Result of FASTA (omim) for pF1KE0114
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0114, 308 aa
  1>>>pF1KE0114 308 - 308 aa - 308 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1888+/-0.000314; mu= 16.1225+/- 0.020
 mean_var=66.6234+/-13.630, 0's: 0 Z-trim(116.6): 11  B-trim: 616 in 1/53
 Lambda= 0.157131
 statistics sampled from 27901 (27910) to 27901 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.327), width:  16
 Scan time:  7.830

The best scores are:                                      opt bits E(85289)
NP_009194 (OMIM: 606942) coatomer subunit epsilon  ( 308) 2016 465.6 5.6e-131
NP_955476 (OMIM: 606942) coatomer subunit epsilon  ( 256) 1242 290.1 3.2e-78
NP_955474 (OMIM: 606942) coatomer subunit epsilon  ( 257) 1050 246.6   4e-65
NP_001317398 (OMIM: 606942) coatomer subunit epsil ( 331) 1047 245.9   8e-65
XP_011525958 (OMIM: 606942) PREDICTED: coatomer su ( 279)  958 225.7 8.2e-59


>>NP_009194 (OMIM: 606942) coatomer subunit epsilon isof  (308 aa)
 initn: 2016 init1: 2016 opt: 2016  Z-score: 2472.4  bits: 465.6 E(85289): 5.6e-131
Smith-Waterman score: 2016; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308)

               10        20        30        40        50        60
pF1KE0 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
              250       260       270       280       290       300

               
pF1KE0 VLQYAPSA
       ::::::::
NP_009 VLQYAPSA
               

>>NP_955476 (OMIM: 606942) coatomer subunit epsilon isof  (256 aa)
 initn: 1242 init1: 1242 opt: 1242  Z-score: 1525.3  bits: 290.1 E(85289): 3.2e-78
Smith-Waterman score: 1547; 83.1% identity (83.1% similar) in 308 aa overlap (1-308:1-256)

               10        20        30        40        50        60
pF1KE0 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ
       :::::::::::::                                               
NP_955 LTQLATAWVSLAT-----------------------------------------------
              190                                                  

              250       260       270       280       290       300
pF1KE0 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
            :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 -----DSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
                200       210       220       230       240        

               
pF1KE0 VLQYAPSA
       ::::::::
NP_955 VLQYAPSA
      250      

>>NP_955474 (OMIM: 606942) coatomer subunit epsilon isof  (257 aa)
 initn: 1045 init1: 1045 opt: 1050  Z-score: 1290.1  bits: 246.6 E(85289): 4e-65
Smith-Waterman score: 1570; 83.1% identity (83.1% similar) in 308 aa overlap (1-308:1-257)

               10        20        30        40        50        60
pF1KE0 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
       ::::::::::::::::::::::::::::::::::::                        
NP_955 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRS-----------------------
               70        80        90                              

              130       140       150       160       170       180
pF1KE0 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT
                                   ::::::::::::::::::::::::::::::::
NP_955 ----------------------------TAMTVQILLKLDRLDLARKELKRMQDLDEDAT
                                   100       110       120         

              190       200       210       220       230       240
pF1KE0 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ
     130       140       150       160       170       180         

              250       260       270       280       290       300
pF1KE0 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
     190       200       210       220       230       240         

               
pF1KE0 VLQYAPSA
       ::::::::
NP_955 VLQYAPSA
     250       

>>NP_001317398 (OMIM: 606942) coatomer subunit epsilon i  (331 aa)
 initn: 1989 init1: 1045 opt: 1047  Z-score: 1284.8  bits: 245.9 E(85289): 8e-65
Smith-Waterman score: 1943; 92.7% identity (92.7% similar) in 331 aa overlap (1-308:1-331)

               10        20        30        40        50        60
pF1KE0 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
               70        80        90       100       110       120

              130       140                              150       
pF1KE0 LMAASIYLHDQNPDAALRALHQGDSLE-----------------------CTAMTVQILL
       :::::::::::::::::::::::::::                        :::::::::
NP_001 LMAASIYLHDQNPDAALRALHQGDSLEWVSSPGRALHLEAQPMEAASPDGRTAMTVQILL
              130       140       150       160       170       180

       160       170       180       190       200       210       
pF1KE0 KLDRLDLARKELKRMQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLDRLDLARKELKRMQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLL
              190       200       210       220       230       240

       220       230       240       250       260       270       
pF1KE0 LLNGQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLNGQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQL
              250       260       270       280       290       300

       280       290       300        
pF1KE0 KDAHRSHPFIKEYQAKENDFDRLVLQYAPSA
       :::::::::::::::::::::::::::::::
NP_001 KDAHRSHPFIKEYQAKENDFDRLVLQYAPSA
              310       320       330 

>>XP_011525958 (OMIM: 606942) PREDICTED: coatomer subuni  (279 aa)
 initn: 1366 init1: 958 opt: 958  Z-score: 1176.8  bits: 225.7 E(85289): 8.2e-59
Smith-Waterman score: 1474; 77.0% identity (77.0% similar) in 331 aa overlap (1-308:1-279)

               10        20        30        40        50        60
pF1KE0 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
               70        80        90       100       110       120

              130       140                              150       
pF1KE0 LMAASIYLHDQNPDAALRALHQGDSLE-----------------------CTAMTVQILL
       :::::::::::::::::::::::::::                        :::::::::
XP_011 LMAASIYLHDQNPDAALRALHQGDSLEWVSSPGRALHLEAQPMEAASPDGRTAMTVQILL
              130       140       150       160       170       180

       160       170       180       190       200       210       
pF1KE0 KLDRLDLARKELKRMQDLDEDATLTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLL
       ::::::::::::::::::::::::::::::::::::                        
XP_011 KLDRLDLARKELKRMQDLDEDATLTQLATAWVSLAT------------------------
              190       200       210                              

       220       230       240       250       260       270       
pF1KE0 LLNGQAACHMAQGRWEAAEGLLQEALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQL
                                   ::::::::::::::::::::::::::::::::
XP_011 ----------------------------DSGYPETLVNLIVLSQHLGKPPEVTNRYLSQL
                                    220       230       240        

       280       290       300        
pF1KE0 KDAHRSHPFIKEYQAKENDFDRLVLQYAPSA
       :::::::::::::::::::::::::::::::
XP_011 KDAHRSHPFIKEYQAKENDFDRLVLQYAPSA
      250       260       270         




308 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 02:31:23 2016 done: Fri Nov  4 02:31:24 2016
 Total Scan time:  7.830 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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