .  .  ::   . :.
NP_001 ISSWKAATIR-EHKATVTLAAVMGAFIICWFP-YFTAFVYRGLRGDDAINEVLEAIVLWL
      220        230       240        250       260       270      

           310       320       330       340       350             
pF1KB7 GYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE            
       :: ::. ::..:. .   :: . . ..  .. .   :.: :                   
NP_001 GYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQE
        280       290       300       310       320       330      

NP_001 EKPLKLQVWSGTEVTAPQGATDRPWLCLPECWSVELTHSFIHLFIHSFANIHPIPTTCQE
        340       350       360       370       380       390      




351 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:23:45 2016 done: Fri Nov  4 20:23:46 2016
 Total Scan time:  6.790 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com