Result of FASTA (omim) for pF1KB7738
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7738, 484 aa
  1>>>pF1KB7738 484 - 484 aa - 484 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.7587+/-0.00034; mu= 1.8507+/- 0.021
 mean_var=186.4875+/-38.549, 0's: 0 Z-trim(121.0): 155  B-trim: 0 in 0/54
 Lambda= 0.093918
 statistics sampled from 36846 (37008) to 36846 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.434), width:  16
 Scan time:  9.660

The best scores are:                                      opt bits E(85289)
NP_001073143 (OMIM: 600711) ETS translocation vari ( 484) 3431 477.2 4.5e-134
NP_001977 (OMIM: 600711) ETS translocation variant ( 484) 3431 477.2 4.5e-134
XP_016879838 (OMIM: 600711) PREDICTED: ETS translo ( 479) 3375 469.6 8.7e-132
NP_001248367 (OMIM: 600711) ETS translocation vari ( 445) 3173 442.2 1.4e-123
NP_001248366 (OMIM: 600711) ETS translocation vari ( 445) 3173 442.2 1.4e-123
XP_011513470 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1678 239.6 1.4e-62
NP_004947 (OMIM: 600541) ETS translocation variant ( 477) 1678 239.6 1.4e-62
XP_005249693 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1678 239.6 1.4e-62
XP_005249692 (OMIM: 600541) PREDICTED: ETS translo ( 477) 1678 239.6 1.4e-62
XP_011513472 (OMIM: 600541) PREDICTED: ETS translo ( 472) 1653 236.3 1.5e-61
XP_011513469 (OMIM: 600541) PREDICTED: ETS translo ( 491) 1653 236.3 1.5e-61
NP_001156622 (OMIM: 600541) ETS translocation vari ( 437) 1543 221.3 4.3e-57
XP_011522816 (OMIM: 600711) PREDICTED: ETS translo ( 221) 1506 216.1 7.8e-56
NP_001248368 (OMIM: 600711) ETS translocation vari ( 207) 1457 209.5 7.4e-54
NP_001156623 (OMIM: 600541) ETS translocation vari ( 419) 1442 207.6 5.4e-53
NP_001156621 (OMIM: 600541) ETS translocation vari ( 459) 1438 207.1 8.5e-53
NP_001156620 (OMIM: 600541) ETS translocation vari ( 459) 1438 207.1 8.5e-53
NP_001156624 (OMIM: 600541) ETS translocation vari ( 374) 1271 184.4 4.7e-46
NP_004445 (OMIM: 601600) ETS translocation variant ( 510) 1121 164.2 7.9e-40
NP_001156619 (OMIM: 600541) ETS translocation vari ( 454) 1084 159.1 2.3e-38
NP_001155894 (OMIM: 164720) protein C-ets-1 isofor ( 225)  409 67.5 4.4e-11
NP_001317380 (OMIM: 164720) protein C-ets-1 isofor ( 354)  408 67.5 7.1e-11
XP_016872805 (OMIM: 164720) PREDICTED: protein C-e ( 418)  409 67.7 7.4e-11
NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 ( 441)  409 67.7 7.7e-11
XP_016872806 (OMIM: 164720) PREDICTED: protein C-e ( 398)  408 67.5 7.8e-11
XP_016872804 (OMIM: 164720) PREDICTED: protein C-e ( 450)  409 67.7 7.8e-11
XP_011540952 (OMIM: 164720) PREDICTED: protein C-e ( 475)  409 67.7 8.2e-11
XP_011540953 (OMIM: 164720) PREDICTED: protein C-e ( 432)  408 67.5 8.3e-11
NP_001137292 (OMIM: 164720) protein C-ets-1 isofor ( 485)  409 67.7 8.3e-11
XP_016872803 (OMIM: 164720) PREDICTED: protein C-e ( 485)  409 67.7 8.3e-11
XP_011540951 (OMIM: 164720) PREDICTED: protein C-e ( 519)  409 67.7 8.8e-11
XP_005260992 (OMIM: 164740) PREDICTED: protein C-e ( 469)  405 67.2 1.2e-10
XP_016883779 (OMIM: 164740) PREDICTED: protein C-e ( 469)  405 67.2 1.2e-10
NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 ( 469)  405 67.2 1.2e-10
NP_001243224 (OMIM: 164740) protein C-ets-2 isofor ( 609)  405 67.2 1.5e-10
NP_068567 (OMIM: 600246) ETS domain-containing pro ( 405)  389 64.9 4.7e-10
XP_016856069 (OMIM: 600246) PREDICTED: ETS domain- ( 413)  389 65.0 4.8e-10
NP_001244097 (OMIM: 311040) ETS domain-containing  (  95)  376 62.8 4.8e-10
XP_005245007 (OMIM: 600246) PREDICTED: ETS domain- ( 431)  389 65.0 4.9e-10
XP_005245008 (OMIM: 600246) PREDICTED: ETS domain- ( 431)  389 65.0 4.9e-10
NP_001964 (OMIM: 600246) ETS domain-containing pro ( 431)  389 65.0 4.9e-10
XP_016884828 (OMIM: 311040) PREDICTED: ETS domain- ( 428)  380 63.7 1.1e-09
NP_001107595 (OMIM: 311040) ETS domain-containing  ( 428)  380 63.7 1.1e-09
NP_005220 (OMIM: 311040) ETS domain-containing pro ( 428)  380 63.7 1.1e-09
XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428)  374 62.9   2e-09
XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435)  374 62.9   2e-09
NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238)  368 62.0 2.2e-09
NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259)  365 61.6 3.1e-09
NP_005221 (OMIM: 600247) ETS domain-containing pro ( 407)  367 62.0 3.7e-09
XP_006719338 (OMIM: 600247) PREDICTED: ETS domain- ( 407)  367 62.0 3.7e-09


>>NP_001073143 (OMIM: 600711) ETS translocation variant   (484 aa)
 initn: 3431 init1: 3431 opt: 3431  Z-score: 2527.9  bits: 477.2 E(85289): 4.5e-134
Smith-Waterman score: 3431; 100.0% identity (100.0% similar) in 484 aa overlap (1-484:1-484)

               10        20        30        40        50        60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
              430       440       450       460       470       480

           
pF1KB7 GYSY
       ::::
NP_001 GYSY
           

>>NP_001977 (OMIM: 600711) ETS translocation variant 4 i  (484 aa)
 initn: 3431 init1: 3431 opt: 3431  Z-score: 2527.9  bits: 477.2 E(85289): 4.5e-134
Smith-Waterman score: 3431; 100.0% identity (100.0% similar) in 484 aa overlap (1-484:1-484)

               10        20        30        40        50        60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
              430       440       450       460       470       480

           
pF1KB7 GYSY
       ::::
NP_001 GYSY
           

>>XP_016879838 (OMIM: 600711) PREDICTED: ETS translocati  (479 aa)
 initn: 2106 init1: 2082 opt: 3375  Z-score: 2487.0  bits: 469.6 E(85289): 8.7e-132
Smith-Waterman score: 3375; 99.0% identity (99.0% similar) in 484 aa overlap (1-484:1-479)

               10        20        30        40        50        60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEQCLYSSAYDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSSVFQQPLDICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYE
       :::::::::::::::::::::::::::::::::::::::::::::::::::     ::::
XP_016 AVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPG-----YGYE
              250       260       270       280       290          

              310       320       330       340       350       360
pF1KB7 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFI
         300       310       320       330       340       350     

              370       380       390       400       410       420
pF1KB7 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKF
         360       370       380       390       400       410     

              430       440       450       460       470       480
pF1KB7 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKG
         420       430       440       450       460       470     

           
pF1KB7 GYSY
       ::::
XP_016 GYSY
           

>>NP_001248367 (OMIM: 600711) ETS translocation variant   (445 aa)
 initn: 3173 init1: 3173 opt: 3173  Z-score: 2339.6  bits: 442.2 E(85289): 1.4e-123
Smith-Waterman score: 3173; 100.0% identity (100.0% similar) in 445 aa overlap (40-484:1-445)

      10        20        30        40        50        60         
pF1KB7 LDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MDPGSLPPLDSEDLFQDLSHFQETWLAEAQ
                                             10        20        30

      70        80        90       100       110       120         
pF1KB7 VPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSA
               40        50        60        70        80        90

     130       140       150       160       170       180         
pF1KB7 YDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPL
              100       110       120       130       140       150

     190       200       210       220       230       240         
pF1KB7 DICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNG
              160       170       180       190       200       210

     250       260       270       280       290       300         
pF1KB7 HRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYEKPLRPFPDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYEKPLRPFPDD
              220       230       240       250       260       270

     310       320       330       340       350       360         
pF1KB7 VCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEF
              280       290       300       310       320       330

     370       380       390       400       410       420         
pF1KB7 KLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFS
              340       350       360       370       380       390

     430       440       450       460       470       480    
pF1KB7 LAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY
              400       410       420       430       440     

>>NP_001248366 (OMIM: 600711) ETS translocation variant   (445 aa)
 initn: 3173 init1: 3173 opt: 3173  Z-score: 2339.6  bits: 442.2 E(85289): 1.4e-123
Smith-Waterman score: 3173; 100.0% identity (100.0% similar) in 445 aa overlap (40-484:1-445)

      10        20        30        40        50        60         
pF1KB7 LDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MDPGSLPPLDSEDLFQDLSHFQETWLAEAQ
                                             10        20        30

      70        80        90       100       110       120         
pF1KB7 VPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYSSA
               40        50        60        70        80        90

     130       140       150       160       170       180         
pF1KB7 YDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDPPRQIAIKSPAPGALGQSPLQPFPRAEQRNFLRSSGTSQPHPGHGYLGEHSSVFQQPL
              100       110       120       130       140       150

     190       200       210       220       230       240         
pF1KB7 DICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DICHSFTSQGGGREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGGVNG
              160       170       180       190       200       210

     250       260       270       280       290       300         
pF1KB7 HRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYEKPLRPFPDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGFSGPSPGDGAMGYGYEKPLRPFPDD
              220       230       240       250       260       270

     310       320       330       340       350       360         
pF1KB7 VCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGRGMEF
              280       290       300       310       320       330

     370       380       390       400       410       420         
pF1KB7 KLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPEALFS
              340       350       360       370       380       390

     430       440       450       460       470       480    
pF1KB7 LAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY
              400       410       420       430       440     

>>XP_011513470 (OMIM: 600541) PREDICTED: ETS translocati  (477 aa)
 initn: 1654 init1: 868 opt: 1678  Z-score: 1244.4  bits: 239.6 E(85289): 1.4e-62
Smith-Waterman score: 1683; 55.1% identity (74.3% similar) in 490 aa overlap (8-484:3-477)

               10        20        30        40        50        60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
              :. ::::::  .... : .  ..       :...  .:   :::.::::::..
XP_011      MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINR-DLAH-DSEELFQDLSQL
                    10        20        30         40         50   

               70        80        90       100       110       120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
       ::::::::::::.:::::::...:.::::.   .:::::.:: .. . .::.. :. . .
XP_011 QETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSY
            60        70        80        90       100       110   

               130       140       150                160       170
pF1KB7 GEQCLYS-SAYDPPRQIAIKSPAPGALGQSPLQPFPRAE---------QRNFLRSSGTSQ
       ::.:::. ::::   :....   : . ...:..:. .:          .: :      ::
XP_011 GEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQ
           120       130       140       150       160       170   

              180        190       200        210       220        
pF1KB7 PHPGHGYLGEHSSVFQQPL-DICHSFTSQGG-GREPLPAPYQHQLSEPCPPYPQQSFKQE
         :  .:  .:   :.. : . :.::       ::  :  ::.:.:::  :.: :.::::
XP_011 SIPDSSYPMDHR--FRRQLSEPCNSFPPLPTMPREGRPM-YQRQMSEPNIPFPPQGFKQE
           180         190       200       210        220       230

      230       240       250       260       270       280        
pF1KB7 YHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGF-SG
       ::::.::.  .     :.. .. .:   ..::::  ::::::.: .: :.:.. ::: . 
XP_011 YHDPVYEHNTMV----GSAASQSFPPP-LMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAH
              240           250        260       270       280     

       290       300       310       320       330       340       
pF1KB7 PSPGDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFL
       ::  .: :   .::  : : ::.:::::::.::::::  : .:::: :::::.:::::::
XP_011 PSRTEGCM---FEKGPRQFYDDTCVVPEKFDGDIKQEP-GMYREGPTYQRRGSLQLWQFL
         290          300       310       320        330       340 

       350       360       370       380       390       400       
pF1KB7 VALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGI
       :::::::.:.:::::::::::::::::::::: :::::::::::::::::::::::::::
XP_011 VALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGI
             350       360       370       380       390       400 

       410       420       430       440       450       460       
pF1KB7 MQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLP
       :::::::::::::::.::::::.:::::::: ::....: ..:::::::::.::: ::.:
XP_011 MQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMP
             410       420       430       440       450       460 

       470       480    
pF1KB7 ELAGPAQPFGPKGGYSY
       : .:  .:   . :: :
XP_011 E-GGCCNPHPYNEGYVY
              470       

>>NP_004947 (OMIM: 600541) ETS translocation variant 1 i  (477 aa)
 initn: 1654 init1: 868 opt: 1678  Z-score: 1244.4  bits: 239.6 E(85289): 1.4e-62
Smith-Waterman score: 1683; 55.1% identity (74.3% similar) in 490 aa overlap (8-484:3-477)

               10        20        30        40        50        60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
              :. ::::::  .... : .  ..       :...  .:   :::.::::::..
NP_004      MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINR-DLAH-DSEELFQDLSQL
                    10        20        30         40         50   

               70        80        90       100       110       120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
       ::::::::::::.:::::::...:.::::.   .:::::.:: .. . .::.. :. . .
NP_004 QETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSY
            60        70        80        90       100       110   

               130       140       150                160       170
pF1KB7 GEQCLYS-SAYDPPRQIAIKSPAPGALGQSPLQPFPRAE---------QRNFLRSSGTSQ
       ::.:::. ::::   :....   : . ...:..:. .:          .: :      ::
NP_004 GEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQ
           120       130       140       150       160       170   

              180        190       200        210       220        
pF1KB7 PHPGHGYLGEHSSVFQQPL-DICHSFTSQGG-GREPLPAPYQHQLSEPCPPYPQQSFKQE
         :  .:  .:   :.. : . :.::       ::  :  ::.:.:::  :.: :.::::
NP_004 SIPDSSYPMDHR--FRRQLSEPCNSFPPLPTMPREGRPM-YQRQMSEPNIPFPPQGFKQE
           180         190       200       210        220       230

      230       240       250       260       270       280        
pF1KB7 YHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGF-SG
       ::::.::.  .     :.. .. .:   ..::::  ::::::.: .: :.:.. ::: . 
NP_004 YHDPVYEHNTMV----GSAASQSFPPP-LMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAH
              240           250        260       270       280     

       290       300       310       320       330       340       
pF1KB7 PSPGDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFL
       ::  .: :   .::  : : ::.:::::::.::::::  : .:::: :::::.:::::::
NP_004 PSRTEGCM---FEKGPRQFYDDTCVVPEKFDGDIKQEP-GMYREGPTYQRRGSLQLWQFL
         290          300       310       320        330       340 

       350       360       370       380       390       400       
pF1KB7 VALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGI
       :::::::.:.:::::::::::::::::::::: :::::::::::::::::::::::::::
NP_004 VALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGI
             350       360       370       380       390       400 

       410       420       430       440       450       460       
pF1KB7 MQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLP
       :::::::::::::::.::::::.:::::::: ::....: ..:::::::::.::: ::.:
NP_004 MQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMP
             410       420       430       440       450       460 

       470       480    
pF1KB7 ELAGPAQPFGPKGGYSY
       : .:  .:   . :: :
NP_004 E-GGCCNPHPYNEGYVY
              470       

>>XP_005249693 (OMIM: 600541) PREDICTED: ETS translocati  (477 aa)
 initn: 1654 init1: 868 opt: 1678  Z-score: 1244.4  bits: 239.6 E(85289): 1.4e-62
Smith-Waterman score: 1683; 55.1% identity (74.3% similar) in 490 aa overlap (8-484:3-477)

               10        20        30        40        50        60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
              :. ::::::  .... : .  ..       :...  .:   :::.::::::..
XP_005      MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINR-DLAH-DSEELFQDLSQL
                    10        20        30         40         50   

               70        80        90       100       110       120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
       ::::::::::::.:::::::...:.::::.   .:::::.:: .. . .::.. :. . .
XP_005 QETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSY
            60        70        80        90       100       110   

               130       140       150                160       170
pF1KB7 GEQCLYS-SAYDPPRQIAIKSPAPGALGQSPLQPFPRAE---------QRNFLRSSGTSQ
       ::.:::. ::::   :....   : . ...:..:. .:          .: :      ::
XP_005 GEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQ
           120       130       140       150       160       170   

              180        190       200        210       220        
pF1KB7 PHPGHGYLGEHSSVFQQPL-DICHSFTSQGG-GREPLPAPYQHQLSEPCPPYPQQSFKQE
         :  .:  .:   :.. : . :.::       ::  :  ::.:.:::  :.: :.::::
XP_005 SIPDSSYPMDHR--FRRQLSEPCNSFPPLPTMPREGRPM-YQRQMSEPNIPFPPQGFKQE
           180         190       200       210        220       230

      230       240       250       260       270       280        
pF1KB7 YHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGF-SG
       ::::.::.  .     :.. .. .:   ..::::  ::::::.: .: :.:.. ::: . 
XP_005 YHDPVYEHNTMV----GSAASQSFPPP-LMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAH
              240           250        260       270       280     

       290       300       310       320       330       340       
pF1KB7 PSPGDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFL
       ::  .: :   .::  : : ::.:::::::.::::::  : .:::: :::::.:::::::
XP_005 PSRTEGCM---FEKGPRQFYDDTCVVPEKFDGDIKQEP-GMYREGPTYQRRGSLQLWQFL
         290          300       310       320        330       340 

       350       360       370       380       390       400       
pF1KB7 VALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGI
       :::::::.:.:::::::::::::::::::::: :::::::::::::::::::::::::::
XP_005 VALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGI
             350       360       370       380       390       400 

       410       420       430       440       450       460       
pF1KB7 MQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLP
       :::::::::::::::.::::::.:::::::: ::....: ..:::::::::.::: ::.:
XP_005 MQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMP
             410       420       430       440       450       460 

       470       480    
pF1KB7 ELAGPAQPFGPKGGYSY
       : .:  .:   . :: :
XP_005 E-GGCCNPHPYNEGYVY
              470       

>>XP_005249692 (OMIM: 600541) PREDICTED: ETS translocati  (477 aa)
 initn: 1654 init1: 868 opt: 1678  Z-score: 1244.4  bits: 239.6 E(85289): 1.4e-62
Smith-Waterman score: 1683; 55.1% identity (74.3% similar) in 490 aa overlap (8-484:3-477)

               10        20        30        40        50        60
pF1KB7 MERRMKAGYLDQQVPYTFSSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHF
              :. ::::::  .... : .  ..       :...  .:   :::.::::::..
XP_005      MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINR-DLAH-DSEELFQDLSQL
                    10        20        30         40         50   

               70        80        90       100       110       120
pF1KB7 QETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHH
       ::::::::::::.:::::::...:.::::.   .:::::.:: .. . .::.. :. . .
XP_005 QETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSY
            60        70        80        90       100       110   

               130       140       150                160       170
pF1KB7 GEQCLYS-SAYDPPRQIAIKSPAPGALGQSPLQPFPRAE---------QRNFLRSSGTSQ
       ::.:::. ::::   :....   : . ...:..:. .:          .: :      ::
XP_005 GEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQ
           120       130       140       150       160       170   

              180        190       200        210       220        
pF1KB7 PHPGHGYLGEHSSVFQQPL-DICHSFTSQGG-GREPLPAPYQHQLSEPCPPYPQQSFKQE
         :  .:  .:   :.. : . :.::       ::  :  ::.:.:::  :.: :.::::
XP_005 SIPDSSYPMDHR--FRRQLSEPCNSFPPLPTMPREGRPM-YQRQMSEPNIPFPPQGFKQE
           180         190       200       210        220       230

      230       240       250       260       270       280        
pF1KB7 YHDPLYEQAGQPAVDQGGVNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGF-SG
       ::::.::.  .     :.. .. .:   ..::::  ::::::.: .: :.:.. ::: . 
XP_005 YHDPVYEHNTMV----GSAASQSFPPP-LMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAH
              240           250        260       270       280     

       290       300       310       320       330       340       
pF1KB7 PSPGDGAMGYGYEKPLRPFPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFL
       ::  .: :   .::  : : ::.:::::::.::::::  : .:::: :::::.:::::::
XP_005 PSRTEGCM---FEKGPRQFYDDTCVVPEKFDGDIKQEP-GMYREGPTYQRRGSLQLWQFL
         290          300       310       320        330       340 

       350       360       370       380       390       400       
pF1KB7 VALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGI
       :::::::.:.:::::::::::::::::::::: :::::::::::::::::::::::::::
XP_005 VALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGI
             350       360       370       380       390       400 

       410       420       430       440       450       460       
pF1KB7 MQKVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLP
       :::::::::::::::.::::::.:::::::: ::....: ..:::::::::.::: ::.:
XP_005 MQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMP
             410       420       430       440       450       460 

       470       480    
pF1KB7 ELAGPAQPFGPKGGYSY
       : .:  .:   . :: :
XP_005 E-GGCCNPHPYNEGYVY
              470       

>>XP_011513472 (OMIM: 600541) PREDICTED: ETS translocati  (472 aa)
 initn: 1617 init1: 868 opt: 1653  Z-score: 1226.1  bits: 236.3 E(85289): 1.5e-61
Smith-Waterman score: 1658; 57.9% identity (76.2% similar) in 449 aa overlap (49-484:37-472)

       20        30        40        50        60        70        
pF1KB7 SSKSPGNGSLREALIGPLGKLMDPGSLPPLDSEDLFQDLSHFQETWLAEAQVPDSDEQFV
                                     :::.::::::..::::::::::::.:::::
XP_011 DLDKSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFV
         10        20        30        40        50        60      

       80        90       100       110       120        130       
pF1KB7 PDFHSENLAFHSPTTRIKKEPQSPRTDPALSCSRKPPLPYHHGEQCLYS-SAYDPPRQIA
       ::...:.::::.   .:::::.:: .. . .::.. :. . .::.:::. ::::   :..
XP_011 PDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVG
         70        80        90       100       110       120      

       140       150                160       170       180        
pF1KB7 IKSPAPGALGQSPLQPFPRAE---------QRNFLRSSGTSQPHPGHGYLGEHSSVFQQP
       ..   : . ...:..:. .:          .: :      ::  :  .:  .:   :.. 
XP_011 MRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHR--FRRQ
        130       140       150       160       170       180      

       190       200        210       220       230       240      
pF1KB7 L-DICHSFTSQGG-GREPLPAPYQHQLSEPCPPYPQQSFKQEYHDPLYEQAGQPAVDQGG
       : . :.::       ::  :  ::.:.:::  :.: :.::::::::.::.  .     :.
XP_011 LSEPCNSFPPLPTMPREGRPM-YQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMV----GS
          190       200        210       220       230             

        250       260       270       280        290       300     
pF1KB7 VNGHRYPGAGVVIKQEQTDFAYDSDVTGCASMYLHTEGF-SGPSPGDGAMGYGYEKPLRP
       . .. .:   ..::::  ::::::.: .: :.:.. ::: . ::  .: :   .::  : 
XP_011 AASQSFPPP-LMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCM---FEKGPRQ
     240        250       260       270       280          290     

         310       320       330       340       350       360     
pF1KB7 FPDDVCVVPEKFEGDIKQEGVGAFREGPPYQRRGALQLWQFLVALLDDPTNAHFIAWTGR
       : ::.:::::::.::::::  : .:::: :::::.::::::::::::::.:.::::::::
XP_011 FYDDTCVVPEKFDGDIKQEP-GMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGR
         300       310        320       330       340       350    

         370       380       390       400       410       420     
pF1KB7 GMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPE
       :::::::::::::: ::::::::::::::::::::::::::::::::::::::::::.::
XP_011 GMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPE
          360       370       380       390       400       410    

         430       440       450       460       470       480    
pF1KB7 ALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPELAGPAQPFGPKGGYSY
       ::::.:::::::: ::....: ..:::::::::.::: ::.:: .:  .:   . :: :
XP_011 ALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPE-GGCCNPHPYNEGYVY
          420       430       440       450        460       470  




484 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 01:03:20 2016 done: Sat Nov  5 01:03:22 2016
 Total Scan time:  9.660 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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