Result of FASTA (omim) for pF1KB6768
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6768, 148 aa
  1>>>pF1KB6768 148 - 148 aa - 148 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3307+/-0.000338; mu= 11.9319+/- 0.021
 mean_var=75.1877+/-15.184, 0's: 0 Z-trim(116.4): 32  B-trim: 901 in 1/54
 Lambda= 0.147911
 statistics sampled from 27552 (27586) to 27552 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.323), width:  16
 Scan time:  4.970

The best scores are:                                      opt bits E(85289)
NP_000919 (OMIM: 172410) phospholipase A2 precurso ( 148) 1057 234.2 5.9e-62
NP_001155201 (OMIM: 172411) phospholipase A2, memb ( 144)  338 80.8 8.8e-16
NP_000291 (OMIM: 172411) phospholipase A2, membran ( 144)  338 80.8 8.8e-16
NP_001155199 (OMIM: 172411) phospholipase A2, memb ( 144)  338 80.8 8.8e-16
NP_001155200 (OMIM: 172411) phospholipase A2, memb ( 144)  338 80.8 8.8e-16
NP_036532 (OMIM: 605630) group IID secretory phosp ( 145)  325 78.0 6.1e-15
NP_003552 (OMIM: 603603) group 10 secretory phosph ( 165)  314 75.7 3.4e-14
XP_011540258 (OMIM: 616793) PREDICTED: group IIF s ( 211)  304 73.6 1.8e-13
NP_073730 (OMIM: 616793) group IIF secretory phosp ( 211)  304 73.6 1.8e-13
NP_001073868 (OMIM: 601658) otoconin-90 precursor  ( 477)  269 66.4 6.1e-11
XP_011539890 (OMIM: 228980,601192) PREDICTED: calc ( 138)  262 64.5 6.5e-11
XP_011539893 (OMIM: 228980,601192) PREDICTED: calc ( 138)  262 64.5 6.5e-11
XP_005245950 (OMIM: 228980,601192) PREDICTED: calc ( 138)  262 64.5 6.5e-11
NP_000920 (OMIM: 228980,601192) calcium-dependent  ( 138)  262 64.5 6.5e-11
XP_011539889 (OMIM: 228980,601192) PREDICTED: calc ( 138)  262 64.5 6.5e-11
XP_011539894 (OMIM: 228980,601192) PREDICTED: calc ( 138)  262 64.5 6.5e-11
XP_011539891 (OMIM: 228980,601192) PREDICTED: calc ( 138)  262 64.5 6.5e-11
XP_011539892 (OMIM: 228980,601192) PREDICTED: calc ( 138)  262 64.5 6.5e-11
XP_005245949 (OMIM: 228980,601192) PREDICTED: calc ( 169)  262 64.6 7.6e-11
XP_011539888 (OMIM: 228980,601192) PREDICTED: calc ( 169)  262 64.6 7.6e-11
XP_005245948 (OMIM: 228980,601192) PREDICTED: calc ( 169)  262 64.6 7.6e-11
XP_011520997 (OMIM: 603603) PREDICTED: group 10 se ( 133)  238 59.4 2.2e-09
XP_011521000 (OMIM: 603603) PREDICTED: group 10 se ( 120)  231 57.9 5.7e-09
XP_011520999 (OMIM: 603603) PREDICTED: group 10 se ( 124)  231 57.9 5.9e-09
XP_011520998 (OMIM: 603603) PREDICTED: group 10 se ( 131)  231 57.9 6.1e-09
XP_011540257 (OMIM: 616793) PREDICTED: group IIF s ( 219)  214 54.4 1.1e-07
NP_001258743 (OMIM: 605630) group IID secretory ph (  62)  143 38.9  0.0015


>>NP_000919 (OMIM: 172410) phospholipase A2 precursor [H  (148 aa)
 initn: 1057 init1: 1057 opt: 1057  Z-score: 1233.3  bits: 234.2 E(85289): 5.9e-62
Smith-Waterman score: 1057; 100.0% identity (100.0% similar) in 148 aa overlap (1-148:1-148)

               10        20        30        40        50        60
pF1KB6 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
               70        80        90       100       110       120

              130       140        
pF1KB6 DRNAAICFSKAPYNKAHKNLDTKKYCQS
       ::::::::::::::::::::::::::::
NP_000 DRNAAICFSKAPYNKAHKNLDTKKYCQS
              130       140        

>>NP_001155201 (OMIM: 172411) phospholipase A2, membrane  (144 aa)
 initn: 316 init1: 197 opt: 338  Z-score: 404.3  bits: 80.8 E(85289): 8.8e-16
Smith-Waterman score: 338; 39.5% identity (65.8% similar) in 152 aa overlap (1-147:1-138)

                10        20        30        40        50         
pF1KB6 MK-LLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP
       :: ::.:::..  .  ..  .   . .:..::: .  :..  : :. :::.::.:: :.:
NP_001 MKTLLLLAVIMIFGLLQAHGN---LVNFHRMIK-LTTGKEAALSYGFYGCHCGVGGRGSP
               10        20           30         40        50      

      60        70        80          90       100       110       
pF1KB6 VDELDKCCQTHDNCYDQAKKLDSC--KFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFI
        :  :.:: ::: :: . .:  .:  :::       .:..: ::: :::. :.  :.. .
NP_001 KDATDRCCVTHDCCYKRLEK-RGCGTKFL-------SYKFSNSGSRITCA-KQDSCRSQL
         60        70         80               90        100       

       120         130       140             
pF1KB6 CNCDRNAAICFS--KAPYNKAHKNLDTKKYCQS     
       :.::. :: ::.  :. ::: ..   ..:.:.      
NP_001 CECDKAAATCFARNKTTYNKKYQYY-SNKHCRGSTPRC
       110       120       130        140    

>>NP_000291 (OMIM: 172411) phospholipase A2, membrane as  (144 aa)
 initn: 316 init1: 197 opt: 338  Z-score: 404.3  bits: 80.8 E(85289): 8.8e-16
Smith-Waterman score: 338; 39.5% identity (65.8% similar) in 152 aa overlap (1-147:1-138)

                10        20        30        40        50         
pF1KB6 MK-LLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP
       :: ::.:::..  .  ..  .   . .:..::: .  :..  : :. :::.::.:: :.:
NP_000 MKTLLLLAVIMIFGLLQAHGN---LVNFHRMIK-LTTGKEAALSYGFYGCHCGVGGRGSP
               10        20           30         40        50      

      60        70        80          90       100       110       
pF1KB6 VDELDKCCQTHDNCYDQAKKLDSC--KFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFI
        :  :.:: ::: :: . .:  .:  :::       .:..: ::: :::. :.  :.. .
NP_000 KDATDRCCVTHDCCYKRLEK-RGCGTKFL-------SYKFSNSGSRITCA-KQDSCRSQL
         60        70         80               90        100       

       120         130       140             
pF1KB6 CNCDRNAAICFS--KAPYNKAHKNLDTKKYCQS     
       :.::. :: ::.  :. ::: ..   ..:.:.      
NP_000 CECDKAAATCFARNKTTYNKKYQYY-SNKHCRGSTPRC
       110       120       130        140    

>>NP_001155199 (OMIM: 172411) phospholipase A2, membrane  (144 aa)
 initn: 316 init1: 197 opt: 338  Z-score: 404.3  bits: 80.8 E(85289): 8.8e-16
Smith-Waterman score: 338; 39.5% identity (65.8% similar) in 152 aa overlap (1-147:1-138)

                10        20        30        40        50         
pF1KB6 MK-LLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP
       :: ::.:::..  .  ..  .   . .:..::: .  :..  : :. :::.::.:: :.:
NP_001 MKTLLLLAVIMIFGLLQAHGN---LVNFHRMIK-LTTGKEAALSYGFYGCHCGVGGRGSP
               10        20           30         40        50      

      60        70        80          90       100       110       
pF1KB6 VDELDKCCQTHDNCYDQAKKLDSC--KFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFI
        :  :.:: ::: :: . .:  .:  :::       .:..: ::: :::. :.  :.. .
NP_001 KDATDRCCVTHDCCYKRLEK-RGCGTKFL-------SYKFSNSGSRITCA-KQDSCRSQL
         60        70         80               90        100       

       120         130       140             
pF1KB6 CNCDRNAAICFS--KAPYNKAHKNLDTKKYCQS     
       :.::. :: ::.  :. ::: ..   ..:.:.      
NP_001 CECDKAAATCFARNKTTYNKKYQYY-SNKHCRGSTPRC
       110       120       130        140    

>>NP_001155200 (OMIM: 172411) phospholipase A2, membrane  (144 aa)
 initn: 316 init1: 197 opt: 338  Z-score: 404.3  bits: 80.8 E(85289): 8.8e-16
Smith-Waterman score: 338; 39.5% identity (65.8% similar) in 152 aa overlap (1-147:1-138)

                10        20        30        40        50         
pF1KB6 MK-LLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP
       :: ::.:::..  .  ..  .   . .:..::: .  :..  : :. :::.::.:: :.:
NP_001 MKTLLLLAVIMIFGLLQAHGN---LVNFHRMIK-LTTGKEAALSYGFYGCHCGVGGRGSP
               10        20           30         40        50      

      60        70        80          90       100       110       
pF1KB6 VDELDKCCQTHDNCYDQAKKLDSC--KFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFI
        :  :.:: ::: :: . .:  .:  :::       .:..: ::: :::. :.  :.. .
NP_001 KDATDRCCVTHDCCYKRLEK-RGCGTKFL-------SYKFSNSGSRITCA-KQDSCRSQL
         60        70         80               90        100       

       120         130       140             
pF1KB6 CNCDRNAAICFS--KAPYNKAHKNLDTKKYCQS     
       :.::. :: ::.  :. ::: ..   ..:.:.      
NP_001 CECDKAAATCFARNKTTYNKKYQYY-SNKHCRGSTPRC
       110       120       130        140    

>>NP_036532 (OMIM: 605630) group IID secretory phospholi  (145 aa)
 initn: 312 init1: 185 opt: 325  Z-score: 389.3  bits: 78.0 E(85289): 6.1e-15
Smith-Waterman score: 325; 40.2% identity (64.4% similar) in 132 aa overlap (1-130:1-121)

               10        20          30        40        50        
pF1KB6 MKLLVLAVLLTVAAADSGISP--RAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGT
       :.: .:  :...:    :. :   .. .. ::.: :  :. :.: :  :::.::::: : 
NP_036 MELALLCGLVVMA----GVIPIQGGILNLNKMVKQVT-GKMPILSYWPYGCHCGLGGRGQ
               10            20        30         40        50     

       60        70        80        90       100       110        
pF1KB6 PVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFIC
       : :  : :::::: :::. :  ..:..     :   : :. : . : ::.:.. ::  .:
NP_036 PKDATDWCCQTHDCCYDHLKT-QGCSI-----YKDYYRYNFSQGNIHCSDKGSWCEQQLC
          60        70         80             90       100         

      120       130       140              
pF1KB6 NCDRNAAICFSKAPYNKAHKNLDTKKYCQS      
        ::...:.:...                        
NP_036 ACDKEVAFCLKRNLDTYQKRLRFYWRPHCRGQTPGC
     110       120       130       140     

>>NP_003552 (OMIM: 603603) group 10 secretory phospholip  (165 aa)
 initn: 312 init1: 171 opt: 314  Z-score: 375.8  bits: 75.7 E(85289): 3.4e-14
Smith-Waterman score: 314; 35.4% identity (68.1% similar) in 113 aa overlap (22-134:42-146)

                        10        20        30        40        50 
pF1KB6          MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYC
                                     :.. ..   . :: : . : . : .:::.:
NP_003 LLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRT-P-IAYMKYGCFC
              20        30        40        50          60         

              60        70        80        90       100       110 
pF1KB6 GLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNK
       :::: : : : .: ::. :: :: .:..  .:     .: :. ::..: .... :.  ..
NP_003 GLGGHGQPRDAIDWCCHGHDCCYTRAEEA-GC-----SPKTERYSWQCVNQSVLCGPAEN
      70        80        90        100            110       120   

             120       130       140             
pF1KB6 ECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS     
       .:. ..:.::.. : :.... ::                   
NP_003 KCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
           130       140       150       160     

>>XP_011540258 (OMIM: 616793) PREDICTED: group IIF secre  (211 aa)
 initn: 290 init1: 178 opt: 304  Z-score: 362.7  bits: 73.6 E(85289): 1.8e-13
Smith-Waterman score: 304; 34.5% identity (64.2% similar) in 148 aa overlap (2-147:46-182)

                                            10         20        30
pF1KB6                              MKLLVLAVLL-TVAAADSGISPRAVWQFRKM
                                     :....:.:  .: ..  :    .. ... :
XP_011 VLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHG----SLLNLKAM
          20        30        40        50        60            70 

               40        50        60        70        80        90
pF1KB6 IKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNP
       .. :  : . .: . .::::::::: : : ::.: ::..:: :: :    ..:.  .:. 
XP_011 VEAVT-GRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCY-QELFDQGCHPYVDH-
               80        90       100       110        120         

              100       110        120       130       140         
pF1KB6 YTHTYSYSCSGSAITCSSKNK-ECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS 
       : ::     ... :.::. :: ::.   : ::.: ..:. .  : . ....  . :::  
XP_011 YDHTIE---NNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQTYREEYRGF-LNVYCQGP
      130          140       150       160       170        180    

XP_011 TPNCSIYEPPPEEVTCSHQSPAPPAPP
          190       200       210 

>>NP_073730 (OMIM: 616793) group IIF secretory phospholi  (211 aa)
 initn: 290 init1: 178 opt: 304  Z-score: 362.7  bits: 73.6 E(85289): 1.8e-13
Smith-Waterman score: 304; 34.5% identity (64.2% similar) in 148 aa overlap (2-147:46-182)

                                            10         20        30
pF1KB6                              MKLLVLAVLL-TVAAADSGISPRAVWQFRKM
                                     :....:.:  .: ..  :    .. ... :
NP_073 VLDRCFSGWRGPRFGASCPSRTSRSSLGMKKFFTVAILAGSVLSTAHG----SLLNLKAM
          20        30        40        50        60            70 

               40        50        60        70        80        90
pF1KB6 IKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNP
       .. :  : . .: . .::::::::: : : ::.: ::..:: :: :    ..:.  .:. 
NP_073 VEAVT-GRSAILSFVGYGCYCGLGGRGQPKDEVDWCCHAHDCCY-QELFDQGCHPYVDH-
               80        90       100       110        120         

              100       110        120       130       140         
pF1KB6 YTHTYSYSCSGSAITCSSKNK-ECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS 
       : ::     ... :.::. :: ::.   : ::.: ..:. .  : . ....  . :::  
NP_073 YDHTIE---NNTEIVCSDLNKTECDKQTCMCDKNMVLCLMNQTYREEYRGF-LNVYCQGP
      130          140       150       160       170        180    

NP_073 TPNCSIYEPPPEEVTCSHQSPAPPAPP
          190       200       210 

>>NP_001073868 (OMIM: 601658) otoconin-90 precursor [Hom  (477 aa)
 initn: 397 init1: 165 opt: 269  Z-score: 317.4  bits: 66.4 E(85289): 6.1e-11
Smith-Waterman score: 286; 36.4% identity (63.6% similar) in 121 aa overlap (26-146:78-190)

                    10        20        30        40        50     
pF1KB6      MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGG
                                     :: . .:::  :  :  ....::: : .  
NP_001 NVESVAEIFDCLGPHFTWLQAVFTNFPVLIQFVNGMKCVA-GLCPR-DFEDYGCTCRFEM
        50        60        70        80         90        100     

          60        70        80        90       100       110     
pF1KB6 SGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEA
        : :::: :.::  :  ::..: ..: :   :..:   .   .: .. : : ::.. :: 
NP_001 EGLPVDESDSCCFQHRRCYEEAAEMD-C---LQDPAKLSTEVNCVSKKIICESKDN-CEH
         110       120       130           140       150        160

         120       130       140                                   
pF1KB6 FICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS                           
       ..:.::. :  :....  :.. . :::. .:                             
NP_001 LLCTCDKAAIECLARSSLNSSLNLLDTS-FCLAQTPETTIKEDLTTLLPRVVPVEPTDTS
              170       180        190       200       210         

NP_001 LTALSGEEAGHDQEGVGAARATSPPGSAEIVATRVTAKIVTLVPAGIKSLGLAVSSVEND
     220       230       240       250       260       270         

>--
 initn: 397 init1: 165 opt: 269  Z-score: 317.4  bits: 66.4 E(85289): 6.1e-11
Smith-Waterman score: 269; 33.3% identity (65.9% similar) in 123 aa overlap (17-139:298-412)

                             10        20        30        40      
pF1KB6               MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNN
                                     :: . ... :. .:. : . .  :  :...
NP_001 SLGLAVSSVENDPEETTEKACDRFTFLHLGSGDNMQVMPQLGEMLFC-LTSRCPE-EFES
       270       280       290       300       310        320      

         50        60        70        80        90       100      
pF1KB6 YGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITC
       ::::::  : : : :.::.:: .:  : .:...: .: .:   :.. .    :   .  :
NP_001 YGCYCGQEGRGEPRDDLDRCCLSHHCCLEQVRRL-GC-LLERLPWSPVV---CVDHTPKC
         330       340       350        360        370          380

        110       120       130       140                          
pF1KB6 SSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS                  
       ....  :: ..: ::..:: :...: .:.. :.                           
NP_001 GGQSL-CEKLLCACDQTAAECMTSASFNQSLKSPSRLGCPGQPAACEDSLHPVPAAPTLG
               390       400       410       420       430         

NP_001 SSSEEDSEEDPPQEDLGRAKRFLRKSLGPLGIGPLHGR
     440       450       460       470       




148 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 23:54:04 2016 done: Fri Nov  4 23:54:05 2016
 Total Scan time:  4.970 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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