Result of FASTA (omim) for pF1KB7680
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7680, 406 aa
  1>>>pF1KB7680 406 - 406 aa - 406 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.0053+/-0.000386; mu= 5.2419+/- 0.024
 mean_var=430.2708+/-88.405, 0's: 0 Z-trim(124.4): 21  B-trim: 0 in 0/60
 Lambda= 0.061831
 statistics sampled from 46079 (46129) to 46079 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.812), E-opt: 0.2 (0.541), width:  16
 Scan time: 11.370

The best scores are:                                      opt bits E(85289)
NP_002922 (OMIM: 602045) E3 ubiquitin-protein liga ( 406) 2796 263.2 8.4e-70
XP_011508153 (OMIM: 608985) PREDICTED: E3 ubiquiti ( 336)  882 92.3 1.9e-18
XP_011508154 (OMIM: 608985) PREDICTED: E3 ubiquiti ( 336)  882 92.3 1.9e-18
NP_009143 (OMIM: 608985) E3 ubiquitin-protein liga ( 336)  882 92.3 1.9e-18
XP_005245470 (OMIM: 608985) PREDICTED: E3 ubiquiti ( 287)  674 73.7 6.7e-13


>>NP_002922 (OMIM: 602045) E3 ubiquitin-protein ligase R  (406 aa)
 initn: 2796 init1: 2796 opt: 2796  Z-score: 1374.1  bits: 263.2 E(85289): 8.4e-70
Smith-Waterman score: 2796; 100.0% identity (100.0% similar) in 406 aa overlap (1-406:1-406)

               10        20        30        40        50        60
pF1KB7 MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 TKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 QDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPGEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPGEGE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 GDGEDVSSDSAPDSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRGGTLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GDGEDVSSDSAPDSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRGGTLG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 GGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLSKYLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLSKYLA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 LRIALERRQQQEAGEPGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGVSEKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LRIALERRQQQEAGEPGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGVSEKQ
              310       320       330       340       350       360

              370       380       390       400      
pF1KB7 YTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK
              370       380       390       400      

>>XP_011508153 (OMIM: 608985) PREDICTED: E3 ubiquitin-pr  (336 aa)
 initn: 1379 init1: 872 opt: 882  Z-score: 452.2  bits: 92.3 E(85289): 1.9e-18
Smith-Waterman score: 1244; 55.2% identity (69.8% similar) in 400 aa overlap (8-406:11-336)

                  10        20        30        40        50       
pF1KB7    MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKN
                 :  :::::::::::.::::::: :: ::.:::::::::::::::::::::
XP_011 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB7 TMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEY
       ::::::::::::.:::.::::::::::::::::::::::::::::::::::::::::.::
XP_011 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB7 EAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPG
       ::::.::: :... .:::::: ::::::..:::.: ::      :. :   . .: :  .
XP_011 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQR------GKKQ--QIENGSG--A
              130       140       150             160           170

       180       190        200       210       220       230      
pF1KB7 EGEGDGEDVSSDSA-PDSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRG
       : .::.   :. :.  ..  ::. :: .                        :.::: . 
XP_011 EDNGDSSHCSNASTHSNQEAGPSNKRTKT-----------------------SDDSGLEL
              180       190                              200       

        240       250       260       270       280       290      
pF1KB7 GTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLS
        . ...    :   ::       .:::::::::: :.:: .  ::::.::.:::::::::
XP_011 DNNNAAMAIDPVMDGA-------SEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLS
       210       220              230       240       250       260

        300       310       320       330       340       350      
pF1KB7 KYLALRIALERRQQQEAGEPGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGV
       ::::.:.:::. ...                      ::..              .:. .
XP_011 KYLAVRLALEELRSK----------------------GESNQM------------NLDTA
              270                             280                  

        360       370       380       390       400      
pF1KB7 SEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK
       :::::::::: ..: ::.::::..::::.::.:::..:.:: :::::. :
XP_011 SEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
        290       300       310       320       330      

>>XP_011508154 (OMIM: 608985) PREDICTED: E3 ubiquitin-pr  (336 aa)
 initn: 1379 init1: 872 opt: 882  Z-score: 452.2  bits: 92.3 E(85289): 1.9e-18
Smith-Waterman score: 1244; 55.2% identity (69.8% similar) in 400 aa overlap (8-406:11-336)

                  10        20        30        40        50       
pF1KB7    MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKN
                 :  :::::::::::.::::::: :: ::.:::::::::::::::::::::
XP_011 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB7 TMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEY
       ::::::::::::.:::.::::::::::::::::::::::::::::::::::::::::.::
XP_011 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB7 EAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPG
       ::::.::: :... .:::::: ::::::..:::.: ::      :. :   . .: :  .
XP_011 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQR------GKKQ--QIENGSG--A
              130       140       150             160           170

       180       190        200       210       220       230      
pF1KB7 EGEGDGEDVSSDSA-PDSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRG
       : .::.   :. :.  ..  ::. :: .                        :.::: . 
XP_011 EDNGDSSHCSNASTHSNQEAGPSNKRTKT-----------------------SDDSGLEL
              180       190                              200       

        240       250       260       270       280       290      
pF1KB7 GTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLS
        . ...    :   ::       .:::::::::: :.:: .  ::::.::.:::::::::
XP_011 DNNNAAMAIDPVMDGA-------SEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLS
       210       220              230       240       250       260

        300       310       320       330       340       350      
pF1KB7 KYLALRIALERRQQQEAGEPGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGV
       ::::.:.:::. ...                      ::..              .:. .
XP_011 KYLAVRLALEELRSK----------------------GESNQM------------NLDTA
              270                             280                  

        360       370       380       390       400      
pF1KB7 SEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK
       :::::::::: ..: ::.::::..::::.::.:::..:.:: :::::. :
XP_011 SEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
        290       300       310       320       330      

>>NP_009143 (OMIM: 608985) E3 ubiquitin-protein ligase R  (336 aa)
 initn: 1379 init1: 872 opt: 882  Z-score: 452.2  bits: 92.3 E(85289): 1.9e-18
Smith-Waterman score: 1244; 55.2% identity (69.8% similar) in 400 aa overlap (8-406:11-336)

                  10        20        30        40        50       
pF1KB7    MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKN
                 :  :::::::::::.::::::: :: ::.:::::::::::::::::::::
NP_009 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB7 TMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEY
       ::::::::::::.:::.::::::::::::::::::::::::::::::::::::::::.::
NP_009 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB7 EAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPG
       ::::.::: :... .:::::: ::::::..:::.: ::      :. :   . .: :  .
NP_009 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQR------GKKQ--QIENGSG--A
              130       140       150             160           170

       180       190        200       210       220       230      
pF1KB7 EGEGDGEDVSSDSA-PDSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRG
       : .::.   :. :.  ..  ::. :: .                        :.::: . 
NP_009 EDNGDSSHCSNASTHSNQEAGPSNKRTKT-----------------------SDDSGLEL
              180       190                              200       

        240       250       260       270       280       290      
pF1KB7 GTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLS
        . ...    :   ::       .:::::::::: :.:: .  ::::.::.:::::::::
NP_009 DNNNAAMAIDPVMDGA-------SEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLS
       210       220              230       240       250       260

        300       310       320       330       340       350      
pF1KB7 KYLALRIALERRQQQEAGEPGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGV
       ::::.:.:::. ...                      ::..              .:. .
NP_009 KYLAVRLALEELRSK----------------------GESNQM------------NLDTA
              270                             280                  

        360       370       380       390       400      
pF1KB7 SEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK
       :::::::::: ..: ::.::::..::::.::.:::..:.:: :::::. :
NP_009 SEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
        290       300       310       320       330      

>>XP_005245470 (OMIM: 608985) PREDICTED: E3 ubiquitin-pr  (287 aa)
 initn: 1174 init1: 667 opt: 674  Z-score: 352.6  bits: 73.7 E(85289): 6.7e-13
Smith-Waterman score: 1036; 52.1% identity (67.6% similar) in 361 aa overlap (47-406:1-287)

         20        30        40        50        60        70      
pF1KB7 SLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTA
                                     :::::::::::::::::::::::.:::.::
XP_005                               MCPICLDMLKNTMTTKECLHRFCADCIITA
                                             10        20        30

         80        90       100       110       120       130      
pF1KB7 LRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQA
       ::::::::::::::::::::::::::::::::::::::.::::::.::: :... .::::
XP_005 LRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQA
               40        50        60        70        80        90

        140       150       160       170       180       190      
pF1KB7 LSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPGEGEGDGEDVSSDSA-PDSA
       :: ::::::..:::.: ::      :. :   . .: :  .: .::.   :. :.  .. 
XP_005 LSHSIEEGLKIQAMNRLQR------GKKQQ--IENGSG--AEDNGDSSHCSNASTHSNQE
              100             110         120         130       140

         200       210       220       230       240       250     
pF1KB7 PGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRGGTLGGGTLGPPSPPGAPSP
        ::. :: .                        :.::: .  . ...    :   ::   
XP_005 AGPSNKRTKT-----------------------SDDSGLELDNNNAAMAIDPVMDGA---
              150                              160       170       

         260       270       280       290       300       310     
pF1KB7 PEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLSKYLALRIALERRQQQEAGE
           .:::::::::: :.:: .  ::::.::.:::::::::::::.:.:::. ...    
XP_005 ----SEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSK----
              180       190       200       210       220          

         320       330       340       350       360       370     
pF1KB7 PGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTL
                         ::..              .:. .:::::::::: ..: ::.:
XP_005 ------------------GESNQM------------NLDTASEKQYTIYIATASGQFTVL
                          230                   240       250      

         380       390       400      
pF1KB7 NGSLTLELVNEKFWKVSRPLELCYAPTKDPK
       :::..::::.::.:::..:.:: :::::. :
XP_005 NGSFSLELVSEKYWKVNKPMELYYAPTKEHK
        260       270       280       




406 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 21:32:01 2016 done: Fri Nov  4 21:32:03 2016
 Total Scan time: 11.370 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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