Result of FASTA (omim) for pF1KB6305
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6305, 258 aa
  1>>>pF1KB6305 258 - 258 aa - 258 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.8018+/-0.000362; mu= 17.5314+/- 0.023
 mean_var=64.8830+/-13.217, 0's: 0 Z-trim(113.5): 306  B-trim: 419 in 1/57
 Lambda= 0.159224
 statistics sampled from 22560 (22880) to 22560 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.268), width:  16
 Scan time:  5.720

The best scores are:                                      opt bits E(85289)
NP_001962 (OMIM: 130120) chymotrypsin-like elastas ( 258) 1753 411.3 8.8e-115
NP_254275 (OMIM: 609443) chymotrypsin-like elastas ( 269)  997 237.6 1.7e-62
NP_056933 (OMIM: 609444) chymotrypsin-like elastas ( 269)  962 229.6 4.5e-60
NP_009203 (OMIM: 167800,601405) chymotrypsin-C pre ( 268)  852 204.3 1.8e-52
NP_001898 (OMIM: 118888) chymotrypsin-like proteas ( 264)  617 150.3 3.2e-36
NP_001897 (OMIM: 118890) chymotrypsinogen B isofor ( 263)  552 135.4   1e-31
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436)  553 135.8 1.3e-31
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436)  553 135.8 1.3e-31
NP_000883 (OMIM: 229000,612423) plasma kallikrein  ( 638)  553 135.9 1.7e-31
XP_011530232 (OMIM: 229000,612423) PREDICTED: plas ( 649)  553 135.9 1.7e-31
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649)  553 135.9 1.7e-31
XP_005262880 (OMIM: 264900,612416) PREDICTED: coag ( 536)  548 134.7 3.3e-31
XP_006714200 (OMIM: 264900,612416) PREDICTED: coag ( 610)  548 134.8 3.6e-31
NP_000119 (OMIM: 264900,612416) coagulation factor ( 625)  548 134.8 3.7e-31
XP_005262878 (OMIM: 264900,612416) PREDICTED: coag ( 626)  548 134.8 3.7e-31
NP_000292 (OMIM: 173350,217090) plasminogen isofor ( 810)  548 134.9 4.5e-31
NP_001231924 (OMIM: 610050) transmembrane protease ( 563)  537 132.2   2e-30
NP_892028 (OMIM: 142440) serine protease hepsin pr ( 417)  535 131.7 2.1e-30
XP_016882220 (OMIM: 142440) PREDICTED: serine prot ( 417)  535 131.7 2.1e-30
XP_006723244 (OMIM: 142440) PREDICTED: serine prot ( 417)  535 131.7 2.1e-30
XP_005258895 (OMIM: 142440) PREDICTED: serine prot ( 417)  535 131.7 2.1e-30
NP_002142 (OMIM: 142440) serine protease hepsin pr ( 417)  535 131.7 2.1e-30
NP_001193718 (OMIM: 610050) transmembrane protease ( 532)  536 132.0 2.2e-30
NP_001070731 (OMIM: 610050) transmembrane protease ( 567)  536 132.0 2.3e-30
XP_016882221 (OMIM: 142440) PREDICTED: serine prot ( 393)  533 131.2 2.8e-30
NP_077078 (OMIM: 191081) tryptase beta-2 prepropro ( 275)  528 129.9 4.7e-30
NP_003285 (OMIM: 191080) tryptase alpha/beta-1 pre ( 275)  525 129.2 7.6e-30
NP_001243246 (OMIM: 605511) transmembrane protease ( 453)  509 125.7 1.4e-28
XP_005262454 (OMIM: 122700,300746,300807,306900) P ( 418)  508 125.5 1.6e-28
NP_001300842 (OMIM: 122700,300746,300807,306900) c ( 423)  508 125.5 1.6e-28
NP_000124 (OMIM: 122700,300746,300807,306900) coag ( 461)  508 125.5 1.7e-28
NP_001171131 (OMIM: 188050,603924,616535) hyaluron ( 534)  504 124.6 3.6e-28
NP_004123 (OMIM: 188050,603924,616535) hyaluronan- ( 560)  504 124.6 3.7e-28
XP_005255530 (OMIM: 609343) PREDICTED: brain-speci ( 317)  499 123.3 5.3e-28
NP_071402 (OMIM: 609343) brain-specific serine pro ( 317)  499 123.3 5.3e-28
NP_001277025 (OMIM: 606565) transmembrane protease ( 290)  497 122.8 6.9e-28
NP_115780 (OMIM: 605511) transmembrane protease se ( 327)  497 122.8 7.5e-28
NP_001167023 (OMIM: 606565) transmembrane protease ( 397)  497 122.9 8.7e-28
NP_001277023 (OMIM: 606565) transmembrane protease ( 412)  497 122.9   9e-28
NP_001077416 (OMIM: 606565) transmembrane protease ( 432)  497 122.9 9.3e-28
NP_001167022 (OMIM: 606565) transmembrane protease ( 435)  497 122.9 9.3e-28
NP_063947 (OMIM: 606565) transmembrane protease se ( 437)  497 122.9 9.4e-28
NP_076927 (OMIM: 605511) transmembrane protease se ( 454)  497 123.0 9.7e-28
NP_002760 (OMIM: 167800,276000,614044) trypsin-1 p ( 247)  493 121.8 1.1e-27
NP_003610 (OMIM: 249500,606709) neurotrypsin precu ( 875)  499 123.6 1.2e-27
XP_011514713 (OMIM: 167800,276000,614044) PREDICTE ( 472)  493 122.1 1.9e-27
XP_005271672 (OMIM: 606565) PREDICTED: transmembra ( 454)  485 120.2 6.5e-27
XP_011541204 (OMIM: 606565) PREDICTED: transmembra ( 456)  485 120.2 6.5e-27
XP_011541203 (OMIM: 606565) PREDICTED: transmembra ( 489)  485 120.2 6.9e-27
XP_005271671 (OMIM: 606565) PREDICTED: transmembra ( 492)  485 120.2 6.9e-27


>>NP_001962 (OMIM: 130120) chymotrypsin-like elastase fa  (258 aa)
 initn: 1753 init1: 1753 opt: 1753  Z-score: 2181.7  bits: 411.3 E(85289): 8.8e-115
Smith-Waterman score: 1753; 100.0% identity (100.0% similar) in 258 aa overlap (1-258:1-258)

               10        20        30        40        50        60
pF1KB6 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 AAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 YWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTV
              190       200       210       220       230       240

              250        
pF1KB6 FTQVSAYISWINNVIASN
       ::::::::::::::::::
NP_001 FTQVSAYISWINNVIASN
              250        

>>NP_254275 (OMIM: 609443) chymotrypsin-like elastase fa  (269 aa)
 initn: 978 init1: 820 opt: 997  Z-score: 1242.9  bits: 237.6 E(85289): 1.7e-62
Smith-Waterman score: 997; 57.5% identity (80.6% similar) in 247 aa overlap (13-258:23-269)

                         10        20        30        40        50
pF1KB6           MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGG
                             :   .::::: ::  :::: :.:::: :.:. ::::::
NP_254 MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGG
               10        20        30        40        50        60

               60        70        80        90       100       110
pF1KB6 TLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGY
       .:: ..::.:::::.. ..:.::  : :::   ..    :::.:::::  :::.... : 
NP_254 SLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGN
               70        80        90       100       110       120

              120       130       140       150       160       170
pF1KB6 DIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPS
       :::::.::. :.:.. .::. ::  :.:: :: :::.::::. .::: . ..:::. :  
NP_254 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLV
              130       140       150       160       170       180

              180       190       200       210        220         
pF1KB6 VDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLV-NGKYSVHGVTSFVSS
       :::: ::::..:::.::..:.::::::: :.:.:::::::.: . .:...:::..:: : 
NP_254 VDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSR
              190       200       210       220       230       240

     230       240       250        
pF1KB6 RGCNVSRKPTVFTQVSAYISWINNVIASN
        :::  .::.:::.:: ::.:::.:::.:
NP_254 LGCNYYHKPSVFTRVSNYIDWINSVIANN
              250       260         

>>NP_056933 (OMIM: 609444) chymotrypsin-like elastase fa  (269 aa)
 initn: 938 init1: 796 opt: 962  Z-score: 1199.4  bits: 229.6 E(85289): 4.5e-60
Smith-Waterman score: 962; 56.4% identity (79.0% similar) in 243 aa overlap (17-258:27-269)

                         10        20        30        40        50
pF1KB6           MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGG
                                 .:..:: ::  :::: :.:::: :.:. ::::::
NP_056 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG
               10        20        30        40        50        60

               60        70        80        90       100       110
pF1KB6 TLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGY
       .:: ..::.:::::.. .  .::. :.:::   ..    :::.:::::  ::::.:. : 
NP_056 SLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN
               70        80        90       100       110       120

              120       130       140       150       160       170
pF1KB6 DIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPS
       :::::.::. :.:.. .::. ::  :.:: :: :::.::::. .::: : . :.:. :  
NP_056 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLV
              130       140       150       160       170       180

              180       190       200       210        220         
pF1KB6 VDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLV-NGKYSVHGVTSFVSS
       :::: ::::..::::::..:.:::::::   :.:::::::.: . .:.. :::. :..: 
NP_056 VDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSV
              190       200       210       220       230       240

     230       240       250        
pF1KB6 RGCNVSRKPTVFTQVSAYISWINNVIASN
        :::   ::..::.:: : .:::.:::.:
NP_056 LGCNYYYKPSIFTRVSNYNDWINSVIANN
              250       260         

>>NP_009203 (OMIM: 167800,601405) chymotrypsin-C preprop  (268 aa)
 initn: 418 init1: 418 opt: 852  Z-score: 1062.9  bits: 204.3 E(85289): 1.8e-52
Smith-Waterman score: 852; 52.3% identity (77.0% similar) in 243 aa overlap (13-252:24-263)

                          10        20        30        40         
pF1KB6            MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCG
                              :. .:::::: .:  .::: :::::: .. .  ::::
NP_009 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
               10        20        30        40        50        60

      50        60        70        80          90       100       
pF1KB6 GTLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQND--GTEQYVSVQKIVVHPYWNSDNVA
       :::: .:.:.:::::..  .:.::..: .::  .:  :.  .:.:. : ::  ::.  . 
NP_009 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGS-LFVGVDTIHVHKRWNA--LL
               70        80        90        100       110         

       110       120       130       140       150       160       
pF1KB6 AGYDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAY
          ::::..::. : :.. .:.. ::.. ..: .. :::.::::.  ::: .:. :::. 
NP_009 LRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGL
       120       130       140       150       160       170       

       170       180       190       200       210        220      
pF1KB6 LPSVDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHC-LVNGKYSVHGVTSF
        : ::.: ::  ..::  ::.:::::::::: :.:.:::::::.: : ::.. : :..::
NP_009 QPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSF
       180       190       200       210       220       230       

        230       240       250        
pF1KB6 VSSRGCNVSRKPTVFTQVSAYISWINNVIASN
        : ::::. .::.:.:.:::::.:::      
NP_009 GSRRGCNTRKKPVVYTRVSAYIDWINEKMQL 
       240       250       260         

>>NP_001898 (OMIM: 118888) chymotrypsin-like protease CT  (264 aa)
 initn: 484 init1: 194 opt: 617  Z-score: 771.2  bits: 150.3 E(85289): 3.2e-36
Smith-Waterman score: 617; 41.6% identity (69.5% similar) in 243 aa overlap (18-258:33-264)

                            10        20        30        40       
pF1KB6              MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHT
                                     :.:.: .:  .::: :.:::  ::   .: 
NP_001 LLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSG---FHF
             10        20        30        40        50            

        50        60         70        80        90       100      
pF1KB6 CGGTLIRQNWVMTAAHC-VDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNV
       :::.:: :.::.::::: :.  . : :: :... :.:    : .::.. ..:: ::: ..
NP_001 CGGSLISQSWVVTAAHCNVSPGRHF-VVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTM
      60        70        80         90       100       110        

        110       120       130       140       150       160      
pF1KB6 AAGYDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQT-LQQ
           :..::.::. .  .. ..   : . .  :...  :  ::::. .  :... . :::
NP_001 NN--DVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQ
      120         130       140       150       160       170      

         170       180       190       200       210       220     
pF1KB6 AYLPSVDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTS
       . :: :    : .  ::::.. ..:.:::: :. :.::::::::: :  .. . . :..:
NP_001 VALPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGNTWVLIGIVS
        180         190       200        210       220       230   

         230       240       250        
pF1KB6 FVSSRGCNVSRKPTVFTQVSAYISWINNVIASN
       . ....::: : :.:.:.:: . .:::.::: :
NP_001 W-GTKNCNV-RAPAVYTRVSKFSTWINQVIAYN
            240        250       260    

>>NP_001897 (OMIM: 118890) chymotrypsinogen B isoform 1   (263 aa)
 initn: 405 init1: 115 opt: 552  Z-score: 690.6  bits: 135.4 E(85289): 1e-31
Smith-Waterman score: 552; 37.4% identity (69.5% similar) in 243 aa overlap (17-258:32-263)

                             10        20        30        40      
pF1KB6               MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYH
                                     .:.:.: .:  .::: :.::: ..:   .:
NP_001 ASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTG---FH
              10        20        30        40        50           

         50        60        70        80        90       100      
pF1KB6 TCGGTLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNV
        :::.:: ..::.:::::   . .  ::::. . .... . : ... :.  .: ..  .:
NP_001 FCGGSLISEDWVVTAAHC-GVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTV
       60        70         80        90       100       110       

        110       120       130       140       150        160     
pF1KB6 AAGYDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNG-QLAQTLQQ
         . ::.::.::  . ... :.   ::.    .  .. :  ::::::: :. .  . :::
NP_001 --NNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQ
         120       130       140       150       160       170     

         170       180       190       200       210       220     
pF1KB6 AYLPSVDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTS
       : :: .. : :..:  ::  . ..:.:::..:: :.:.::::::: :  .: ... :..:
NP_001 AALPLLSNAECKKS--WGRRITDVMICAGASGV-SSCMGDSGGPLVCQKDGAWTLVGIVS
         180         190       200        210       220       230  

         230       240       250        
pF1KB6 FVSSRGCNVSRKPTVFTQVSAYISWINNVIASN
       . .:  :..: .: :...:.  : :.....:.:
NP_001 W-GSDTCSTS-SPGVYARVTKLIPWVQKILAAN
             240        250       260   

>>XP_016863673 (OMIM: 229000,612423) PREDICTED: plasma k  (436 aa)
 initn: 435 init1: 269 opt: 553  Z-score: 688.8  bits: 135.8 E(85289): 1.3e-31
Smith-Waterman score: 553; 35.1% identity (65.7% similar) in 251 aa overlap (6-251:176-419)

                                        10        20        30     
pF1KB6                          MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQIS
                                     : ..    .:..:.::::... . :: :.:
XP_016 FLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVS
         150       160       170       180       190       200     

          40        50        60           70        80        90  
pF1KB6 LQYRSGGSRYHTCGGTLIRQNWVMTAAHCVD---YQKTFRVVAGDHNLSQNDGTEQYVSV
       :: .  ..: : :::.:: ..::.::::: :    : ..:. .:  :::.      . ..
XP_016 LQVKLTAQR-HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQI
         210        220       230       240       250       260    

            100        110       120       130       140       150 
pF1KB6 QKIVVHPYWNSDNVAAG-YDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWG
       ..:..:  .   .:. : .::::..:   .. . . .   ::..:   .  . :..::::
XP_016 KEIIIHQNY---KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWG
          270          280       290       300       310       320 

             160       170       180       190        200       210
pF1KB6 KTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAG-GDGVRSGCQGDSGGPL
        .: .:.. . ::.. .: :    :..  :    . . :::::  .: ...:.:::::::
XP_016 FSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGYKEGGKDACKGDSGGPL
             330       340        350       360       370       380

              220       230       240       250                  
pF1KB6 HCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIASN          
        :  :: . . :.::.  ..::   ..: :.:.:. :..::                 
XP_016 VCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
              390         400       410       420       430      

>>NP_001305325 (OMIM: 229000,612423) plasma kallikrein i  (436 aa)
 initn: 435 init1: 269 opt: 553  Z-score: 688.8  bits: 135.8 E(85289): 1.3e-31
Smith-Waterman score: 553; 35.1% identity (65.7% similar) in 251 aa overlap (6-251:176-419)

                                        10        20        30     
pF1KB6                          MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQIS
                                     : ..    .:..:.::::... . :: :.:
NP_001 FLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVS
         150       160       170       180       190       200     

          40        50        60           70        80        90  
pF1KB6 LQYRSGGSRYHTCGGTLIRQNWVMTAAHCVD---YQKTFRVVAGDHNLSQNDGTEQYVSV
       :: .  ..: : :::.:: ..::.::::: :    : ..:. .:  :::.      . ..
NP_001 LQVKLTAQR-HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQI
         210        220       230       240       250       260    

            100        110       120       130       140       150 
pF1KB6 QKIVVHPYWNSDNVAAG-YDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWG
       ..:..:  .   .:. : .::::..:   .. . . .   ::..:   .  . :..::::
NP_001 KEIIIHQNY---KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWG
          270          280       290       300       310       320 

             160       170       180       190        200       210
pF1KB6 KTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAG-GDGVRSGCQGDSGGPL
        .: .:.. . ::.. .: :    :..  :    . . :::::  .: ...:.:::::::
NP_001 FSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGYKEGGKDACKGDSGGPL
             330       340        350       360       370       380

              220       230       240       250                  
pF1KB6 HCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIASN          
        :  :: . . :.::.  ..::   ..: :.:.:. :..::                 
NP_001 VCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
              390         400       410       420       430      

>>NP_000883 (OMIM: 229000,612423) plasma kallikrein isof  (638 aa)
 initn: 435 init1: 269 opt: 553  Z-score: 686.5  bits: 135.9 E(85289): 1.7e-31
Smith-Waterman score: 553; 35.1% identity (65.7% similar) in 251 aa overlap (6-251:378-621)

                                        10        20        30     
pF1KB6                          MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQIS
                                     : ..    .:..:.::::... . :: :.:
NP_000 FLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVS
       350       360       370       380       390       400       

          40        50        60           70        80        90  
pF1KB6 LQYRSGGSRYHTCGGTLIRQNWVMTAAHCVD---YQKTFRVVAGDHNLSQNDGTEQYVSV
       :: .  ..: : :::.:: ..::.::::: :    : ..:. .:  :::.      . ..
NP_000 LQVKLTAQR-HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQI
       410        420       430       440       450       460      

            100        110       120       130       140       150 
pF1KB6 QKIVVHPYWNSDNVAAG-YDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWG
       ..:..:  .   .:. : .::::..:   .. . . .   ::..:   .  . :..::::
NP_000 KEIIIHQNY---KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWG
        470          480       490       500       510       520   

             160       170       180       190        200       210
pF1KB6 KTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAG-GDGVRSGCQGDSGGPL
        .: .:.. . ::.. .: :    :..  :    . . :::::  .: ...:.:::::::
NP_000 FSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGYKEGGKDACKGDSGGPL
           530       540       550        560       570       580  

              220       230       240       250                  
pF1KB6 HCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIASN          
        :  :: . . :.::.  ..::   ..: :.:.:. :..::                 
NP_000 VCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
            590         600       610       620       630        

>>XP_011530232 (OMIM: 229000,612423) PREDICTED: plasma k  (649 aa)
 initn: 435 init1: 269 opt: 553  Z-score: 686.4  bits: 135.9 E(85289): 1.7e-31
Smith-Waterman score: 553; 35.1% identity (65.7% similar) in 251 aa overlap (6-251:389-632)

                                        10        20        30     
pF1KB6                          MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQIS
                                     : ..    .:..:.::::... . :: :.:
XP_011 FLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVS
      360       370       380       390       400       410        

          40        50        60           70        80        90  
pF1KB6 LQYRSGGSRYHTCGGTLIRQNWVMTAAHCVD---YQKTFRVVAGDHNLSQNDGTEQYVSV
       :: .  ..: : :::.:: ..::.::::: :    : ..:. .:  :::.      . ..
XP_011 LQVKLTAQR-HLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQI
      420        430       440       450       460       470       

            100        110       120       130       140       150 
pF1KB6 QKIVVHPYWNSDNVAAG-YDIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWG
       ..:..:  .   .:. : .::::..:   .. . . .   ::..:   .  . :..::::
XP_011 KEIIIHQNY---KVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWG
       480          490       500       510       520       530    

             160       170       180       190        200       210
pF1KB6 KTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAG-GDGVRSGCQGDSGGPL
        .: .:.. . ::.. .: :    :..  :    . . :::::  .: ...:.:::::::
XP_011 FSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAGYKEGGKDACKGDSGGPL
          540       550       560        570       580       590   

              220       230       240       250                  
pF1KB6 HCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIASN          
        :  :: . . :.::.  ..::   ..: :.:.:. :..::                 
XP_011 VCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
           600         610       620       630       640         




258 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:28:50 2016 done: Fri Nov  4 20:28:51 2016
 Total Scan time:  5.720 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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