Result of FASTA (omim) for pF1KB6586
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6586, 406 aa
  1>>>pF1KB6586 406 - 406 aa - 406 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7949+/-0.000436; mu= 14.4344+/- 0.027
 mean_var=67.2589+/-13.311, 0's: 0 Z-trim(109.9): 134  B-trim: 277 in 2/50
 Lambda= 0.156387
 statistics sampled from 18006 (18145) to 18006 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.573), E-opt: 0.2 (0.213), width:  16
 Scan time:  8.570

The best scores are:                                      opt bits E(85289)
NP_000615 (OMIM: 601841) plasma serine protease in ( 406) 2610 598.2 1.2e-170
NP_006206 (OMIM: 147935) kallistatin isoform 2 pre ( 427) 1139 266.3   1e-70
NP_001275962 (OMIM: 147935) kallistatin isoform 2  ( 427) 1139 266.3   1e-70
NP_001275961 (OMIM: 147935) kallistatin isoform 1  ( 464) 1139 266.3 1.1e-70
XP_011535017 (OMIM: 615677) PREDICTED: serpin A9 i ( 417) 1122 262.4 1.4e-69
XP_011535016 (OMIM: 615677) PREDICTED: serpin A9 i ( 417) 1122 262.4 1.4e-69
NP_783866 (OMIM: 615677) serpin A9 isoform A [Homo ( 435) 1122 262.4 1.5e-69
NP_001076 (OMIM: 107280) alpha-1-antichymotrypsin  ( 423) 1111 260.0 8.2e-69
NP_001271204 (OMIM: 615677) serpin A9 isoform C [H ( 399) 1079 252.7 1.2e-66
NP_001121179 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1053 246.9   7e-65
NP_001002236 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1053 246.9   7e-65
NP_001121176 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1053 246.9   7e-65
NP_000286 (OMIM: 107400,606963,613490) alpha-1-ant ( 418) 1053 246.9   7e-65
NP_001121174 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1053 246.9   7e-65
NP_001121178 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1053 246.9   7e-65
XP_016876859 (OMIM: 107400,606963,613490) PREDICTE ( 418) 1053 246.9   7e-65
NP_001121175 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1053 246.9   7e-65
NP_001002235 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1053 246.9   7e-65
NP_001121173 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1053 246.9   7e-65
NP_001121172 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1053 246.9   7e-65
NP_001121177 (OMIM: 107400,606963,613490) alpha-1- ( 418) 1053 246.9   7e-65
NP_001747 (OMIM: 122500,611489) corticosteroid-bin ( 405) 1026 240.8 4.7e-63
XP_011535018 (OMIM: 615677) PREDICTED: serpin A9 i ( 337)  984 231.3 2.8e-60
XP_011535019 (OMIM: 615677) PREDICTED: serpin A9 i ( 337)  984 231.3 2.8e-60
NP_000345 (OMIM: 300932,314200) thyroxine-binding  ( 415)  954 224.5 3.7e-58
NP_006211 (OMIM: 107410) putative alpha-1-antitryp ( 421)  927 218.4 2.6e-56
XP_005262237 (OMIM: 300932,314200) PREDICTED: thyr ( 371)  865 204.4 3.7e-52
XP_006724746 (OMIM: 300932,314200) PREDICTED: thyr ( 425)  856 202.4 1.7e-51
NP_001271205 (OMIM: 615677) serpin A9 isoform D [H ( 286)  823 194.9 2.1e-49
NP_001035983 (OMIM: 615677) serpin A9 isoform B [H ( 335)  735 175.1 2.3e-43
XP_005267790 (OMIM: 605271) PREDICTED: protein Z-d ( 444)  668 160.0   1e-38
NP_057270 (OMIM: 605271) protein Z-dependent prote ( 444)  668 160.0   1e-38
NP_001094077 (OMIM: 605271) protein Z-dependent pr ( 444)  668 160.0   1e-38
XP_016876842 (OMIM: 605271) PREDICTED: protein Z-d ( 484)  668 160.0 1.1e-38
XP_011512976 (OMIM: 173321,613453) PREDICTED: serp ( 376)  663 158.9   2e-38
NP_004559 (OMIM: 173321,613453) serpin B6 isoform  ( 376)  663 158.9   2e-38
NP_001258753 (OMIM: 173321,613453) serpin B6 isofo ( 376)  663 158.9   2e-38
XP_011512975 (OMIM: 173321,613453) PREDICTED: serp ( 376)  663 158.9   2e-38
NP_001284629 (OMIM: 173321,613453) serpin B6 isofo ( 376)  663 158.9   2e-38
NP_001284628 (OMIM: 173321,613453) serpin B6 isofo ( 376)  663 158.9   2e-38
NP_001258754 (OMIM: 173321,613453) serpin B6 isofo ( 376)  663 158.9   2e-38
XP_016866429 (OMIM: 173321,613453) PREDICTED: serp ( 380)  663 158.9   2e-38
NP_001182220 (OMIM: 173321,613453) serpin B6 isofo ( 380)  663 158.9   2e-38
NP_001258751 (OMIM: 173321,613453) serpin B6 isofo ( 390)  663 158.9   2e-38
NP_001258752 (OMIM: 173321,613453) serpin B6 isofo ( 395)  663 158.9 2.1e-38
XP_011512974 (OMIM: 173321,613453) PREDICTED: serp ( 454)  663 158.9 2.3e-38
NP_004146 (OMIM: 601799) serpin B9 [Homo sapiens]  ( 376)  661 158.4 2.7e-38
XP_005249241 (OMIM: 601799) PREDICTED: serpin B9 i ( 376)  661 158.4 2.7e-38
NP_942130 (OMIM: 601697,617115) serpin B8 isoform  ( 374)  649 155.7 1.7e-37
NP_002631 (OMIM: 601697,617115) serpin B8 isoform  ( 374)  649 155.7 1.7e-37


>>NP_000615 (OMIM: 601841) plasma serine protease inhibi  (406 aa)
 initn: 2610 init1: 2610 opt: 2610  Z-score: 3184.5  bits: 598.2 E(85289): 1.2e-170
Smith-Waterman score: 2610; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406)

               10        20        30        40        50        60
pF1KB6 MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALASAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALASAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 PSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELNQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 PRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 KGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSRED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSRED
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 LYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGT
              310       320       330       340       350       360

              370       380       390       400      
pF1KB6 RAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNILFLGKVNRP
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNILFLGKVNRP
              370       380       390       400      

>>NP_006206 (OMIM: 147935) kallistatin isoform 2 precurs  (427 aa)
 initn: 984 init1: 625 opt: 1139  Z-score: 1390.5  bits: 266.3 E(85289): 1e-70
Smith-Waterman score: 1139; 45.0% identity (74.8% similar) in 420 aa overlap (4-406:6-424)

                 10         20             30           40         
pF1KB6   MQLFLLLCLV-LLSPQGASLHRHHPREM-----KKRVEDLHVGAT---VAPSSRRDFT
            .::: :: ::. . ..:: .:  :      .... .   :.    .::..  ::.
NP_006 MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANA-DFA
               10        20        30        40        50          

      50        60        70        80        90       100         
pF1KB6 FDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHR
       : .:  .:: .:...:::::.::: . ::::::: : .. :::::::.:: . ::...::
NP_006 FRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHR
      60        70        80        90       100       110         

     110       120       130       140       150       160         
pF1KB6 GFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAM
       :::.::. :: :  :..  .:.::: .  . .   :..   ..: :  : ::: :..:..
NP_006 GFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTI
     120       130       140       150       160       170         

     170       180       190       200       210       220         
pF1KB6 KQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSET
       . :::.: :.:.::::::...: .......::::.::: ::  :  . :  .::::  .:
NP_006 QLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENT
     180       190       200       210       220       230         

     230       240        250       260       270       280        
pF1KB6 VVRVPMMSREDQYH-YLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLR
       .:::::: .....: :: :: : : :. . :.:.::..::::..:::...:. :. . : 
NP_006 TVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLM
     240       250       260       270       280       290         

      290           300       310       320       330       340    
pF1KB6 KWLKMFKKR----QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQV
       .: ....::    .:::.:::::: ::: :...:: ::....:.. ::::::........
NP_006 RWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEA
     300       310       320       330       340       350         

          350       360       370       380       390          400 
pF1KB6 SEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNN---ILFLG
       :.  :::...:::.::.:::::.  . : ::. : . : ::::::. : ...   .::::
NP_006 SKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLG
     360       370       380       390       400       410         

               
pF1KB6 KVNRP   
       ::  :   
NP_006 KVVDPTKP
     420       

>>NP_001275962 (OMIM: 147935) kallistatin isoform 2 prec  (427 aa)
 initn: 984 init1: 625 opt: 1139  Z-score: 1390.5  bits: 266.3 E(85289): 1e-70
Smith-Waterman score: 1139; 45.0% identity (74.8% similar) in 420 aa overlap (4-406:6-424)

                 10         20             30           40         
pF1KB6   MQLFLLLCLV-LLSPQGASLHRHHPREM-----KKRVEDLHVGAT---VAPSSRRDFT
            .::: :: ::. . ..:: .:  :      .... .   :.    .::..  ::.
NP_001 MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANA-DFA
               10        20        30        40        50          

      50        60        70        80        90       100         
pF1KB6 FDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHR
       : .:  .:: .:...:::::.::: . ::::::: : .. :::::::.:: . ::...::
NP_001 FRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHR
      60        70        80        90       100       110         

     110       120       130       140       150       160         
pF1KB6 GFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAM
       :::.::. :: :  :..  .:.::: .  . .   :..   ..: :  : ::: :..:..
NP_001 GFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTI
     120       130       140       150       160       170         

     170       180       190       200       210       220         
pF1KB6 KQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSET
       . :::.: :.:.::::::...: .......::::.::: ::  :  . :  .::::  .:
NP_001 QLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENT
     180       190       200       210       220       230         

     230       240        250       260       270       280        
pF1KB6 VVRVPMMSREDQYH-YLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLR
       .:::::: .....: :: :: : : :. . :.:.::..::::..:::...:. :. . : 
NP_001 TVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLM
     240       250       260       270       280       290         

      290           300       310       320       330       340    
pF1KB6 KWLKMFKKR----QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQV
       .: ....::    .:::.:::::: ::: :...:: ::....:.. ::::::........
NP_001 RWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEA
     300       310       320       330       340       350         

          350       360       370       380       390          400 
pF1KB6 SEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNN---ILFLG
       :.  :::...:::.::.:::::.  . : ::. : . : ::::::. : ...   .::::
NP_001 SKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLG
     360       370       380       390       400       410         

               
pF1KB6 KVNRP   
       ::  :   
NP_001 KVVDPTKP
     420       

>>NP_001275961 (OMIM: 147935) kallistatin isoform 1 [Hom  (464 aa)
 initn: 984 init1: 625 opt: 1139  Z-score: 1389.9  bits: 266.3 E(85289): 1.1e-70
Smith-Waterman score: 1139; 45.0% identity (74.8% similar) in 420 aa overlap (4-406:43-461)

                                          10         20            
pF1KB6                            MQLFLLLCLV-LLSPQGASLHRHHPREM-----
                                     .::: :: ::. . ..:: .:  :      
NP_001 HSWYRAALTEGQGLLAANPGLRVQRMHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSS
             20        30        40        50        60        70  

        30           40        50        60        70        80    
pF1KB6 KKRVEDLHVGAT---VAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAG
       .... .   :.    .::..  ::.: .:  .:: .:...:::::.::: . ::::::: 
NP_001 HQQILETGEGSPSLKIAPANA-DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGAC
             80        90        100       110       120       130 

           90       100       110       120       130       140    
pF1KB6 SSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDT
       : .. :::::::.:: . ::...:::::.::. :: :  :..  .:.::: .  . .   
NP_001 SHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAK
             140       150       160       170       180       190 

          150       160       170       180       190       200    
pF1KB6 FVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIF
       :..   ..: :  : ::: :..:... :::.: :.:.::::::...: .......::::.
NP_001 FLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIY
             200       210       220       230       240       250 

          210       220       230       240        250       260   
pF1KB6 FKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYH-YLLDRNLSCRVVGVPYQGNA
       ::: ::  :  . :  .::::  .:.:::::: .....: :: :: : : :. . :.:.:
NP_001 FKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA
             260       270       280       290       300       310 

           270       280       290           300       310         
pF1KB6 TALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR----QLELYLPKFSIEGSYQLEKVLP
       :..::::..:::...:. :. . : .: ....::    .:::.:::::: ::: :...::
NP_001 TVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILP
             320       330       340       350       360       370 

     320       330       340       350       360       370         
pF1KB6 SLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNS
        ::....:.. ::::::........:.  :::...:::.::.:::::.  . : ::. : 
NP_001 RLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNR
             380       390       400       410       420       430 

     380       390          400         
pF1KB6 QRLVFNRPFLMFIVDNN---ILFLGKVNRP   
       . : ::::::. : ...   .::::::  :   
NP_001 HILRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP
             440       450       460    

>>XP_011535017 (OMIM: 615677) PREDICTED: serpin A9 isofo  (417 aa)
 initn: 1118 init1: 550 opt: 1122  Z-score: 1369.9  bits: 262.4 E(85289): 1.4e-69
Smith-Waterman score: 1122; 45.2% identity (75.8% similar) in 405 aa overlap (7-406:14-414)

                      10        20        30        40        50   
pF1KB6        MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRRDFTFDLY
                    ::  .   . :.    .::  . .     . :. . :   ::.: ::
XP_011 MASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTK----STPASQVYSLNTDFAFRLY
               10        20        30            40        50      

            60        70        80        90       100       110   
pF1KB6 RALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQ
       : :.  .:::.:::::::.: ::::::::: : :: :::.:::.:: .. :. .:.:::.
XP_011 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH
         60        70        80        90       100       110      

           120       130       140       150       160       170   
pF1KB6 LLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQIN
       :.. :. :   . :..:.:::.   ..:: .:.. .: :: :..: :.: . . :. .::
XP_011 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN
        120       130       140       150       160       170      

           180       190       200       210       220        230  
pF1KB6 DYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQ-DFYVTSETVVR
       ..: :.:.::.::....::  .....::.::::::::  :. . :...  : :  ...:.
XP_011 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH
        180       190       200       210       220       230      

            240       250       260       270       280       290  
pF1KB6 VPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLK
       :::: ...:. . .: .:.: :. . :.:.:.:.:.:::.:::.:.:..:: .::::: .
XP_011 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH
        240       250       260       270       280       290      

            300       310       320       330       340       350  
pF1KB6 MFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAV
        ..:: .:...:.::: .::.:: .::..::.::: ..::.:::......:::. .::::
XP_011 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV
        300       310       320       330       340       350      

            360       370       380        390          400        
pF1KB6 VEVDESGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVD---NNILFLGKVNRP  
       ..:.: ::.:.::: : :  ::    :   : ::: :::.:..   ..:::::::. :  
XP_011 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK
        360       370       380       390       400       410      

XP_011 S
        

>>XP_011535016 (OMIM: 615677) PREDICTED: serpin A9 isofo  (417 aa)
 initn: 1118 init1: 550 opt: 1122  Z-score: 1369.9  bits: 262.4 E(85289): 1.4e-69
Smith-Waterman score: 1122; 45.2% identity (75.8% similar) in 405 aa overlap (7-406:14-414)

                      10        20        30        40        50   
pF1KB6        MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRRDFTFDLY
                    ::  .   . :.    .::  . .     . :. . :   ::.: ::
XP_011 MASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTK----STPASQVYSLNTDFAFRLY
               10        20        30            40        50      

            60        70        80        90       100       110   
pF1KB6 RALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQ
       : :.  .:::.:::::::.: ::::::::: : :: :::.:::.:: .. :. .:.:::.
XP_011 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH
         60        70        80        90       100       110      

           120       130       140       150       160       170   
pF1KB6 LLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQIN
       :.. :. :   . :..:.:::.   ..:: .:.. .: :: :..: :.: . . :. .::
XP_011 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN
        120       130       140       150       160       170      

           180       190       200       210       220        230  
pF1KB6 DYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQ-DFYVTSETVVR
       ..: :.:.::.::....::  .....::.::::::::  :. . :...  : :  ...:.
XP_011 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH
        180       190       200       210       220       230      

            240       250       260       270       280       290  
pF1KB6 VPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLK
       :::: ...:. . .: .:.: :. . :.:.:.:.:.:::.:::.:.:..:: .::::: .
XP_011 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH
        240       250       260       270       280       290      

            300       310       320       330       340       350  
pF1KB6 MFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAV
        ..:: .:...:.::: .::.:: .::..::.::: ..::.:::......:::. .::::
XP_011 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV
        300       310       320       330       340       350      

            360       370       380        390          400        
pF1KB6 VEVDESGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVD---NNILFLGKVNRP  
       ..:.: ::.:.::: : :  ::    :   : ::: :::.:..   ..:::::::. :  
XP_011 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK
        360       370       380       390       400       410      

XP_011 S
        

>>NP_783866 (OMIM: 615677) serpin A9 isoform A [Homo sap  (435 aa)
 initn: 1118 init1: 550 opt: 1122  Z-score: 1369.6  bits: 262.4 E(85289): 1.5e-69
Smith-Waterman score: 1122; 45.2% identity (75.8% similar) in 405 aa overlap (7-406:32-432)

                                       10        20        30      
pF1KB6                         MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHV
                                     ::  .   . :.    .::  . .     .
NP_783 QGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTK----ST
              10        20        30        40        50           

         40        50        60        70        80        90      
pF1KB6 GATVAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLG
        :. . :   ::.: ::: :.  .:::.:::::::.: ::::::::: : :: :::.:::
NP_783 PASQVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLG
        60        70        80        90       100       110       

        100       110       120       130       140       150      
pF1KB6 LNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLAD
       .:: .. :. .:.:::.:.. :. :   . :..:.:::.   ..:: .:.. .: :: :.
NP_783 FNLTHTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAE
       120       130       140       150       160       170       

        160       170       180       190       200       210      
pF1KB6 TFPTNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHK
       .: :.: . . :. .::..: :.:.::.::....::  .....::.::::::::  :. .
NP_783 VFSTDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPE
       180       190       200       210       220       230       

        220        230       240       250       260       270     
pF1KB6 GTQEQ-DFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKM
        :...  : :  ...:.:::: ...:. . .: .:.: :. . :.:.:.:.:.:::.:::
NP_783 YTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKM
       240       250       260       270       280       290       

         280       290       300       310       320       330     
pF1KB6 QQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSG
       .:.:..:: .::::: . ..:: .:...:.::: .::.:: .::..::.::: ..::.::
NP_783 RQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSG
       300       310       320       330       340       350       

         340       350       360       370       380        390    
pF1KB6 ISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVD
       :......:::. .::::..:.: ::.:.::: : :  ::    :   : ::: :::.:..
NP_783 IAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITN
       360       370       380       390       400       410       

             400         
pF1KB6 ---NNILFLGKVNRP   
          ..:::::::. :   
NP_783 KATDGILFLGKVENPTKS
       420       430     

>>NP_001076 (OMIM: 107280) alpha-1-antichymotrypsin prec  (423 aa)
 initn: 1063 init1: 636 opt: 1111  Z-score: 1356.4  bits: 260.0 E(85289): 8.2e-69
Smith-Waterman score: 1111; 47.4% identity (75.9% similar) in 403 aa overlap (10-406:21-420)

                          10        20        30        40         
pF1KB6            MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRRDFT
                           ::  :..   ...  .: . :    ::   .: :.  ::.
NP_001 MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDR--GTHVDLGLA-SANVDFA
               10        20        30        40          50        

      50        60        70        80        90       100         
pF1KB6 FDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHR
       :.::. :.  ::.....:::.::: .::.::::: ..:  .::.:: .:: ..:: :.:.
NP_001 FSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQ
        60        70        80        90       100       110       

     110       120       130       140       150       160         
pF1KB6 GFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAM
       .::.::. :::  : .:::.:::.:.   ..: : :.   : :: ...: :.:.:::.: 
NP_001 SFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAK
       120       130       140       150       160       170       

     170       180       190       200       210       220         
pF1KB6 KQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSET
       : ::::: . :.:::.::.:.:::......:::::::::::  :. . :... ::.... 
NP_001 KLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKK
       180       190       200       210       220       230       

     230       240        250       260       270       280        
pF1KB6 VVRVPMMSRED-QYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLR
        : ::::: .     :. :..::: :: . : :::.::::::.. ::..::  :  .::.
NP_001 WVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLK
       240       250       260       270       280       290       

      290        300       310       320       330       340       
pF1KB6 KWLKMFKKRQL-ELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEM
       .:   .. :.. :::::::::  .:.:. .: .::: ..:::.::::::..  :. ::..
NP_001 RWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQV
       300       310       320       330       340       350       

       350       360       370       380        390          400   
pF1KB6 VHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVDN---NILFLGKV
       :::::..: : ::.:.:::.. .:. :: .... .: :::::::.:: .   ::.:..::
NP_001 VHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKV
       360       370       380       390       400       410       

             
pF1KB6 NRP   
       . :   
NP_001 TNPKQA
       420   

>>NP_001271204 (OMIM: 615677) serpin A9 isoform C [Homo   (399 aa)
 initn: 1077 init1: 511 opt: 1079  Z-score: 1317.8  bits: 252.7 E(85289): 1.2e-66
Smith-Waterman score: 1079; 46.0% identity (77.1% similar) in 389 aa overlap (25-406:14-396)

               10        20          30        40        50        
pF1KB6 MQLFLLLCLVLLSPQGASLHRHHPREMK--KRVEDLHVGATVAPSSRRDFTFDLYRALAS
                               ::..  :.:  :   : ..  .:     .: : :. 
NP_001            MRSAGGRGEIKVRRELQPSKQVSGLTNHARTGQEKR-----NLQR-LVL
                          10        20        30             40    

       60        70        80        90       100       110        
pF1KB6 AAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQEL
        .:::.:::::::.: ::::::::: : :: :::.:::.:: .. :. .:.:::.:.. :
NP_001 ETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHSL
            50        60        70        80        90       100   

      120       130       140       150       160       170        
pF1KB6 NQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAK
       . :   . :..:.:::.   ..:: .:.. .: :: :..: :.: . . :. .::..: :
NP_001 TVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVKK
           110       120       130       140       150       160   

      180       190       200       210       220        230       
pF1KB6 QTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQ-DFYVTSETVVRVPMMS
       .:.::.::....::  .....::.::::::::  :. . :...  : :  ...:.:::: 
NP_001 KTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMH
           170       180       190       200       210       220   

       240       250       260       270       280       290       
pF1KB6 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR
       ...:. . .: .:.: :. . :.:.:.:.:.:::.:::.:.:..:: .::::: . ..::
NP_001 QKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKR
           230       240       250       260       270       280   

       300       310       320       330       340       350       
pF1KB6 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE
        .:...:.::: .::.:: .::..::.::: ..::.:::......:::. .::::..:.:
NP_001 WIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSE
           290       300       310       320       330       340   

       360       370       380        390          400         
pF1KB6 SGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVD---NNILFLGKVNRP   
        ::.:.::: : :  ::    :   : ::: :::.:..   ..:::::::. :   
NP_001 EGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS
           350       360       370       380       390         

>>NP_001121179 (OMIM: 107400,606963,613490) alpha-1-anti  (418 aa)
 initn: 1027 init1: 988 opt: 1053  Z-score: 1285.8  bits: 246.9 E(85289): 7e-65
Smith-Waterman score: 1053; 43.9% identity (73.0% similar) in 408 aa overlap (6-406:15-415)

                        10            20        30        40       
pF1KB6          MQLFLLLCLVLLS----PQGASLHRHHPREMKKRVEDLHVGATVAPSSRRD
                     : ::: .:    ::: . ..    . ... .:  .   ..:.   .
NP_001 MPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQK---TDTSHHDQDHPTFNKITPNLA-E
               10        20        30           40        50       

        50        60        70        80        90       100       
pF1KB6 FTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKEL
       :.:.::: ::  . : .::::::::. ..::::::. ..:. .:::::..:: .  : ..
NP_001 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI
         60        70        80        90       100       110      

       110       120       130       140       150       160       
pF1KB6 HRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAG
       :.:::.::. :::: . .::. ::.:: .  . : : :.  .: :: ...: .:: :.  
NP_001 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEE
        120       130       140       150       160       170      

       170       180       190       200       210       220       
pF1KB6 AMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTS
       : ::::::: : :.::::::.:.:: ..:  .:::::::.:::  :. : :.:.::.: .
NP_001 AKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQ
        180       190       200       210       220       230      

       230       240       250       260       270       280       
pF1KB6 ETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTL
        :.:.::::.:  ...    ..::  :. . : :::::.:.::.:::.:..:: :..  .
NP_001 VTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDII
        240       250       260       270       280       290      

       290       300       310       320       330       340       
pF1KB6 RKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEM
        :.:.   .:.  :.:::.:: :.:.:..:: .:::..::.. :::::..... ...:. 
NP_001 TKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKA
        300       310       320       330       340       350      

       350       360       370       380       390          400    
pF1KB6 VHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVN
       :::::. .::.::.::   :..:          .. ::.::.......:    ::.::: 
NP_001 VHKAVLTIDEKGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVV
        360       370          380       390       400       410   

            
pF1KB6 RP   
        :   
NP_001 NPTQK
            




406 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 01:19:58 2016 done: Sat Nov  5 01:19:59 2016
 Total Scan time:  8.570 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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