Result of FASTA (omim) for
pF1KB8950
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8950, 324 aa
1>>>pF1KB8950 324 - 324 aa - 324 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6474+/-0.000319; mu= 9.3387+/- 0.020
mean_var=231.0137+/-48.161, 0's: 0 Z-trim(123.9): 247 B-trim: 2243 in 1/58
Lambda= 0.084383
statistics sampled from 44425 (44695) to 44425 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.807), E-opt: 0.2 (0.524), width: 16
Scan time: 6.970
The best scores are: opt bits E(85289)
NP_004378 (OMIM: 108900,187500,217095,225250,60058 ( 324) 2213 281.3 1.8e-75
NP_001159648 (OMIM: 108900,187500,217095,225250,60 ( 151) 746 102.4 6.4e-22
NP_001159647 (OMIM: 108900,187500,217095,225250,60 ( 112) 742 101.7 7.4e-22
XP_016864560 (OMIM: 108900,187500,217095,225250,60 ( 142) 742 101.8 8.7e-22
NP_001129743 (OMIM: 217095,611770) homeobox protei ( 301) 718 99.3 1.1e-20
NP_660328 (OMIM: 606727) homeobox protein Nkx-2.3 ( 364) 713 98.8 1.8e-20
NP_149416 (OMIM: 607808) homeobox protein Nkx-2.4 ( 354) 480 70.4 6.3e-12
NP_002500 (OMIM: 604612) homeobox protein Nkx-2.2 ( 273) 466 68.6 1.7e-11
XP_006723629 (OMIM: 604612) PREDICTED: homeobox pr ( 202) 450 66.5 5.5e-11
NP_055175 (OMIM: 603245) homeobox protein Nkx-2.8 ( 239) 433 64.5 2.6e-10
NP_001180 (OMIM: 602183,613330) homeobox protein N ( 333) 364 56.3 1.1e-07
NP_061815 (OMIM: 142992,612109) homeobox protein H ( 348) 341 53.5 7.7e-07
NP_003308 (OMIM: 118700,188550,600635,610978) home ( 371) 334 52.7 1.4e-06
NP_001073136 (OMIM: 118700,188550,600635,610978) h ( 401) 334 52.7 1.5e-06
NP_002439 (OMIM: 106600,142983,189500,608874) home ( 303) 303 48.8 1.7e-05
NP_001243268 (OMIM: 602041) homeobox protein Nkx-3 ( 159) 278 45.4 9.4e-05
NP_006158 (OMIM: 602041) homeobox protein Nkx-3.1 ( 234) 278 45.6 0.00012
NP_001009812 (OMIM: 607164) transcription factor L ( 194) 272 44.8 0.00018
NP_005510 (OMIM: 600647) homeobox protein HMX2 [Ho ( 273) 272 45.0 0.00022
XP_005269800 (OMIM: 600647) PREDICTED: homeobox pr ( 273) 272 45.0 0.00022
NP_612138 (OMIM: 601911,616788) homeobox protein D ( 240) 271 44.8 0.00022
NP_002440 (OMIM: 123101,168500,168550,604757) home ( 267) 270 44.7 0.00026
NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 271 45.0 0.00029
NP_006553 (OMIM: 604255) transcription factor LBX1 ( 281) 268 44.5 0.00032
NP_001269359 (OMIM: 607164) transcription factor L ( 198) 265 43.9 0.00033
NP_001099044 (OMIM: 613380) homeobox protein HMX3 ( 357) 269 44.7 0.00034
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 268 44.6 0.00036
NP_001091639 (OMIM: 611074) brain-specific homeobo ( 233) 258 43.2 0.00065
XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 259 43.6 0.00089
XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 259 43.6 0.00089
XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 259 43.6 0.00089
XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 259 43.6 0.00089
XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 259 43.6 0.00089
XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 259 43.6 0.00089
NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 259 43.6 0.00089
XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 259 43.6 0.00089
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 259 43.6 0.00091
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 259 43.6 0.00091
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 259 43.6 0.00091
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 259 43.6 0.00091
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 259 43.6 0.00091
XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 259 43.6 0.00091
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 259 43.6 0.00091
NP_005211 (OMIM: 104510,190320,600525) homeobox pr ( 287) 254 42.8 0.001
XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 251 42.5 0.0014
NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 249 42.2 0.0017
NP_005212 (OMIM: 220600,600028) homeobox protein D ( 289) 247 41.9 0.0019
NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 246 41.8 0.0021
NP_064447 (OMIM: 605212) barH-like 2 homeobox prot ( 387) 247 42.1 0.0023
NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 246 41.9 0.0024
>>NP_004378 (OMIM: 108900,187500,217095,225250,600584,61 (324 aa)
initn: 2213 init1: 2213 opt: 2213 Z-score: 1475.8 bits: 281.3 E(85289): 1.8e-75
Smith-Waterman score: 2213; 100.0% identity (100.0% similar) in 324 aa overlap (1-324:1-324)
10 20 30 40 50 60
pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 QVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 YGVGLNPYGYNAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YGVGLNPYGYNAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDL
250 260 270 280 290 300
310 320
pF1KB8 NAVQSPGIPQSNSGVSTLHGIRAW
::::::::::::::::::::::::
NP_004 NAVQSPGIPQSNSGVSTLHGIRAW
310 320
>>NP_001159648 (OMIM: 108900,187500,217095,225250,600584 (151 aa)
initn: 742 init1: 742 opt: 746 Z-score: 514.5 bits: 102.4 E(85289): 6.4e-22
Smith-Waterman score: 746; 95.8% identity (96.6% similar) in 118 aa overlap (1-118:1-117)
10 20 30 40 50 60
pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAV
::::::::::::::::::::::::::::::::::::::::::::::::::: : : .
NP_001 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKG-CELPRGQ
70 80 90 100 110
130 140 150 160 170 180
pF1KB8 ELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTST
NP_001 RPPVLFSSALSQPDFLQMLSETCRWLPVHLAE
120 130 140 150
>>NP_001159647 (OMIM: 108900,187500,217095,225250,600584 (112 aa)
initn: 742 init1: 742 opt: 742 Z-score: 513.3 bits: 101.7 E(85289): 7.4e-22
Smith-Waterman score: 742; 100.0% identity (100.0% similar) in 111 aa overlap (1-111:1-111)
10 20 30 40 50 60
pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAV
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKA
70 80 90 100 110
130 140 150 160 170 180
pF1KB8 ELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTST
>>XP_016864560 (OMIM: 108900,187500,217095,225250,600584 (142 aa)
initn: 742 init1: 742 opt: 742 Z-score: 512.1 bits: 101.8 E(85289): 8.7e-22
Smith-Waterman score: 744; 85.0% identity (87.1% similar) in 140 aa overlap (1-139:1-130)
10 20 30 40 50 60
pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAV
::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKAQLA-----
70 80 90 100 110
130 140 150 160 170
pF1KB8 ELEKTEADNAER-PRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTS
: ::: ::.. :.
XP_016 -----GAARAERFPRGKVRKCCATAGTREWTR
120 130 140
>>NP_001129743 (OMIM: 217095,611770) homeobox protein Nk (301 aa)
initn: 652 init1: 424 opt: 718 Z-score: 492.6 bits: 99.3 E(85289): 1.1e-20
Smith-Waterman score: 759; 45.2% identity (65.2% similar) in 330 aa overlap (1-324:1-301)
10 20 30 40 50 60
pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE
:. :: .: ::::::::: ::.. :: :: : . .. .: . . . : ..
NP_001 MLLSP-VTSTPFSVKDILRLERE-RSCPAA---SPHPRVRKSPENFQYLRMDAEPRGSEV
10 20 30 40 50
70 80 90 100 110
pF1KB8 AAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDP---AKDPRAEKKELCALQ
: : : : : . : ... . . ...:.: : .: . ..
NP_001 HNAGGGGGDRKLDGSEPPGGPCEAVLE----MDAERMGEPQPGLNAASPLGGGTRVPERG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 KAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKL
. ..... .:.:.::.::::::::::::: ::::::::::::::::..:::.:.:
NP_001 VGNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 TSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPY
::::::::::::::::::::::..:::.: : : ::.:::::::::::::: . :
NP_001 TSTQVKIWFQNRRYKCKRQRQDKSLELAGHPLTP----RRVAVPVLVRDGKPCLGPG-PG
180 190 200 210 220
240 250 260 270 280 290
pF1KB8 APAYGVGLNPYG--YNAYPAYPGYGGAACSPGY-SCTAAYPAGPSPAQPATAAANNNFVN
:::. .::. . : : ::.:: . :: .: :. :.::.: : ..: .
NP_001 APAFP---SPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASA------G
230 240 250 260 270
300 310 320
pF1KB8 FGVGDLNAVQSPGIPQSNSGVSTLHGIRAW
:: : ::. ::.. . .::.:.:::
NP_001 FGHGGQNAT-----PQGHLA-ATLQGVRAW
280 290 300
>>NP_660328 (OMIM: 606727) homeobox protein Nkx-2.3 [Hom (364 aa)
initn: 680 init1: 491 opt: 713 Z-score: 488.3 bits: 98.8 E(85289): 1.8e-20
Smith-Waterman score: 861; 47.3% identity (65.2% similar) in 376 aa overlap (1-324:2-364)
10 20 30 40 50
pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYA-G
:.::: .: ::::::::::::::.. . .: .:.: :: . . ::::: . .. :
NP_660 MMLPSP-VTSTPFSVKDILNLEQQHQHFHGA-HLQADLEHHFHSAPCMLAAAEGTQFSDG
10 20 30 40 50
60 70 80 90 100
pF1KB8 PEAAAPG-------LPELRAELGRAPSPAKCASAFPAA----PAFYPRAYSD-PDPAKDP
: : : : :.. : . : ... . :. . . :. ..:
NP_660 GEEDEEDEGEKLSYLNSLAAADGHGDS-GLCPQGYVHTVLRDSCSEPKEHEEEPEVVRD-
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 RAEKKELCALQKAVEL--EKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLS
:..:. : :.:..: . :...:::. : :::::::::::::.:::::::::::::
NP_660 RSQKS--CQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 APERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLV
::::..::: :::::::::::::::::::::::::..::: : ::::: ::.::::::
NP_660 APEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLEL-GAHAPPPPP-RRVAVPVLV
180 190 200 210 220 230
230 240 250 260
pF1KB8 RDGKPCLGDSAP-YAPAYGVGLNPYGYNAYPAYPGYGG---------------AACSPGY
::::::. :: :. :.:: . :.::..::: :::. :: : .:
NP_660 RDGKPCVTPSAQAYGAPYSVGASAYSYNSFPAY-GYGNSAAAAAAAAAAAAAAAAYSSSY
240 250 260 270 280 290
270 280 290 300 310
pF1KB8 SCTAAYPAG-----------PSPAQPATAAANNN-FVNFGVGDLNAVQSPGIPQ-----S
.: ::::: . ::: .::... ::: :..:.. : : : .
NP_660 GC--AYPAGGGGGGGGTSAATTAMQPACSAAGGGPFVN--VSNLGGFGSGGSAQPLHQGT
300 310 320 330 340
320
pF1KB8 NSGVS----TLHGIRAW
.:.. ::.:::::
NP_660 AAGAACAQGTLQGIRAW
350 360
>>NP_149416 (OMIM: 607808) homeobox protein Nkx-2.4 [Hom (354 aa)
initn: 484 init1: 335 opt: 480 Z-score: 335.2 bits: 70.4 E(85289): 6.3e-12
Smith-Waterman score: 484; 42.7% identity (62.9% similar) in 248 aa overlap (9-236:51-294)
10 20 30
pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLE
: : .. .. .: : : ::. .:
NP_149 EETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPSHAMAGHNAAAAA
30 40 50 60 70 80
40 50 60 70 80
pF1KB8 ATLAPSSCMLAAFK--PEAYAGPEAAAP-----GLPELRAELGRAPSPAKCASA---FPA
:. : .. :... : . :..: :: .. .:: . . ..: . :
NP_149 AAAAAAAAAAATYHMPPGVSQFPHGAMGSYCNGGLGNM-GELPAYTDGMRGGAATGWYGA
90 100 110 120 130
90 100 110 120 130 140
pF1KB8 APAFYPRAYSDPDPAKDPRA--EKKELCALQKAVELEKTEAD-NAERPRARRRRKPRVLF
: :: ::. . : : . . .: .. :. . .: : ::: ::::
NP_149 NPD--PR-YSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLHAAAAAAAPRRKRRVLF
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB8 SQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELV
:::::::::::::::.:::::::..:::...:: :::::::::.::: ::: .:.. . .
NP_149 SQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQL
200 210 220 230 240 250
210 220 230 240 250
pF1KB8 ----GL-PPPPPPPA-RRIAVPVLVRDGKPCL-GDSAPYAPAYGVGLNPYGYNAYPAYPG
:: :::::::. ::.::::::.::::: : :.:
NP_149 QQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGASTPTPGQAGPQPPAPTPAPELEELS
260 270 280 290 300 310
260 270 280 290 300 310
pF1KB8 YGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGIPQSNSGVSTL
NP_149 PSPPALHGPGGGLAALDAAAGEYSGGVLGANLLYGRTW
320 330 340 350
>>NP_002500 (OMIM: 604612) homeobox protein Nkx-2.2 [Hom (273 aa)
initn: 383 init1: 348 opt: 466 Z-score: 327.3 bits: 68.6 E(85289): 1.7e-11
Smith-Waterman score: 466; 36.9% identity (60.2% similar) in 279 aa overlap (8-275:6-264)
10 20 30 40 50 60
pF1KB8 MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPE
: : :::::::.: . . ....: : . .: .: :::
NP_002 MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPE--EENEGP--------EPAKRAGPL
10 20 30 40
70 80 90 100 110
pF1KB8 A-----AAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCA
. :. .:: . .: : . . .. . : .: ... : :
NP_002 GQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB8 LQKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVL
.. . ..: . ... : ..:: :::::.::.:::::::.::::::::::..:::..
NP_002 DESPDNDKETPGGGGD---AGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB8 KLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSA
.:: :::::::::.::: :: : .. .:.. :: : ::.:::::::::::: . .:
NP_002 RLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLPSP-----RRVAVPVLVRDGKPCHALKA
170 180 190 200 210 220
240 250 260 270 280
pF1KB8 P--YAPAYGVGLNPYGYNA----YPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAAN
: .. .:. .:.: . : . ..: .: : .:.:
NP_002 QDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSSASTPQY--PTAHPLVQAQQWTW
230 240 250 260 270
290 300 310 320
pF1KB8 NNFVNFGVGDLNAVQSPGIPQSNSGVSTLHGIRAW
>>XP_006723629 (OMIM: 604612) PREDICTED: homeobox protei (202 aa)
initn: 348 init1: 348 opt: 450 Z-score: 318.3 bits: 66.5 E(85289): 5.5e-11
Smith-Waterman score: 450; 43.1% identity (67.7% similar) in 195 aa overlap (90-275:9-193)
60 70 80 90 100 110
pF1KB8 EAAAPGLPELRAELGRAPSPAKCASAFPAAPAFYP---RAYSDPDPAKDPRAEKKELCAL
: : : .. . : .: ... : :
XP_006 MIFSATSPPKFSPTLLHGLAAGAPPQDSSSKSPEPSAD
10 20 30
120 130 140 150 160 170
pF1KB8 QKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLK
.. . ..: . ... : ..:: :::::.::.:::::::.::::::::::..:::...
XP_006 ESPDNDKETPGGGGD---AGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIR
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB8 LTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAP
:: :::::::::.::: :: : .. .:.. :: : ::.:::::::::::: . .:
XP_006 LTPTQVKIWFQNHRYKMKRARAEKGMEVTPLPSP-----RRVAVPVLVRDGKPCHALKAQ
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB8 --YAPAYGVGLNPYGYNA----YPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANN
: .. .:. .:.: . : . ..: .: : .:.:
XP_006 DLAAATFQAGIPFSAYSAQSLQHMQYNAQYSSASTPQYP--TAHPLVQAQQWTW
160 170 180 190 200
300 310 320
pF1KB8 NFVNFGVGDLNAVQSPGIPQSNSGVSTLHGIRAW
>>NP_055175 (OMIM: 603245) homeobox protein Nkx-2.8 [Hom (239 aa)
initn: 470 init1: 318 opt: 433 Z-score: 306.2 bits: 64.5 E(85289): 2.6e-10
Smith-Waterman score: 480; 41.0% identity (55.4% similar) in 249 aa overlap (59-289:18-238)
30 40 50 60 70 80
pF1KB8 AAGELSARLEATLAPSSCMLAAFKPEAYAGPEAAAPGLPELRAELGRAPSPAKCASAFPA
:: : ::. . : :::.: ::. . .
NP_055 MATSGRLSFTVRSLLDLPEQDAQHLPRREPE-PRAPQPDPCAAWLDS
10 20 30 40
90 100 110 120 130
pF1KB8 APAFYPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEADNAERPRAR---------RRR
. :: :: . :: . :...:: :: .:.
NP_055 ERGHYPS--SDESS-------------------LETSPPDSSQRPSARPASPGSDAEKRK
50 60 70 80
140 150 160 170 180 190
pF1KB8 KPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQD
: :::::.::. ::::::.::::::::::.::::.:.:: :::::::::.::: :: :
NP_055 KRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAP
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB8 QTLELVGLPPPP-----PPPARRIAVPVLVRDGKPCLG----DSAPYAPAYGVGLNPYGY
. : : : ::..::::::::.:: : . . : : : .
NP_055 GAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGAPPAAA
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB8 NAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGIPQ
:.::..: :: : . .:: :.:: .. :
NP_055 CPLPGYPAFG-----PG-SALGLFPAYQHLASPALVSWNW
210 220 230
320
pF1KB8 SNSGVSTLHGIRAW
324 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:47:54 2016 done: Sat Nov 5 00:47:55 2016
Total Scan time: 6.970 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]