Result of FASTA (omim) for pF1KA0698
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0698, 891 aa
  1>>>pF1KA0698 891 - 891 aa - 891 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8463+/-0.000457; mu= 17.2429+/- 0.028
 mean_var=65.6150+/-13.207, 0's: 0 Z-trim(109.5): 32  B-trim: 3 in 1/49
 Lambda= 0.158333
 statistics sampled from 17643 (17671) to 17643 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.554), E-opt: 0.2 (0.207), width:  16
 Scan time: 10.530

The best scores are:                                      opt bits E(85289)
NP_055614 (OMIM: 300167) hephaestin isoform b [Hom ( 891) 6141 1412.5       0
XP_006724785 (OMIM: 300167) PREDICTED: hephaestin  (1161) 6141 1412.5       0
NP_620074 (OMIM: 300167) hephaestin isoform a [Hom (1212) 6141 1412.5       0
NP_001124332 (OMIM: 300167) hephaestin isoform c p (1160) 6124 1408.6       0
XP_011529375 (OMIM: 300167) PREDICTED: hephaestin  (1211) 6124 1408.6       0
XP_016885491 (OMIM: 300167) PREDICTED: hephaestin  (1049) 4094 944.9       0
XP_016885490 (OMIM: 300167) PREDICTED: hephaestin  (1050) 4094 944.9       0
XP_016885487 (OMIM: 300167) PREDICTED: hephaestin  (1100) 4094 944.9       0
XP_011529377 (OMIM: 300167) PREDICTED: hephaestin  (1101) 4094 944.9       0
NP_001269070 (OMIM: 300167) hephaestin isoform d p ( 969) 3184 737.0  1e-211
XP_016885488 (OMIM: 300167) PREDICTED: hephaestin  (1090) 3181 736.3 1.8e-211
XP_011529376 (OMIM: 300167) PREDICTED: hephaestin  (1141) 3181 736.3 1.9e-211
XP_016885489 (OMIM: 300167) PREDICTED: hephaestin  (1089) 3164 732.5 2.7e-210
NP_000087 (OMIM: 117700,604290) ceruloplasmin prec (1065) 2417 561.8 6.1e-159
XP_006713564 (OMIM: 117700,604290) PREDICTED: ceru (1065) 2411 560.4 1.6e-158
XP_016861223 (OMIM: 117700,604290) PREDICTED: ceru (1069) 2411 560.4 1.6e-158
XP_006713563 (OMIM: 117700,604290) PREDICTED: ceru (1069) 2411 560.4 1.6e-158
XP_006713562 (OMIM: 117700,604290) PREDICTED: ceru (1090) 2411 560.5 1.6e-158
XP_011510737 (OMIM: 117700,604290) PREDICTED: ceru (1094) 2411 560.5 1.6e-158
XP_016861224 (OMIM: 117700,604290) PREDICTED: ceru (1012) 2181 507.9 9.8e-143
XP_016885492 (OMIM: 300167) PREDICTED: hephaestin  ( 858) 1645 385.5 6.1e-106
XP_016856149 (OMIM: 188055,227400,600880,601367,61 (2087)  889 212.9 1.3e-53
NP_000121 (OMIM: 188055,227400,600880,601367,61230 (2224)  889 212.9 1.4e-53
NP_000123 (OMIM: 134500,300841,306700) coagulation (2351)  637 155.3 3.2e-36


>>NP_055614 (OMIM: 300167) hephaestin isoform b [Homo sa  (891 aa)
 initn: 6141 init1: 6141 opt: 6141  Z-score: 7573.2  bits: 1412.5 E(85289):    0
Smith-Waterman score: 6141; 100.0% identity (100.0% similar) in 891 aa overlap (1-891:1-891)

               10        20        30        40        50        60
pF1KA0 MHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MHAINGFVFGNLPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 ATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 EIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 EEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEDRHLGILGPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 VAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VAKPFEKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 DGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DGKQKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 FSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FSNLPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIM
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYIMAEEVEWDYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QPDNLGTFEIYCQAGSHREAGMRAIYNVSQCPGHQATPRQRYQAARIYYIMAEEVEWDYC
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 PDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRIPRPRTGPEEHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PDRSWEREWHNQSEKDSYGYIFLSNKDGLLGSRYKKAVFREYTDGTFRIPRPRTGPEEHL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 GILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPLAAEPGEVVTYQWNIPER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GILGPLIKGEVGDILTVVFKNNASRPYSVHAHGVLESTTVWPLAAEPGEVVTYQWNIPER
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGGRSDMDREFALLFLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SGPGPNDSACVSWIYYSAVDPIKDMYSGLVGPLAICQKGILEPHGGRSDMDREFALLFLI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 FDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYANLRGLTMYQGERVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FDENKSWYLEENVATHGSQDPGSINLQDETFLESNKMHAINGKLYANLRGLTMYQGERVA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 WYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVEMVASNPGTWLMHCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WYMLAMGQDVDLHTIHFHAESFLYRNGENYRADVVDLFPGTFEVVEMVASNPGTWLMHCH
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 VTDHVHAGMETLFTVFSRTEHLSPLTVITKETEKAVPPRDIEEGNVKMLGMQIPIKNVEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VTDHVHAGMETLFTVFSRTEHLSPLTVITKETEKAVPPRDIEEGNVKMLGMQIPIKNVEM
              790       800       810       820       830       840

              850       860       870       880       890 
pF1KA0 LASVLVAISVTLLLVVLALGGVVWYQHRQRKLRRNRRSILDDSFKLLSFKQ
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LASVLVAISVTLLLVVLALGGVVWYQHRQRKLRRNRRSILDDSFKLLSFKQ
              850       860       870       880       890 

>>XP_006724785 (OMIM: 300167) PREDICTED: hephaestin isof  (1161 aa)
 initn: 6141 init1: 6141 opt: 6141  Z-score: 7571.2  bits: 1412.5 E(85289):    0
Smith-Waterman score: 6141; 100.0% identity (100.0% similar) in 891 aa overlap (1-891:271-1161)

                                             10        20        30
pF1KA0                               MHAINGFVFGNLPELNMCAQKRVAWHLFGM
                                     ::::::::::::::::::::::::::::::
XP_006 SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM
              250       260       270       280       290       300

               40        50        60        70        80        90
pF1KA0 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
              310       320       330       340       350       360

              100       110       120       130       140       150
pF1KA0 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
              370       380       390       400       410       420

              160       170       180       190       200       210
pF1KA0 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
              430       440       450       460       470       480

              220       230       240       250       260       270
pF1KA0 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
              490       500       510       520       530       540

              280       290       300       310       320       330
pF1KA0 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
              550       560       570       580       590       600

              340       350       360       370       380       390
pF1KA0 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
              610       620       630       640       650       660

              400       410       420       430       440       450
pF1KA0 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
              670       680       690       700       710       720

              460       470       480       490       500       510
pF1KA0 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
              730       740       750       760       770       780

              520       530       540       550       560       570
pF1KA0 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
              790       800       810       820       830       840

              580       590       600       610       620       630
pF1KA0 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
              850       860       870       880       890       900

              640       650       660       670       680       690
pF1KA0 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
              910       920       930       940       950       960

              700       710       720       730       740       750
pF1KA0 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
              970       980       990      1000      1010      1020

              760       770       780       790       800       810
pF1KA0 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
             1030      1040      1050      1060      1070      1080

              820       830       840       850       860       870
pF1KA0 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
             1090      1100      1110      1120      1130      1140

              880       890 
pF1KA0 KLRRNRRSILDDSFKLLSFKQ
       :::::::::::::::::::::
XP_006 KLRRNRRSILDDSFKLLSFKQ
             1150      1160 

>--
 initn: 583 init1: 232 opt: 692  Z-score: 844.3  bits: 167.8 E(85289): 2.7e-40
Smith-Waterman score: 692; 41.7% identity (71.4% similar) in 259 aa overlap (100-352:18-270)

      70        80        90       100       110       120         
pF1KA0 PWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPM
                                     :. :  .:  : .: :..  ...::.:.: 
XP_006              MWAMESGHLLWALLFMQSLWP--QLTDGATRVYYLGIRDVQWNYAPK
                            10        20          30        40     

     130       140       150       160       170       180         
pF1KA0 GHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGIL
       :..  :.. : .   ....:......:::::: :. :. ..:... ..  . .   ::.:
XP_006 GRNVITNQPL-DSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDE--VAQPAWLGFL
          50         60        70        80        90         100  

     190       200       210       220       230       240         
pF1KA0 GPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAK----PF
       :::..:::::.: . . : :..:....::::::::: ::..: :::: : : :     : 
XP_006 GPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGP-LKADDSVPPG
            110       120       130       140       150        160 

         250       260       270       280       290       300     
pF1KA0 EKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADG--K
        .  : ::.:   .::  :::::::.: : .:  ::  .::.:::..:. ::: ...  .
XP_006 GSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQ
             170       180       190       200       210       220 

           310       320       330       340       350       360   
pF1KA0 QKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSN
       .. ::..:::::.:.::: ::. : : :.   :   .... : ::.:::           
XP_006 RQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGN
             230       240       250       260       270       280 

           370       380       390       400       410       420   
pF1KA0 LPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPD
                                                                   
XP_006 LPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPW
             290       300       310       320       330       340 

>>NP_620074 (OMIM: 300167) hephaestin isoform a [Homo sa  (1212 aa)
 initn: 6141 init1: 6141 opt: 6141  Z-score: 7570.9  bits: 1412.5 E(85289):    0
Smith-Waterman score: 6141; 100.0% identity (100.0% similar) in 891 aa overlap (1-891:322-1212)

                                             10        20        30
pF1KA0                               MHAINGFVFGNLPELNMCAQKRVAWHLFGM
                                     ::::::::::::::::::::::::::::::
NP_620 SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM
             300       310       320       330       340       350 

               40        50        60        70        80        90
pF1KA0 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
             360       370       380       390       400       410 

              100       110       120       130       140       150
pF1KA0 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
             420       430       440       450       460       470 

              160       170       180       190       200       210
pF1KA0 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
             480       490       500       510       520       530 

              220       230       240       250       260       270
pF1KA0 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
             540       550       560       570       580       590 

              280       290       300       310       320       330
pF1KA0 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
             600       610       620       630       640       650 

              340       350       360       370       380       390
pF1KA0 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
             660       670       680       690       700       710 

              400       410       420       430       440       450
pF1KA0 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
             720       730       740       750       760       770 

              460       470       480       490       500       510
pF1KA0 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
             780       790       800       810       820       830 

              520       530       540       550       560       570
pF1KA0 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
             840       850       860       870       880       890 

              580       590       600       610       620       630
pF1KA0 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
             900       910       920       930       940       950 

              640       650       660       670       680       690
pF1KA0 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
             960       970       980       990      1000      1010 

              700       710       720       730       740       750
pF1KA0 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
            1020      1030      1040      1050      1060      1070 

              760       770       780       790       800       810
pF1KA0 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
            1080      1090      1100      1110      1120      1130 

              820       830       840       850       860       870
pF1KA0 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
            1140      1150      1160      1170      1180      1190 

              880       890 
pF1KA0 KLRRNRRSILDDSFKLLSFKQ
       :::::::::::::::::::::
NP_620 KLRRNRRSILDDSFKLLSFKQ
            1200      1210  

>--
 initn: 606 init1: 232 opt: 692  Z-score: 844.0  bits: 167.8 E(85289): 2.8e-40
Smith-Waterman score: 692; 41.7% identity (71.4% similar) in 259 aa overlap (100-352:69-321)

      70        80        90       100       110       120         
pF1KA0 PWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPM
                                     :. :  .:  : .: :..  ...::.:.: 
NP_620 VSAPSQDLLITKVMWAMESGHLLWALLFMQSLWP--QLTDGATRVYYLGIRDVQWNYAPK
       40        50        60        70          80        90      

     130       140       150       160       170       180         
pF1KA0 GHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGIL
       :..  :.. : .   ....:......:::::: :. :. ..:... ..  . .   ::.:
NP_620 GRNVITNQPL-DSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDE--VAQPAWLGFL
        100        110       120       130       140         150   

     190       200       210       220       230       240         
pF1KA0 GPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAK----PF
       :::..:::::.: . . : :..:....::::::::: ::..: :::: : : :     : 
NP_620 GPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGP-LKADDSVPPG
           160       170       180       190       200        210  

         250       260       270       280       290       300     
pF1KA0 EKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADG--K
        .  : ::.:   .::  :::::::.: : .:  ::  .::.:::..:. ::: ...  .
NP_620 GSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQ
            220       230       240       250       260       270  

           310       320       330       340       350       360   
pF1KA0 QKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSN
       .. ::..:::::.:.::: ::. : : :.   :   .... : ::.:::           
NP_620 RQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGN
            280       290       300       310       320       330  

           370       380       390       400       410       420   
pF1KA0 LPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPD
                                                                   
NP_620 LPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPW
            340       350       360       370       380       390  

>>NP_001124332 (OMIM: 300167) hephaestin isoform c precu  (1160 aa)
 initn: 5661 init1: 5661 opt: 6124  Z-score: 7550.3  bits: 1408.6 E(85289):    0
Smith-Waterman score: 6124; 99.9% identity (99.9% similar) in 891 aa overlap (1-891:271-1160)

                                             10        20        30
pF1KA0                               MHAINGFVFGNLPELNMCAQKRVAWHLFGM
                                     ::::::::::::::::::::::::::::::
NP_001 SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM
              250       260       270       280       290       300

               40        50        60        70        80        90
pF1KA0 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
              310       320       330       340       350       360

              100       110       120       130       140       150
pF1KA0 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
              370       380       390       400       410       420

              160       170       180       190       200       210
pF1KA0 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
              430       440       450       460       470       480

              220       230       240       250       260       270
pF1KA0 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
              490       500       510       520       530       540

              280       290       300       310       320       330
pF1KA0 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
              550       560       570       580       590       600

              340       350       360       370       380       390
pF1KA0 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
              610       620       630       640       650       660

              400       410       420       430       440       450
pF1KA0 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
              670       680       690       700       710       720

              460       470       480       490       500       510
pF1KA0 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
              730       740       750       760       770       780

              520       530       540       550       560       570
pF1KA0 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
              790       800       810       820       830       840

              580       590       600       610       620       630
pF1KA0 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
              850       860       870       880       890       900

              640       650       660       670       680       690
pF1KA0 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
              910       920       930       940       950       960

              700       710       720       730       740       750
pF1KA0 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
              970       980       990      1000      1010      1020

              760       770       780       790       800       810
pF1KA0 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
             1030      1040      1050      1060      1070      1080

              820       830       840       850       860       870
pF1KA0 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETEK-VPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
              1090      1100      1110      1120      1130         

              880       890 
pF1KA0 KLRRNRRSILDDSFKLLSFKQ
       :::::::::::::::::::::
NP_001 KLRRNRRSILDDSFKLLSFKQ
    1140      1150      1160

>--
 initn: 583 init1: 232 opt: 692  Z-score: 844.3  bits: 167.8 E(85289): 2.7e-40
Smith-Waterman score: 692; 41.7% identity (71.4% similar) in 259 aa overlap (100-352:18-270)

      70        80        90       100       110       120         
pF1KA0 PWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPM
                                     :. :  .:  : .: :..  ...::.:.: 
NP_001              MWAMESGHLLWALLFMQSLWP--QLTDGATRVYYLGIRDVQWNYAPK
                            10        20          30        40     

     130       140       150       160       170       180         
pF1KA0 GHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGIL
       :..  :.. : .   ....:......:::::: :. :. ..:... ..  . .   ::.:
NP_001 GRNVITNQPL-DSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDE--VAQPAWLGFL
          50         60        70        80        90         100  

     190       200       210       220       230       240         
pF1KA0 GPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAK----PF
       :::..:::::.: . . : :..:....::::::::: ::..: :::: : : :     : 
NP_001 GPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGP-LKADDSVPPG
            110       120       130       140       150        160 

         250       260       270       280       290       300     
pF1KA0 EKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADG--K
        .  : ::.:   .::  :::::::.: : .:  ::  .::.:::..:. ::: ...  .
NP_001 GSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQ
             170       180       190       200       210       220 

           310       320       330       340       350       360   
pF1KA0 QKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSN
       .. ::..:::::.:.::: ::. : : :.   :   .... : ::.:::           
NP_001 RQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGN
             230       240       250       260       270       280 

           370       380       390       400       410       420   
pF1KA0 LPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPD
                                                                   
NP_001 LPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPW
             290       300       310       320       330       340 

>>XP_011529375 (OMIM: 300167) PREDICTED: hephaestin isof  (1211 aa)
 initn: 5661 init1: 5661 opt: 6124  Z-score: 7550.0  bits: 1408.6 E(85289):    0
Smith-Waterman score: 6124; 99.9% identity (99.9% similar) in 891 aa overlap (1-891:322-1211)

                                             10        20        30
pF1KA0                               MHAINGFVFGNLPELNMCAQKRVAWHLFGM
                                     ::::::::::::::::::::::::::::::
XP_011 SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM
             300       310       320       330       340       350 

               40        50        60        70        80        90
pF1KA0 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
             360       370       380       390       400       410 

              100       110       120       130       140       150
pF1KA0 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
             420       430       440       450       460       470 

              160       170       180       190       200       210
pF1KA0 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
             480       490       500       510       520       530 

              220       230       240       250       260       270
pF1KA0 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
             540       550       560       570       580       590 

              280       290       300       310       320       330
pF1KA0 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
             600       610       620       630       640       650 

              340       350       360       370       380       390
pF1KA0 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
             660       670       680       690       700       710 

              400       410       420       430       440       450
pF1KA0 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
             720       730       740       750       760       770 

              460       470       480       490       500       510
pF1KA0 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
             780       790       800       810       820       830 

              520       530       540       550       560       570
pF1KA0 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
             840       850       860       870       880       890 

              580       590       600       610       620       630
pF1KA0 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
             900       910       920       930       940       950 

              640       650       660       670       680       690
pF1KA0 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
             960       970       980       990      1000      1010 

              700       710       720       730       740       750
pF1KA0 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
            1020      1030      1040      1050      1060      1070 

              760       770       780       790       800       810
pF1KA0 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
            1080      1090      1100      1110      1120      1130 

              820       830       840       850       860       870
pF1KA0 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEK-VPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
             1140      1150      1160      1170      1180      1190

              880       890 
pF1KA0 KLRRNRRSILDDSFKLLSFKQ
       :::::::::::::::::::::
XP_011 KLRRNRRSILDDSFKLLSFKQ
             1200      1210 

>--
 initn: 606 init1: 232 opt: 692  Z-score: 844.0  bits: 167.8 E(85289): 2.8e-40
Smith-Waterman score: 692; 41.7% identity (71.4% similar) in 259 aa overlap (100-352:69-321)

      70        80        90       100       110       120         
pF1KA0 PWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPM
                                     :. :  .:  : .: :..  ...::.:.: 
XP_011 VSAPSQDLLITKVMWAMESGHLLWALLFMQSLWP--QLTDGATRVYYLGIRDVQWNYAPK
       40        50        60        70          80        90      

     130       140       150       160       170       180         
pF1KA0 GHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGIL
       :..  :.. : .   ....:......:::::: :. :. ..:... ..  . .   ::.:
XP_011 GRNVITNQPL-DSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDE--VAQPAWLGFL
        100        110       120       130       140         150   

     190       200       210       220       230       240         
pF1KA0 GPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAK----PF
       :::..:::::.: . . : :..:....::::::::: ::..: :::: : : :     : 
XP_011 GPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGP-LKADDSVPPG
           160       170       180       190       200        210  

         250       260       270       280       290       300     
pF1KA0 EKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADG--K
        .  : ::.:   .::  :::::::.: : .:  ::  .::.:::..:. ::: ...  .
XP_011 GSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQ
            220       230       240       250       260       270  

           310       320       330       340       350       360   
pF1KA0 QKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSN
       .. ::..:::::.:.::: ::. : : :.   :   .... : ::.:::           
XP_011 RQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGN
            280       290       300       310       320       330  

           370       380       390       400       410       420   
pF1KA0 LPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPD
                                                                   
XP_011 LPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPW
            340       350       360       370       380       390  

>>XP_016885491 (OMIM: 300167) PREDICTED: hephaestin isof  (1049 aa)
 initn: 4870 init1: 4094 opt: 4094  Z-score: 5044.9  bits: 944.9 E(85289):    0
Smith-Waterman score: 5115; 87.4% identity (87.4% similar) in 891 aa overlap (1-891:271-1049)

                                             10        20        30
pF1KA0                               MHAINGFVFGNLPELNMCAQKRVAWHLFGM
                                     ::::::::::::::::::::::::::::::
XP_016 SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM
              250       260       270       280       290       300

               40        50        60        70        80        90
pF1KA0 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
              310       320       330       340       350       360

              100       110       120       130       140       150
pF1KA0 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
              370       380       390       400       410       420

              160       170       180       190       200       210
pF1KA0 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
              430       440       450       460       470       480

              220       230       240       250       260       270
pF1KA0 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
              490       500       510       520       530       540

              280       290       300       310       320       330
pF1KA0 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
              550       560       570       580       590       600

              340       350       360       370       380       390
pF1KA0 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
              610       620       630       640       650       660

              400       410       420       430       440       450
pF1KA0 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
              670       680       690       700       710       720

              460       470       480       490       500       510
pF1KA0 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
              730       740       750       760       770       780

              520       530       540       550       560       570
pF1KA0 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
              790       800       810       820       830       840

              580       590       600       610       620       630
pF1KA0 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
       :::::::::::::::::                                           
XP_016 AHGVLESTTVWPLAAEP-------------------------------------------
              850                                                  

              640       650       660       670       680       690
pF1KA0 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
                                                                   
XP_016 ------------------------------------------------------------
                                                                   

              700       710       720       730       740       750
pF1KA0 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------AINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
               860       870       880       890       900         

              760       770       780       790       800       810
pF1KA0 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
     910       920       930       940       950       960         

              820       830       840       850       860       870
pF1KA0 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEK-VPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
     970        980       990      1000      1010      1020        

              880       890 
pF1KA0 KLRRNRRSILDDSFKLLSFKQ
       :::::::::::::::::::::
XP_016 KLRRNRRSILDDSFKLLSFKQ
     1030      1040         

>--
 initn: 583 init1: 232 opt: 692  Z-score: 845.1  bits: 167.8 E(85289): 2.5e-40
Smith-Waterman score: 692; 41.7% identity (71.4% similar) in 259 aa overlap (100-352:18-270)

      70        80        90       100       110       120         
pF1KA0 PWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPM
                                     :. :  .:  : .: :..  ...::.:.: 
XP_016              MWAMESGHLLWALLFMQSLWP--QLTDGATRVYYLGIRDVQWNYAPK
                            10        20          30        40     

     130       140       150       160       170       180         
pF1KA0 GHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGIL
       :..  :.. : .   ....:......:::::: :. :. ..:... ..  . .   ::.:
XP_016 GRNVITNQPL-DSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDE--VAQPAWLGFL
          50         60        70        80        90         100  

     190       200       210       220       230       240         
pF1KA0 GPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAK----PF
       :::..:::::.: . . : :..:....::::::::: ::..: :::: : : :     : 
XP_016 GPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGP-LKADDSVPPG
            110       120       130       140       150        160 

         250       260       270       280       290       300     
pF1KA0 EKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADG--K
        .  : ::.:   .::  :::::::.: : .:  ::  .::.:::..:. ::: ...  .
XP_016 GSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQ
             170       180       190       200       210       220 

           310       320       330       340       350       360   
pF1KA0 QKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSN
       .. ::..:::::.:.::: ::. : : :.   :   .... : ::.:::           
XP_016 RQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGN
             230       240       250       260       270       280 

           370       380       390       400       410       420   
pF1KA0 LPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPD
                                                                   
XP_016 LPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPW
             290       300       310       320       330       340 

>>XP_016885490 (OMIM: 300167) PREDICTED: hephaestin isof  (1050 aa)
 initn: 5350 init1: 4094 opt: 4094  Z-score: 5044.9  bits: 944.9 E(85289):    0
Smith-Waterman score: 5132; 87.5% identity (87.5% similar) in 891 aa overlap (1-891:271-1050)

                                             10        20        30
pF1KA0                               MHAINGFVFGNLPELNMCAQKRVAWHLFGM
                                     ::::::::::::::::::::::::::::::
XP_016 SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM
              250       260       270       280       290       300

               40        50        60        70        80        90
pF1KA0 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
              310       320       330       340       350       360

              100       110       120       130       140       150
pF1KA0 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
              370       380       390       400       410       420

              160       170       180       190       200       210
pF1KA0 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
              430       440       450       460       470       480

              220       230       240       250       260       270
pF1KA0 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
              490       500       510       520       530       540

              280       290       300       310       320       330
pF1KA0 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
              550       560       570       580       590       600

              340       350       360       370       380       390
pF1KA0 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
              610       620       630       640       650       660

              400       410       420       430       440       450
pF1KA0 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
              670       680       690       700       710       720

              460       470       480       490       500       510
pF1KA0 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
              730       740       750       760       770       780

              520       530       540       550       560       570
pF1KA0 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
              790       800       810       820       830       840

              580       590       600       610       620       630
pF1KA0 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
       :::::::::::::::::                                           
XP_016 AHGVLESTTVWPLAAEP-------------------------------------------
              850                                                  

              640       650       660       670       680       690
pF1KA0 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
                                                                   
XP_016 ------------------------------------------------------------
                                                                   

              700       710       720       730       740       750
pF1KA0 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------AINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
               860       870       880       890       900         

              760       770       780       790       800       810
pF1KA0 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
     910       920       930       940       950       960         

              820       830       840       850       860       870
pF1KA0 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
     970       980       990      1000      1010      1020         

              880       890 
pF1KA0 KLRRNRRSILDDSFKLLSFKQ
       :::::::::::::::::::::
XP_016 KLRRNRRSILDDSFKLLSFKQ
    1030      1040      1050

>--
 initn: 583 init1: 232 opt: 692  Z-score: 845.1  bits: 167.8 E(85289): 2.5e-40
Smith-Waterman score: 692; 41.7% identity (71.4% similar) in 259 aa overlap (100-352:18-270)

      70        80        90       100       110       120         
pF1KA0 PWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPM
                                     :. :  .:  : .: :..  ...::.:.: 
XP_016              MWAMESGHLLWALLFMQSLWP--QLTDGATRVYYLGIRDVQWNYAPK
                            10        20          30        40     

     130       140       150       160       170       180         
pF1KA0 GHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGIL
       :..  :.. : .   ....:......:::::: :. :. ..:... ..  . .   ::.:
XP_016 GRNVITNQPL-DSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDE--VAQPAWLGFL
          50         60        70        80        90         100  

     190       200       210       220       230       240         
pF1KA0 GPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAK----PF
       :::..:::::.: . . : :..:....::::::::: ::..: :::: : : :     : 
XP_016 GPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGP-LKADDSVPPG
            110       120       130       140       150        160 

         250       260       270       280       290       300     
pF1KA0 EKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADG--K
        .  : ::.:   .::  :::::::.: : .:  ::  .::.:::..:. ::: ...  .
XP_016 GSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQ
             170       180       190       200       210       220 

           310       320       330       340       350       360   
pF1KA0 QKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSN
       .. ::..:::::.:.::: ::. : : :.   :   .... : ::.:::           
XP_016 RQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGN
             230       240       250       260       270       280 

           370       380       390       400       410       420   
pF1KA0 LPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPD
                                                                   
XP_016 LPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPW
             290       300       310       320       330       340 

>>XP_016885487 (OMIM: 300167) PREDICTED: hephaestin isof  (1100 aa)
 initn: 4870 init1: 4094 opt: 4094  Z-score: 5044.6  bits: 944.9 E(85289):    0
Smith-Waterman score: 5115; 87.4% identity (87.4% similar) in 891 aa overlap (1-891:322-1100)

                                             10        20        30
pF1KA0                               MHAINGFVFGNLPELNMCAQKRVAWHLFGM
                                     ::::::::::::::::::::::::::::::
XP_016 SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM
             300       310       320       330       340       350 

               40        50        60        70        80        90
pF1KA0 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
             360       370       380       390       400       410 

              100       110       120       130       140       150
pF1KA0 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
             420       430       440       450       460       470 

              160       170       180       190       200       210
pF1KA0 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
             480       490       500       510       520       530 

              220       230       240       250       260       270
pF1KA0 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
             540       550       560       570       580       590 

              280       290       300       310       320       330
pF1KA0 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
             600       610       620       630       640       650 

              340       350       360       370       380       390
pF1KA0 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
             660       670       680       690       700       710 

              400       410       420       430       440       450
pF1KA0 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
             720       730       740       750       760       770 

              460       470       480       490       500       510
pF1KA0 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
             780       790       800       810       820       830 

              520       530       540       550       560       570
pF1KA0 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
             840       850       860       870       880       890 

              580       590       600       610       620       630
pF1KA0 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
       :::::::::::::::::                                           
XP_016 AHGVLESTTVWPLAAEP-------------------------------------------
             900                                                   

              640       650       660       670       680       690
pF1KA0 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
                                                                   
XP_016 ------------------------------------------------------------
                                                                   

              700       710       720       730       740       750
pF1KA0 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------AINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
              910       920       930       940       950       960

              760       770       780       790       800       810
pF1KA0 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
              970       980       990      1000      1010      1020

              820       830       840       850       860       870
pF1KA0 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEK-VPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
              1030      1040      1050      1060      1070         

              880       890 
pF1KA0 KLRRNRRSILDDSFKLLSFKQ
       :::::::::::::::::::::
XP_016 KLRRNRRSILDDSFKLLSFKQ
    1080      1090      1100

>--
 initn: 606 init1: 232 opt: 692  Z-score: 844.7  bits: 167.8 E(85289): 2.6e-40
Smith-Waterman score: 692; 41.7% identity (71.4% similar) in 259 aa overlap (100-352:69-321)

      70        80        90       100       110       120         
pF1KA0 PWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPM
                                     :. :  .:  : .: :..  ...::.:.: 
XP_016 VSAPSQDLLITKVMWAMESGHLLWALLFMQSLWP--QLTDGATRVYYLGIRDVQWNYAPK
       40        50        60        70          80        90      

     130       140       150       160       170       180         
pF1KA0 GHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGIL
       :..  :.. : .   ....:......:::::: :. :. ..:... ..  . .   ::.:
XP_016 GRNVITNQPL-DSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDE--VAQPAWLGFL
        100        110       120       130       140         150   

     190       200       210       220       230       240         
pF1KA0 GPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAK----PF
       :::..:::::.: . . : :..:....::::::::: ::..: :::: : : :     : 
XP_016 GPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGP-LKADDSVPPG
           160       170       180       190       200        210  

         250       260       270       280       290       300     
pF1KA0 EKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADG--K
        .  : ::.:   .::  :::::::.: : .:  ::  .::.:::..:. ::: ...  .
XP_016 GSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQ
            220       230       240       250       260       270  

           310       320       330       340       350       360   
pF1KA0 QKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSN
       .. ::..:::::.:.::: ::. : : :.   :   .... : ::.:::           
XP_016 RQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGN
            280       290       300       310       320       330  

           370       380       390       400       410       420   
pF1KA0 LPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPD
                                                                   
XP_016 LPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPW
            340       350       360       370       380       390  

>>XP_011529377 (OMIM: 300167) PREDICTED: hephaestin isof  (1101 aa)
 initn: 5350 init1: 4094 opt: 4094  Z-score: 5044.6  bits: 944.9 E(85289):    0
Smith-Waterman score: 5132; 87.5% identity (87.5% similar) in 891 aa overlap (1-891:322-1101)

                                             10        20        30
pF1KA0                               MHAINGFVFGNLPELNMCAQKRVAWHLFGM
                                     ::::::::::::::::::::::::::::::
XP_011 SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM
             300       310       320       330       340       350 

               40        50        60        70        80        90
pF1KA0 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
             360       370       380       390       400       410 

              100       110       120       130       140       150
pF1KA0 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
             420       430       440       450       460       470 

              160       170       180       190       200       210
pF1KA0 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
             480       490       500       510       520       530 

              220       230       240       250       260       270
pF1KA0 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
             540       550       560       570       580       590 

              280       290       300       310       320       330
pF1KA0 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
             600       610       620       630       640       650 

              340       350       360       370       380       390
pF1KA0 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
             660       670       680       690       700       710 

              400       410       420       430       440       450
pF1KA0 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
             720       730       740       750       760       770 

              460       470       480       490       500       510
pF1KA0 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
             780       790       800       810       820       830 

              520       530       540       550       560       570
pF1KA0 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
             840       850       860       870       880       890 

              580       590       600       610       620       630
pF1KA0 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
       :::::::::::::::::                                           
XP_011 AHGVLESTTVWPLAAEP-------------------------------------------
             900                                                   

              640       650       660       670       680       690
pF1KA0 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
                                                                   
XP_011 ------------------------------------------------------------
                                                                   

              700       710       720       730       740       750
pF1KA0 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 --------AINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
              910       920       930       940       950       960

              760       770       780       790       800       810
pF1KA0 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
              970       980       990      1000      1010      1020

              820       830       840       850       860       870
pF1KA0 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
             1030      1040      1050      1060      1070      1080

              880       890 
pF1KA0 KLRRNRRSILDDSFKLLSFKQ
       :::::::::::::::::::::
XP_011 KLRRNRRSILDDSFKLLSFKQ
             1090      1100 

>--
 initn: 606 init1: 232 opt: 692  Z-score: 844.7  bits: 167.8 E(85289): 2.6e-40
Smith-Waterman score: 692; 41.7% identity (71.4% similar) in 259 aa overlap (100-352:69-321)

      70        80        90       100       110       120         
pF1KA0 PWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPM
                                     :. :  .:  : .: :..  ...::.:.: 
XP_011 VSAPSQDLLITKVMWAMESGHLLWALLFMQSLWP--QLTDGATRVYYLGIRDVQWNYAPK
       40        50        60        70          80        90      

     130       140       150       160       170       180         
pF1KA0 GHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGIL
       :..  :.. : .   ....:......:::::: :. :. ..:... ..  . .   ::.:
XP_011 GRNVITNQPL-DSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDE--VAQPAWLGFL
        100        110       120       130       140         150   

     190       200       210       220       230       240         
pF1KA0 GPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAK----PF
       :::..:::::.: . . : :..:....::::::::: ::..: :::: : : :     : 
XP_011 GPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGP-LKADDSVPPG
           160       170       180       190       200        210  

         250       260       270       280       290       300     
pF1KA0 EKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADG--K
        .  : ::.:   .::  :::::::.: : .:  ::  .::.:::..:. ::: ...  .
XP_011 GSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQ
            220       230       240       250       260       270  

           310       320       330       340       350       360   
pF1KA0 QKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSN
       .. ::..:::::.:.::: ::. : : :.   :   .... : ::.:::           
XP_011 RQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGN
            280       290       300       310       320       330  

           370       380       390       400       410       420   
pF1KA0 LPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPD
                                                                   
XP_011 LPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPW
            340       350       360       370       380       390  

>>NP_001269070 (OMIM: 300167) hephaestin isoform d precu  (969 aa)
 initn: 3605 init1: 3184 opt: 3184  Z-score: 3922.1  bits: 737.0 E(85289): 1e-211
Smith-Waterman score: 4422; 78.5% identity (78.5% similar) in 891 aa overlap (1-891:271-969)

                                             10        20        30
pF1KA0                               MHAINGFVFGNLPELNMCAQKRVAWHLFGM
                                     ::::::::::::::::::::::::::::::
NP_001 SWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGNLPELNMCAQKRVAWHLFGM
              250       260       270       280       290       300

               40        50        60        70        80        90
pF1KA0 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGM
              310       320       330       340       350       360

              100       110       120       130       140       150
pF1KA0 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFF
              370       380       390       400       410       420

              160       170       180       190       200       210
pF1KA0 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGILGPVIRAEVGDTIQVVFYNRAS
              430       440       450       460       470       480

              220       230       240       250       260       270
pF1KA0 QPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAKPFEKVTYRWTVPPHAGPTAQDPACLTW
       ::::::::::::::::::::::::                                    
NP_001 QPFSMQPHGVFYEKDYEGTVYNDG------------------------------------
              490       500                                        

              280       290       300       310       320       330
pF1KA0 MYFSAADPIRDTNSGLVGPLLVCRAGALGADGKQKGVDKEFFLLFTVLDENKSWYSNANQ
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              340       350       360       370       380       390
pF1KA0 AAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSNLPRLDMCKGDTVAWHLLGLGTETDVHG
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              400       410       420       430       440       450
pF1KA0 VMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCQAGSHREAGMRAIYNVSQ
                                           ::::::::::::::::::::::::
NP_001 ------------------------------------TFEIYCQAGSHREAGMRAIYNVSQ
                                              510       520        

              460       470       480       490       500       510
pF1KA0 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPGHQATPRQRYQAARIYYIMAEEVEWDYCPDRSWEREWHNQSEKDSYGYIFLSNKDGLL
      530       540       550       560       570       580        

              520       530       540       550       560       570
pF1KA0 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSRYKKAVFREYTDGTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNASRPYSVH
      590       600       610       620       630       640        

              580       590       600       610       620       630
pF1KA0 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHGVLESTTVWPLAAEPGEVVTYQWNIPERSGPGPNDSACVSWIYYSAVDPIKDMYSGLV
      650       660       670       680       690       700        

              640       650       660       670       680       690
pF1KA0 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPLAICQKGILEPHGGRSDMDREFALLFLIFDENKSWYLEENVATHGSQDPGSINLQDET
      710       720       730       740       750       760        

              700       710       720       730       740       750
pF1KA0 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLESNKMHAINGKLYANLRGLTMYQGERVAWYMLAMGQDVDLHTIHFHAESFLYRNGENY
      770       780       790       800       810       820        

              760       770       780       790       800       810
pF1KA0 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RADVVDLFPGTFEVVEMVASNPGTWLMHCHVTDHVHAGMETLFTVFSRTEHLSPLTVITK
      830       840       850       860       870       880        

              820       830       840       850       860       870
pF1KA0 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETEKAVPPRDIEEGNVKMLGMQIPIKNVEMLASVLVAISVTLLLVVLALGGVVWYQHRQR
      890       900       910       920       930       940        

              880       890 
pF1KA0 KLRRNRRSILDDSFKLLSFKQ
       :::::::::::::::::::::
NP_001 KLRRNRRSILDDSFKLLSFKQ
      950       960         

>--
 initn: 583 init1: 232 opt: 692  Z-score: 845.6  bits: 167.8 E(85289): 2.3e-40
Smith-Waterman score: 692; 41.7% identity (71.4% similar) in 259 aa overlap (100-352:18-270)

      70        80        90       100       110       120         
pF1KA0 PWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPM
                                     :. :  .:  : .: :..  ...::.:.: 
NP_001              MWAMESGHLLWALLFMQSLWP--QLTDGATRVYYLGIRDVQWNYAPK
                            10        20          30        40     

     130       140       150       160       170       180         
pF1KA0 GHDGSTGKNLREPGSISDKFFQKSSSRIGGTYWKVRYEAFQDETFQEKMHLEEDRHLGIL
       :..  :.. : .   ....:......:::::: :. :. ..:... ..  . .   ::.:
NP_001 GRNVITNQPL-DSDIVASSFLKSDKNRIGGTYKKTIYKEYKDDSYTDE--VAQPAWLGFL
          50         60        70        80        90         100  

     190       200       210       220       230       240         
pF1KA0 GPVIRAEVGDTIQVVFYNRASQPFSMQPHGVFYEKDYEGTVYNDGSSYPGLVAK----PF
       :::..:::::.: . . : :..:....::::::::: ::..: :::: : : :     : 
NP_001 GPVLQAEVGDVILIHLKNFATRPYTIHPHGVFYEKDSEGSLYPDGSSGP-LKADDSVPPG
            110       120       130       140       150        160 

         250       260       270       280       290       300     
pF1KA0 EKVTYRWTVPPHAGPTAQDPACLTWMYFSAADPIRDTNSGLVGPLLVCRAGALGADG--K
        .  : ::.:   .::  :::::::.: : .:  ::  .::.:::..:. ::: ...  .
NP_001 GSHIYNWTIPEGHAPTDADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGALDGNSPPQ
             170       180       190       200       210       220 

           310       320       330       340       350       360   
pF1KA0 QKGVDKEFFLLFTVLDENKSWYSNANQAAAMLDFRLLSEDIEGFQDSNRMHAINGFLFSN
       .. ::..:::::.:.::: ::. : : :.   :   .... : ::.:::           
NP_001 RQDVDHDFFLLFSVVDENLSWHLNENIATYCSDPASVDKEDETFQESNRMHAINGFVFGN
             230       240       250       260       270       280 

           370       380       390       400       410       420   
pF1KA0 LPRLDMCKGDTVAWHLLGLGTETDVHGVMFQGNTVQLQGMRKGAAMLFPHTFVMAIMQPD
                                                                   
NP_001 LPELNMCAQKRVAWHLFGMGNEIDVHTAFFHGQMLTTRGHHTDVANIFPATFVTAEMVPW
             290       300       310       320       330       340 




891 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 06:43:30 2016 done: Sat Nov  5 06:43:31 2016
 Total Scan time: 10.530 Total Display time:  0.360

Function used was FASTA [36.3.4 Apr, 2011]
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