Result of FASTA (omim) for pF1KE0487
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0487, 357 aa
  1>>>pF1KE0487 357 - 357 aa - 357 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0755+/-0.000358; mu= 17.9756+/- 0.022
 mean_var=63.0132+/-12.513, 0's: 0 Z-trim(112.4): 14  B-trim: 0 in 0/55
 Lambda= 0.161569
 statistics sampled from 21310 (21319) to 21310 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.25), width:  16
 Scan time:  6.850

The best scores are:                                      opt bits E(85289)
XP_016873774 (OMIM: 616587) PREDICTED: protein FAM ( 350) 1025 247.6 3.2e-65
NP_001317375 (OMIM: 616587) protein FAM118B isofor ( 350) 1025 247.6 3.2e-65
XP_011541279 (OMIM: 616587) PREDICTED: protein FAM ( 351) 1025 247.6 3.2e-65
NP_078832 (OMIM: 616587) protein FAM118B isoform 1 ( 351) 1025 247.6 3.2e-65
XP_016873775 (OMIM: 616587) PREDICTED: protein FAM ( 195)  471 118.3 1.5e-26
XP_011541280 (OMIM: 616587) PREDICTED: protein FAM ( 196)  471 118.3 1.5e-26


>>XP_016873774 (OMIM: 616587) PREDICTED: protein FAM118B  (350 aa)
 initn: 1065 init1: 639 opt: 1025  Z-score: 1292.0  bits: 247.6 E(85289): 3.2e-65
Smith-Waterman score: 1025; 52.4% identity (81.1% similar) in 296 aa overlap (13-306:26-321)

                            10        20        30        40       
pF1KE0              MDSVEKTTNRSEQKSRKFLKSLIRKQPQELLLVIGTGVSAAVAPGIP
                                .: ::.: ::  :.:.::.::::::.:::::: .:
XP_016 MASTGSQASDIDEIFGFFNDGEPPTKKPRKLLPSLKTKKPRELVLVIGTGISAAVAPQVP
               10        20        30        40        50        60

        50        60        70        80        90       100       
pF1KE0 ALCSWRSCIEAVIEAAEQLEVLHPGDVAEFRRKVTKDRDLLVVAHDLIRKMSPRTGDAKP
       :: ::.. :.:...:: ....:.  .  .:.. . .:..:. ::::::.:.::::.... 
XP_016 ALKSWKGLIQALLDAAIDFDLLEDEESKKFQKCLHEDKNLVHVAHDLIQKLSPRTSNVRS
               70        80        90       100       110       120

       110       120         130       140       150       160     
pF1KE0 SFFQDCLMEVFDDLEQHIRSP--LVLQSILSLMDRGAMVLTTNYDNLLEAFGRRQNKPME
       .::.:::.:::::::.....    .:::.: ::. ::.:::::.::::: ..  :.: .:
XP_016 TFFKDCLYEVFDDLESKMEDSGKQLLQSVLHLMENGALVLTTNFDNLLELYAADQGKQLE
              130       140       150       160       170       180

         170       180       190       200       210       220     
pF1KE0 SLDLKDKTKVLEWARGHMKYGVLHIHGLYTDPCGVVLDPSGYKDVTQDAEVMEVLQNLYR
       :::: :. ::::::. . : .::::::.::.: :.:: :.::..: ...:::. .:.::.
XP_016 SLDLTDEKKVLEWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYE
              190       200       210       220       230       240

         230       240       250       260       270       280     
pF1KE0 TKSFLFVGCGETLHDQIFQALFLYSVPNKVDLEHYMLVLKENEDHFFKHQADMLLHGIKV
       .:::::.::: :. :  :::::: .: .: ::::.::: . . :.: : . .:: .::::
XP_016 NKSFLFLGCGWTVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKV
              250       260       270       280       290       300

         290       300       310       320       330       340     
pF1KE0 VSYGDCFDHFPGYVQDLATQICKQQSPDADRVDSTTLLGNACQDCAKRKLEENGIEVSKK
       .:::: .  .: : . :. .:                                       
XP_016 ISYGDDYADLPEYFKRLTCEISTRGTSGMVREGQLNGSSAAHSEIRGCST          
              310       320       330       340       350          

>>NP_001317375 (OMIM: 616587) protein FAM118B isoform 2   (350 aa)
 initn: 1065 init1: 639 opt: 1025  Z-score: 1292.0  bits: 247.6 E(85289): 3.2e-65
Smith-Waterman score: 1025; 52.4% identity (81.1% similar) in 296 aa overlap (13-306:26-321)

                            10        20        30        40       
pF1KE0              MDSVEKTTNRSEQKSRKFLKSLIRKQPQELLLVIGTGVSAAVAPGIP
                                .: ::.: ::  :.:.::.::::::.:::::: .:
NP_001 MASTGSQASDIDEIFGFFNDGEPPTKKPRKLLPSLKTKKPRELVLVIGTGISAAVAPQVP
               10        20        30        40        50        60

        50        60        70        80        90       100       
pF1KE0 ALCSWRSCIEAVIEAAEQLEVLHPGDVAEFRRKVTKDRDLLVVAHDLIRKMSPRTGDAKP
       :: ::.. :.:...:: ....:.  .  .:.. . .:..:. ::::::.:.::::.... 
NP_001 ALKSWKGLIQALLDAAIDFDLLEDEESKKFQKCLHEDKNLVHVAHDLIQKLSPRTSNVRS
               70        80        90       100       110       120

       110       120         130       140       150       160     
pF1KE0 SFFQDCLMEVFDDLEQHIRSP--LVLQSILSLMDRGAMVLTTNYDNLLEAFGRRQNKPME
       .::.:::.:::::::.....    .:::.: ::. ::.:::::.::::: ..  :.: .:
NP_001 TFFKDCLYEVFDDLESKMEDSGKQLLQSVLHLMENGALVLTTNFDNLLELYAADQGKQLE
              130       140       150       160       170       180

         170       180       190       200       210       220     
pF1KE0 SLDLKDKTKVLEWARGHMKYGVLHIHGLYTDPCGVVLDPSGYKDVTQDAEVMEVLQNLYR
       :::: :. ::::::. . : .::::::.::.: :.:: :.::..: ...:::. .:.::.
NP_001 SLDLTDEKKVLEWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYE
              190       200       210       220       230       240

         230       240       250       260       270       280     
pF1KE0 TKSFLFVGCGETLHDQIFQALFLYSVPNKVDLEHYMLVLKENEDHFFKHQADMLLHGIKV
       .:::::.::: :. :  :::::: .: .: ::::.::: . . :.: : . .:: .::::
NP_001 NKSFLFLGCGWTVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKV
              250       260       270       280       290       300

         290       300       310       320       330       340     
pF1KE0 VSYGDCFDHFPGYVQDLATQICKQQSPDADRVDSTTLLGNACQDCAKRKLEENGIEVSKK
       .:::: .  .: : . :. .:                                       
NP_001 ISYGDDYADLPEYFKRLTCEISTRGTSGMVREGQLNGSSAAHSEIRGCST          
              310       320       330       340       350          

>>XP_011541279 (OMIM: 616587) PREDICTED: protein FAM118B  (351 aa)
 initn: 1065 init1: 639 opt: 1025  Z-score: 1291.9  bits: 247.6 E(85289): 3.2e-65
Smith-Waterman score: 1025; 52.4% identity (81.1% similar) in 296 aa overlap (13-306:26-321)

                            10        20        30        40       
pF1KE0              MDSVEKTTNRSEQKSRKFLKSLIRKQPQELLLVIGTGVSAAVAPGIP
                                .: ::.: ::  :.:.::.::::::.:::::: .:
XP_011 MASTGSQASDIDEIFGFFNDGEPPTKKPRKLLPSLKTKKPRELVLVIGTGISAAVAPQVP
               10        20        30        40        50        60

        50        60        70        80        90       100       
pF1KE0 ALCSWRSCIEAVIEAAEQLEVLHPGDVAEFRRKVTKDRDLLVVAHDLIRKMSPRTGDAKP
       :: ::.. :.:...:: ....:.  .  .:.. . .:..:. ::::::.:.::::.... 
XP_011 ALKSWKGLIQALLDAAIDFDLLEDEESKKFQKCLHEDKNLVHVAHDLIQKLSPRTSNVRS
               70        80        90       100       110       120

       110       120         130       140       150       160     
pF1KE0 SFFQDCLMEVFDDLEQHIRSP--LVLQSILSLMDRGAMVLTTNYDNLLEAFGRRQNKPME
       .::.:::.:::::::.....    .:::.: ::. ::.:::::.::::: ..  :.: .:
XP_011 TFFKDCLYEVFDDLESKMEDSGKQLLQSVLHLMENGALVLTTNFDNLLELYAADQGKQLE
              130       140       150       160       170       180

         170       180       190       200       210       220     
pF1KE0 SLDLKDKTKVLEWARGHMKYGVLHIHGLYTDPCGVVLDPSGYKDVTQDAEVMEVLQNLYR
       :::: :. ::::::. . : .::::::.::.: :.:: :.::..: ...:::. .:.::.
XP_011 SLDLTDEKKVLEWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYE
              190       200       210       220       230       240

         230       240       250       260       270       280     
pF1KE0 TKSFLFVGCGETLHDQIFQALFLYSVPNKVDLEHYMLVLKENEDHFFKHQADMLLHGIKV
       .:::::.::: :. :  :::::: .: .: ::::.::: . . :.: : . .:: .::::
XP_011 NKSFLFLGCGWTVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKV
              250       260       270       280       290       300

         290       300       310       320       330       340     
pF1KE0 VSYGDCFDHFPGYVQDLATQICKQQSPDADRVDSTTLLGNACQDCAKRKLEENGIEVSKK
       .:::: .  .: : . :. .:                                       
XP_011 ISYGDDYADLPEYFKRLTCEISTRGTSAGMVREGQLNGSSAAHSEIRGCST         
              310       320       330       340       350          

>>NP_078832 (OMIM: 616587) protein FAM118B isoform 1 [Ho  (351 aa)
 initn: 1065 init1: 639 opt: 1025  Z-score: 1291.9  bits: 247.6 E(85289): 3.2e-65
Smith-Waterman score: 1025; 52.4% identity (81.1% similar) in 296 aa overlap (13-306:26-321)

                            10        20        30        40       
pF1KE0              MDSVEKTTNRSEQKSRKFLKSLIRKQPQELLLVIGTGVSAAVAPGIP
                                .: ::.: ::  :.:.::.::::::.:::::: .:
NP_078 MASTGSQASDIDEIFGFFNDGEPPTKKPRKLLPSLKTKKPRELVLVIGTGISAAVAPQVP
               10        20        30        40        50        60

        50        60        70        80        90       100       
pF1KE0 ALCSWRSCIEAVIEAAEQLEVLHPGDVAEFRRKVTKDRDLLVVAHDLIRKMSPRTGDAKP
       :: ::.. :.:...:: ....:.  .  .:.. . .:..:. ::::::.:.::::.... 
NP_078 ALKSWKGLIQALLDAAIDFDLLEDEESKKFQKCLHEDKNLVHVAHDLIQKLSPRTSNVRS
               70        80        90       100       110       120

       110       120         130       140       150       160     
pF1KE0 SFFQDCLMEVFDDLEQHIRSP--LVLQSILSLMDRGAMVLTTNYDNLLEAFGRRQNKPME
       .::.:::.:::::::.....    .:::.: ::. ::.:::::.::::: ..  :.: .:
NP_078 TFFKDCLYEVFDDLESKMEDSGKQLLQSVLHLMENGALVLTTNFDNLLELYAADQGKQLE
              130       140       150       160       170       180

         170       180       190       200       210       220     
pF1KE0 SLDLKDKTKVLEWARGHMKYGVLHIHGLYTDPCGVVLDPSGYKDVTQDAEVMEVLQNLYR
       :::: :. ::::::. . : .::::::.::.: :.:: :.::..: ...:::. .:.::.
NP_078 SLDLTDEKKVLEWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYE
              190       200       210       220       230       240

         230       240       250       260       270       280     
pF1KE0 TKSFLFVGCGETLHDQIFQALFLYSVPNKVDLEHYMLVLKENEDHFFKHQADMLLHGIKV
       .:::::.::: :. :  :::::: .: .: ::::.::: . . :.: : . .:: .::::
NP_078 NKSFLFLGCGWTVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKV
              250       260       270       280       290       300

         290       300       310       320       330       340     
pF1KE0 VSYGDCFDHFPGYVQDLATQICKQQSPDADRVDSTTLLGNACQDCAKRKLEENGIEVSKK
       .:::: .  .: : . :. .:                                       
NP_078 ISYGDDYADLPEYFKRLTCEISTRGTSAGMVREGQLNGSSAAHSEIRGCST         
              310       320       330       340       350          

>>XP_016873775 (OMIM: 616587) PREDICTED: protein FAM118B  (195 aa)
 initn: 493 init1: 468 opt: 471  Z-score: 597.8  bits: 118.3 E(85289): 1.5e-26
Smith-Waterman score: 471; 47.5% identity (73.1% similar) in 160 aa overlap (148-306:7-166)

       120       130       140       150       160        170      
pF1KE0 FDDLEQHIRSPLVLQSILSLMDRGAMVLTTNYDNLLEAFGRRQNKPMES-LDLKDKTKVL
                                     :  : :  . :.. . . : :     ..::
XP_016                         MQQIRGNSLNPLTLLMRKRCSALPSWLGYMCVVQVL
                                       10        20        30      

        180       190       200       210       220       230      
pF1KE0 EWARGHMKYGVLHIHGLYTDPCGVVLDPSGYKDVTQDAEVMEVLQNLYRTKSFLFVGCGE
       :::. . : .::::::.::.: :.:: :.::..: ...:::. .:.::..:::::.::: 
XP_016 EWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYENKSFLFLGCGW
         40        50        60        70        80        90      

        240       250       260       270       280       290      
pF1KE0 TLHDQIFQALFLYSVPNKVDLEHYMLVLKENEDHFFKHQADMLLHGIKVVSYGDCFDHFP
       :. :  :::::: .: .: ::::.::: . . :.: : . .:: .::::.:::: .  .:
XP_016 TVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKVISYGDDYADLP
        100       110       120       130       140       150      

        300       310       320       330       340       350      
pF1KE0 GYVQDLATQICKQQSPDADRVDSTTLLGNACQDCAKRKLEENGIEVSKKRTQSDTDDAGG
        : . :. .:                                                  
XP_016 EYFKRLTCEISTRGTSGMVREGQLNGSSAAHSEIRGCST                     
        160       170       180       190                          

>>XP_011541280 (OMIM: 616587) PREDICTED: protein FAM118B  (196 aa)
 initn: 493 init1: 468 opt: 471  Z-score: 597.8  bits: 118.3 E(85289): 1.5e-26
Smith-Waterman score: 471; 47.5% identity (73.1% similar) in 160 aa overlap (148-306:7-166)

       120       130       140       150       160        170      
pF1KE0 FDDLEQHIRSPLVLQSILSLMDRGAMVLTTNYDNLLEAFGRRQNKPMES-LDLKDKTKVL
                                     :  : :  . :.. . . : :     ..::
XP_011                         MQQIRGNSLNPLTLLMRKRCSALPSWLGYMCVVQVL
                                       10        20        30      

        180       190       200       210       220       230      
pF1KE0 EWARGHMKYGVLHIHGLYTDPCGVVLDPSGYKDVTQDAEVMEVLQNLYRTKSFLFVGCGE
       :::. . : .::::::.::.: :.:: :.::..: ...:::. .:.::..:::::.::: 
XP_011 EWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYENKSFLFLGCGW
         40        50        60        70        80        90      

        240       250       260       270       280       290      
pF1KE0 TLHDQIFQALFLYSVPNKVDLEHYMLVLKENEDHFFKHQADMLLHGIKVVSYGDCFDHFP
       :. :  :::::: .: .: ::::.::: . . :.: : . .:: .::::.:::: .  .:
XP_011 TVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKVISYGDDYADLP
        100       110       120       130       140       150      

        300       310       320       330       340       350      
pF1KE0 GYVQDLATQICKQQSPDADRVDSTTLLGNACQDCAKRKLEENGIEVSKKRTQSDTDDAGG
        : . :. .:                                                  
XP_011 EYFKRLTCEISTRGTSAGMVREGQLNGSSAAHSEIRGCST                    
        160       170       180       190                          




357 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 04:52:07 2016 done: Thu Nov  3 04:52:08 2016
 Total Scan time:  6.850 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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