Result of FASTA (omim) for pF1KB6563
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6563, 374 aa
  1>>>pF1KB6563 374 - 374 aa - 374 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2880+/-0.000367; mu= 16.4680+/- 0.023
 mean_var=66.3177+/-13.284, 0's: 0 Z-trim(112.9): 89  B-trim: 593 in 1/57
 Lambda= 0.157492
 statistics sampled from 21848 (21947) to 21848 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.257), width:  16
 Scan time:  6.640

The best scores are:                                      opt bits E(85289)
NP_002059 (OMIM: 139314) guanine nucleotide-bindin ( 374) 2502 577.5 1.7e-164
NP_002063 (OMIM: 163000,185300,600998) guanine nuc ( 359) 1229 288.3 1.9e-77
NP_002058 (OMIM: 139313) guanine nucleotide-bindin ( 359) 1218 285.8 1.1e-76
NP_004288 (OMIM: 604397) guanine nucleotide-bindin ( 355) 1188 278.9 1.2e-74
XP_016870117 (OMIM: 163000,185300,600998) PREDICTE ( 301) 1040 245.3 1.4e-64
XP_016870830 (OMIM: 604397) PREDICTED: guanine nuc ( 301)  990 233.9 3.7e-61
NP_002060 (OMIM: 139310) guanine nucleotide-bindin ( 354)  883 209.6 8.8e-54
NP_002061 (OMIM: 139360,192605) guanine nucleotide ( 355)  877 208.3 2.3e-53
NP_006487 (OMIM: 139370,602483) guanine nucleotide ( 354)  874 207.6 3.6e-53
NP_001095856 (OMIM: 139395) guanine nucleotide-bin ( 354)  873 207.4 4.3e-53
NP_000163 (OMIM: 139330,610444,616389) guanine nuc ( 350)  871 206.9 5.8e-53
NP_653082 (OMIM: 139330,610444,616389) guanine nuc ( 350)  871 206.9 5.8e-53
NP_620073 (OMIM: 139311,615473) guanine nucleotide ( 354)  869 206.5   8e-53
XP_011539566 (OMIM: 139340,613856) PREDICTED: guan ( 354)  864 205.3 1.8e-52
NP_005263 (OMIM: 139340,613856) guanine nucleotide ( 354)  864 205.3 1.8e-52
XP_011514426 (OMIM: 139395) PREDICTED: guanine nuc ( 297)  853 202.8 8.6e-52
NP_006563 (OMIM: 604406) guanine nucleotide-bindin ( 377)  847 201.5 2.7e-51
NP_066268 (OMIM: 139311,615473) guanine nucleotide ( 354)  843 200.6 4.8e-51
NP_892023 (OMIM: 139312,615073) guanine nucleotide ( 458)  834 198.6 2.4e-50
NP_002064 (OMIM: 139160) guanine nucleotide-bindin ( 355)  826 196.7   7e-50
NP_001070957 (OMIM: 102200,103580,139320,166350,17 ( 379)  821 195.6 1.6e-49
NP_001248372 (OMIM: 139312,615073) guanine nucleot ( 381)  818 194.9 2.6e-49
NP_001135811 (OMIM: 139312,615073) guanine nucleot ( 381)  818 194.9 2.6e-49
NP_536351 (OMIM: 102200,103580,139320,166350,17480 ( 380)  816 194.4 3.6e-49
NP_001159897 (OMIM: 139360,192605) guanine nucleot ( 318)  810 193.0 7.9e-49
NP_001269548 (OMIM: 139360,192605) guanine nucleot ( 339)  810 193.0 8.4e-49
NP_001269549 (OMIM: 139360,192605) guanine nucleot ( 339)  810 193.0 8.4e-49
NP_031379 (OMIM: 604394) guanine nucleotide-bindin ( 381)  804 191.7 2.4e-48
XP_016883303 (OMIM: 102200,103580,139320,166350,17 (1022)  796 190.1 1.9e-47
XP_016883302 (OMIM: 102200,103580,139320,166350,17 (1023)  791 189.0 4.2e-47
XP_011517526 (OMIM: 604397) PREDICTED: guanine nuc ( 237)  775 185.0 1.5e-46
XP_016883304 (OMIM: 102200,103580,139320,166350,17 ( 347)  760 181.7 2.2e-45
NP_001243343 (OMIM: 139310) guanine nucleotide-bin ( 302)  746 178.5 1.8e-44
NP_001269546 (OMIM: 139360,192605) guanine nucleot ( 303)  743 177.8 2.9e-44
XP_011521305 (OMIM: 139311,615473) PREDICTED: guan ( 312)  718 172.1 1.5e-42
XP_016883308 (OMIM: 102200,103580,139320,166350,17 ( 320)  692 166.2 9.4e-41
XP_016883306 (OMIM: 102200,103580,139320,166350,17 ( 320)  692 166.2 9.4e-41
XP_016883307 (OMIM: 102200,103580,139320,166350,17 ( 320)  692 166.2 9.4e-41
XP_016883305 (OMIM: 102200,103580,139320,166350,17 ( 320)  662 159.4 1.1e-38
XP_016883309 (OMIM: 102200,103580,139320,166350,17 ( 320)  662 159.4 1.1e-38
NP_001296790 (OMIM: 102200,103580,139320,166350,17 ( 335)  660 159.0 1.5e-38
NP_001296769 (OMIM: 102200,103580,139320,166350,17 ( 335)  660 159.0 1.5e-38
NP_000507 (OMIM: 102200,103580,139320,166350,17480 ( 394)  660 159.0 1.7e-38
NP_001070956 (OMIM: 102200,103580,139320,166350,17 ( 395)  660 159.0 1.7e-38
XP_016884275 (OMIM: 139160) PREDICTED: guanine nuc ( 307)  657 158.3 2.2e-38
NP_536350 (OMIM: 102200,103580,139320,166350,17480 (1037)  660 159.2 3.9e-38
XP_016883301 (OMIM: 102200,103580,139320,166350,17 (1038)  660 159.2 3.9e-38
NP_001269547 (OMIM: 139360,192605) guanine nucleot ( 274)  650 156.6 6.1e-38
NP_001269354 (OMIM: 604406) guanine nucleotide-bin ( 282)  625 151.0 3.2e-36
XP_011513590 (OMIM: 604394) PREDICTED: guanine nuc ( 284)  612 148.0 2.5e-35


>>NP_002059 (OMIM: 139314) guanine nucleotide-binding pr  (374 aa)
 initn: 2502 init1: 2502 opt: 2502  Z-score: 3074.3  bits: 577.5 E(85289): 1.7e-164
Smith-Waterman score: 2502; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374)

               10        20        30        40        50        60
pF1KB6 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR
              310       320       330       340       350       360

              370    
pF1KB6 DSVLARYLDEINLL
       ::::::::::::::
NP_002 DSVLARYLDEINLL
              370    

>>NP_002063 (OMIM: 163000,185300,600998) guanine nucleot  (359 aa)
 initn: 1345 init1: 1229 opt: 1229  Z-score: 1511.3  bits: 288.3 E(85289): 1.9e-77
Smith-Waterman score: 1336; 55.8% identity (80.9% similar) in 362 aa overlap (13-374:10-359)

               10        20        30        40        50        60
pF1KB6 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK
                   ::.:. : : :...::.: : ..:.. : :::::::: ::::::::::
NP_002    MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIK
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB6 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD
       :::::::.:::.:...::  :::::::..:.:::.::. :.::..  ..: ::.::   :
NP_002 QMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVD
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KB6 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ
         ::..::. :. :.. :: : ::. ::.::::..: ::. :::. :.:... .:.:: :
NP_002 VEKVSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQ
       120       130       140       150       160       170       

              190       200       210       220       230       240
pF1KB6 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ
       :::: :.::::: :: :..:.. .:.::::::.:::.::::::::: ....:..::::::
NP_002 DVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQ
       180       190       200       210       220       230       

              250       260       270       280       290       300
pF1KB6 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG
        : :...::::.:: ::: ::.  :::...:::::::: :.:::::  :::. ::: ..:
NP_002 VLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDG
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KB6 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR
       :..::.::..::: :.. .      .:...:       ..::.::::::.::: ::  :.
NP_002 PQRDAQAAREFILKMFVDL------NPDSDKI------IYSHFTCATDTENIRFVFAAVK
       300       310             320             330       340     

              370    
pF1KB6 DSVLARYLDEINLL
       :..:   : : ::.
NP_002 DTILQLNLKEYNLV
         350         

>>NP_002058 (OMIM: 139313) guanine nucleotide-binding pr  (359 aa)
 initn: 1334 init1: 1218 opt: 1218  Z-score: 1497.8  bits: 285.8 E(85289): 1.1e-76
Smith-Waterman score: 1325; 55.8% identity (80.4% similar) in 362 aa overlap (13-374:10-359)

               10        20        30        40        50        60
pF1KB6 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK
                   ::... : . :.. ::.. : ..:.. : :::::::: ::::::::::
NP_002    MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIK
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB6 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD
       :::::::::::::...::  :::::::..:.:::.::: :.: ..  ..: .: :.   :
NP_002 QMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVD
        60        70        80        90       100       110       

              130       140       150       160       170       180
pF1KB6 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ
         ::::::..:..:.. ::.: ::. ::.::::..: ::: :::. ..::.  ::.:: :
NP_002 VEKVTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQ
       120       130       140       150       160       170       

              190       200       210       220       230       240
pF1KB6 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ
       :::: :.::::: :: :....  .:.::::::.:::.::::::::: ....:..::::::
NP_002 DVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQ
       180       190       200       210       220       230       

              250       260       270       280       290       300
pF1KB6 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG
        : :...::::.:: ::: ::.  :::...:::::::: :.::.::  :::. ::: :.:
NP_002 VLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDG
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KB6 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR
       :..::.::..::: :.. .      .:...:       ..::.::::::.::: ::  :.
NP_002 PQRDAQAAREFILKMFVDL------NPDSDKI------IYSHFTCATDTENIRFVFAAVK
       300       310             320             330       340     

              370    
pF1KB6 DSVLARYLDEINLL
       :..:   : : ::.
NP_002 DTILQLNLKEYNLV
         350         

>>NP_004288 (OMIM: 604397) guanine nucleotide-binding pr  (355 aa)
 initn: 1290 init1: 1176 opt: 1188  Z-score: 1461.1  bits: 278.9 E(85289): 1.2e-74
Smith-Waterman score: 1289; 54.1% identity (77.9% similar) in 366 aa overlap (9-374:4-355)

               10        20        30        40        50        60
pF1KB6 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK
               ::  ::. .:: . :.. ::.: : ..::. : :::::::: ::::::::::
NP_004      MAGCC--CLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIK
                      10        20        30        40        50   

               70        80        90       100       110       120
pF1KB6 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD
       :::::::.:::.:.::::  :::::::..:.:::.::. :.: .   ..:..:...   .
NP_004 QMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVE
            60        70        80        90       100       110   

              130       140       150       160       170       180
pF1KB6 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ
         ::. . .. . :.. ::.: ::. ::.::::..: ::: :::. ..::.  ..::: :
NP_004 VDKVSMLSREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQ
           120       130       140       150       160       170   

              190       200       210       220       230       240
pF1KB6 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ
       :::: :.::::: :: :....  .:.::::::.:::.:::::::.: ..:.:..::::::
NP_004 DVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQ
           180       190       200       210       220       230   

              250       260       270       280       290       300
pF1KB6 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG
        : : ..::::.:: ::: ::.  ::: ..:::::::: :.:::::  ::: .::: . :
NP_004 VLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTG
           240       250       260       270       280       290   

              310       320       330       340       350       360
pF1KB6 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR
       ::::..::. ::: .:  .      .:.      . . ..::.::::::.::: ::  :.
NP_004 PKQDVRAARDFILKLYQDQ------NPD------KEKVIYSHFTCATDTDNIRFVFAAVK
           300       310                   320       330       340 

              370    
pF1KB6 DSVLARYLDEINLL
       :..:   : :.::.
NP_004 DTILQLNLREFNLV
             350     

>>XP_016870117 (OMIM: 163000,185300,600998) PREDICTED: g  (301 aa)
 initn: 1156 init1: 1040 opt: 1040  Z-score: 1280.4  bits: 245.3 E(85289): 1.4e-64
Smith-Waterman score: 1147; 54.6% identity (80.5% similar) in 313 aa overlap (62-374:1-301)

              40        50        60        70        80        90 
pF1KB6 LLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMR
                                     ::::::.:::.:...::  :::::::..:.
XP_016                               MRIIHGSGYSDEDKRGFTKLVYQNIFTAMQ
                                             10        20        30

             100       110       120       130       140       150 
pF1KB6 AMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERR
       :::.::. :.::..  ..: ::.::   :  ::..::. :. :.. :: : ::. ::.::
XP_016 AMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRR
               40        50        60        70        80        90

             160       170       180       190       200       210 
pF1KB6 REFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGG
       ::..: ::. :::. :.:... .:.:: ::::: :.::::: :: :..:.. .:.:::::
XP_016 REYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGG
              100       110       120       130       140       150

             220       230       240       250       260       270 
pF1KB6 QKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTS
       :.:::.::::::::: ....:..:::::: : :...::::.:: ::: ::.  :::...:
XP_016 QRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSS
              160       170       180       190       200       210

             280       290       300       310       320       330 
pF1KB6 VILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSK
       ::::::: :.:::::  :::. ::: ..::..::.::..::: :.. .      .:...:
XP_016 VILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDL------NPDSDK
              220       230       240       250             260    

             340       350       360       370    
pF1KB6 KGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
              ..::.::::::.::: ::  :.:..:   : : ::.
XP_016 I------IYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
                270       280       290       300 

>>XP_016870830 (OMIM: 604397) PREDICTED: guanine nucleot  (301 aa)
 initn: 1124 init1: 990 opt: 990  Z-score: 1219.0  bits: 233.9 E(85289): 3.7e-61
Smith-Waterman score: 1091; 52.7% identity (77.6% similar) in 313 aa overlap (62-374:1-301)

              40        50        60        70        80        90 
pF1KB6 LLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMR
                                     ::::::.:::.:.::::  :::::::..:.
XP_016                               MRIIHGSGYSDEDRKGFTKLVYQNIFTAMQ
                                             10        20        30

             100       110       120       130       140       150 
pF1KB6 AMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERR
       :::.::. :.: .   ..:..:...   .  ::. . .. . :.. ::.: ::. ::.::
XP_016 AMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSMLSREQVEAIKQLWQDPGIQECYDRR
               40        50        60        70        80        90

             160       170       180       190       200       210 
pF1KB6 REFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGG
       ::..: ::: :::. ..::.  ..::: ::::: :.::::: :: :....  .:.:::::
XP_016 REYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGG
              100       110       120       130       140       150

             220       230       240       250       260       270 
pF1KB6 QKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTS
       :.:::.:::::::.: ..:.:..:::::: : : ..::::.:: ::: ::.  ::: ..:
XP_016 QRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSS
              160       170       180       190       200       210

             280       290       300       310       320       330 
pF1KB6 VILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSK
       ::::::: :.:::::  ::: .::: . :::::..::. ::: .:        ..:.   
XP_016 VILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRAARDFILKLYQD------QNPD---
              220       230       240       250             260    

             340       350       360       370    
pF1KB6 KGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
          . . ..::.::::::.::: ::  :.:..:   : :.::.
XP_016 ---KEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNLV
                270       280       290       300 

>>NP_002060 (OMIM: 139310) guanine nucleotide-binding pr  (354 aa)
 initn: 954 init1: 629 opt: 883  Z-score: 1086.5  bits: 209.6 E(85289): 8.8e-54
Smith-Waterman score: 962; 43.7% identity (69.8% similar) in 364 aa overlap (13-374:3-354)

               10         20        30        40        50         
pF1KB6 MARSLTWRCCPWC-LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFI
                   : :. ..:::.. .. :.: : :. ..   :.:::::: :::::::..
NP_002           MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIV
                         10        20        30        40        50

      60        70        80        90       100       110         
pF1KB6 KQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHA-SLVMS
       :::.::: ::::::: : .. .::.: . :. :.:.:: ::.: :.       : .: . 
NP_002 KQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVL
               60        70        80        90       100       110

      120       130       140       150       160       170        
pF1KB6 QDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPT
           .   .  . :.... ::.:.:..::..: ::..: :::.:::. :.::.. .:.::
NP_002 AGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPT
              120       130       140       150       160       170

      180       190       200       210       220       230        
pF1KB6 AQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEY
        :::::.:. :::: :  :. .  .... :::::.:::::::::::.: :.:. ..::.:
NP_002 QQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDY
              180       190       200       210       220       230

      240       250       260       270       280       290        
pF1KB6 DQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSF
       :  : :... :::.::. :: .: .  :: .::.:::::: :..::::  : :.  .: .
NP_002 DLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEY
              240       250       260       270       280       290

      300       310       320       330       340       350        
pF1KB6 QGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKD
        : .   :::           :  :    :  .:   ......:.::::::.:.. ::  
NP_002 AGSNTYEEAAA----------YIQC--QFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDA
              300                   310       320       330        

      360       370    
pF1KB6 VRDSVLARYLDEINLL
       : : ..   : . .:.
NP_002 VTDVIIKNNLKDCGLF
      340       350    

>>NP_002061 (OMIM: 139360,192605) guanine nucleotide-bin  (355 aa)
 initn: 946 init1: 618 opt: 877  Z-score: 1079.2  bits: 208.3 E(85289): 2.3e-53
Smith-Waterman score: 954; 43.0% identity (69.3% similar) in 365 aa overlap (13-374:3-355)

               10         20        30        40        50         
pF1KB6 MARSLTWRCCPWC-LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFI
                   : .. ..::::. .. :.. : :. ..   :.:::::: :::::::..
NP_002           MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIV
                         10        20        30        40        50

      60        70        80        90       100       110         
pF1KB6 KQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHAS--LVM
       :::.:::  :::::: . .: .::.: . :. :...::  ::: :. :     :   ...
NP_002 KQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFAL
               60        70        80        90       100       110

       120       130       140       150       160       170       
pF1KB6 SQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVP
       :    .  ..    ..... :: : :..::. : ::..: :::.:::. ::::..  :.:
NP_002 SCTAEEQGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIP
              120       130       140       150       160       170

       180       190       200       210       220       230       
pF1KB6 TAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSE
       : :::::.:. :::: :  :. .  .... :::::.:::::::::::.: :.:. ..:: 
NP_002 TQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSA
              180       190       200       210       220       230

       240       250       260       270       280       290       
pF1KB6 YDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPS
       ::  : :... :::.::. :: .: .  :: .::.:::::: :..::::  : :.  :: 
NP_002 YDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPE
              240       250       260       270       280       290

       300       310       320       330       340       350       
pF1KB6 FQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFK
       . : ..  :::. .: . .           :  .:   ......:.::::::.:.. :: 
NP_002 YTGANKYDEAAS-YIQSKF-----------EDLNKRKDTKEIYTHFTCATDTKNVQFVFD
              300                   310       320       330        

       360       370    
pF1KB6 DVRDSVLARYLDEINLL
        : : ..   : . .:.
NP_002 AVTDVIIKNNLKDCGLF
      340       350     

>>NP_006487 (OMIM: 139370,602483) guanine nucleotide-bin  (354 aa)
 initn: 943 init1: 627 opt: 874  Z-score: 1075.5  bits: 207.6 E(85289): 3.6e-53
Smith-Waterman score: 953; 43.8% identity (69.3% similar) in 365 aa overlap (13-373:3-353)

               10         20        30        40        50         
pF1KB6 MARSLTWRCCPWC-LTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFI
                   : :. ..:::.. .. :.: : :. ..   :.:::::: :::::::..
NP_006           MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIV
                         10        20        30        40        50

      60        70        80        90       100          110      
pF1KB6 KQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPF---SRPESKHHASLV
       :::.:::  ::::.: : .. .::.: . :. :.:.:: ::.: :   .: .. ..  ..
NP_006 KQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVL
               60        70        80        90       100       110

        120       130       140       150       160       170      
pF1KB6 MSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYV
        ..    : : :   :.... ::::.:..::. : ::..: ::: :::. :.::.. .:.
NP_006 AGSAEEGVMTPE--LAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYI
              120         130       140       150       160        

        180       190       200       210       220       230      
pF1KB6 PTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLS
       :: :::::.:. :::: :  :. .   ... :::::.:::::::::::.: :.:. ..::
NP_006 PTQQDVLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALS
      170       180       190       200       210       220        

        240       250       260       270       280       290      
pF1KB6 EYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFP
       .::  : :... :::.::. :: .: .  ::  ::.:::::: :..::::  : :.  .:
NP_006 DYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYP
      230       240       250       260       270       280        

        300       310       320       330       340       350      
pF1KB6 SFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVF
        . : .   :::           :  :    :  ..   ......:.::::::.:.. ::
NP_006 EYTGSNTYEEAAA----------YIQC--QFEDLNRRKDTKEIYTHFTCATDTKNVQFVF
      290       300                   310       320       330      

        360       370    
pF1KB6 KDVRDSVLARYLDEINLL
         : : ..   : : .: 
NP_006 DAVTDVIIKNNLKECGLY
        340       350    

>>NP_001095856 (OMIM: 139395) guanine nucleotide-binding  (354 aa)
 initn: 932 init1: 632 opt: 873  Z-score: 1074.3  bits: 207.4 E(85289): 4.3e-53
Smith-Waterman score: 953; 43.1% identity (70.2% similar) in 362 aa overlap (14-374:5-354)

               10        20        30        40        50        60
pF1KB6 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK
                    .. . : .:. ..:... : :. ..:   .:::::: :::::::..:
NP_001          MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVK
                        10        20        30        40        50 

               70        80        90       100        110         
pF1KB6 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPES-KHHASLVMSQ
       ::.:::  ::::.:   :. ..:.: . :. :...::  : : .  :.: . . .:    
NP_001 QMKIIHKNGYSEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMA
              60        70        80        90       100       110 

     120       130       140       150       160       170         
pF1KB6 DPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTA
       .  .   .  . : ... :::: ::.::.::  :..: :::.:::. :.:::  ::::. 
NP_001 NTLEDGGMTPQLAEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNE
             120       130       140       150       160       170 

     180       190       200       210       220       230         
pF1KB6 QDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYD
       ::::.::. :::: :  :: .  ..:. :::::.:::::::::::.:  .:. :.:: ::
NP_001 QDVLHSRVKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYD
             180       190       200       210       220       230 

     240       250       260       270       280       290         
pF1KB6 QCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQ
       . : :... :::.::: ::..: .  .:..::..::::: ::..::.   ::.  :: . 
NP_001 MVLVEDEEVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYT
             240       250       260       270       280       290 

     300       310       320       330       340       350         
pF1KB6 GPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDV
       ::.   : :  .: ...  .         . ::  ......::.::::::::.. ::  :
NP_001 GPNT-FEDAGNYIKNQFLDL---------NLKK--EDKEIYSHMTCATDTQNVKFVFDAV
              300       310                  320       330         

     360       370    
pF1KB6 RDSVLARYLDEINLL
        : .. . : . .:.
NP_001 TDIIIKENLKDCGLF
     340       350    




374 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 23:20:00 2016 done: Fri Nov  4 23:20:01 2016
 Total Scan time:  6.640 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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