Result of FASTA (omim) for pF1KA0460
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0460, 1424 aa
  1>>>pF1KA0460 1424 - 1424 aa - 1424 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 15.9347+/-0.000504; mu= -26.2106+/- 0.031
 mean_var=666.2414+/-139.245, 0's: 0 Z-trim(123.3): 56  B-trim: 1443 in 1/61
 Lambda= 0.049689
 statistics sampled from 42885 (42952) to 42885 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.504), width:  16
 Scan time: 18.960

The best scores are:                                      opt bits E(85289)
NP_056018 (OMIM: 614695) regulation of nuclear pre (1461) 9503 697.6 1.8e-199
XP_016856253 (OMIM: 614695) PREDICTED: regulation  (1325) 8823 648.8 7.8e-185
NP_001284603 (OMIM: 614695) regulation of nuclear  (1435) 8620 634.3  2e-180
XP_016856252 (OMIM: 614695) PREDICTED: regulation  (1368) 6358 472.1 1.2e-131
XP_011507646 (OMIM: 614695) PREDICTED: regulation  (1394) 6358 472.1 1.3e-131
XP_006711303 (OMIM: 614695) PREDICTED: regulation  ( 960) 5779 430.5 2.9e-119
NP_001284602 (OMIM: 614695) regulation of nuclear  ( 934) 4896 367.2 3.3e-100
XP_005245090 (OMIM: 614695) PREDICTED: regulation  ( 706) 4087 309.1 7.5e-83
XP_016856255 (OMIM: 614695) PREDICTED: regulation  ( 680) 3204 245.8 8.3e-64
XP_016856254 (OMIM: 614695) PREDICTED: regulation  ( 893) 2882 222.8 9.1e-57
XP_016856256 (OMIM: 614695) PREDICTED: regulation  ( 613) 1964 156.9 4.4e-37


>>NP_056018 (OMIM: 614695) regulation of nuclear pre-mRN  (1461 aa)
 initn: 9503 init1: 9503 opt: 9503  Z-score: 3702.2  bits: 697.6 E(85289): 1.8e-199
Smith-Waterman score: 9503; 100.0% identity (100.0% similar) in 1424 aa overlap (1-1424:38-1461)

                                             10        20        30
pF1KA0                               MESIQGLSSWCIENKKHHSTIVYHWMKWLR
                                     ::::::::::::::::::::::::::::::
NP_056 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
        10        20        30        40        50        60       

               40        50        60        70        80        90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
        70        80        90       100       110       120       

              100       110       120       130       140       150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       130       140       150       160       170       180       

              160       170       180       190       200       210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       190       200       210       220       230       240       

              220       230       240       250       260       270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       250       260       270       280       290       300       

              280       290       300       310       320       330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       310       320       330       340       350       360       

              340       350       360       370       380       390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       370       380       390       400       410       420       

              400       410       420       430       440       450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       430       440       450       460       470       480       

              460       470       480       490       500       510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
       490       500       510       520       530       540       

              520       530       540       550       560       570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       550       560       570       580       590       600       

              580       590       600       610       620       630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       610       620       630       640       650       660       

              640       650       660       670       680       690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
       670       680       690       700       710       720       

              700       710       720       730       740       750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
       730       740       750       760       770       780       

              760       770       780       790       800       810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
       790       800       810       820       830       840       

              820       830       840       850       860       870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
       850       860       870       880       890       900       

              880       890       900       910       920       930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
       910       920       930       940       950       960       

              940       950       960       970       980       990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
       970       980       990      1000      1010      1020       

             1000      1010      1020      1030      1040      1050
pF1KA0 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
      1030      1040      1050      1060      1070      1080       

             1060      1070      1080      1090      1100      1110
pF1KA0 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
      1090      1100      1110      1120      1130      1140       

             1120      1130      1140      1150      1160      1170
pF1KA0 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
      1150      1160      1170      1180      1190      1200       

             1180      1190      1200      1210      1220      1230
pF1KA0 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
      1210      1220      1230      1240      1250      1260       

             1240      1250      1260      1270      1280      1290
pF1KA0 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
      1270      1280      1290      1300      1310      1320       

             1300      1310      1320      1330      1340      1350
pF1KA0 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
      1330      1340      1350      1360      1370      1380       

             1360      1370      1380      1390      1400      1410
pF1KA0 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
      1390      1400      1410      1420      1430      1440       

             1420    
pF1KA0 PFFAPKRPFFPPRY
       ::::::::::::::
NP_056 PFFAPKRPFFPPRY
      1450      1460 

>>XP_016856253 (OMIM: 614695) PREDICTED: regulation of n  (1325 aa)
 initn: 8823 init1: 8823 opt: 8823  Z-score: 3439.3  bits: 648.8 E(85289): 7.8e-185
Smith-Waterman score: 8823; 100.0% identity (100.0% similar) in 1325 aa overlap (100-1424:1-1325)

      70        80        90       100       110       120         
pF1KA0 AAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQ
                                     ::::::::::::::::::::::::::::::
XP_016                               MIVALREALSTTFKTQKQLKENLNKQPNKQ
                                             10        20        30

     130       140       150       160       170       180         
pF1KA0 WKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTET
               40        50        60        70        80        90

     190       200       210       220       230       240         
pF1KA0 LKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVK
              100       110       120       130       140       150

     250       260       270       280       290       300         
pF1KA0 VVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEES
              160       170       180       190       200       210

     310       320       330       340       350       360         
pF1KA0 QSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKP
              220       230       240       250       260       270

     370       380       390       400       410       420         
pF1KA0 TENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSV
              280       290       300       310       320       330

     430       440       450       460       470       480         
pF1KA0 MKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALS
              340       350       360       370       380       390

     490       500       510       520       530       540         
pF1KA0 KTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFI
              400       410       420       430       440       450

     550       560       570       580       590       600         
pF1KA0 PKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEV
              460       470       480       490       500       510

     610       620       630       640       650       660         
pF1KA0 TICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPS
              520       530       540       550       560       570

     670       680       690       700       710       720         
pF1KA0 DFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSS
              580       590       600       610       620       630

     730       740       750       760       770       780         
pF1KA0 TRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTS
              640       650       660       670       680       690

     790       800       810       820       830       840         
pF1KA0 FQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVK
              700       710       720       730       740       750

     850       860       870       880       890       900         
pF1KA0 SAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNS
              760       770       780       790       800       810

     910       920       930       940       950       960         
pF1KA0 LSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTST
              820       830       840       850       860       870

     970       980       990      1000      1010      1020         
pF1KA0 IEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETR
              880       890       900       910       920       930

    1030      1040      1050      1060      1070      1080         
pF1KA0 VSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRV
              940       950       960       970       980       990

    1090      1100      1110      1120      1130      1140         
pF1KA0 GWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSF
             1000      1010      1020      1030      1040      1050

    1150      1160      1170      1180      1190      1200         
pF1KA0 NSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTK
             1060      1070      1080      1090      1100      1110

    1210      1220      1230      1240      1250      1260         
pF1KA0 EAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVP
             1120      1130      1140      1150      1160      1170

    1270      1280      1290      1300      1310      1320         
pF1KA0 FPAPPLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPAPPLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVR
             1180      1190      1200      1210      1220      1230

    1330      1340      1350      1360      1370      1380         
pF1KA0 ESLTLPSHSLEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESLTLPSHSLEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREP
             1240      1250      1260      1270      1280      1290

    1390      1400      1410      1420    
pF1KA0 FLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY
       :::::::::::::::::::::::::::::::::::
XP_016 FLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY
             1300      1310      1320     

>>NP_001284603 (OMIM: 614695) regulation of nuclear pre-  (1435 aa)
 initn: 8604 init1: 8604 opt: 8620  Z-score: 3360.2  bits: 634.3 E(85289): 2e-180
Smith-Waterman score: 9269; 98.2% identity (98.2% similar) in 1424 aa overlap (1-1424:38-1435)

                                             10        20        30
pF1KA0                               MESIQGLSSWCIENKKHHSTIVYHWMKWLR
                                     ::::::::::::::::::::::::::::::
NP_001 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
        10        20        30        40        50        60       

               40        50        60        70        80        90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
        70        80        90       100       110       120       

              100       110       120       130       140       150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       ::::::::::::::::::                          ::::::::::::::::
NP_001 EDRNVYPEEMIVALREAL--------------------------TSTNPKAALKSKIVAE
       130       140                                 150       160 

              160       170       180       190       200       210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
             170       180       190       200       210       220 

              220       230       240       250       260       270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
             230       240       250       260       270       280 

              280       290       300       310       320       330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
             290       300       310       320       330       340 

              340       350       360       370       380       390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
             350       360       370       380       390       400 

              400       410       420       430       440       450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
             410       420       430       440       450       460 

              460       470       480       490       500       510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
             470       480       490       500       510       520 

              520       530       540       550       560       570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
             530       540       550       560       570       580 

              580       590       600       610       620       630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
             590       600       610       620       630       640 

              640       650       660       670       680       690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
             650       660       670       680       690       700 

              700       710       720       730       740       750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
             710       720       730       740       750       760 

              760       770       780       790       800       810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
             770       780       790       800       810       820 

              820       830       840       850       860       870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
             830       840       850       860       870       880 

              880       890       900       910       920       930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
             890       900       910       920       930       940 

              940       950       960       970       980       990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
             950       960       970       980       990      1000 

             1000      1010      1020      1030      1040      1050
pF1KA0 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
            1010      1020      1030      1040      1050      1060 

             1060      1070      1080      1090      1100      1110
pF1KA0 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
            1070      1080      1090      1100      1110      1120 

             1120      1130      1140      1150      1160      1170
pF1KA0 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
            1130      1140      1150      1160      1170      1180 

             1180      1190      1200      1210      1220      1230
pF1KA0 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
            1190      1200      1210      1220      1230      1240 

             1240      1250      1260      1270      1280      1290
pF1KA0 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
            1250      1260      1270      1280      1290      1300 

             1300      1310      1320      1330      1340      1350
pF1KA0 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
            1310      1320      1330      1340      1350      1360 

             1360      1370      1380      1390      1400      1410
pF1KA0 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
            1370      1380      1390      1400      1410      1420 

             1420    
pF1KA0 PFFAPKRPFFPPRY
       ::::::::::::::
NP_001 PFFAPKRPFFPPRY
            1430     

>>XP_016856252 (OMIM: 614695) PREDICTED: regulation of n  (1368 aa)
 initn: 7023 init1: 6298 opt: 6358  Z-score: 2484.2  bits: 472.1 E(85289): 1.2e-131
Smith-Waterman score: 8707; 93.5% identity (93.5% similar) in 1424 aa overlap (1-1424:38-1368)

                                             10        20        30
pF1KA0                               MESIQGLSSWCIENKKHHSTIVYHWMKWLR
                                     ::::::::::::::::::::::::::::::
XP_016 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
        10        20        30        40        50        60       

               40        50        60        70        80        90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
        70        80        90       100       110       120       

              100       110       120       130       140       150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       ::::::::::::::::::                          ::::::::::::::::
XP_016 EDRNVYPEEMIVALREAL--------------------------TSTNPKAALKSKIVAE
       130       140                                 150       160 

              160       170       180       190       200       210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
             170       180       190       200       210       220 

              220       230       240       250       260       270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
             230       240       250       260       270       280 

              280       290       300       310       320       330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
             290       300       310       320       330       340 

              340       350       360       370       380       390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
             350       360       370       380       390       400 

              400       410       420       430       440       450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_016 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTG----------------
             410       420       430       440                     

              460       470       480       490       500       510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
                                                          :::::::::
XP_016 ---------------------------------------------------LSSLLQSVT
                                                            450    

              520       530       540       550       560       570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
          460       470       480       490       500       510    

              580       590       600       610       620       630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
          520       530       540       550       560       570    

              640       650       660       670       680       690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
          580       590       600       610       620       630    

              700       710       720       730       740       750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
          640       650       660       670       680       690    

              760       770       780       790       800       810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
          700       710       720       730       740       750    

              820       830       840       850       860       870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
          760       770       780       790       800       810    

              880       890       900       910       920       930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
          820       830       840       850       860       870    

              940       950       960       970       980       990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
          880       890       900       910       920       930    

             1000      1010      1020      1030      1040      1050
pF1KA0 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
          940       950       960       970       980       990    

             1060      1070      1080      1090      1100      1110
pF1KA0 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
         1000      1010      1020      1030      1040      1050    

             1120      1130      1140      1150      1160      1170
pF1KA0 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
         1060      1070      1080      1090      1100      1110    

             1180      1190      1200      1210      1220      1230
pF1KA0 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
         1120      1130      1140      1150      1160      1170    

             1240      1250      1260      1270      1280      1290
pF1KA0 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
         1180      1190      1200      1210      1220      1230    

             1300      1310      1320      1330      1340      1350
pF1KA0 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
         1240      1250      1260      1270      1280      1290    

             1360      1370      1380      1390      1400      1410
pF1KA0 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
         1300      1310      1320      1330      1340      1350    

             1420    
pF1KA0 PFFAPKRPFFPPRY
       ::::::::::::::
XP_016 PFFAPKRPFFPPRY
         1360        

>>XP_011507646 (OMIM: 614695) PREDICTED: regulation of n  (1394 aa)
 initn: 6298 init1: 6298 opt: 6358  Z-score: 2484.0  bits: 472.1 E(85289): 1.3e-131
Smith-Waterman score: 8941; 95.3% identity (95.3% similar) in 1424 aa overlap (1-1424:38-1394)

                                             10        20        30
pF1KA0                               MESIQGLSSWCIENKKHHSTIVYHWMKWLR
                                     ::::::::::::::::::::::::::::::
XP_011 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
        10        20        30        40        50        60       

               40        50        60        70        80        90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
        70        80        90       100       110       120       

              100       110       120       130       140       150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       130       140       150       160       170       180       

              160       170       180       190       200       210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       190       200       210       220       230       240       

              220       230       240       250       260       270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       250       260       270       280       290       300       

              280       290       300       310       320       330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       310       320       330       340       350       360       

              340       350       360       370       380       390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       370       380       390       400       410       420       

              400       410       420       430       440       450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_011 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTG----------------
       430       440       450       460       470                 

              460       470       480       490       500       510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
                                                          :::::::::
XP_011 ---------------------------------------------------LSSLLQSVT
                                                                480

              520       530       540       550       560       570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
              490       500       510       520       530       540

              580       590       600       610       620       630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
              550       560       570       580       590       600

              640       650       660       670       680       690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
              610       620       630       640       650       660

              700       710       720       730       740       750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
              670       680       690       700       710       720

              760       770       780       790       800       810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
              730       740       750       760       770       780

              820       830       840       850       860       870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
              790       800       810       820       830       840

              880       890       900       910       920       930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
              850       860       870       880       890       900

              940       950       960       970       980       990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG
              910       920       930       940       950       960

             1000      1010      1020      1030      1040      1050
pF1KA0 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIET
              970       980       990      1000      1010      1020

             1060      1070      1080      1090      1100      1110
pF1KA0 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASE
             1030      1040      1050      1060      1070      1080

             1120      1130      1140      1150      1160      1170
pF1KA0 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQR
             1090      1100      1110      1120      1130      1140

             1180      1190      1200      1210      1220      1230
pF1KA0 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPF
             1150      1160      1170      1180      1190      1200

             1240      1250      1260      1270      1280      1290
pF1KA0 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKD
             1210      1220      1230      1240      1250      1260

             1300      1310      1320      1330      1340      1350
pF1KA0 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGG
             1270      1280      1290      1300      1310      1320

             1360      1370      1380      1390      1400      1410
pF1KA0 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGP
             1330      1340      1350      1360      1370      1380

             1420    
pF1KA0 PFFAPKRPFFPPRY
       ::::::::::::::
XP_011 PFFAPKRPFFPPRY
             1390    

>>XP_006711303 (OMIM: 614695) PREDICTED: regulation of n  (960 aa)
 initn: 5777 init1: 5777 opt: 5779  Z-score: 2262.0  bits: 430.5 E(85289): 2.9e-119
Smith-Waterman score: 5779; 98.0% identity (98.7% similar) in 916 aa overlap (1-916:38-947)

                                             10        20        30
pF1KA0                               MESIQGLSSWCIENKKHHSTIVYHWMKWLR
                                     ::::::::::::::::::::::::::::::
XP_006 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
        10        20        30        40        50        60       

               40        50        60        70        80        90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
        70        80        90       100       110       120       

              100       110       120       130       140       150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       130       140       150       160       170       180       

              160       170       180       190       200       210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       190       200       210       220       230       240       

              220       230       240       250       260       270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       250       260       270       280       290       300       

              280       290       300       310       320       330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       310       320       330       340       350       360       

              340       350       360       370       380       390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       370       380       390       400       410       420       

              400       410       420       430       440       450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       430       440       450       460       470       480       

              460       470       480       490       500       510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
       490       500       510       520       530       540       

              520       530       540       550       560       570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       550       560       570       580       590       600       

              580       590       600       610       620       630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       610       620       630       640       650       660       

              640       650       660       670       680       690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
       670       680       690       700       710       720       

              700       710       720       730       740       750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
       730       740       750       760       770       780       

              760       770       780       790       800       810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
       790       800       810       820       830       840       

              820       830       840       850       860       870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
       850       860       870       880       890       900       

              880       890       900       910       920       930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
       ::::::::::::::::::::::::..      :  .:.: ..   :              
XP_006 SSPGLFGAFSVRGNEPGSDRSPSPKH------PCRSHGSPTHVRRGESPGLHHFHHVDD 
       910       920       930             940       950       960 

              940       950       960       970       980       990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG

>>NP_001284602 (OMIM: 614695) regulation of nuclear pre-  (934 aa)
 initn: 4878 init1: 4878 opt: 4896  Z-score: 1920.1  bits: 367.2 E(85289): 3.3e-100
Smith-Waterman score: 5545; 95.2% identity (95.9% similar) in 916 aa overlap (1-916:38-921)

                                             10        20        30
pF1KA0                               MESIQGLSSWCIENKKHHSTIVYHWMKWLR
                                     ::::::::::::::::::::::::::::::
NP_001 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
        10        20        30        40        50        60       

               40        50        60        70        80        90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
        70        80        90       100       110       120       

              100       110       120       130       140       150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       ::::::::::::::::::                          ::::::::::::::::
NP_001 EDRNVYPEEMIVALREAL--------------------------TSTNPKAALKSKIVAE
       130       140                                 150       160 

              160       170       180       190       200       210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
             170       180       190       200       210       220 

              220       230       240       250       260       270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
             230       240       250       260       270       280 

              280       290       300       310       320       330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
             290       300       310       320       330       340 

              340       350       360       370       380       390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
             350       360       370       380       390       400 

              400       410       420       430       440       450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
             410       420       430       440       450       460 

              460       470       480       490       500       510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
             470       480       490       500       510       520 

              520       530       540       550       560       570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
             530       540       550       560       570       580 

              580       590       600       610       620       630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
             590       600       610       620       630       640 

              640       650       660       670       680       690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
             650       660       670       680       690       700 

              700       710       720       730       740       750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
             710       720       730       740       750       760 

              760       770       780       790       800       810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
             770       780       790       800       810       820 

              820       830       840       850       860       870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
             830       840       850       860       870       880 

              880       890       900       910       920       930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
       ::::::::::::::::::::::::..      :  .:.: ..   :              
NP_001 SSPGLFGAFSVRGNEPGSDRSPSPKH------PCRSHGSPTHVRRGESPGLHHFHHVDD 
             890       900             910       920       930     

              940       950       960       970       980       990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG

>>XP_005245090 (OMIM: 614695) PREDICTED: regulation of n  (706 aa)
 initn: 4087 init1: 4087 opt: 4087  Z-score: 1608.4  bits: 309.1 E(85289): 7.5e-83
Smith-Waterman score: 4087; 99.7% identity (99.8% similar) in 643 aa overlap (1-643:38-680)

                                             10        20        30
pF1KA0                               MESIQGLSSWCIENKKHHSTIVYHWMKWLR
                                     ::::::::::::::::::::::::::::::
XP_005 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
        10        20        30        40        50        60       

               40        50        60        70        80        90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
        70        80        90       100       110       120       

              100       110       120       130       140       150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       130       140       150       160       170       180       

              160       170       180       190       200       210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       190       200       210       220       230       240       

              220       230       240       250       260       270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       250       260       270       280       290       300       

              280       290       300       310       320       330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       310       320       330       340       350       360       

              340       350       360       370       380       390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       370       380       390       400       410       420       

              400       410       420       430       440       450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       430       440       450       460       470       480       

              460       470       480       490       500       510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
       490       500       510       520       530       540       

              520       530       540       550       560       570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       550       560       570       580       590       600       

              580       590       600       610       620       630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       610       620       630       640       650       660       

              640       650       660       670       680       690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
       :::::::::: .:                                               
XP_005 LEMKIHNFLKEHPCRSHGSPTHVRRGESPGLHHFHHVDD                     
       670       680       690       700                           

>>XP_016856255 (OMIM: 614695) PREDICTED: regulation of n  (680 aa)
 initn: 3910 init1: 3185 opt: 3204  Z-score: 1266.5  bits: 245.8 E(85289): 8.3e-64
Smith-Waterman score: 3853; 95.6% identity (95.8% similar) in 643 aa overlap (1-643:38-654)

                                             10        20        30
pF1KA0                               MESIQGLSSWCIENKKHHSTIVYHWMKWLR
                                     ::::::::::::::::::::::::::::::
XP_016 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
        10        20        30        40        50        60       

               40        50        60        70        80        90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
        70        80        90       100       110       120       

              100       110       120       130       140       150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       ::::::::::::::::::                          ::::::::::::::::
XP_016 EDRNVYPEEMIVALREAL--------------------------TSTNPKAALKSKIVAE
       130       140                                 150       160 

              160       170       180       190       200       210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
             170       180       190       200       210       220 

              220       230       240       250       260       270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
             230       240       250       260       270       280 

              280       290       300       310       320       330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
             290       300       310       320       330       340 

              340       350       360       370       380       390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
             350       360       370       380       390       400 

              400       410       420       430       440       450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
             410       420       430       440       450       460 

              460       470       480       490       500       510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
             470       480       490       500       510       520 

              520       530       540       550       560       570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
             530       540       550       560       570       580 

              580       590       600       610       620       630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
             590       600       610       620       630       640 

              640       650       660       670       680       690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
       :::::::::: .:                                               
XP_016 LEMKIHNFLKEHPCRSHGSPTHVRRGESPGLHHFHHVDD                     
             650       660       670       680                     

>>XP_016856254 (OMIM: 614695) PREDICTED: regulation of n  (893 aa)
 initn: 2919 init1: 2837 opt: 2882  Z-score: 1140.1  bits: 222.8 E(85289): 9.1e-57
Smith-Waterman score: 5217; 90.7% identity (91.4% similar) in 916 aa overlap (1-916:38-880)

                                             10        20        30
pF1KA0                               MESIQGLSSWCIENKKHHSTIVYHWMKWLR
                                     ::::::::::::::::::::::::::::::
XP_016 GSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLR
        10        20        30        40        50        60       

               40        50        60        70        80        90
pF1KA0 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIW
        70        80        90       100       110       120       

              100       110       120       130       140       150
pF1KA0 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAE
       130       140       150       160       170       180       

              160       170       180       190       200       210
pF1KA0 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEAS
       190       200       210       220       230       240       

              220       230       240       250       260       270
pF1KA0 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLD
       250       260       270       280       290       300       

              280       290       300       310       320       330
pF1KA0 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRD
       310       320       330       340       350       360       

              340       350       360       370       380       390
pF1KA0 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATP
       370       380       390       400       410       420       

              400       410       420       430       440       450
pF1KA0 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPS
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_016 PLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTG----------------
       430       440       450       460       470                 

              460       470       480       490       500       510
pF1KA0 NLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVT
                                                          :::::::::
XP_016 ---------------------------------------------------LSSLLQSVT
                                                                480

              520       530       540       550       560       570
pF1KA0 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSAS
              490       500       510       520       530       540

              580       590       600       610       620       630
pF1KA0 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPS
              550       560       570       580       590       600

              640       650       660       670       680       690
pF1KA0 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRD
              610       620       630       640       650       660

              700       710       720       730       740       750
pF1KA0 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVS
              670       680       690       700       710       720

              760       770       780       790       800       810
pF1KA0 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMM
              730       740       750       760       770       780

              820       830       840       850       860       870
pF1KA0 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLS
              790       800       810       820       830       840

              880       890       900       910       920       930
pF1KA0 SSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPH
       ::::::::::::::::::::::::..      :  .:.: ..   :              
XP_016 SSPGLFGAFSVRGNEPGSDRSPSPKH------PCRSHGSPTHVRRGESPGLHHFHHVDD 
              850       860             870       880       890    

              940       950       960       970       980       990
pF1KA0 PVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFG




1424 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 02:38:10 2016 done: Sat Nov  5 02:38:13 2016
 Total Scan time: 18.960 Total Display time:  0.450

Function used was FASTA [36.3.4 Apr, 2011]
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