Result of FASTA (omim) for
pF1KF0414
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KF0414, 1058 aa
1>>>pF1KF0414 1058 - 1058 aa - 1058 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0486+/-0.00043; mu= 2.0420+/- 0.027
mean_var=350.4868+/-72.836, 0's: 0 Z-trim(121.0): 177 B-trim: 132 in 1/56
Lambda= 0.068508
statistics sampled from 36727 (36920) to 36727 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.433), width: 16
Scan time: 17.450
The best scores are: opt bits E(85289)
XP_011540757 (OMIM: 612836) PREDICTED: 1-phosphati (1580) 6782 685.5 6.3e-196
XP_011540758 (OMIM: 612836) PREDICTED: 1-phosphati (1580) 6782 685.5 6.3e-196
XP_016858360 (OMIM: 612836) PREDICTED: 1-phosphati (1670) 6782 685.5 6.5e-196
XP_016858359 (OMIM: 612836) PREDICTED: 1-phosphati (1678) 6782 685.5 6.5e-196
NP_001289941 (OMIM: 612836) 1-phosphatidylinositol (1129) 6774 684.6 8.6e-196
NP_055453 (OMIM: 612836) 1-phosphatidylinositol 4, (1416) 5643 572.9 4.5e-162
XP_016858361 (OMIM: 612836) PREDICTED: 1-phosphati (1511) 5643 572.9 4.7e-162
NP_001289942 (OMIM: 612836) 1-phosphatidylinositol (1019) 5612 569.7 3e-161
XP_016858363 (OMIM: 612836) PREDICTED: 1-phosphati (1094) 5612 569.7 3.2e-161
XP_016858362 (OMIM: 612836) PREDICTED: 1-phosphati (1475) 3753 386.1 7.9e-106
NP_055811 (OMIM: 612835) 1-phosphatidylinositol 4, (1655) 3564 367.5 3.6e-100
XP_005247296 (OMIM: 612835) PREDICTED: 1-phosphati (1673) 3564 367.5 3.6e-100
XP_016861413 (OMIM: 612835) PREDICTED: 1-phosphati (1684) 3564 367.5 3.6e-100
XP_011510866 (OMIM: 612835) PREDICTED: 1-phosphati (1685) 3564 367.5 3.6e-100
XP_016861418 (OMIM: 612835) PREDICTED: 1-phosphati (1002) 3405 351.5 1.4e-95
NP_001124433 (OMIM: 612835) 1-phosphatidylinositol (1002) 3405 351.5 1.4e-95
XP_016861417 (OMIM: 612835) PREDICTED: 1-phosphati (1014) 3405 351.5 1.4e-95
XP_011510869 (OMIM: 612835) PREDICTED: 1-phosphati (1014) 3405 351.5 1.4e-95
XP_016861416 (OMIM: 612835) PREDICTED: 1-phosphati (1021) 3405 351.5 1.4e-95
XP_011510868 (OMIM: 612835) PREDICTED: 1-phosphati (1675) 3405 351.8 1.9e-95
XP_016861415 (OMIM: 612835) PREDICTED: 1-phosphati (1675) 3405 351.8 1.9e-95
XP_011510867 (OMIM: 612835) PREDICTED: 1-phosphati (1675) 3405 351.8 1.9e-95
NP_001124432 (OMIM: 612835) 1-phosphatidylinositol (1693) 3405 351.8 2e-95
XP_016861412 (OMIM: 612835) PREDICTED: 1-phosphati (1704) 3405 351.8 2e-95
XP_011510864 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 3405 351.8 2e-95
XP_011510863 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 3405 351.8 2e-95
XP_005247295 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 3405 351.8 2e-95
XP_011510862 (OMIM: 612835) PREDICTED: 1-phosphati (1705) 3405 351.8 2e-95
XP_016861414 (OMIM: 612835) PREDICTED: 1-phosphati (1681) 1973 210.2 7.9e-53
XP_016860607 (OMIM: 605939) PREDICTED: 1-phosphati ( 716) 1020 115.7 9.9e-25
XP_016860605 (OMIM: 605939) PREDICTED: 1-phosphati ( 794) 1020 115.7 1.1e-24
XP_011510314 (OMIM: 605939) PREDICTED: 1-phosphati ( 820) 1020 115.7 1.1e-24
XP_016860604 (OMIM: 605939) PREDICTED: 1-phosphati ( 820) 1020 115.7 1.1e-24
XP_016860603 (OMIM: 605939) PREDICTED: 1-phosphati ( 820) 1020 115.7 1.1e-24
NP_116115 (OMIM: 605939) 1-phosphatidylinositol 4, ( 762) 1019 115.6 1.1e-24
XP_005246970 (OMIM: 605939) PREDICTED: 1-phosphati ( 788) 1019 115.6 1.1e-24
XP_016861514 (OMIM: 614276) PREDICTED: inactive ph (1001) 995 113.3 6.9e-24
NP_055999 (OMIM: 614276) inactive phospholipase C- (1001) 995 113.3 6.9e-24
XP_006713136 (OMIM: 614276) PREDICTED: inactive ph (1022) 995 113.3 7e-24
XP_016861513 (OMIM: 614276) PREDICTED: inactive ph (1127) 995 113.4 7.5e-24
NP_001137854 (OMIM: 614276) inactive phospholipase (1127) 995 113.4 7.5e-24
XP_016861512 (OMIM: 614276) PREDICTED: inactive ph (1127) 995 113.4 7.5e-24
XP_016861511 (OMIM: 614276) PREDICTED: inactive ph (1127) 995 113.4 7.5e-24
XP_016859829 (OMIM: 600597) PREDICTED: inactive ph ( 997) 914 105.3 1.8e-21
XP_016859828 (OMIM: 600597) PREDICTED: inactive ph (1016) 914 105.3 1.8e-21
XP_005246701 (OMIM: 600597) PREDICTED: inactive ph (1016) 914 105.3 1.8e-21
XP_011509653 (OMIM: 600597) PREDICTED: inactive ph (1016) 914 105.3 1.8e-21
XP_005246700 (OMIM: 600597) PREDICTED: inactive ph (1021) 914 105.3 1.8e-21
NP_006217 (OMIM: 600597) inactive phospholipase C- (1095) 914 105.4 1.9e-21
NP_588614 (OMIM: 608795) 1-phosphatidylinositol 4, ( 789) 902 104.0 3.4e-21
>>XP_011540757 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1580 aa)
initn: 6810 init1: 6774 opt: 6782 Z-score: 3638.5 bits: 685.5 E(85289): 6.3e-196
Smith-Waterman score: 6799; 97.5% identity (97.9% similar) in 1036 aa overlap (1-1024:151-1185)
10 20 30
pF1KF0 MAGISDEDSLARRQRTRDQWLKQTFDEADK
::::::::::::::::::::::::::::::
XP_011 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
130 140 150 160 170 180
40 50 60 70 80 90
pF1KF0 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
190 200 210 220 230 240
100 110 120 130 140 150
pF1KF0 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
250 260 270 280 290 300
160 170 180 190 200 210
pF1KF0 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
310 320 330 340 350 360
220 230 240 250 260 270
pF1KF0 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
370 380 390 400 410 420
280 290 300 310 320 330
pF1KF0 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
430 440 450 460 470 480
340 350 360 370 380 390
pF1KF0 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
490 500 510 520 530 540
400 410 420 430 440 450
pF1KF0 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
550 560 570 580 590 600
460 470 480 490 500 510
pF1KF0 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
610 620 630 640 650 660
520 530 540 550 560 570
pF1KF0 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
670 680 690 700 710 720
580 590 600 610 620 630
pF1KF0 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
730 740 750 760 770 780
640 650 660 670 680 690
pF1KF0 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
790 800 810 820 830 840
700 710 720 730 740 750
pF1KF0 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQVLGLKGLFLRGPK
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_011 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPK
850 860 870 880 890 900
760 770 780 790 800 810
pF1KF0 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
910 920 930 940 950 960
820 830 840 850 860 870
pF1KF0 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATCMKCV
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_011 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPPRVLDGPGPAGMAATCMKCV
970 980 990 1000 1010 1020
880 890 900 910 920 930
pF1KF0 VGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSREAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSREAP
1030 1040 1050 1060 1070 1080
940 950 960 970 980 990
pF1KF0 KGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQKLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQKLEE
1090 1100 1110 1120 1130 1140
1000 1010 1020 1030
pF1KF0 IRSKSPMFSAG-------KPLLP-C----VVLPHAPGMAGPGSPAAASAWTVSPRVLVLV
:::::::::: .:: : : .. ::: :: :::
XP_011 IRSKSPMFSADTRPLSTQRPLPPLCSLETIAEEPAPG-PGPPPPAAVPTSSSQGRPPYPT
1150 1160 1170 1180 1190
1040 1050
pF1KF0 ALYPWHCLRGTLLPWLACGP
XP_011 GPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQTDGRSQPRTLGHLPVIRRVK
1200 1210 1220 1230 1240 1250
>>XP_011540758 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1580 aa)
initn: 6810 init1: 6774 opt: 6782 Z-score: 3638.5 bits: 685.5 E(85289): 6.3e-196
Smith-Waterman score: 6799; 97.5% identity (97.9% similar) in 1036 aa overlap (1-1024:151-1185)
10 20 30
pF1KF0 MAGISDEDSLARRQRTRDQWLKQTFDEADK
::::::::::::::::::::::::::::::
XP_011 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
130 140 150 160 170 180
40 50 60 70 80 90
pF1KF0 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
190 200 210 220 230 240
100 110 120 130 140 150
pF1KF0 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
250 260 270 280 290 300
160 170 180 190 200 210
pF1KF0 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
310 320 330 340 350 360
220 230 240 250 260 270
pF1KF0 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
370 380 390 400 410 420
280 290 300 310 320 330
pF1KF0 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
430 440 450 460 470 480
340 350 360 370 380 390
pF1KF0 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
490 500 510 520 530 540
400 410 420 430 440 450
pF1KF0 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
550 560 570 580 590 600
460 470 480 490 500 510
pF1KF0 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
610 620 630 640 650 660
520 530 540 550 560 570
pF1KF0 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
670 680 690 700 710 720
580 590 600 610 620 630
pF1KF0 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
730 740 750 760 770 780
640 650 660 670 680 690
pF1KF0 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
790 800 810 820 830 840
700 710 720 730 740 750
pF1KF0 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQVLGLKGLFLRGPK
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_011 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPK
850 860 870 880 890 900
760 770 780 790 800 810
pF1KF0 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
910 920 930 940 950 960
820 830 840 850 860 870
pF1KF0 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATCMKCV
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_011 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPPRVLDGPGPAGMAATCMKCV
970 980 990 1000 1010 1020
880 890 900 910 920 930
pF1KF0 VGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSREAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSREAP
1030 1040 1050 1060 1070 1080
940 950 960 970 980 990
pF1KF0 KGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQKLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQKLEE
1090 1100 1110 1120 1130 1140
1000 1010 1020 1030
pF1KF0 IRSKSPMFSAG-------KPLLP-C----VVLPHAPGMAGPGSPAAASAWTVSPRVLVLV
:::::::::: .:: : : .. ::: :: :::
XP_011 IRSKSPMFSADTRPLSTQRPLPPLCSLETIAEEPAPG-PGPPPPAAVPTSSSQGRPPYPT
1150 1160 1170 1180 1190
1040 1050
pF1KF0 ALYPWHCLRGTLLPWLACGP
XP_011 GPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQTDGRSQPRTLGHLPVIRRVK
1200 1210 1220 1230 1240 1250
>>XP_016858360 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1670 aa)
initn: 6810 init1: 6774 opt: 6782 Z-score: 3638.2 bits: 685.5 E(85289): 6.5e-196
Smith-Waterman score: 6799; 97.5% identity (97.9% similar) in 1036 aa overlap (1-1024:241-1275)
10 20 30
pF1KF0 MAGISDEDSLARRQRTRDQWLKQTFDEADK
::::::::::::::::::::::::::::::
XP_016 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
220 230 240 250 260 270
40 50 60 70 80 90
pF1KF0 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
280 290 300 310 320 330
100 110 120 130 140 150
pF1KF0 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
340 350 360 370 380 390
160 170 180 190 200 210
pF1KF0 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
400 410 420 430 440 450
220 230 240 250 260 270
pF1KF0 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
460 470 480 490 500 510
280 290 300 310 320 330
pF1KF0 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
520 530 540 550 560 570
340 350 360 370 380 390
pF1KF0 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
580 590 600 610 620 630
400 410 420 430 440 450
pF1KF0 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
640 650 660 670 680 690
460 470 480 490 500 510
pF1KF0 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
700 710 720 730 740 750
520 530 540 550 560 570
pF1KF0 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
760 770 780 790 800 810
580 590 600 610 620 630
pF1KF0 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
820 830 840 850 860 870
640 650 660 670 680 690
pF1KF0 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
880 890 900 910 920 930
700 710 720 730 740 750
pF1KF0 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQVLGLKGLFLRGPK
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_016 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPK
940 950 960 970 980 990
760 770 780 790 800 810
pF1KF0 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
1000 1010 1020 1030 1040 1050
820 830 840 850 860 870
pF1KF0 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATCMKCV
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_016 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPPRVLDGPGPAGMAATCMKCV
1060 1070 1080 1090 1100 1110
880 890 900 910 920 930
pF1KF0 VGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSREAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSREAP
1120 1130 1140 1150 1160 1170
940 950 960 970 980 990
pF1KF0 KGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQKLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQKLEE
1180 1190 1200 1210 1220 1230
1000 1010 1020 1030
pF1KF0 IRSKSPMFSAG-------KPLLP-C----VVLPHAPGMAGPGSPAAASAWTVSPRVLVLV
:::::::::: .:: : : .. ::: :: :::
XP_016 IRSKSPMFSADTRPLSTQRPLPPLCSLETIAEEPAPG-PGPPPPAAVPTSSSQGRPPYPT
1240 1250 1260 1270 1280
1040 1050
pF1KF0 ALYPWHCLRGTLLPWLACGP
XP_016 GPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQTDGRSQPRTLGHLPVIRRVK
1290 1300 1310 1320 1330 1340
>>XP_016858359 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1678 aa)
initn: 6810 init1: 6774 opt: 6782 Z-score: 3638.2 bits: 685.5 E(85289): 6.5e-196
Smith-Waterman score: 6799; 97.5% identity (97.9% similar) in 1036 aa overlap (1-1024:249-1283)
10 20 30
pF1KF0 MAGISDEDSLARRQRTRDQWLKQTFDEADK
::::::::::::::::::::::::::::::
XP_016 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
220 230 240 250 260 270
40 50 60 70 80 90
pF1KF0 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
280 290 300 310 320 330
100 110 120 130 140 150
pF1KF0 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
340 350 360 370 380 390
160 170 180 190 200 210
pF1KF0 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
400 410 420 430 440 450
220 230 240 250 260 270
pF1KF0 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
460 470 480 490 500 510
280 290 300 310 320 330
pF1KF0 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
520 530 540 550 560 570
340 350 360 370 380 390
pF1KF0 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
580 590 600 610 620 630
400 410 420 430 440 450
pF1KF0 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
640 650 660 670 680 690
460 470 480 490 500 510
pF1KF0 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
700 710 720 730 740 750
520 530 540 550 560 570
pF1KF0 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
760 770 780 790 800 810
580 590 600 610 620 630
pF1KF0 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
820 830 840 850 860 870
640 650 660 670 680 690
pF1KF0 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
880 890 900 910 920 930
700 710 720 730 740 750
pF1KF0 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQVLGLKGLFLRGPK
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_016 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPK
940 950 960 970 980 990
760 770 780 790 800 810
pF1KF0 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
1000 1010 1020 1030 1040 1050
820 830 840 850 860 870
pF1KF0 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATCMKCV
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_016 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPPRVLDGPGPAGMAATCMKCV
1060 1070 1080 1090 1100 1110
880 890 900 910 920 930
pF1KF0 VGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSREAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSREAP
1120 1130 1140 1150 1160 1170
940 950 960 970 980 990
pF1KF0 KGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQKLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQKLEE
1180 1190 1200 1210 1220 1230
1000 1010 1020 1030
pF1KF0 IRSKSPMFSAG-------KPLLP-C----VVLPHAPGMAGPGSPAAASAWTVSPRVLVLV
:::::::::: .:: : : .. ::: :: :::
XP_016 IRSKSPMFSADTRPLSTQRPLPPLCSLETIAEEPAPG-PGPPPPAAVPTSSSQGRPPYPT
1240 1250 1260 1270 1280 1290
1040 1050
pF1KF0 ALYPWHCLRGTLLPWLACGP
XP_016 GPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQTDGRSQPRTLGHLPVIRRVK
1300 1310 1320 1330 1340 1350
>>NP_001289941 (OMIM: 612836) 1-phosphatidylinositol 4,5 (1129 aa)
initn: 6774 init1: 6774 opt: 6774 Z-score: 3636.0 bits: 684.6 E(85289): 8.6e-196
Smith-Waterman score: 6774; 99.8% identity (99.9% similar) in 1000 aa overlap (1-1000:127-1126)
10 20 30
pF1KF0 MAGISDEDSLARRQRTRDQWLKQTFDEADK
::::::::::::::::::::::::::::::
NP_001 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
100 110 120 130 140 150
40 50 60 70 80 90
pF1KF0 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
160 170 180 190 200 210
100 110 120 130 140 150
pF1KF0 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
220 230 240 250 260 270
160 170 180 190 200 210
pF1KF0 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
280 290 300 310 320 330
220 230 240 250 260 270
pF1KF0 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
340 350 360 370 380 390
280 290 300 310 320 330
pF1KF0 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
400 410 420 430 440 450
340 350 360 370 380 390
pF1KF0 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
460 470 480 490 500 510
400 410 420 430 440 450
pF1KF0 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
520 530 540 550 560 570
460 470 480 490 500 510
pF1KF0 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
580 590 600 610 620 630
520 530 540 550 560 570
pF1KF0 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
640 650 660 670 680 690
580 590 600 610 620 630
pF1KF0 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
700 710 720 730 740 750
640 650 660 670 680 690
pF1KF0 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
760 770 780 790 800 810
700 710 720 730 740 750
pF1KF0 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQVLGLKGLFLRGPK
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPK
820 830 840 850 860 870
760 770 780 790 800 810
pF1KF0 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
880 890 900 910 920 930
820 830 840 850 860 870
pF1KF0 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATCMKCV
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPPRVLDGPGPAGMAATCMKCV
940 950 960 970 980 990
880 890 900 910 920 930
pF1KF0 VGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSREAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGSCAGVNTGGLQRERPPSPGPASRQAAIRQQPRARADSLGAPCCGLDPHAIPGRSREAP
1000 1010 1020 1030 1040 1050
940 950 960 970 980 990
pF1KF0 KGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQKLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGPGAWRQGPGGSGSMSSDSSSPDSPGIPERSPRWPEGACRQPGALQGEMSALFAQKLEE
1060 1070 1080 1090 1100 1110
1000 1010 1020 1030 1040 1050
pF1KF0 IRSKSPMFSAGKPLLPCVVLPHAPGMAGPGSPAAASAWTVSPRVLVLVALYPWHCLRGTL
::::::::::
NP_001 IRSKSPMFSAVRN
1120
>>NP_055453 (OMIM: 612836) 1-phosphatidylinositol 4,5-bi (1416 aa)
initn: 5653 init1: 5614 opt: 5643 Z-score: 3030.7 bits: 572.9 E(85289): 4.5e-162
Smith-Waterman score: 5672; 81.7% identity (85.8% similar) in 1103 aa overlap (1-1046:154-1240)
10 20 30
pF1KF0 MAGISDEDSLARRQRTRDQWLKQTFDEADK
::::::::::::::::::::::::::::::
NP_055 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
130 140 150 160 170 180
40 50 60 70 80 90
pF1KF0 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
190 200 210 220 230 240
100 110 120 130 140 150
pF1KF0 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
250 260 270 280 290 300
160 170 180 190 200 210
pF1KF0 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
310 320 330 340 350 360
220 230 240 250 260 270
pF1KF0 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
370 380 390 400 410 420
280 290 300 310 320 330
pF1KF0 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
430 440 450 460 470 480
340 350 360 370 380 390
pF1KF0 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
490 500 510 520 530 540
400 410 420 430 440 450
pF1KF0 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
550 560 570 580 590 600
460 470 480 490 500 510
pF1KF0 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
610 620 630 640 650 660
520 530 540 550 560 570
pF1KF0 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
670 680 690 700 710 720
580 590 600 610 620 630
pF1KF0 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
730 740 750 760 770 780
640 650 660 670 680 690
pF1KF0 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
790 800 810 820 830 840
700 710 720 730 740 750
pF1KF0 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQVLGLKGLFLRGPK
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_055 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPK
850 860 870 880 890 900
760 770 780 790 800 810
pF1KF0 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
910 920 930 940 950 960
820 830 840 850 860
pF1KF0 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLD--------GPGPAGM
::::::::::::::::::::::: : .. . : :: :. ::::
NP_055 VPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLP----PLCSLETIAEEPAPGPGPPPP
970 980 990 1000 1010
870 880 890
pF1KF0 AATCMKCV-------VGSCAGVNTGGLQRERP----PSP------------GPASRQAAI
::. . .: :.: . . :.: : : .:.: :.
NP_055 AAVPTSSSQGRPPYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGS-QTDG
1020 1030 1040 1050 1060 1070
900 910 920 930 940
pF1KF0 RQQPRA--------RADSLGA----PCCGLDPHAIP----GRSREAPKGPGAW-RQGP-G
:.:::. :. : : : : : : : . .: . : : : :
NP_055 RSQPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDPLWQRLEPCG
1080 1090 1100 1110 1120 1130
950 960 970 980 990
pF1KF0 GSGSMSSDSSSPDSPGIPERS-PRWPEGACRQ--PGALQGEMSALFAQKLEEIRSKSPMF
:.::.:: .: . . : : : :. :: .:.. : .:
NP_055 HRDSVSSSSSMSSSDTVIDLSLPSLGLGRSRENLAGAHMGRLPP---------RPHSA--
1140 1150 1160 1170 1180
1000 1010 1020 1030 1040 1050
pF1KF0 SAGKPLLPCVVLPHA-PGMAGPGS----PAAASAWTVSPRVLVLVALYPWHCLRGTLLPW
::..: :: :. .. :.. . :. : . ...::. : :: ::
NP_055 SAARPDLPPVTKSKSNPNLRATGQRPPIPDELQPRSLAPRMAGLPFRPPWGCLSLVGVQD
1190 1200 1210 1220 1230 1240
pF1KF0 LACGP
NP_055 CPVAAKSKSLGDLTADDFAPSFEGGSRRLSHSLGLPGGTRRVSGPGVRRDTLTEQLRWLT
1250 1260 1270 1280 1290 1300
>>XP_016858361 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1511 aa)
initn: 5653 init1: 5614 opt: 5643 Z-score: 3030.4 bits: 572.9 E(85289): 4.7e-162
Smith-Waterman score: 5672; 81.7% identity (85.8% similar) in 1103 aa overlap (1-1046:249-1335)
10 20 30
pF1KF0 MAGISDEDSLARRQRTRDQWLKQTFDEADK
::::::::::::::::::::::::::::::
XP_016 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
220 230 240 250 260 270
40 50 60 70 80 90
pF1KF0 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
280 290 300 310 320 330
100 110 120 130 140 150
pF1KF0 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
340 350 360 370 380 390
160 170 180 190 200 210
pF1KF0 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
400 410 420 430 440 450
220 230 240 250 260 270
pF1KF0 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
460 470 480 490 500 510
280 290 300 310 320 330
pF1KF0 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
520 530 540 550 560 570
340 350 360 370 380 390
pF1KF0 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
580 590 600 610 620 630
400 410 420 430 440 450
pF1KF0 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
640 650 660 670 680 690
460 470 480 490 500 510
pF1KF0 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
700 710 720 730 740 750
520 530 540 550 560 570
pF1KF0 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
760 770 780 790 800 810
580 590 600 610 620 630
pF1KF0 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
820 830 840 850 860 870
640 650 660 670 680 690
pF1KF0 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
880 890 900 910 920 930
700 710 720 730 740 750
pF1KF0 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQVLGLKGLFLRGPK
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_016 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPK
940 950 960 970 980 990
760 770 780 790 800 810
pF1KF0 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
1000 1010 1020 1030 1040 1050
820 830 840 850 860
pF1KF0 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLD--------GPGPAGM
::::::::::::::::::::::: : .. . : :: :. ::::
XP_016 VPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLP----PLCSLETIAEEPAPGPGPPPP
1060 1070 1080 1090 1100 1110
870 880 890
pF1KF0 AATCMKCV-------VGSCAGVNTGGLQRERP----PSP------------GPASRQAAI
::. . .: :.: . . :.: : : .:.: :.
XP_016 AAVPTSSSQGRPPYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGS-QTDG
1120 1130 1140 1150 1160 1170
900 910 920 930 940
pF1KF0 RQQPRA--------RADSLGA----PCCGLDPHAIP----GRSREAPKGPGAW-RQGP-G
:.:::. :. : : : : : : : . .: . : : : :
XP_016 RSQPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDPLWQRLEPCG
1180 1190 1200 1210 1220 1230
950 960 970 980 990
pF1KF0 GSGSMSSDSSSPDSPGIPERS-PRWPEGACRQ--PGALQGEMSALFAQKLEEIRSKSPMF
:.::.:: .: . . : : : :. :: .:.. : .:
XP_016 HRDSVSSSSSMSSSDTVIDLSLPSLGLGRSRENLAGAHMGRLPP---------RPHSA--
1240 1250 1260 1270 1280
1000 1010 1020 1030 1040 1050
pF1KF0 SAGKPLLPCVVLPHA-PGMAGPGS----PAAASAWTVSPRVLVLVALYPWHCLRGTLLPW
::..: :: :. .. :.. . :. : . ...::. : :: ::
XP_016 SAARPDLPPVTKSKSNPNLRATGQRPPIPDELQPRSLAPRMAGLPFRPPWGCLSLVGVQD
1290 1300 1310 1320 1330 1340
pF1KF0 LACGP
XP_016 CPVAAKSKSLGDLTADDFAPSFEGGSRRLSHSLGLPGGTRRVSGPGVRRDTLTEQLRWLT
1350 1360 1370 1380 1390 1400
>>NP_001289942 (OMIM: 612836) 1-phosphatidylinositol 4,5 (1019 aa)
initn: 5676 init1: 5612 opt: 5612 Z-score: 3015.9 bits: 569.7 E(85289): 3e-161
Smith-Waterman score: 5612; 99.3% identity (99.8% similar) in 840 aa overlap (1-840:174-1013)
10 20 30
pF1KF0 MAGISDEDSLARRQRTRDQWLKQTFDEADK
::::::::::::::::::::::::::::::
NP_001 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
150 160 170 180 190 200
40 50 60 70 80 90
pF1KF0 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
210 220 230 240 250 260
100 110 120 130 140 150
pF1KF0 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
270 280 290 300 310 320
160 170 180 190 200 210
pF1KF0 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
330 340 350 360 370 380
220 230 240 250 260 270
pF1KF0 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
390 400 410 420 430 440
280 290 300 310 320 330
pF1KF0 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
450 460 470 480 490 500
340 350 360 370 380 390
pF1KF0 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
510 520 530 540 550 560
400 410 420 430 440 450
pF1KF0 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
570 580 590 600 610 620
460 470 480 490 500 510
pF1KF0 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
630 640 650 660 670 680
520 530 540 550 560 570
pF1KF0 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
690 700 710 720 730 740
580 590 600 610 620 630
pF1KF0 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
750 760 770 780 790 800
640 650 660 670 680 690
pF1KF0 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
810 820 830 840 850 860
700 710 720 730 740 750
pF1KF0 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQVLGLKGLFLRGPK
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPK
870 880 890 900 910 920
760 770 780 790 800 810
pF1KF0 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
930 940 950 960 970 980
820 830 840 850 860 870
pF1KF0 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATCMKCV
:::::::::::::::::::::::. .: .:
NP_001 VPPGPGPAPEAPAQEGPGSGSPRAATPPTVQPGNHR
990 1000 1010
>>XP_016858363 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1094 aa)
initn: 5612 init1: 5612 opt: 5612 Z-score: 3015.5 bits: 569.7 E(85289): 3.2e-161
Smith-Waterman score: 5612; 99.3% identity (99.8% similar) in 840 aa overlap (1-840:249-1088)
10 20 30
pF1KF0 MAGISDEDSLARRQRTRDQWLKQTFDEADK
::::::::::::::::::::::::::::::
XP_016 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
220 230 240 250 260 270
40 50 60 70 80 90
pF1KF0 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
280 290 300 310 320 330
100 110 120 130 140 150
pF1KF0 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
340 350 360 370 380 390
160 170 180 190 200 210
pF1KF0 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
400 410 420 430 440 450
220 230 240 250 260 270
pF1KF0 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
460 470 480 490 500 510
280 290 300 310 320 330
pF1KF0 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
520 530 540 550 560 570
340 350 360 370 380 390
pF1KF0 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
580 590 600 610 620 630
400 410 420 430 440 450
pF1KF0 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
640 650 660 670 680 690
460 470 480 490 500 510
pF1KF0 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
700 710 720 730 740 750
520 530 540 550 560 570
pF1KF0 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
760 770 780 790 800 810
580 590 600 610 620 630
pF1KF0 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
820 830 840 850 860 870
640 650 660 670 680 690
pF1KF0 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
880 890 900 910 920 930
700 710 720 730 740 750
pF1KF0 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQVLGLKGLFLRGPK
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_016 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPK
940 950 960 970 980 990
760 770 780 790 800 810
pF1KF0 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
1000 1010 1020 1030 1040 1050
820 830 840 850 860 870
pF1KF0 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLDGPGPAGMAATCMKCV
:::::::::::::::::::::::. .: .:
XP_016 VPPGPGPAPEAPAQEGPGSGSPRAATPPTVQPGNHR
1060 1070 1080 1090
>>XP_016858362 (OMIM: 612836) PREDICTED: 1-phosphatidyli (1475 aa)
initn: 3780 init1: 3683 opt: 3753 Z-score: 2020.9 bits: 386.1 E(85289): 7.9e-106
Smith-Waterman score: 5334; 78.4% identity (82.5% similar) in 1103 aa overlap (1-1046:249-1299)
10 20 30
pF1KF0 MAGISDEDSLARRQRTRDQWLKQTFDEADK
::::::::::::::::::::::::::::::
XP_016 IYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADK
220 230 240 250 260 270
40 50 60 70 80 90
pF1KF0 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRD
280 290 300 310 320 330
100 110 120 130 140 150
pF1KF0 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGID
340 350 360 370 380 390
160 170 180 190 200 210
pF1KF0 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVL
400 410 420 430 440 450
220 230 240 250 260 270
pF1KF0 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHC
460 470 480 490 500 510
280 290 300 310 320 330
pF1KF0 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEE
520 530 540 550 560 570
340 350 360 370 380 390
pF1KF0 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVST
580 590 600 610 620 630
400 410 420 430 440 450
pF1KF0 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQ
640 650 660 670 680 690
460 470 480 490 500 510
pF1KF0 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQIL
700 710 720 730 740 750
520 530 540 550 560 570
pF1KF0 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAK
::::::::::::::::::::::::::::::::::::::::::
XP_016 QQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQM------------------
760 770 780 790 800
580 590 600 610 620 630
pF1KF0 FSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
::::::::::::::::::::::::::::::::::::::::::
XP_016 ------------------GVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGE
810 820 830 840
640 650 660 670 680 690
pF1KF0 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPI
850 860 870 880 890 900
700 710 720 730 740 750
pF1KF0 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQVLGLKGLFLRGPK
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_016 GRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPK
910 920 930 940 950 960
760 770 780 790 800 810
pF1KF0 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDV
970 980 990 1000 1010 1020
820 830 840 850 860
pF1KF0 VPPGPGPAPEAPAQEGPGSGSPRGKAPAAVAEKSPVRVRPLRVLD--------GPGPAGM
::::::::::::::::::::::: : .. . : :: :. ::::
XP_016 VPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLP----PLCSLETIAEEPAPGPGPPPP
1030 1040 1050 1060 1070
870 880 890
pF1KF0 AATCMKCV-------VGSCAGVNTGGLQRERP----PSP------------GPASRQAAI
::. . .: :.: . . :.: : : .:.: :.
XP_016 AAVPTSSSQGRPPYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGS-QTDG
1080 1090 1100 1110 1120 1130
900 910 920 930 940
pF1KF0 RQQPRA--------RADSLGA----PCCGLDPHAIP----GRSREAPKGPGAW-RQGP-G
:.:::. :. : : : : : : : . .: . : : : :
XP_016 RSQPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDPLWQRLEPCG
1140 1150 1160 1170 1180 1190
950 960 970 980 990
pF1KF0 GSGSMSSDSSSPDSPGIPERS-PRWPEGACRQ--PGALQGEMSALFAQKLEEIRSKSPMF
:.::.:: .: . . : : : :. :: .:.. : .:
XP_016 HRDSVSSSSSMSSSDTVIDLSLPSLGLGRSRENLAGAHMGRLPP---------RPHSA--
1200 1210 1220 1230 1240
1000 1010 1020 1030 1040 1050
pF1KF0 SAGKPLLPCVVLPHA-PGMAGPGS----PAAASAWTVSPRVLVLVALYPWHCLRGTLLPW
::..: :: :. .. :.. . :. : . ...::. : :: ::
XP_016 SAARPDLPPVTKSKSNPNLRATGQRPPIPDELQPRSLAPRMAGLPFRPPWGCLSLVGVQD
1250 1260 1270 1280 1290 1300
pF1KF0 LACGP
XP_016 CPVAAKSKSLGDLTADDFAPSFEGGSRRLSHSLGLPGGTRRVSGPGVRRDTLTEQLRWLT
1310 1320 1330 1340 1350 1360
1058 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:37:02 2016 done: Sat Nov 5 06:37:05 2016
Total Scan time: 17.450 Total Display time: 0.510
Function used was FASTA [36.3.4 Apr, 2011]