Result of FASTA (omim) for
pF1KB5951
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5951, 510 aa
1>>>pF1KB5951 510 - 510 aa - 510 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.8615+/-0.000461; mu= -14.8365+/- 0.029
mean_var=566.8869+/-117.927, 0's: 0 Z-trim(123.9): 127 B-trim: 803 in 1/57
Lambda= 0.053867
statistics sampled from 44436 (44588) to 44436 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.523), width: 16
Scan time: 9.950
The best scores are: opt bits E(85289)
NP_004445 (OMIM: 601600) ETS translocation variant ( 510) 3685 301.1 5.2e-81
NP_001156623 (OMIM: 600541) ETS translocation vari ( 419) 1547 134.8 4.8e-31
NP_001156622 (OMIM: 600541) ETS translocation vari ( 437) 1547 134.8 4.9e-31
NP_001156621 (OMIM: 600541) ETS translocation vari ( 459) 1547 134.9 5.1e-31
NP_001156620 (OMIM: 600541) ETS translocation vari ( 459) 1547 134.9 5.1e-31
XP_011513472 (OMIM: 600541) PREDICTED: ETS translo ( 472) 1547 134.9 5.2e-31
XP_011513470 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1547 134.9 5.2e-31
XP_005249693 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1547 134.9 5.2e-31
XP_005249692 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1547 134.9 5.2e-31
NP_004947 (OMIM: 600541) ETS translocation variant ( 477) 1547 134.9 5.2e-31
XP_011513469 (OMIM: 600541) PREDICTED: ETS translo ( 491) 1547 134.9 5.3e-31
NP_001156624 (OMIM: 600541) ETS translocation vari ( 374) 1471 128.9 2.6e-29
XP_016879838 (OMIM: 600711) PREDICTED: ETS translo ( 479) 1246 111.5 5.7e-24
NP_001156619 (OMIM: 600541) ETS translocation vari ( 454) 1139 103.1 1.8e-21
NP_001248366 (OMIM: 600711) ETS translocation vari ( 445) 1121 101.7 4.6e-21
NP_001248367 (OMIM: 600711) ETS translocation vari ( 445) 1121 101.7 4.6e-21
NP_001977 (OMIM: 600711) ETS translocation variant ( 484) 1121 101.8 4.9e-21
NP_001073143 (OMIM: 600711) ETS translocation vari ( 484) 1121 101.8 4.9e-21
XP_011522816 (OMIM: 600711) PREDICTED: ETS translo ( 221) 968 89.5 1.1e-17
NP_001248368 (OMIM: 600711) ETS translocation vari ( 207) 954 88.4 2.2e-17
NP_001317380 (OMIM: 164720) protein C-ets-1 isofor ( 354) 430 47.9 5.7e-05
XP_016872806 (OMIM: 164720) PREDICTED: protein C-e ( 398) 430 48.0 6.2e-05
XP_011540953 (OMIM: 164720) PREDICTED: protein C-e ( 432) 430 48.0 6.6e-05
NP_001155894 (OMIM: 164720) protein C-ets-1 isofor ( 225) 421 47.0 6.8e-05
XP_016872805 (OMIM: 164720) PREDICTED: protein C-e ( 418) 421 47.3 0.0001
NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 ( 469) 422 47.4 0.00011
XP_005260992 (OMIM: 164740) PREDICTED: protein C-e ( 469) 422 47.4 0.00011
XP_016883779 (OMIM: 164740) PREDICTED: protein C-e ( 469) 422 47.4 0.00011
NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 ( 441) 421 47.3 0.00011
XP_016872804 (OMIM: 164720) PREDICTED: protein C-e ( 450) 421 47.3 0.00011
XP_011540952 (OMIM: 164720) PREDICTED: protein C-e ( 475) 421 47.4 0.00011
XP_016872803 (OMIM: 164720) PREDICTED: protein C-e ( 485) 421 47.4 0.00012
NP_001137292 (OMIM: 164720) protein C-ets-1 isofor ( 485) 421 47.4 0.00012
XP_011540951 (OMIM: 164720) PREDICTED: protein C-e ( 519) 421 47.4 0.00012
NP_001243224 (OMIM: 164740) protein C-ets-2 isofor ( 609) 422 47.6 0.00013
XP_011541004 (OMIM: 193067) PREDICTED: Friend leuk ( 410) 405 46.1 0.00024
NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259) 393 44.9 0.00034
NP_001257939 (OMIM: 193067) Friend leukemia integr ( 386) 393 45.1 0.00045
XP_016872894 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 393 45.1 0.00047
XP_016872895 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 393 45.1 0.00047
NP_001161153 (OMIM: 193067) Friend leukemia integr ( 419) 393 45.1 0.00047
XP_011541003 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 393 45.1 0.00047
NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238) 385 44.3 0.00049
NP_002008 (OMIM: 193067) Friend leukemia integrati ( 452) 393 45.2 0.0005
NP_001244097 (OMIM: 311040) ETS domain-containing ( 95) 369 42.6 0.00062
NP_001230358 (OMIM: 165080) transcriptional regula ( 363) 379 44.0 0.00091
NP_001129627 (OMIM: 165080) transcriptional regula ( 387) 379 44.0 0.00095
XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428) 379 44.1 0.001
XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435) 379 44.1 0.001
NP_001317954 (OMIM: 165080) transcriptional regula ( 455) 379 44.1 0.0011
>>NP_004445 (OMIM: 601600) ETS translocation variant 5 [ (510 aa)
initn: 3685 init1: 3685 opt: 3685 Z-score: 1575.3 bits: 301.1 E(85289): 5.2e-81
Smith-Waterman score: 3685; 100.0% identity (100.0% similar) in 510 aa overlap (1-510:1-510)
10 20 30 40 50 60
pF1KB5 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 AQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGANYGEKCLYNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSSCSHEQALGANYGEKCLYNY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 CAYDRKPPSGFKPLTPPTTPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQGVGPAPAPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CAYDRKPPSGFKPLTPPTTPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQGVGPAPAPHS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGVPGDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGVPGDNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPAHGFQSPMGIKQEPRDYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPAHGFQSPMGIKQEPRDYC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 VDSEVPNCQSSYMRGGYFSSSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VDSEVPNCQSSYMRGGYFSSSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 PYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 KLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECHLSEEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESECHLSEEDT
430 440 450 460 470 480
490 500 510
pF1KB5 LPLTHFEDSPAYLLDMDRCSSLPYAEGFAY
::::::::::::::::::::::::::::::
NP_004 LPLTHFEDSPAYLLDMDRCSSLPYAEGFAY
490 500 510
>>NP_001156623 (OMIM: 600541) ETS translocation variant (419 aa)
initn: 1569 init1: 1059 opt: 1547 Z-score: 678.4 bits: 134.8 E(85289): 4.8e-31
Smith-Waterman score: 1733; 59.1% identity (74.0% similar) in 450 aa overlap (69-510:11-419)
40 50 60 70 80 90
pF1KB5 LAHDSEELFQDLSQLQEAWLAEAQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSE
: : : .:: : :::.: ::: ::
NP_001 MLQDLSASVFFPPCSQHRTLVAFHGLPLKIKKEPHSPCSE
10 20 30 40
100 110 120 130 140 150
pF1KB5 LSS-CSHEQALGANYGEKCLYNYCAYDRKPPSGFKPLTPPT---TPLSPTHQNPLFPPPQ
.:: ::.:: . .:::::::: :::.:: :..: .::: ::.:: :
NP_001 ISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLH---------
50 60 70 80 90
160 170 180 190 200 210
pF1KB5 ATLPTSGHAPAAGPVQGVGPAPAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPS
:: .:.: : :.. .: . :: : . :...::
NP_001 -------HA-------------SPNSTHTPKPDR-AFPAHLPPSQSI------PDSSYPM
100 110 120
220 230 240 250 260 270
pF1KB5 EQRFQRQLSEPCHPFPPQPGVPGDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHG
..::.:::::::. ::: : .: ..:: :.:::::: .: ::::::::::::.:::.
NP_001 DHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPF---PPQGFKQEYHDPVYEHN
130 140 150 160 170 180
280 290 300 310 320 330
pF1KB5 VPGMPGPPA-HGFQSPMGIKQEPRDYCVDSEVPNCQSSYMRG-GYFS--SSHEGFSYEKD
. : : : ..: :. :::::::. :::::.:.: ::: :... : :: .::
NP_001 T--MVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKG
190 200 210 220 230
340 350 360 370 380 390
pF1KB5 PRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWT
:: ..::::::::...: .:::: :::::: ::::::::::::::.:::::.:.::::::
NP_001 PRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWT
240 250 260 270 280 290
400 410 420 430 440 450
pF1KB5 GRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCD
300 310 320 330 340 350
460 470 480 490 500 510
pF1KB5 PDALFSMAFPDNQRPFLKAESECHLSEEDTLPLTHFEDSPAYLLDMDRCSSLPYAEGFAY
:.:::::::::::::.::.. : :..::::.::.::..: ::. . :. :: ::..:
NP_001 PEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
360 370 380 390 400 410
>>NP_001156622 (OMIM: 600541) ETS translocation variant (437 aa)
initn: 1642 init1: 1059 opt: 1547 Z-score: 678.2 bits: 134.8 E(85289): 4.9e-31
Smith-Waterman score: 1812; 60.1% identity (76.0% similar) in 459 aa overlap (61-510:21-437)
40 50 60 70 80
pF1KB5 KRKFLDTDLAHDSEELFQDLSQLQEAWLAEAQVPD-DEQFVPDFQSDNLVLHAPPPTKIK
::::: :::::::.:...:..:. : :::
NP_001 MLQDLSASVFFPPCSQHRTLAQVPDNDEQFVPDYQAESLAFHGLP-LKIK
10 20 30 40
90 100 110 120 130 140
pF1KB5 RELHSPSSELSS-CSHEQALGANYGEKCLYNYCAYDRKPPSGFKPLTPPT---TPLSPTH
.: ::: ::.:: ::.:: . .:::::::: :::.:: :..: .::: ::.:: :
NP_001 KEPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLH
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB5 QNPLFPPPQATLPTSGHAPAAGPVQGVGPAPAPHSLPEPGPQQQTFAVPRPPHQPLQMPK
:: .:.: : :.. .: . :: : .
NP_001 ----------------HA-------------SPNSTHTPKPDR-AFPAHLPPSQSI----
110 120 130
210 220 230 240 250 260
pF1KB5 MMPENQYPSEQRFQRQLSEPCHPFPPQPGVPGDNRPSYHRQMSEPIVPAAPPPPQGFKQE
:...:: ..::.:::::::. ::: : .: ..:: :.:::::: .: ::::::::
NP_001 --PDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPF---PPQGFKQE
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB5 YHDPLYEHGVPGMPGPPA-HGFQSPMGIKQEPRDYCVDSEVPNCQSSYMRG-GYFS--SS
::::.:::.. : : : ..: :. :::::::. :::::.:.: ::: :... :
NP_001 YHDPVYEHNT--MVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSR
200 210 220 230 240
330 340 350 360 370 380
pF1KB5 HEGFSYEKDPRLYFDDTCVVPERLEGKVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDP
:: .:: :: ..::::::::...: .:::: :::::: ::::::::::::::.:::::
NP_001 TEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDP
250 260 270 280 290 300
390 400 410 420 430 440
pF1KB5 ANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGE
.:.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGE
310 320 330 340 350 360
450 460 470 480 490 500
pF1KB5 RYVYKFVCDPDALFSMAFPDNQRPFLKAESECHLSEEDTLPLTHFEDSPAYLLDMDRCSS
::::::::::.:::::::::::::.::.. : :..::::.::.::..: ::. . :.
NP_001 RYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNP
370 380 390 400 410 420
510
pF1KB5 LPYAEGFAY
:: ::..:
NP_001 HPYNEGYVY
430
>>NP_001156621 (OMIM: 600541) ETS translocation variant (459 aa)
initn: 1852 init1: 1059 opt: 1547 Z-score: 677.9 bits: 134.9 E(85289): 5.1e-31
Smith-Waterman score: 1971; 58.7% identity (74.5% similar) in 518 aa overlap (1-510:1-459)
10 20 30 40 50 60
pF1KB5 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAE
::::::::::.:: ...:...: .:. :::::.. ::::::::::::::::::.::::
NP_001 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSS-CSHEQALGANYGEKCLYN
...:. : :::.: ::: ::.:: ::.:: . .::::::::
NP_001 -----------------VAFHGLP-LKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
70 80 90 100
120 130 140 150 160 170
pF1KB5 YCAYDRKPPSGFKPLTPPT---TPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQGVGPAP
:::.:: :..: .::: ::.:: : ::
NP_001 VSAYDQKPQVGMRPSNPPTPSSTPVSPLH----------------HA-------------
110 120 130
180 190 200 210 220 230
pF1KB5 APHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGVP
.:.: : :.. .: . :: : .:...:: ..::.:::::::. ::: : .:
NP_001 SPNSTHTPKPDR-AFPAHLPPSQS------IPDSSYPMDHRFRRQLSEPCNSFPPLPTMP
140 150 160 170 180
240 250 260 270 280 290
pF1KB5 GDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPA-HGFQSPMGIKQE
..:: :.:::::: .: ::::::::::::.:::.. : : : ..: :. ::::
NP_001 REGRPMYQRQMSEPNIPF---PPQGFKQEYHDPVYEHNT--MVGSAASQSFPPPLMIKQE
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB5 PRDYCVDSEVPNCQSSYMRG-GYFS--SSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQE
:::. :::::.:.: ::: :... : :: .:: :: ..::::::::...: .:::
NP_001 PRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQE
250 260 270 280 290 300
360 370 380 390 400 410
pF1KB5 PTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQK
: :::::: ::::::::::::::.:::::.:.::::::::::::::::::::::::::::
NP_001 PGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQK
310 320 330 340 350 360
420 430 440 450 460 470
pF1KB5 NRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESE
:::::::::::::::::::::::::::::::::::::::.:::::::::::::.::.. :
NP_001 NRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDME
370 380 390 400 410 420
480 490 500 510
pF1KB5 CHLSEEDTLPLTHFEDSPAYLLDMDRCSSLPYAEGFAY
:..::::.::.::..: ::. . :. :: ::..:
NP_001 RHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
430 440 450
>>NP_001156620 (OMIM: 600541) ETS translocation variant (459 aa)
initn: 1852 init1: 1059 opt: 1547 Z-score: 677.9 bits: 134.9 E(85289): 5.1e-31
Smith-Waterman score: 1971; 58.7% identity (74.5% similar) in 518 aa overlap (1-510:1-459)
10 20 30 40 50 60
pF1KB5 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAE
::::::::::.:: ...:...: .:. :::::.. ::::::::::::::::::.::::
NP_001 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AQVPDDEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSS-CSHEQALGANYGEKCLYN
...:. : :::.: ::: ::.:: ::.:: . .::::::::
NP_001 -----------------VAFHGLP-LKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYN
70 80 90 100
120 130 140 150 160 170
pF1KB5 YCAYDRKPPSGFKPLTPPT---TPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQGVGPAP
:::.:: :..: .::: ::.:: : ::
NP_001 VSAYDQKPQVGMRPSNPPTPSSTPVSPLH----------------HA-------------
110 120 130
180 190 200 210 220 230
pF1KB5 APHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGVP
.:.: : :.. .: . :: : .:...:: ..::.:::::::. ::: : .:
NP_001 SPNSTHTPKPDR-AFPAHLPPSQS------IPDSSYPMDHRFRRQLSEPCNSFPPLPTMP
140 150 160 170 180
240 250 260 270 280 290
pF1KB5 GDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPA-HGFQSPMGIKQE
..:: :.:::::: .: ::::::::::::.:::.. : : : ..: :. ::::
NP_001 REGRPMYQRQMSEPNIPF---PPQGFKQEYHDPVYEHNT--MVGSAASQSFPPPLMIKQE
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB5 PRDYCVDSEVPNCQSSYMRG-GYFS--SSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQE
:::. :::::.:.: ::: :... : :: .:: :: ..::::::::...: .:::
NP_001 PRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQE
250 260 270 280 290 300
360 370 380 390 400 410
pF1KB5 PTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQK
: :::::: ::::::::::::::.:::::.:.::::::::::::::::::::::::::::
NP_001 PGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQK
310 320 330 340 350 360
420 430 440 450 460 470
pF1KB5 NRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAESE
:::::::::::::::::::::::::::::::::::::::.:::::::::::::.::.. :
NP_001 NRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDME
370 380 390 400 410 420
480 490 500 510
pF1KB5 CHLSEEDTLPLTHFEDSPAYLLDMDRCSSLPYAEGFAY
:..::::.::.::..: ::. . :. :: ::..:
NP_001 RHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
430 440 450
>>XP_011513472 (OMIM: 600541) PREDICTED: ETS translocati (472 aa)
initn: 1706 init1: 1059 opt: 1547 Z-score: 677.8 bits: 134.9 E(85289): 5.2e-31
Smith-Waterman score: 2025; 60.5% identity (76.6% similar) in 512 aa overlap (9-510:3-472)
10 20 30 40 50
pF1KB5 MDGFYDQQVPFMVPGKS-RSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLA
.:: :: :...: .:. :::::.. ::::::::::::::::::.:::
XP_011 MSLPFSDLDKSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLA
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 EAQVPD-DEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSS-CSHEQALGANYGEKCL
:::::: :::::::.:...:..:. : :::.: ::: ::.:: ::.:: . .::::::
XP_011 EAQVPDNDEQFVPDYQAESLAFHGLP-LKIKKEPHSPCSEISSACSQEQPFKFSYGEKCL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 YNYCAYDRKPPSGFKPLTPPT---TPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQGVGP
:: :::.:: :..: .::: ::.:: : ::
XP_011 YNVSAYDQKPQVGMRPSNPPTPSSTPVSPLH----------------HA-----------
120 130 140
180 190 200 210 220 230
pF1KB5 APAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPG
.:.: : :.. .: . :: : . :...:: ..::.:::::::. ::: :
XP_011 --SPNSTHTPKPDR-AFPAHLPPSQSI------PDSSYPMDHRFRRQLSEPCNSFPPLPT
150 160 170 180 190
240 250 260 270 280 290
pF1KB5 VPGDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPA-HGFQSPMGIK
.: ..:: :.:::::: .: ::::::::::::.:::.. : : : ..: :. ::
XP_011 MPREGRPMYQRQMSEPNIPF---PPQGFKQEYHDPVYEHNT--MVGSAASQSFPPPLMIK
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB5 QEPRDYCVDSEVPNCQSSYMRG-GYFS--SSHEGFSYEKDPRLYFDDTCVVPERLEGKVK
:::::. :::::.:.: ::: :... : :: .:: :: ..::::::::...: .:
XP_011 QEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIK
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB5 QEPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGI
::: :::::: ::::::::::::::.:::::.:.::::::::::::::::::::::::::
XP_011 QEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGI
320 330 340 350 360 370
420 430 440 450 460 470
pF1KB5 QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAE
:::::::::::::::::::::::::::::::::::::::::.:::::::::::::.::..
XP_011 QKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTD
380 390 400 410 420 430
480 490 500 510
pF1KB5 SECHLSEEDTLPLTHFEDSPAYLLDMDRCSSLPYAEGFAY
: :..::::.::.::..: ::. . :. :: ::..:
XP_011 MERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
440 450 460 470
>>XP_011513470 (OMIM: 600541) PREDICTED: ETS translocati (477 aa)
initn: 1819 init1: 1059 opt: 1547 Z-score: 677.7 bits: 134.9 E(85289): 5.2e-31
Smith-Waterman score: 2109; 61.3% identity (77.6% similar) in 519 aa overlap (1-510:1-477)
10 20 30 40 50 60
pF1KB5 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAE
::::::::::.:: ...:...: .:. :::::.. ::::::::::::::::::.::::
XP_011 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AQVPD-DEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSS-CSHEQALGANYGEKCLY
::::: :::::::.:...:..:. : :::.: ::: ::.:: ::.:: . .:::::::
XP_011 AQVPDNDEQFVPDYQAESLAFHGLP-LKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLY
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 NYCAYDRKPPSGFKPLTPPT---TPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQGVGPA
: :::.:: :..: .::: ::.:: : ::
XP_011 NVSAYDQKPQVGMRPSNPPTPSSTPVSPLH----------------HA------------
120 130 140 150
180 190 200 210 220 230
pF1KB5 PAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGV
.:.: : :.. .: . :: : .:...:: ..::.:::::::. ::: : .
XP_011 -SPNSTHTPKPDR-AFPAHLPPSQS------IPDSSYPMDHRFRRQLSEPCNSFPPLPTM
160 170 180 190 200
240 250 260 270 280 290
pF1KB5 PGDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPA-HGFQSPMGIKQ
: ..:: :.:::::: .: ::::::::::::.:::.. : : : ..: :. :::
XP_011 PREGRPMYQRQMSEPNIPF---PPQGFKQEYHDPVYEHNT--MVGSAASQSFPPPLMIKQ
210 220 230 240 250
300 310 320 330 340 350
pF1KB5 EPRDYCVDSEVPNCQSSYMRG-GYFS--SSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQ
::::. :::::.:.: ::: :... : :: .:: :: ..::::::::...: .::
XP_011 EPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQ
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB5 EPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQ
:: :::::: ::::::::::::::.:::::.:.:::::::::::::::::::::::::::
XP_011 EPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQ
320 330 340 350 360 370
420 430 440 450 460 470
pF1KB5 KNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAES
::::::::::::::::::::::::::::::::::::::::.:::::::::::::.::..
XP_011 KNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDM
380 390 400 410 420 430
480 490 500 510
pF1KB5 ECHLSEEDTLPLTHFEDSPAYLLDMDRCSSLPYAEGFAY
: :..::::.::.::..: ::. . :. :: ::..:
XP_011 ERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
440 450 460 470
>>XP_005249693 (OMIM: 600541) PREDICTED: ETS translocati (477 aa)
initn: 1819 init1: 1059 opt: 1547 Z-score: 677.7 bits: 134.9 E(85289): 5.2e-31
Smith-Waterman score: 2109; 61.3% identity (77.6% similar) in 519 aa overlap (1-510:1-477)
10 20 30 40 50 60
pF1KB5 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAE
::::::::::.:: ...:...: .:. :::::.. ::::::::::::::::::.::::
XP_005 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AQVPD-DEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSS-CSHEQALGANYGEKCLY
::::: :::::::.:...:..:. : :::.: ::: ::.:: ::.:: . .:::::::
XP_005 AQVPDNDEQFVPDYQAESLAFHGLP-LKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLY
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 NYCAYDRKPPSGFKPLTPPT---TPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQGVGPA
: :::.:: :..: .::: ::.:: : ::
XP_005 NVSAYDQKPQVGMRPSNPPTPSSTPVSPLH----------------HA------------
120 130 140 150
180 190 200 210 220 230
pF1KB5 PAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGV
.:.: : :.. .: . :: : .:...:: ..::.:::::::. ::: : .
XP_005 -SPNSTHTPKPDR-AFPAHLPPSQS------IPDSSYPMDHRFRRQLSEPCNSFPPLPTM
160 170 180 190 200
240 250 260 270 280 290
pF1KB5 PGDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPA-HGFQSPMGIKQ
: ..:: :.:::::: .: ::::::::::::.:::.. : : : ..: :. :::
XP_005 PREGRPMYQRQMSEPNIPF---PPQGFKQEYHDPVYEHNT--MVGSAASQSFPPPLMIKQ
210 220 230 240 250
300 310 320 330 340 350
pF1KB5 EPRDYCVDSEVPNCQSSYMRG-GYFS--SSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQ
::::. :::::.:.: ::: :... : :: .:: :: ..::::::::...: .::
XP_005 EPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQ
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB5 EPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQ
:: :::::: ::::::::::::::.:::::.:.:::::::::::::::::::::::::::
XP_005 EPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQ
320 330 340 350 360 370
420 430 440 450 460 470
pF1KB5 KNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAES
::::::::::::::::::::::::::::::::::::::::.:::::::::::::.::..
XP_005 KNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDM
380 390 400 410 420 430
480 490 500 510
pF1KB5 ECHLSEEDTLPLTHFEDSPAYLLDMDRCSSLPYAEGFAY
: :..::::.::.::..: ::. . :. :: ::..:
XP_005 ERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
440 450 460 470
>>XP_005249692 (OMIM: 600541) PREDICTED: ETS translocati (477 aa)
initn: 1819 init1: 1059 opt: 1547 Z-score: 677.7 bits: 134.9 E(85289): 5.2e-31
Smith-Waterman score: 2109; 61.3% identity (77.6% similar) in 519 aa overlap (1-510:1-477)
10 20 30 40 50 60
pF1KB5 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAE
::::::::::.:: ...:...: .:. :::::.. ::::::::::::::::::.::::
XP_005 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AQVPD-DEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSS-CSHEQALGANYGEKCLY
::::: :::::::.:...:..:. : :::.: ::: ::.:: ::.:: . .:::::::
XP_005 AQVPDNDEQFVPDYQAESLAFHGLP-LKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLY
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 NYCAYDRKPPSGFKPLTPPT---TPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQGVGPA
: :::.:: :..: .::: ::.:: : ::
XP_005 NVSAYDQKPQVGMRPSNPPTPSSTPVSPLH----------------HA------------
120 130 140 150
180 190 200 210 220 230
pF1KB5 PAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGV
.:.: : :.. .: . :: : .:...:: ..::.:::::::. ::: : .
XP_005 -SPNSTHTPKPDR-AFPAHLPPSQS------IPDSSYPMDHRFRRQLSEPCNSFPPLPTM
160 170 180 190 200
240 250 260 270 280 290
pF1KB5 PGDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPA-HGFQSPMGIKQ
: ..:: :.:::::: .: ::::::::::::.:::.. : : : ..: :. :::
XP_005 PREGRPMYQRQMSEPNIPF---PPQGFKQEYHDPVYEHNT--MVGSAASQSFPPPLMIKQ
210 220 230 240 250
300 310 320 330 340 350
pF1KB5 EPRDYCVDSEVPNCQSSYMRG-GYFS--SSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQ
::::. :::::.:.: ::: :... : :: .:: :: ..::::::::...: .::
XP_005 EPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQ
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB5 EPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQ
:: :::::: ::::::::::::::.:::::.:.:::::::::::::::::::::::::::
XP_005 EPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQ
320 330 340 350 360 370
420 430 440 450 460 470
pF1KB5 KNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAES
::::::::::::::::::::::::::::::::::::::::.:::::::::::::.::..
XP_005 KNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDM
380 390 400 410 420 430
480 490 500 510
pF1KB5 ECHLSEEDTLPLTHFEDSPAYLLDMDRCSSLPYAEGFAY
: :..::::.::.::..: ::. . :. :: ::..:
XP_005 ERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
440 450 460 470
>>NP_004947 (OMIM: 600541) ETS translocation variant 1 i (477 aa)
initn: 1819 init1: 1059 opt: 1547 Z-score: 677.7 bits: 134.9 E(85289): 5.2e-31
Smith-Waterman score: 2109; 61.3% identity (77.6% similar) in 519 aa overlap (1-510:1-477)
10 20 30 40 50 60
pF1KB5 MDGFYDQQVPFMVPGKSRSEECRGRPVIDRKRKFLDTDLAHDSEELFQDLSQLQEAWLAE
::::::::::.:: ...:...: .:. :::::.. ::::::::::::::::::.::::
NP_004 MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAE
10 20 30 40 50 60
70 80 90 100 110
pF1KB5 AQVPD-DEQFVPDFQSDNLVLHAPPPTKIKRELHSPSSELSS-CSHEQALGANYGEKCLY
::::: :::::::.:...:..:. : :::.: ::: ::.:: ::.:: . .:::::::
NP_004 AQVPDNDEQFVPDYQAESLAFHGLP-LKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLY
70 80 90 100 110
120 130 140 150 160 170
pF1KB5 NYCAYDRKPPSGFKPLTPPT---TPLSPTHQNPLFPPPQATLPTSGHAPAAGPVQGVGPA
: :::.:: :..: .::: ::.:: : ::
NP_004 NVSAYDQKPQVGMRPSNPPTPSSTPVSPLH----------------HA------------
120 130 140 150
180 190 200 210 220 230
pF1KB5 PAPHSLPEPGPQQQTFAVPRPPHQPLQMPKMMPENQYPSEQRFQRQLSEPCHPFPPQPGV
.:.: : :.. .: . :: : .:...:: ..::.:::::::. ::: : .
NP_004 -SPNSTHTPKPDR-AFPAHLPPSQS------IPDSSYPMDHRFRRQLSEPCNSFPPLPTM
160 170 180 190 200
240 250 260 270 280 290
pF1KB5 PGDNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLYEHGVPGMPGPPA-HGFQSPMGIKQ
: ..:: :.:::::: .: ::::::::::::.:::.. : : : ..: :. :::
NP_004 PREGRPMYQRQMSEPNIPF---PPQGFKQEYHDPVYEHNT--MVGSAASQSFPPPLMIKQ
210 220 230 240 250
300 310 320 330 340 350
pF1KB5 EPRDYCVDSEVPNCQSSYMRG-GYFS--SSHEGFSYEKDPRLYFDDTCVVPERLEGKVKQ
::::. :::::.:.: ::: :... : :: .:: :: ..::::::::...: .::
NP_004 EPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQ
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB5 EPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQ
:: :::::: ::::::::::::::.:::::.:.:::::::::::::::::::::::::::
NP_004 EPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQ
320 330 340 350 360 370
420 430 440 450 460 470
pF1KB5 KNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFLKAES
::::::::::::::::::::::::::::::::::::::::.:::::::::::::.::..
NP_004 KNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDM
380 390 400 410 420 430
480 490 500 510
pF1KB5 ECHLSEEDTLPLTHFEDSPAYLLDMDRCSSLPYAEGFAY
: :..::::.::.::..: ::. . :. :: ::..:
NP_004 ERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
440 450 460 470
510 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:37:08 2016 done: Fri Nov 4 21:37:10 2016
Total Scan time: 9.950 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]