Result of FASTA (omim) for pF1KE0219
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0219, 162 aa
  1>>>pF1KE0219 162 - 162 aa - 162 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.8841+/-0.000373; mu= 14.6137+/- 0.023
 mean_var=60.9750+/-12.708, 0's: 0 Z-trim(112.8): 19  B-trim: 479 in 1/48
 Lambda= 0.164247
 statistics sampled from 21855 (21869) to 21855 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.256), width:  16
 Scan time:  5.110

The best scores are:                                      opt bits E(85289)
NP_001224 (OMIM: 601048) caveolin-2 isoform a [Hom ( 162) 1092 266.9   1e-71
NP_001193676 (OMIM: 601048) caveolin-2 isoform b [ ( 149) 1011 247.7 5.7e-66
NP_001193677 (OMIM: 601048) caveolin-2 isoform d [ (  79)  522 131.6 2.6e-31
NP_001166366 (OMIM: 601047,606721,612526,615343) c ( 147)  355 92.2 3.5e-19
NP_001166368 (OMIM: 601047,606721,612526,615343) c ( 147)  355 92.2 3.5e-19
NP_001166367 (OMIM: 601047,606721,612526,615343) c ( 147)  355 92.2 3.5e-19
NP_001744 (OMIM: 601047,606721,612526,615343) cave ( 178)  355 92.3 4.1e-19
NP_937855 (OMIM: 601048) caveolin-2 isoform c [Hom ( 112)  346 90.0 1.2e-18
NP_001225 (OMIM: 123320,192600,601253,606072,60780 ( 151)  327 85.6 3.6e-17
NP_203123 (OMIM: 123320,192600,601253,606072,60780 ( 151)  327 85.6 3.6e-17


>>NP_001224 (OMIM: 601048) caveolin-2 isoform a [Homo sa  (162 aa)
 initn: 1092 init1: 1092 opt: 1092  Z-score: 1408.5  bits: 266.9 E(85289): 1e-71
Smith-Waterman score: 1092; 100.0% identity (100.0% similar) in 162 aa overlap (1-162:1-162)

               10        20        30        40        50        60
pF1KE0 MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 VTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVK
               70        80        90       100       110       120

              130       140       150       160  
pF1KE0 TCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 TCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
              130       140       150       160  

>>NP_001193676 (OMIM: 601048) caveolin-2 isoform b [Homo  (149 aa)
 initn: 1011 init1: 1011 opt: 1011  Z-score: 1305.3  bits: 247.7 E(85289): 5.7e-66
Smith-Waterman score: 1011; 100.0% identity (100.0% similar) in 149 aa overlap (14-162:1-149)

               10        20        30        40        50        60
pF1KE0 MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEP
                    :::::::::::::::::::::::::::::::::::::::::::::::
NP_001              MDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEP
                            10        20        30        40       

               70        80        90       100       110       120
pF1KE0 VTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVK
        50        60        70        80        90       100       

              130       140       150       160  
pF1KE0 TCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 TCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
       110       120       130       140         

>>NP_001193677 (OMIM: 601048) caveolin-2 isoform d [Homo  (79 aa)
 initn: 522 init1: 522 opt: 522  Z-score: 683.1  bits: 131.6 E(85289): 2.6e-31
Smith-Waterman score: 522; 100.0% identity (100.0% similar) in 79 aa overlap (84-162:1-79)

            60        70        80        90       100       110   
pF1KE0 EDVIAEPVTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIW
                                     ::::::::::::::::::::::::::::::
NP_001                               MYKFLTVFLAIPLAFIAGILFATLSCLHIW
                                             10        20        30

           120       130       140       150       160  
pF1KE0 ILMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
               40        50        60        70         

>>NP_001166366 (OMIM: 601047,606721,612526,615343) caveo  (147 aa)
 initn: 359 init1: 321 opt: 355  Z-score: 465.3  bits: 92.2 E(85289): 3.5e-19
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (39-162:22-146)

       10        20        30        40         50        60       
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
                                     .:::..::. . :. ::::::::  :::::
NP_001          MADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
                        10        20        30        40        50 

        70        80        90       100       110       120       
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
        .:  : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. . 
NP_001 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
              60        70        80        90       100       110 

       130       140       150       160   
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD 
        .. ...  . ..  ::  .::. ::.: ..:... 
NP_001 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
             120       130       140       

>>NP_001166368 (OMIM: 601047,606721,612526,615343) caveo  (147 aa)
 initn: 359 init1: 321 opt: 355  Z-score: 465.3  bits: 92.2 E(85289): 3.5e-19
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (39-162:22-146)

       10        20        30        40         50        60       
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
                                     .:::..::. . :. ::::::::  :::::
NP_001          MADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
                        10        20        30        40        50 

        70        80        90       100       110       120       
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
        .:  : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. . 
NP_001 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
              60        70        80        90       100       110 

       130       140       150       160   
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD 
        .. ...  . ..  ::  .::. ::.: ..:... 
NP_001 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
             120       130       140       

>>NP_001166367 (OMIM: 601047,606721,612526,615343) caveo  (147 aa)
 initn: 359 init1: 321 opt: 355  Z-score: 465.3  bits: 92.2 E(85289): 3.5e-19
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (39-162:22-146)

       10        20        30        40         50        60       
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
                                     .:::..::. . :. ::::::::  :::::
NP_001          MADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
                        10        20        30        40        50 

        70        80        90       100       110       120       
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
        .:  : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. . 
NP_001 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
              60        70        80        90       100       110 

       130       140       150       160   
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD 
        .. ...  . ..  ::  .::. ::.: ..:... 
NP_001 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
             120       130       140       

>>NP_001744 (OMIM: 601047,606721,612526,615343) caveolin  (178 aa)
 initn: 359 init1: 321 opt: 355  Z-score: 464.1  bits: 92.3 E(85289): 4.1e-19
Smith-Waterman score: 355; 40.8% identity (74.4% similar) in 125 aa overlap (39-162:53-177)

       10        20        30        40         50        60       
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
                                     .:::..::. . :. ::::::::  :::::
NP_001 NIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFD
             30        40        50        60        70        80  

        70        80        90       100       110       120       
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
        .:  : . : ..:: .:..:.....::.:.: :: :: :: :::: ..: .:. :. . 
NP_001 GIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQ
             90       100       110       120       130       140  

       130       140       150       160   
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD 
        .. ...  . ..  ::  .::. ::.: ..:... 
NP_001 CISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
            150       160       170        

>>NP_937855 (OMIM: 601048) caveolin-2 isoform c [Homo sa  (112 aa)
 initn: 358 init1: 346 opt: 346  Z-score: 455.5  bits: 90.0 E(85289): 1.2e-18
Smith-Waterman score: 346; 100.0% identity (100.0% similar) in 50 aa overlap (1-50:1-50)

               10        20        30        40        50        60
pF1KE0 MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
NP_937 MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKDFNAFCKDLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 VTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVK
                                                                   
NP_937 NGSAFSADNMEECDRCYHCSIVYERRTMLLFCQPATEPGLNTWTPGLEIGIL        
               70        80        90       100       110          

>>NP_001225 (OMIM: 123320,192600,601253,606072,607801,61  (151 aa)
 initn: 332 init1: 298 opt: 327  Z-score: 429.3  bits: 85.6 E(85289): 3.6e-17
Smith-Waterman score: 327; 39.2% identity (72.0% similar) in 125 aa overlap (39-162:26-150)

       10        20        30        40         50        60       
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
                                     .:::. .:  . :. ::::::::: :.:::
NP_001      MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFD
                    10        20        30        40        50     

        70        80        90       100       110       120       
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
        ::  :.. : .:::  :..:...:..:::.. :.::: .:  ::: ..: .:. :. . 
NP_001 GVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQ
          60        70        80        90       100       110     

       130       140       150       160   
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD 
        .. :..    ..  :: ...:.  ::... : .. 
NP_001 CISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
         120       130       140       150 

>>NP_203123 (OMIM: 123320,192600,601253,606072,607801,61  (151 aa)
 initn: 332 init1: 298 opt: 327  Z-score: 429.3  bits: 85.6 E(85289): 3.6e-17
Smith-Waterman score: 327; 39.2% identity (72.0% similar) in 125 aa overlap (39-162:26-150)

       10        20        30        40         50        60       
pF1KE0 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
                                     .:::. .:  . :. ::::::::: :.:::
NP_203      MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFD
                    10        20        30        40        50     

        70        80        90       100       110       120       
pF1KE0 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
        ::  :.. : .:::  :..:...:..:::.. :.::: .:  ::: ..: .:. :. . 
NP_203 GVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQ
          60        70        80        90       100       110     

       130       140       150       160   
pF1KE0 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD 
        .. :..    ..  :: ...:.  ::... : .. 
NP_203 CISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
         120       130       140       150 




162 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 01:49:39 2016 done: Sat Nov  5 01:49:40 2016
 Total Scan time:  5.110 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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