Result of FASTA (omim) for pF1KB8875
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8875, 166 aa
  1>>>pF1KB8875 166 - 166 aa - 166 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.7868+/-0.000508; mu= 4.4991+/- 0.031
 mean_var=199.1771+/-42.197, 0's: 0 Z-trim(114.7): 613  B-trim: 242 in 1/52
 Lambda= 0.090877
 statistics sampled from 23810 (24676) to 23810 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.289), width:  16
 Scan time:  5.480

The best scores are:                                      opt bits E(85289)
NP_001791 (OMIM: 600927) cyclin-dependent kinase 4 ( 166) 1064 151.7   5e-37
NP_524145 (OMIM: 600927) cyclin-dependent kinase 4 ( 166) 1064 151.7   5e-37
NP_001253 (OMIM: 603369) cyclin-dependent kinase 4 ( 168)  437 69.5 2.8e-12
NP_523240 (OMIM: 603369) cyclin-dependent kinase 4 ( 168)  437 69.5 2.8e-12
NP_004927 (OMIM: 600431) cyclin-dependent kinase 4 ( 138)  342 57.0 1.4e-08
NP_000068 (OMIM: 155601,155755,600160,606719) cycl ( 156)  338 56.5 2.1e-08
NP_001182061 (OMIM: 155601,155755,600160,606719) c ( 167)  332 55.8 3.9e-08
XP_011515978 (OMIM: 155601,155755,600160,606719) P ( 172)  331 55.6 4.3e-08
XP_011515977 (OMIM: 155601,155755,600160,606719) P ( 184)  331 55.7 4.5e-08
XP_016871638 (OMIM: 600465,615493) PREDICTED: anky (1720)  293 51.9 5.6e-06
XP_016871637 (OMIM: 600465,615493) PREDICTED: anky (1725)  293 51.9 5.6e-06
XP_016871636 (OMIM: 600465,615493) PREDICTED: anky (1735)  293 51.9 5.7e-06
XP_016871635 (OMIM: 600465,615493) PREDICTED: anky (1737)  293 51.9 5.7e-06
XP_016871634 (OMIM: 600465,615493) PREDICTED: anky (1738)  293 51.9 5.7e-06
XP_016871633 (OMIM: 600465,615493) PREDICTED: anky (1741)  293 51.9 5.7e-06
XP_016871632 (OMIM: 600465,615493) PREDICTED: anky (1742)  293 51.9 5.7e-06
XP_016871631 (OMIM: 600465,615493) PREDICTED: anky (1747)  293 51.9 5.7e-06
XP_016871630 (OMIM: 600465,615493) PREDICTED: anky (1751)  293 52.0 5.7e-06
XP_016871629 (OMIM: 600465,615493) PREDICTED: anky (1763)  293 52.0 5.7e-06
XP_016871628 (OMIM: 600465,615493) PREDICTED: anky (1764)  293 52.0 5.7e-06
XP_016871627 (OMIM: 600465,615493) PREDICTED: anky (1785)  293 52.0 5.8e-06
XP_016871626 (OMIM: 600465,615493) PREDICTED: anky (1786)  293 52.0 5.8e-06
XP_016871625 (OMIM: 600465,615493) PREDICTED: anky (1795)  293 52.0 5.8e-06
XP_016871624 (OMIM: 600465,615493) PREDICTED: anky (1838)  293 52.0 5.9e-06
XP_016871623 (OMIM: 600465,615493) PREDICTED: anky (1845)  293 52.0 5.9e-06
XP_016871622 (OMIM: 600465,615493) PREDICTED: anky (1850)  293 52.0 5.9e-06
XP_016871621 (OMIM: 600465,615493) PREDICTED: anky (1855)  293 52.0 5.9e-06
NP_001191332 (OMIM: 600465,615493) ankyrin-3 isofo (1861)  293 52.0 5.9e-06
XP_016871620 (OMIM: 600465,615493) PREDICTED: anky (1862)  293 52.0 5.9e-06
XP_016871619 (OMIM: 600465,615493) PREDICTED: anky (1866)  293 52.0 5.9e-06
NP_001307803 (OMIM: 600465,615493) ankyrin-3 isofo (1867)  293 52.0 5.9e-06
NP_001191333 (OMIM: 600465,615493) ankyrin-3 isofo (1868)  293 52.0 5.9e-06
XP_005269772 (OMIM: 600465,615493) PREDICTED: anky (1885)  293 52.0   6e-06
XP_016871618 (OMIM: 600465,615493) PREDICTED: anky (1888)  293 52.0   6e-06
XP_016871617 (OMIM: 600465,615493) PREDICTED: anky (1889)  293 52.0   6e-06
XP_006717865 (OMIM: 600465,615493) PREDICTED: anky (1898)  293 52.0   6e-06
XP_016871616 (OMIM: 600465,615493) PREDICTED: anky (2603)  293 52.2 7.3e-06
XP_016871615 (OMIM: 600465,615493) PREDICTED: anky (2612)  293 52.2 7.3e-06
XP_016871614 (OMIM: 600465,615493) PREDICTED: anky (2646)  293 52.2 7.3e-06
XP_016871613 (OMIM: 600465,615493) PREDICTED: anky (2647)  293 52.2 7.3e-06
XP_016871612 (OMIM: 600465,615493) PREDICTED: anky (2655)  293 52.2 7.4e-06
XP_011538011 (OMIM: 600465,615493) PREDICTED: anky (2656)  293 52.2 7.4e-06
XP_016871611 (OMIM: 600465,615493) PREDICTED: anky (2728)  293 52.2 7.5e-06
XP_006717859 (OMIM: 600465,615493) PREDICTED: anky (2758)  293 52.2 7.5e-06
XP_011538010 (OMIM: 600465,615493) PREDICTED: anky (2759)  293 52.2 7.5e-06
XP_016871610 (OMIM: 600465,615493) PREDICTED: anky (3945)  293 52.4 9.4e-06
XP_016871609 (OMIM: 600465,615493) PREDICTED: anky (3953)  293 52.4 9.4e-06
XP_016871608 (OMIM: 600465,615493) PREDICTED: anky (3954)  293 52.4 9.4e-06
XP_016871607 (OMIM: 600465,615493) PREDICTED: anky (4057)  293 52.4 9.6e-06
NP_066267 (OMIM: 600465,615493) ankyrin-3 isoform  (4377)  293 52.5   1e-05


>>NP_001791 (OMIM: 600927) cyclin-dependent kinase 4 inh  (166 aa)
 initn: 1064 init1: 1064 opt: 1064  Z-score: 785.8  bits: 151.7 E(85289): 5e-37
Smith-Waterman score: 1064; 100.0% identity (100.0% similar) in 166 aa overlap (1-166:1-166)

               10        20        30        40        50        60
pF1KB8 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT
               70        80        90       100       110       120

              130       140       150       160      
pF1KB8 AVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL
              130       140       150       160      

>>NP_524145 (OMIM: 600927) cyclin-dependent kinase 4 inh  (166 aa)
 initn: 1064 init1: 1064 opt: 1064  Z-score: 785.8  bits: 151.7 E(85289): 5e-37
Smith-Waterman score: 1064; 100.0% identity (100.0% similar) in 166 aa overlap (1-166:1-166)

               10        20        30        40        50        60
pF1KB8 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_524 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_524 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT
               70        80        90       100       110       120

              130       140       150       160      
pF1KB8 AVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL
       ::::::::::::::::::::::::::::::::::::::::::::::
NP_524 AVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL
              130       140       150       160      

>>NP_001253 (OMIM: 603369) cyclin-dependent kinase 4 inh  (168 aa)
 initn: 465 init1: 330 opt: 437  Z-score: 341.5  bits: 69.5 E(85289): 2.8e-12
Smith-Waterman score: 437; 45.8% identity (77.4% similar) in 155 aa overlap (9-161:6-159)

               10        20        30        40        50        60
pF1KB8 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL
               :..:..::::::....  ::. . :. .: : ::.:::::: .:.  :: .:
NP_001    MAEPWGNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRL
                  10        20         30        40        50      

               70        80        90       100       110       120
pF1KB8 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT
       : .::.:...: .: . .:::::.::::::..:.:  ::::. :. : ::.:::..::: 
NP_001 LLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHL
         60        70        80        90       100       110      

                130       140       150       160          
pF1KB8 AVVSFLAAE--SDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL    
        :: ::. .  :.. .:. .: :  .::   : ...:...:..         
NP_001 RVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ
        120       130       140       150       160        

>>NP_523240 (OMIM: 603369) cyclin-dependent kinase 4 inh  (168 aa)
 initn: 465 init1: 330 opt: 437  Z-score: 341.5  bits: 69.5 E(85289): 2.8e-12
Smith-Waterman score: 437; 45.8% identity (77.4% similar) in 155 aa overlap (9-161:6-159)

               10        20        30        40        50        60
pF1KB8 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALEL
               :..:..::::::....  ::. . :. .: : ::.:::::: .:.  :: .:
NP_523    MAEPWGNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRL
                  10        20         30        40        50      

               70        80        90       100       110       120
pF1KB8 LKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHT
       : .::.:...: .: . .:::::.::::::..:.:  ::::. :. : ::.:::..::: 
NP_523 LLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHL
         60        70        80        90       100       110      

                130       140       150       160          
pF1KB8 AVVSFLAAE--SDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL    
        :: ::. .  :.. .:. .: :  .::   : ...:...:..         
NP_523 RVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ
        120       130       140       150       160        

>>NP_004927 (OMIM: 600431) cyclin-dependent kinase 4 inh  (138 aa)
 initn: 373 init1: 209 opt: 342  Z-score: 275.1  bits: 57.0 E(85289): 1.4e-08
Smith-Waterman score: 342; 51.7% identity (75.0% similar) in 116 aa overlap (12-126:18-132)

                     10        20        30        40        50    
pF1KB8       MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGST
                        :..::::: :..::.::.   . :...::::. :.::::.::.
NP_004 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLE-AGADPNGVNRFGRRAIQVMMMGSA
               10        20        30         40        50         

           60        70         80        90       100       110   
pF1KB8 AIALELLKQGASPNVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHL
        .:  :: .:: ::  : .  : ::::::: :::::: :: . :: ..: :. : ::. :
NP_004 RVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL
      60        70        80        90       100       110         

           120       130       140       150       160      
pF1KB8 AVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL
       : ..::  :...:                                        
NP_004 AEERGHRDVAGYLRTATGD                                  
     120       130                                          

>>NP_000068 (OMIM: 155601,155755,600160,606719) cyclin-d  (156 aa)
 initn: 303 init1: 218 opt: 338  Z-score: 271.7  bits: 56.5 E(85289): 2.1e-08
Smith-Waterman score: 338; 44.0% identity (64.7% similar) in 150 aa overlap (8-156:12-156)

                   10        20        30        40        50      
pF1KB8     MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAI
                  ..: :. ::::: :.::: ::.   . :.: : .:.  .::::.::. .
NP_000 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARV
               10        20        30         40        50         

         60        70         80        90       100       110     
pF1KB8 ALELLKQGASPNVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAV
       :  :: .:: ::  : .  : ::::::: :::::: :: . :: ..: :. : ::. :: 
NP_000 AELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAE
      60        70        80        90       100       110         

         120       130       140       150       160      
pF1KB8 QEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL
       . ::  :. .: : .      .:: .  ..   .: .:. :          
NP_000 ELGHRDVARYLRAAAG----GTRGSNHARIDAAEGPSDIPD          
     120       130           140       150                

>>NP_001182061 (OMIM: 155601,155755,600160,606719) cycli  (167 aa)
 initn: 303 init1: 218 opt: 332  Z-score: 267.1  bits: 55.8 E(85289): 3.9e-08
Smith-Waterman score: 332; 43.0% identity (65.1% similar) in 149 aa overlap (8-155:12-155)

                   10        20        30        40        50      
pF1KB8     MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAI
                  ..: :. ::::: :.::: ::.   . :.: : .:.  .::::.::. .
NP_001 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARV
               10        20        30         40        50         

         60        70         80        90       100       110     
pF1KB8 ALELLKQGASPNVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAV
       :  :: .:: ::  : .  : ::::::: :::::: :: . :: ..: :. : ::. :: 
NP_001 AELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAE
      60        70        80        90       100       110         

         120       130       140       150       160       
pF1KB8 QEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL 
       . ::  :. .: : .      .:: .  ..   .: ....            
NP_001 ELGHRDVARYLRAAAG----GTRGSNHARIDAAEGPSEMIGNHLWVCRSRHA
     120       130           140       150       160       

>>XP_011515978 (OMIM: 155601,155755,600160,606719) PREDI  (172 aa)
 initn: 303 init1: 218 opt: 331  Z-score: 266.3  bits: 55.6 E(85289): 4.3e-08
Smith-Waterman score: 331; 50.0% identity (68.9% similar) in 122 aa overlap (8-128:12-132)

                   10        20        30        40        50      
pF1KB8     MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAI
                  ..: :. ::::: :.::: ::.   . :.: : .:.  .::::.::. .
XP_011 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARV
               10        20        30         40        50         

         60        70         80        90       100       110     
pF1KB8 ALELLKQGASPNVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAV
       :  :: .:: ::  : .  : ::::::: :::::: :: . :: ..: :. : ::. :: 
XP_011 AELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAE
      60        70        80        90       100       110         

         120       130       140       150       160        
pF1KB8 QEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL  
       . ::  :. .: :                                        
XP_011 ELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSVTASIQVPGGEEGDFGSSYS
     120       130       140       150       160       170  

>>XP_011515977 (OMIM: 155601,155755,600160,606719) PREDI  (184 aa)
 initn: 303 init1: 218 opt: 331  Z-score: 265.9  bits: 55.7 E(85289): 4.5e-08
Smith-Waterman score: 331; 50.0% identity (68.9% similar) in 122 aa overlap (8-128:12-132)

                   10        20        30        40        50      
pF1KB8     MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAI
                  ..: :. ::::: :.::: ::.   . :.: : .:.  .::::.::. .
XP_011 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARV
               10        20        30         40        50         

         60        70         80        90       100       110     
pF1KB8 ALELLKQGASPNVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAV
       :  :: .:: ::  : .  : ::::::: :::::: :: . :: ..: :. : ::. :: 
XP_011 AELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAE
      60        70        80        90       100       110         

         120       130       140       150       160               
pF1KB8 QEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL         
       . ::  :. .: :                                               
XP_011 ELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSAGWTNLRISKPNCAWHHLEISRSRLFC
     120       130       140       150       160       170         

>>XP_016871638 (OMIM: 600465,615493) PREDICTED: ankyrin-  (1720 aa)
 initn: 638 init1: 203 opt: 293  Z-score: 228.3  bits: 51.9 E(85289): 5.6e-06
Smith-Waterman score: 293; 37.5% identity (65.1% similar) in 152 aa overlap (16-163:555-706)

                              10        20        30        40     
pF1KB8                MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTA
                                     ::.    ::  :: .. . ::: .. : : 
XP_016 EGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTP
          530       540       550       560       570       580    

          50         60        70        80        90       100    
pF1KB8 LQVMM-FGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPD
       :.:   . .  .:: :: :::::..   .: .:.: ::. . .:   .:.:.:::.:.  
XP_016 LHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVT
          590       600       610       620       630       640    

          110       120       130        140       150         160 
pF1KB8 GTGALPIHLAVQEGHTAVVSFLAAES-DLHRRDARGLTPLELALQRGAQDLVDIL--QGH
         :   .:::.::::. .::.: ... ...  .  :::::.:: :.   .....:  :: 
XP_016 RQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGA
          650       660       670       680       690       700    

                                                                   
pF1KB8 MVAPL                                                       
        :                                                          
XP_016 HVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINV
          710       720       730       740       750       760    




166 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 20:19:40 2016 done: Fri Nov  4 20:19:40 2016
 Total Scan time:  5.480 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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