Result of FASTA (omim) for pF1KB8307
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8307, 118 aa
  1>>>pF1KB8307 118 - 118 aa - 118 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3820+/-0.000417; mu= 4.0591+/- 0.025
 mean_var=177.3027+/-39.801, 0's: 0 Z-trim(116.1): 492  B-trim: 649 in 1/50
 Lambda= 0.096320
 statistics sampled from 26356 (27058) to 26356 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.317), width:  16
 Scan time:  4.760

The best scores are:                                      opt bits E(85289)
NP_665807 (OMIM: 606484) myotrophin [Homo sapiens] ( 118)  787 120.8 5.1e-28
XP_016861517 (OMIM: 611122) PREDICTED: serine/thre ( 687)  225 43.7 0.00048
XP_011531843 (OMIM: 611122) PREDICTED: serine/thre (1027)  225 43.9 0.00062
NP_056014 (OMIM: 611122) serine/threonine-protein  (1053)  225 43.9 0.00063
XP_005265053 (OMIM: 611122) PREDICTED: serine/thre (1083)  225 44.0 0.00064
XP_011531842 (OMIM: 611122) PREDICTED: serine/thre (1086)  225 44.0 0.00064
XP_011531845 (OMIM: 611122) PREDICTED: serine/thre (1019)  224 43.8 0.00068
XP_016872190 (OMIM: 607128) PREDICTED: tankyrase-2 ( 506)  216 42.3 0.00095
XP_016860103 (OMIM: 114480,601593) PREDICTED: BRCA ( 675)  217 42.6   0.001
NP_001269472 (OMIM: 114480,601593) BRCA1-associate ( 758)  217 42.6  0.0011
NP_000456 (OMIM: 114480,601593) BRCA1-associated R ( 777)  217 42.7  0.0011
XP_016860102 (OMIM: 114480,601593) PREDICTED: BRCA ( 810)  217 42.7  0.0012
XP_016865167 (OMIM: 605787) PREDICTED: ankyrin rep ( 152)  205 40.1  0.0013
XP_011538517 (OMIM: 607128) PREDICTED: tankyrase-2 ( 695)  212 41.9  0.0017
XP_005248617 (OMIM: 605787) PREDICTED: ankyrin rep ( 245)  205 40.4  0.0018
NP_066956 (OMIM: 180435,601518) 2-5A-dependent rib ( 741)  211 41.8  0.0019
NP_075526 (OMIM: 605787) ankyrin repeat family A p ( 313)  205 40.5   0.002
NP_065789 (OMIM: 615759) kinase D-interacting subs (1771)  216 43.0  0.0021
XP_016872189 (OMIM: 607128) PREDICTED: tankyrase-2 ( 977)  212 42.1  0.0021
XP_016872188 (OMIM: 607128) PREDICTED: tankyrase-2 (1059)  212 42.1  0.0022
XP_016872187 (OMIM: 607128) PREDICTED: tankyrase-2 (1062)  212 42.1  0.0022
XP_016872186 (OMIM: 607128) PREDICTED: tankyrase-2 (1062)  212 42.1  0.0022
NP_079511 (OMIM: 607128) tankyrase-2 [Homo sapiens (1166)  212 42.2  0.0023
XP_016872185 (OMIM: 607128) PREDICTED: tankyrase-2 (1169)  212 42.2  0.0023
XP_011538515 (OMIM: 607128) PREDICTED: tankyrase-2 (1187)  212 42.2  0.0024
XP_005270242 (OMIM: 607128) PREDICTED: tankyrase-2 (1190)  212 42.2  0.0024
XP_011542149 (OMIM: 603303) PREDICTED: tankyrase-1 (1223)  210 41.9  0.0029
XP_011542148 (OMIM: 603303) PREDICTED: tankyrase-1 (1301)  210 42.0   0.003
XP_006716326 (OMIM: 603303) PREDICTED: tankyrase-1 (1316)  210 42.0  0.0031
XP_011542147 (OMIM: 603303) PREDICTED: tankyrase-1 (1316)  210 42.0  0.0031
NP_003738 (OMIM: 603303) tankyrase-1 [Homo sapiens (1327)  210 42.0  0.0031
NP_001139381 (OMIM: 611397) protein TANC1 isoform  (1390)  210 42.0  0.0032
XP_011510364 (OMIM: 611397) PREDICTED: protein TAN (1554)  210 42.1  0.0034
XP_016860646 (OMIM: 611397) PREDICTED: protein TAN (1660)  210 42.1  0.0035
XP_006712877 (OMIM: 611397) PREDICTED: protein TAN (1677)  210 42.1  0.0035
XP_016860645 (OMIM: 611397) PREDICTED: protein TAN (1685)  210 42.1  0.0036
XP_011510361 (OMIM: 611397) PREDICTED: protein TAN (1697)  210 42.1  0.0036
XP_016860644 (OMIM: 611397) PREDICTED: protein TAN (1738)  210 42.1  0.0036
XP_011510360 (OMIM: 611397) PREDICTED: protein TAN (1755)  210 42.1  0.0036
XP_016860642 (OMIM: 611397) PREDICTED: protein TAN (1773)  210 42.1  0.0037
XP_016860643 (OMIM: 611397) PREDICTED: protein TAN (1773)  210 42.1  0.0037
XP_016860641 (OMIM: 611397) PREDICTED: protein TAN (1790)  210 42.2  0.0037
XP_016860640 (OMIM: 611397) PREDICTED: protein TAN (1791)  210 42.2  0.0037
XP_006712875 (OMIM: 611397) PREDICTED: protein TAN (1826)  210 42.2  0.0037
XP_016860639 (OMIM: 611397) PREDICTED: protein TAN (1838)  210 42.2  0.0037
XP_016860638 (OMIM: 611397) PREDICTED: protein TAN (1844)  210 42.2  0.0038
XP_011510357 (OMIM: 611397) PREDICTED: protein TAN (1853)  210 42.2  0.0038
XP_016860637 (OMIM: 611397) PREDICTED: protein TAN (1854)  210 42.2  0.0038
XP_016860636 (OMIM: 611397) PREDICTED: protein TAN (1854)  210 42.2  0.0038
XP_006712873 (OMIM: 611397) PREDICTED: protein TAN (1861)  210 42.2  0.0038


>>NP_665807 (OMIM: 606484) myotrophin [Homo sapiens]      (118 aa)
 initn: 787 init1: 787 opt: 787  Z-score: 624.1  bits: 120.8 E(85289): 5.1e-28
Smith-Waterman score: 787; 100.0% identity (100.0% similar) in 118 aa overlap (1-118:1-118)

               10        20        30        40        50        60
pF1KB8 MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGAD
               10        20        30        40        50        60

               70        80        90       100       110        
pF1KB8 INAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEATDNQAIKALLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 INAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEATDNQAIKALLQ
               70        80        90       100       110        

>>XP_016861517 (OMIM: 611122) PREDICTED: serine/threonin  (687 aa)
 initn: 628 init1: 210 opt: 225  Z-score: 193.6  bits: 43.7 E(85289): 0.00048
Smith-Waterman score: 225; 40.0% identity (66.4% similar) in 110 aa overlap (6-114:45-154)

                                        10        20        30     
pF1KB8                          MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGG
                                     .. :. ::: :::.  . : ::::   .  
XP_016 ESPAFISKLPQENKSLHSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEK
           20        30        40        50        60        70    

          40        50        60        70        80        90     
pF1KB8 RKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKT
       : ::: ::  :. ::.:.:.:.:: .:: :.. .:::  ::       :..::...:: .
XP_016 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN
           80        90       100       110       120       130    

         100        110                                            
pF1KB8 VKGPDGLTAFE-ATDNQAIKALLQ                                    
       ..  .  : .. :. :.:.:                                        
XP_016 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLS
          140       150       160       170       180       190    

>>XP_011531843 (OMIM: 611122) PREDICTED: serine/threonin  (1027 aa)
 initn: 628 init1: 210 opt: 225  Z-score: 191.6  bits: 43.9 E(85289): 0.00062
Smith-Waterman score: 225; 40.0% identity (66.4% similar) in 110 aa overlap (6-114:45-154)

                                        10        20        30     
pF1KB8                          MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGG
                                     .. :. ::: :::.  . : ::::   .  
XP_011 ESPAFISKLPQENKSLHSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEK
           20        30        40        50        60        70    

          40        50        60        70        80        90     
pF1KB8 RKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKT
       : ::: ::  :. ::.:.:.:.:: .:: :.. .:::  ::       :..::...:: .
XP_011 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN
           80        90       100       110       120       130    

         100        110                                            
pF1KB8 VKGPDGLTAFE-ATDNQAIKALLQ                                    
       ..  .  : .. :. :.:.:                                        
XP_011 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLS
          140       150       160       170       180       190    

>>NP_056014 (OMIM: 611122) serine/threonine-protein phos  (1053 aa)
 initn: 628 init1: 210 opt: 225  Z-score: 191.5  bits: 43.9 E(85289): 0.00063
Smith-Waterman score: 225; 40.0% identity (66.4% similar) in 110 aa overlap (6-114:12-121)

                     10        20        30        40        50    
pF1KB8       MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFL
                  .. :. ::: :::.  . : ::::   .  : ::: ::  :. ::.:.:
NP_056 MAFLKLRDQPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELL
               10        20        30        40        50        60

           60        70        80        90       100        110   
pF1KB8 LLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFE-ATDNQAI
       .:.:: .:: :.. .:::  ::       :..::...:: ...  .  : .. :. :.:.
NP_056 ILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAV
               70        80        90       100       110       120

                                                                   
pF1KB8 KALLQ                                                       
       :                                                           
NP_056 KCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWA
              130       140       150       160       170       180

>>XP_005265053 (OMIM: 611122) PREDICTED: serine/threonin  (1083 aa)
 initn: 628 init1: 210 opt: 225  Z-score: 191.4  bits: 44.0 E(85289): 0.00064
Smith-Waterman score: 225; 40.0% identity (66.4% similar) in 110 aa overlap (6-114:42-151)

                                        10        20        30     
pF1KB8                          MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGG
                                     .. :. ::: :::.  . : ::::   .  
XP_005 VEDESPAFISKLPQENKSLHSPPSGNVLPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEK
              20        30        40        50        60        70 

          40        50        60        70        80        90     
pF1KB8 RKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKT
       : ::: ::  :. ::.:.:.:.:: .:: :.. .:::  ::       :..::...:: .
XP_005 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN
              80        90       100       110       120       130 

         100        110                                            
pF1KB8 VKGPDGLTAFE-ATDNQAIKALLQ                                    
       ..  .  : .. :. :.:.:                                        
XP_005 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLS
             140       150       160       170       180       190 

>>XP_011531842 (OMIM: 611122) PREDICTED: serine/threonin  (1086 aa)
 initn: 628 init1: 210 opt: 225  Z-score: 191.4  bits: 44.0 E(85289): 0.00064
Smith-Waterman score: 225; 40.0% identity (66.4% similar) in 110 aa overlap (6-114:45-154)

                                        10        20        30     
pF1KB8                          MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGG
                                     .. :. ::: :::.  . : ::::   .  
XP_011 ESPAFISKLPQENKSLHSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEK
           20        30        40        50        60        70    

          40        50        60        70        80        90     
pF1KB8 RKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKT
       : ::: ::  :. ::.:.:.:.:: .:: :.. .:::  ::       :..::...:: .
XP_011 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN
           80        90       100       110       120       130    

         100        110                                            
pF1KB8 VKGPDGLTAFE-ATDNQAIKALLQ                                    
       ..  .  : .. :. :.:.:                                        
XP_011 ARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLS
          140       150       160       170       180       190    

>>XP_011531845 (OMIM: 611122) PREDICTED: serine/threonin  (1019 aa)
 initn: 525 init1: 191 opt: 224  Z-score: 190.9  bits: 43.8 E(85289): 0.00068
Smith-Waterman score: 231; 44.1% identity (64.0% similar) in 111 aa overlap (6-113:45-143)

                                        10        20        30     
pF1KB8                          MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGG
                                     .. :. ::: :::.  . : ::::   .  
XP_011 ESPAFISKLPQENKSLHSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEK
           20        30        40        50        60        70    

          40        50        60        70        80           90  
pF1KB8 RKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSC---VKLLLSKGA
       : ::: ::  :. ::.:.:.:.:: .:: :.. .:::  ::    .::   ::::::.::
XP_011 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAV----ASCSEMVKLLLSRGA
           80        90       100       110           120       130

            100       110                                          
pF1KB8 DKTVKGPDGLTAFEATDNQAIKALLQ                                  
       .        ..::.  : .::                                       
XP_011 N--------INAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASS
                      140       150       160       170       180  

>>XP_016872190 (OMIM: 607128) PREDICTED: tankyrase-2 iso  (506 aa)
 initn: 420 init1: 193 opt: 216  Z-score: 188.3  bits: 42.3 E(85289): 0.00095
Smith-Waterman score: 216; 38.1% identity (68.6% similar) in 105 aa overlap (13-117:90-193)

                                 10        20        30        40  
pF1KB8                   MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYA
                                     :  : :.  . .: .:.   .::  ::: :
XP_016 TPLHFAAGNRGQRPLASLQTPPAQPGPTGFGRKDVVEYLLQNGANVQARDDGGLIPLHNA
      60        70        80        90       100       110         

             50        60        70        80        90       100  
pF1KB8 ADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGL
        . :. :....:: .::: :: :. . :::  :. .:...   .::..::. :... :: 
XP_016 CSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGR
     120       130       140       150       160       170         

            110                                                    
pF1KB8 TAFEATDNQAIKALLQ                                            
       ::.. .: .: ::.:                                             
XP_016 TALDLADPSA-KAVLTGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHL
     180        190       200       210       220       230        

>>XP_016860103 (OMIM: 114480,601593) PREDICTED: BRCA1-as  (675 aa)
 initn: 217 init1: 217 opt: 217  Z-score: 187.6  bits: 42.6 E(85289): 0.001
Smith-Waterman score: 217; 37.1% identity (68.6% similar) in 105 aa overlap (13-117:472-576)

                                 10        20        30        40  
pF1KB8                   MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYA
                                     ::.  :.  . .: : :   ..:  ::: :
XP_016 SSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEA
             450       460       470       480       490       500 

             50        60        70        80        90       100  
pF1KB8 ADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGL
        . :.:...:.:: . : .:.   .. .:: .:. .:::. :::::: ::.... .  ::
XP_016 CNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGL
             510       520       530       540       550       560 

            110                                                    
pF1KB8 TAFEATDNQAIKALLQ                                            
          . ::....:.::                                             
XP_016 RPVDYTDDESMKSLLLLPEKNESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSEL
             570       580       590       600       610       620 

>>NP_001269472 (OMIM: 114480,601593) BRCA1-associated RI  (758 aa)
 initn: 217 init1: 217 opt: 217  Z-score: 187.1  bits: 42.6 E(85289): 0.0011
Smith-Waterman score: 217; 37.1% identity (68.6% similar) in 105 aa overlap (13-117:420-524)

                                 10        20        30        40  
pF1KB8                   MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYA
                                     ::.  :.  . .: : :   ..:  ::: :
NP_001 SSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEA
     390       400       410       420       430       440         

             50        60        70        80        90       100  
pF1KB8 ADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGL
        . :.:...:.:: . : .:.   .. .:: .:. .:::. :::::: ::.... .  ::
NP_001 CNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGL
     450       460       470       480       490       500         

            110                                                    
pF1KB8 TAFEATDNQAIKALLQ                                            
          . ::....:.::                                             
NP_001 RPVDYTDDESMKSLLLLPEKNESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSEL
     510       520       530       540       550       560         




118 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 02:08:15 2016 done: Sat Nov  5 02:08:15 2016
 Total Scan time:  4.760 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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