Result of FASTA (omim) for pF1KE0430
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0430, 417 aa
  1>>>pF1KE0430 417 - 417 aa - 417 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.0370+/-0.000328; mu= 7.8540+/- 0.020
 mean_var=262.9647+/-54.171, 0's: 0 Z-trim(123.6): 253  B-trim: 0 in 0/55
 Lambda= 0.079091
 statistics sampled from 43448 (43790) to 43448 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.806), E-opt: 0.2 (0.513), width:  16
 Scan time:  9.910

The best scores are:                                      opt bits E(85289)
NP_056328 (OMIM: 606217,607170) cysteine-rich with ( 420) 3077 363.9 4.3e-100
NP_001070883 (OMIM: 606217,607170) cysteine-rich w ( 420) 3077 363.9 4.3e-100
XP_016862664 (OMIM: 606217,607170) PREDICTED: cyst ( 420) 3073 363.4 5.9e-100
NP_001026887 (OMIM: 606217,607170) cysteine-rich w ( 422) 2654 315.6 1.5e-85
XP_011532410 (OMIM: 606217,607170) PREDICTED: cyst ( 426) 2652 315.4 1.7e-85
XP_005261795 (OMIM: 607171) PREDICTED: cysteine-ri ( 373) 1303 161.4 3.5e-39
NP_077300 (OMIM: 607171) cysteine-rich with EGF-li ( 353) 1299 160.9 4.6e-39
NP_001271247 (OMIM: 607171) cysteine-rich with EGF ( 321) 1057 133.2 8.9e-31
NP_001271246 (OMIM: 607171) cysteine-rich with EGF ( 325)  953 121.4 3.3e-27
XP_016884427 (OMIM: 607171) PREDICTED: cysteine-ri ( 252)  895 114.6 2.8e-25
NP_001128573 (OMIM: 607171) cysteine-rich with EGF ( 402)  819 106.2 1.5e-22
XP_005261794 (OMIM: 607171) PREDICTED: cysteine-ri ( 403)  819 106.2 1.5e-22
XP_011528674 (OMIM: 607171) PREDICTED: cysteine-ri ( 208)  809 104.7 2.2e-22
XP_006713128 (OMIM: 608560) PREDICTED: stabilin-1  (1619)  323 50.3   4e-05
XP_016861493 (OMIM: 608560) PREDICTED: stabilin-1  (1819)  323 50.4 4.3e-05
XP_016861492 (OMIM: 608560) PREDICTED: stabilin-1  (2555)  323 50.6 5.4e-05
XP_016861491 (OMIM: 608560) PREDICTED: stabilin-1  (2565)  323 50.6 5.4e-05
XP_005265031 (OMIM: 608560) PREDICTED: stabilin-1  (2569)  323 50.6 5.4e-05
NP_055951 (OMIM: 608560) stabilin-1 precursor [Hom (2570)  323 50.6 5.4e-05
XP_016861490 (OMIM: 608560) PREDICTED: stabilin-1  (2583)  323 50.6 5.4e-05
XP_016861489 (OMIM: 608560) PREDICTED: stabilin-1  (2589)  323 50.6 5.4e-05
XP_016861488 (OMIM: 608560) PREDICTED: stabilin-1  (2590)  323 50.6 5.4e-05
XP_005265030 (OMIM: 608560) PREDICTED: stabilin-1  (2595)  323 50.6 5.4e-05
XP_016861487 (OMIM: 608560) PREDICTED: stabilin-1  (2615)  323 50.6 5.5e-05
XP_011536844 (OMIM: 608561) PREDICTED: stabilin-2  (1238)  295 47.0 0.00031
XP_011536843 (OMIM: 608561) PREDICTED: stabilin-2  (1684)  295 47.2 0.00038
XP_011536841 (OMIM: 608561) PREDICTED: stabilin-2  (1994)  295 47.3 0.00042
XP_011536840 (OMIM: 608561) PREDICTED: stabilin-2  (2242)  295 47.3 0.00045
XP_016875074 (OMIM: 608561) PREDICTED: stabilin-2  (2246)  295 47.3 0.00045
XP_011536839 (OMIM: 608561) PREDICTED: stabilin-2  (2283)  295 47.3 0.00046
NP_060034 (OMIM: 608561) stabilin-2 precursor [Hom (2551)  295 47.4 0.00049
NP_001159605 (OMIM: 219000,607830) extracellular m (1976)  286 46.2 0.00085
XP_011525689 (OMIM: 604710,613177) PREDICTED: late (1421)  282 45.6 0.00095
XP_011525688 (OMIM: 604710,613177) PREDICTED: late (1436)  282 45.6 0.00096
XP_016882843 (OMIM: 604710,613177) PREDICTED: late (1438)  282 45.6 0.00096
XP_011525687 (OMIM: 604710,613177) PREDICTED: late (1478)  282 45.6 0.00097
XP_011525686 (OMIM: 604710,613177) PREDICTED: late (1480)  282 45.6 0.00098
XP_011525685 (OMIM: 604710,613177) PREDICTED: late (1522)  282 45.6 0.00099
XP_016882842 (OMIM: 604710,613177) PREDICTED: late (1549)  282 45.6   0.001
NP_001036010 (OMIM: 604710,613177) latent-transfor (1557)  282 45.6   0.001
NP_003564 (OMIM: 604710,613177) latent-transformin (1587)  282 45.7   0.001
XP_016882841 (OMIM: 604710,613177) PREDICTED: late (1591)  282 45.7   0.001
XP_011525682 (OMIM: 604710,613177) PREDICTED: late (1593)  282 45.7   0.001
XP_011525683 (OMIM: 604710,613177) PREDICTED: late (1593)  282 45.7   0.001
XP_011525681 (OMIM: 604710,613177) PREDICTED: late (1595)  282 45.7   0.001
XP_011525680 (OMIM: 604710,613177) PREDICTED: late (1611)  282 45.7   0.001
NP_001036009 (OMIM: 604710,613177) latent-transfor (1624)  282 45.7   0.001
XP_011525679 (OMIM: 604710,613177) PREDICTED: late (1635)  282 45.7   0.001
XP_011525678 (OMIM: 604710,613177) PREDICTED: late (1662)  282 45.7  0.0011
XP_006714379 (OMIM: 219000,607830) PREDICTED: extr (3936)  286 46.6  0.0013


>>NP_056328 (OMIM: 606217,607170) cysteine-rich with EGF  (420 aa)
 initn: 3077 init1: 3077 opt: 3077  Z-score: 1917.9  bits: 363.9 E(85289): 4.3e-100
Smith-Waterman score: 3077; 99.5% identity (99.5% similar) in 417 aa overlap (1-417:1-417)

               10        20        30        40        50        60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
       ::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE
       ::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_056 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE
              310       320       330       340       350       360

              370       380       390       400       410          
pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI   
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_056 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
              370       380       390       400       410       420

>>NP_001070883 (OMIM: 606217,607170) cysteine-rich with   (420 aa)
 initn: 3077 init1: 3077 opt: 3077  Z-score: 1917.9  bits: 363.9 E(85289): 4.3e-100
Smith-Waterman score: 3077; 99.5% identity (99.5% similar) in 417 aa overlap (1-417:1-417)

               10        20        30        40        50        60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
       ::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE
       ::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE
              310       320       330       340       350       360

              370       380       390       400       410          
pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI   
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_001 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
              370       380       390       400       410       420

>>XP_016862664 (OMIM: 606217,607170) PREDICTED: cysteine  (420 aa)
 initn: 3073 init1: 3073 opt: 3073  Z-score: 1915.4  bits: 363.4 E(85289): 5.9e-100
Smith-Waterman score: 3073; 99.3% identity (99.5% similar) in 417 aa overlap (1-417:1-417)

               10        20        30        40        50        60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
       ::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
       ::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE
       ::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE
              310       320       330       340       350       360

              370       380       390       400       410          
pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI   
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_016 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
              370       380       390       400       410       420

>>NP_001026887 (OMIM: 606217,607170) cysteine-rich with   (422 aa)
 initn: 2647 init1: 2647 opt: 2654  Z-score: 1657.0  bits: 315.6 E(85289): 1.5e-85
Smith-Waterman score: 2654; 96.4% identity (98.3% similar) in 361 aa overlap (1-361:1-361)

               10        20        30        40        50        60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
       ::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEMTE
       ::::::::::::::::::::::::::::::::::: ::::::::::::: .  .....: 
NP_001 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPGAFPILTDLTP
              310       320       330       340       350       360

              370       380       390       400       410          
pF1KE0 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI   
       .                                                           
NP_001 ETTRRWKLGSHPHSTYVKMKMQRDEATFPGLYGKQVAKLGSQSRQSDRGTRLIHSQQASS
              370       380       390       400       410       420

>>XP_011532410 (OMIM: 606217,607170) PREDICTED: cysteine  (426 aa)
 initn: 2805 init1: 2646 opt: 2652  Z-score: 1655.8  bits: 315.4 E(85289): 1.7e-85
Smith-Waterman score: 2652; 96.7% identity (98.3% similar) in 361 aa overlap (1-360:1-361)

               10        20        30        40        50        60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
       ::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
       ::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
              250       260       270       280       290       300

              310       320       330       340       350          
pF1KE0 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESA-GFFSEMT
       ::::::::::::::::::::::::::::::::::: :::::::::::::... : :  .:
XP_011 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPDAVLGAFPILT
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KE0 EDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI  
       .                                                           
XP_011 DLTPETTRRWKLGSHPHSTYVKMKMQRDEATFPGLYGKQVAKLGSQSRQSDRGTRLIHSQ
              370       380       390       400       410       420

>>XP_005261795 (OMIM: 607171) PREDICTED: cysteine-rich w  (373 aa)
 initn: 1200 init1: 1200 opt: 1303  Z-score: 824.5  bits: 161.4 E(85289): 3.5e-39
Smith-Waterman score: 1303; 48.8% identity (72.1% similar) in 330 aa overlap (26-353:13-337)

               10        20        30        40        50        60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
                                :. :   : :...   .: ::: ::::::.::.:.
XP_005              MRLPRRAALGLLPLLLLLPPAPEAA--KKPTPCHRCRGLVDKFNQGM
                            10        20          30        40     

               70        80        90       100       110       120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
         : . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
XP_005 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
       .. ..  ::::.:.:  .::.::  ::.::.:: : ::..:::.: :.: :.:.: :.: 
XP_005 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
       : :. :: :  : .:  ::: . :: .: .:.::   :  :::  . .: .:. ::.: .
XP_005 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDE
         170       180       190       200       210       220     

              250       260       270       280       290       300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
         :::.:::..:   :.: ::: :..::: :..: ..:.:: : ::: ::.:  :: .  
XP_005 GACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREH
         230       240       250       260       270       280     

              310         320       330       340       350        
pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM
       ..: :::::    ..:  .:..: :: :.: :.: .: .. :  ::    :  ::     
XP_005 GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVP---PAEAGEWHGC
         290       300       310       320       330          340  

      360       370       380       390       400       410       
pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
                                                                  
XP_005 PPHRLPSPGPQGLHVDWLLGLKSTQMVALRW                            
            350       360       370                               

>>NP_077300 (OMIM: 607171) cysteine-rich with EGF-like d  (353 aa)
 initn: 1200 init1: 1200 opt: 1299  Z-score: 822.3  bits: 160.9 E(85289): 4.6e-39
Smith-Waterman score: 1299; 49.2% identity (73.2% similar) in 321 aa overlap (26-344:13-331)

               10        20        30        40        50        60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
                                :. :   : :...   .: ::: ::::::.::.:.
NP_077              MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM
                            10        20          30        40     

               70        80        90       100       110       120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
         : . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
NP_077 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
       .. ..  ::::.:.:  .::.::  ::.::.:: : ::..:::.: :.: :.:.: :.: 
NP_077 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
       : :. :: :  : .:  ::: . :: .: .:.::   :  :::  . .: .:. ::.: .
NP_077 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDE
         170       180       190       200       210       220     

              250       260       270       280       290       300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
         :::.:::..:   :.: ::: :..::: :..: ..:.:: : ::: ::.:  :: .  
NP_077 GACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREH
         230       240       250       260       270       280     

              310         320       330       340       350        
pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM
       ..: :::::    ..:  .:..: :: :.: :.: .: .. :  ::              
NP_077 GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT
         290       300       310       320       330       340     

      360       370       380       390       400       410       
pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
                                                                  
NP_077 QLPSREDL                                                   
         350                                                      

>>NP_001271247 (OMIM: 607171) cysteine-rich with EGF-lik  (321 aa)
 initn: 1093 init1: 1036 opt: 1057  Z-score: 673.6  bits: 133.2 E(85289): 8.9e-31
Smith-Waterman score: 1092; 44.9% identity (66.4% similar) in 321 aa overlap (26-344:13-299)

               10        20        30        40        50        60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
                                :. :   : :...   .: ::: ::::::.::.:.
NP_001              MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM
                            10        20          30        40     

               70        80        90       100       110       120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
         : . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
NP_001 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
       .. ..  ::::.:.:  .::.::  ::.::.:: : ::..:::.: :.: :.:.: :.: 
NP_001 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
       : :. :: :  : .:  ::: . :: .: .:.::   :  :::  . .: .:. ::.: .
NP_001 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDE
         170       180       190       200       210       220     

              250       260       270       280       290       300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
         :::.:::..:   :.: ::: :..::: :.                            
NP_001 GACVDVDECAAEPPPCSAAQFCKNANGSYTCE----------------------------
         230       240       250                                   

              310         320       330       340       350        
pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM
           :::::    ..:  .:..: :: :.: :.: .: .. :  ::              
NP_001 ----DVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT
           260       270       280       290       300       310   

      360       370       380       390       400       410       
pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
                                                                  
NP_001 QLPSREDL                                                   
           320                                                    

>>NP_001271246 (OMIM: 607171) cysteine-rich with EGF-lik  (325 aa)
 initn: 914 init1: 914 opt: 953  Z-score: 609.4  bits: 121.4 E(85289): 3.3e-27
Smith-Waterman score: 1118; 45.2% identity (66.7% similar) in 321 aa overlap (26-344:13-303)

               10        20        30        40        50        60
pF1KE0 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
                                :. :   : :...   .: ::: ::::::.::.:.
NP_001              MRLPRRAALGLLPLLLLLPPAPEAAK--KPTPCHRCRGLVDKFNQGM
                            10        20          30        40     

               70        80        90       100       110       120
pF1KE0 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
         : . :::::::::::..::::..:: ::.:.:::.: .:::::...:: .:: .:.::
NP_001 VDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEILEGLCESSDFECNQMLEAQEEHLEAWW
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KE0 FHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
       .. ..  ::::.:.:  .::.::  ::.::.:: : ::..:::.: :.: :.:.: :.: 
NP_001 LQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGS
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KE0 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
       : :. :: :  : .:  ::: . :: .: .:.::   :  :::  . .: .:. ::.:  
NP_001 CRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLD-
         170       180       190       200       210       220     

              250       260       270       280       290       300
pF1KE0 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
                  :::                : .: ..:.:: : ::: ::.:  :: .  
NP_001 -----------EGA----------------CVECDSSCVGCTGEGPGNCKECISGYAREH
                                     230       240       250       

              310         320       330       340       350        
pF1KE0 SKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGCKQMEGICVKEQIPESAGFFSEM
       ..: :::::    ..:  .:..: :: :.: :.: .: .. :  ::              
NP_001 GQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPT
       260       270       280       290       300       310       

      360       370       380       390       400       410       
pF1KE0 TEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFI
                                                                  
NP_001 QLPSREDL                                                   
       320                                                        

>>XP_016884427 (OMIM: 607171) PREDICTED: cysteine-rich w  (252 aa)
 initn: 798 init1: 798 opt: 895  Z-score: 574.9  bits: 114.6 E(85289): 2.8e-25
Smith-Waterman score: 895; 47.5% identity (70.3% similar) in 219 aa overlap (128-344:12-230)

       100       110       120       130       140       150       
pF1KE0 CSKSDFECHRLLELSEELVESWWFHKQQGAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPG
                                     ::::.:.:  .::.::  ::.::.:: : :
XP_016                    MFSSILRKSEYPDLFEWFCVKTLKVCCSPGTYGPDCLACQG
                                  10        20        30        40 

       160       170       180       190       200       210       
pF1KE0 GTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGP
       :..:::.: :.: :.:.: :.: : :. :: :  : .:  ::: . :: .: .:.::   
XP_016 GSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTACDES
              50        60        70        80        90       100 

       220       230       240       250       260       270       
pF1KE0 CARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKA
       :  :::  . .: .:. ::.: .  :::.:::..:   :.: ::: :..::: :..: ..
XP_016 CKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSS
             110       120       130       140       150       160 

       280       290       300       310         320       330     
pF1KE0 CLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECET--EVCPGENKQCENTEGGYRCICAEG
       :.:: : ::: ::.:  :: .  ..: :::::    ..:  .:..: :: :.: :.: .:
XP_016 CVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDG
             170       180       190       200       210       220 

         340       350       360       370       380       390     
pF1KE0 CKQMEGICVKEQIPESAGFFSEMTEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIG
        .. :  ::                                                   
XP_016 FEETEDACVPPAEAEATEGESPTQLPSREDL                             
             230       240       250                               




417 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 09:45:58 2016 done: Thu Nov  3 09:45:59 2016
 Total Scan time:  9.910 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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