Result of FASTA (omim) for pF1KB6402
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6402, 333 aa
  1>>>pF1KB6402 333 - 333 aa - 333 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4930+/-0.000399; mu= 14.6756+/- 0.025
 mean_var=67.1104+/-13.494, 0's: 0 Z-trim(111.9): 59  B-trim: 44 in 1/49
 Lambda= 0.156559
 statistics sampled from 20570 (20630) to 20570 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.242), width:  16
 Scan time:  7.220

The best scores are:                                      opt bits E(85289)
NP_001903 (OMIM: 116880) cathepsin L1 isoform 1 pr ( 333) 2321 533.4 2.6e-151
XP_005251773 (OMIM: 116880) PREDICTED: cathepsin L ( 333) 2321 533.4 2.6e-151
NP_001244900 (OMIM: 116880) cathepsin L1 isoform 1 ( 333) 2321 533.4 2.6e-151
NP_666023 (OMIM: 116880) cathepsin L1 isoform 1 pr ( 333) 2321 533.4 2.6e-151
NP_001244901 (OMIM: 116880) cathepsin L1 isoform 1 ( 333) 2321 533.4 2.6e-151
NP_001324 (OMIM: 603308) cathepsin L2 preproprotei ( 334) 1836 423.8 2.5e-118
NP_001188504 (OMIM: 603308) cathepsin L2 prepropro ( 334) 1836 423.8 2.5e-118
XP_016869782 (OMIM: 116880) PREDICTED: cathepsin L ( 272) 1804 416.5 3.1e-116
XP_011516565 (OMIM: 116880) PREDICTED: cathepsin L ( 272) 1804 416.5 3.1e-116
NP_000387 (OMIM: 265800,601105) cathepsin K prepro ( 329) 1131 264.6 2.1e-70
NP_004070 (OMIM: 116845) cathepsin S isoform 1 pre ( 331) 1101 257.8 2.3e-68
NP_001244902 (OMIM: 116880) cathepsin L1 isoform 2 ( 151) 1041 244.1 1.4e-64
NP_001186668 (OMIM: 116845) cathepsin S isoform 2  ( 281)  796 188.9 1.1e-47
NP_004381 (OMIM: 116820) pro-cathepsin H isoform a ( 335)  796 188.9 1.3e-47
XP_016877440 (OMIM: 116820) PREDICTED: pro-catheps ( 317)  770 183.0 7.2e-46
XP_016877441 (OMIM: 116820) PREDICTED: pro-catheps ( 297)  767 182.3 1.1e-45
XP_005254238 (OMIM: 116820) PREDICTED: pro-catheps ( 297)  767 182.3 1.1e-45
XP_011543630 (OMIM: 603539,615362) PREDICTED: cath ( 424)  664 159.1 1.5e-38
NP_003784 (OMIM: 603539,615362) cathepsin F precur ( 484)  664 159.2 1.7e-38
NP_001325 (OMIM: 600550) cathepsin O preproprotein ( 321)  484 118.4   2e-26
NP_001306066 (OMIM: 116820) pro-cathepsin H isofor ( 201)  459 112.7 6.8e-25
NP_001326 (OMIM: 602364) cathepsin W preproprotein ( 376)  403 100.2 7.5e-21
NP_001805 (OMIM: 170650,245000,245010,602365) dipe ( 463)  386 96.4 1.3e-19
XP_011519578 (OMIM: 116820) PREDICTED: pro-catheps ( 169)  338 85.3 9.9e-17
NP_001327 (OMIM: 603169) cathepsin Z preproprotein ( 303)  305 78.0 2.9e-14
NP_001304166 (OMIM: 116810) cathepsin B isoform 2  ( 215)  223 59.4   8e-09
XP_016868590 (OMIM: 116810) PREDICTED: cathepsin B ( 245)  223 59.4   9e-09
XP_006716307 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  223 59.5 1.2e-08
XP_016868586 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  223 59.5 1.2e-08
NP_680092 (OMIM: 116810) cathepsin B isoform 1 pre ( 339)  223 59.5 1.2e-08
XP_006716308 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  223 59.5 1.2e-08
NP_001899 (OMIM: 116810) cathepsin B isoform 1 pre ( 339)  223 59.5 1.2e-08
XP_016868588 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  223 59.5 1.2e-08
NP_680091 (OMIM: 116810) cathepsin B isoform 1 pre ( 339)  223 59.5 1.2e-08
XP_016868589 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  223 59.5 1.2e-08
NP_680093 (OMIM: 116810) cathepsin B isoform 1 pre ( 339)  223 59.5 1.2e-08
XP_011542114 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  223 59.5 1.2e-08
NP_680090 (OMIM: 116810) cathepsin B isoform 1 pre ( 339)  223 59.5 1.2e-08
XP_016868587 (OMIM: 116810) PREDICTED: cathepsin B ( 339)  223 59.5 1.2e-08
XP_005271164 (OMIM: 616064) PREDICTED: tubulointer ( 362)  196 53.4 8.6e-07
NP_001191344 (OMIM: 616064) tubulointerstitial nep ( 362)  196 53.4 8.6e-07
XP_011540248 (OMIM: 616064) PREDICTED: tubulointer ( 408)  196 53.4 9.6e-07
NP_001191343 (OMIM: 616064) tubulointerstitial nep ( 436)  196 53.4   1e-06
NP_071447 (OMIM: 616064) tubulointerstitial nephri ( 467)  196 53.5 1.1e-06
XP_016866237 (OMIM: 606749) PREDICTED: tubulointer ( 309)  178 49.3 1.3e-05
XP_016866236 (OMIM: 606749) PREDICTED: tubulointer ( 351)  178 49.3 1.4e-05
XP_016866235 (OMIM: 606749) PREDICTED: tubulointer ( 401)  178 49.4 1.6e-05
XP_011512799 (OMIM: 606749) PREDICTED: tubulointer ( 426)  178 49.4 1.7e-05
XP_006715125 (OMIM: 606749) PREDICTED: tubulointer ( 458)  178 49.4 1.8e-05
NP_055279 (OMIM: 606749) tubulointerstitial nephri ( 476)  178 49.4 1.8e-05


>>NP_001903 (OMIM: 116880) cathepsin L1 isoform 1 prepro  (333 aa)
 initn: 2321 init1: 2321 opt: 2321  Z-score: 2837.4  bits: 533.4 E(85289): 2.6e-151
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333)

               10        20        30        40        50        60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
              250       260       270       280       290       300

              310       320       330   
pF1KB6 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
       :::::::::::::::::::::::::::::::::
NP_001 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
              310       320       330   

>>XP_005251773 (OMIM: 116880) PREDICTED: cathepsin L1 is  (333 aa)
 initn: 2321 init1: 2321 opt: 2321  Z-score: 2837.4  bits: 533.4 E(85289): 2.6e-151
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333)

               10        20        30        40        50        60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
              250       260       270       280       290       300

              310       320       330   
pF1KB6 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
       :::::::::::::::::::::::::::::::::
XP_005 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
              310       320       330   

>>NP_001244900 (OMIM: 116880) cathepsin L1 isoform 1 pre  (333 aa)
 initn: 2321 init1: 2321 opt: 2321  Z-score: 2837.4  bits: 533.4 E(85289): 2.6e-151
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333)

               10        20        30        40        50        60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
              250       260       270       280       290       300

              310       320       330   
pF1KB6 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
       :::::::::::::::::::::::::::::::::
NP_001 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
              310       320       330   

>>NP_666023 (OMIM: 116880) cathepsin L1 isoform 1 prepro  (333 aa)
 initn: 2321 init1: 2321 opt: 2321  Z-score: 2837.4  bits: 533.4 E(85289): 2.6e-151
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333)

               10        20        30        40        50        60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_666 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_666 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_666 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_666 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_666 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
              250       260       270       280       290       300

              310       320       330   
pF1KB6 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
       :::::::::::::::::::::::::::::::::
NP_666 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
              310       320       330   

>>NP_001244901 (OMIM: 116880) cathepsin L1 isoform 1 pre  (333 aa)
 initn: 2321 init1: 2321 opt: 2321  Z-score: 2837.4  bits: 533.4 E(85289): 2.6e-151
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333)

               10        20        30        40        50        60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
              250       260       270       280       290       300

              310       320       330   
pF1KB6 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
       :::::::::::::::::::::::::::::::::
NP_001 SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
              310       320       330   

>>NP_001324 (OMIM: 603308) cathepsin L2 preproprotein [H  (334 aa)
 initn: 1824 init1: 1251 opt: 1836  Z-score: 2245.4  bits: 423.8 E(85289): 2.5e-118
Smith-Waterman score: 1836; 77.2% identity (91.0% similar) in 334 aa overlap (1-333:1-334)

               10        20        30        40        50        60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
       :: .:.:::::::::::.  ::..:...: .::: : :::: ::::::::::::::::::
NP_001 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
       ::: :: .:::.::::::::::::.:::::.:. :.:.: ::::::.:::: . :.::::
NP_001 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
       :.:::::::::: :::::::::::::::::::::::.:.::::::::::: ::::.::::
NP_001 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
              130       140       150       160       170       180

              190       200       210       220        230         
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQEKALMKAV
       :.:  :::::..:::::::::::: :..: ::: :. ::::::::. . : .::::::::
NP_001 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB6 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK
       :::::::::.:::: :: ::: ::::::::::...::::::::::::...:.:.::::::
NP_001 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
              250       260       270       280       290       300

     300       310       320       330   
pF1KB6 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
       :::: ::: .::::.:::. ::::::.:::::.:
NP_001 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
              310       320       330    

>>NP_001188504 (OMIM: 603308) cathepsin L2 preproprotein  (334 aa)
 initn: 1824 init1: 1251 opt: 1836  Z-score: 2245.4  bits: 423.8 E(85289): 2.5e-118
Smith-Waterman score: 1836; 77.2% identity (91.0% similar) in 334 aa overlap (1-333:1-334)

               10        20        30        40        50        60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
       :: .:.:::::::::::.  ::..:...: .::: : :::: ::::::::::::::::::
NP_001 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
       ::: :: .:::.::::::::::::.:::::.:. :.:.: ::::::.:::: . :.::::
NP_001 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
       :.:::::::::: :::::::::::::::::::::::.:.::::::::::: ::::.::::
NP_001 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
              130       140       150       160       170       180

              190       200       210       220        230         
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQEKALMKAV
       :.:  :::::..:::::::::::: :..: ::: :. ::::::::. . : .::::::::
NP_001 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KB6 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK
       :::::::::.:::: :: ::: ::::::::::...::::::::::::...:.:.::::::
NP_001 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
              250       260       270       280       290       300

     300       310       320       330   
pF1KB6 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
       :::: ::: .::::.:::. ::::::.:::::.:
NP_001 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
              310       320       330    

>>XP_016869782 (OMIM: 116880) PREDICTED: cathepsin L1 is  (272 aa)
 initn: 1804 init1: 1804 opt: 1804  Z-score: 2207.7  bits: 416.5 E(85289): 3.1e-116
Smith-Waterman score: 1804; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)

               10        20        30        40        50        60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
       :::::::::::::::::::::                                       
XP_016 TVGPISVAIDAGHESFLFYKEAGVKNGAWVAT                            
              250       260       270                              

>>XP_011516565 (OMIM: 116880) PREDICTED: cathepsin L1 is  (272 aa)
 initn: 1804 init1: 1804 opt: 1804  Z-score: 2207.7  bits: 416.5 E(85289): 3.1e-116
Smith-Waterman score: 1804; 100.0% identity (100.0% similar) in 261 aa overlap (1-261:1-261)

               10        20        30        40        50        60
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
       :::::::::::::::::::::                                       
XP_011 TVGPISVAIDAGHESFLFYKEAGVKNGAWVAT                            
              250       260       270                              

>>NP_000387 (OMIM: 265800,601105) cathepsin K preproprot  (329 aa)
 initn: 887 init1: 321 opt: 1131  Z-score: 1384.9  bits: 264.6 E(85289): 2.1e-70
Smith-Waterman score: 1131; 50.9% identity (76.7% similar) in 330 aa overlap (7-331:4-327)

               10        20        30        40         50         
pF1KB6 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMI
             : .. : ..: .:  .. :...:  ::  : . :. . .:  :: .::::.:.:
NP_000    MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYI
                  10        20        30        40        50       

      60        70        80        90         100       110       
pF1KB6 ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQN--RKPRKGKVFQEPLFY-EAPR
        .:: :   : :.. .::: .:::::::  : :.:..    . :.. ..  : .  .:: 
NP_000 SIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPD
        60        70        80        90       100       110       

        120       130       140       150       160       170      
pF1KB6 SVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE
       :::.:.::::::::::::::::::::..::::::. .:::.:..:: :::::: .   :.
NP_000 SVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--ND
       120       130       140       150       160       170       

        180       190       200       210       220       230      
pF1KB6 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKAL
       ::.:: :  :::::: : :.:::..::: . :::: :::  ..:.  :. .::. .::::
NP_000 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL
         180       190       200       210       220       230     

         240       250       260       270       280       290     
pF1KB6 MKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKY
        .::: :::.::::::.  :: ::..:.:.. .:.:....:.::.::::...    .::.
NP_000 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK----GNKH
         240       250       260       270       280           290 

         300       310       320       330   
pF1KB6 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
       :..::::::.::  ::. ::... : ::::. ::.:  
NP_000 WIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
             300       310       320         




333 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:49:15 2016 done: Fri Nov  4 20:49:16 2016
 Total Scan time:  7.220 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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